- Article
Targeting BRF2 in Cancer Using Repurposed Drugs
- Behnam Rashidieh,
- Maryam Molakarimi,
- Ammar Mohseni,
- Simon Manuel Tria,
- Hein Truong,
- Sriganesh Srihari,
- Rachael C. Adams,
- Mathew Jones,
- Pascal H. G. Duijf and
- Kum Kum Khanna
- + 1 author
The overexpression of BRF2, a selective subunit of RNA polymerase III, has been shown to be crucial in the development of several types of cancers, including breast cancer and lung squamous cell carcinoma. Predominantly, BRF2 acts as a central redox-...