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1,267 Results Found

  • Article
  • Open Access
10 Citations
10,526 Views
10 Pages

Facial wrinkles (considered to be natural features) appear as people get older. Wrinkle detection is an important aspect of applications that depend on facial skin changes, such as face age estimation and soft biometrics. While existing wrinkle detec...

  • Article
  • Open Access
8 Citations
2,774 Views
14 Pages

Conducting a wrinkling analysis for a membrane structure of complex boundary conditions is quite difficult. This paper develops a numerical calculation method for completing a wrinkling analysis of a square membrane structure and a trapezoidal membra...

  • Article
  • Open Access
6 Citations
5,551 Views
15 Pages

Fine Wrinkle Improvement through Bioactive Materials That Modulate EDAR and BNC2 Gene Expression

  • Seonju Lee,
  • Sanghyun Ye,
  • Mina Kim,
  • Hyejin Lee,
  • Seung-Hyun Jun and
  • Nae-Gyu Kang

26 February 2024

Skin aging is a multifaceted biological phenomenon influenced by a combination of intrinsic or extrinsic factors. There is an increasing interest in anti-aging materials including components that improve skin wrinkles. Despite the availability of sev...

  • Article
  • Open Access
5 Citations
3,341 Views
10 Pages

Effect of Low-Pressure Plasma Treatment Parameters on Wrinkle Features

  • Bongjun Gu,
  • Dongwook Ko,
  • Sungjin Jo,
  • Dong Choon Hyun,
  • Hyeon-Ju Oh and
  • Jongbok Kim

1 September 2020

Wrinkles attract significant attention due to their ability to enhance the mechanical and optical characteristics of various optoelectronic devices. We report the effect of the plasma gas type, power, flow rate, and treatment time on the wrinkle feat...

  • Article
  • Open Access
12 Citations
5,303 Views
12 Pages

Voltage-Induced Wrinkle Performance in a Hydrogel by Dielectric Elastomer Actuation

  • Chao Tang,
  • Bo Li,
  • Chenbang Zou,
  • Lei Liu and
  • Hualing Chen

22 June 2018

Hydrogel is a type of soft smart material and is responsive to stimuli. In the development of actuation in hydrogel, electrical actuation features a fast and universal strategy which is favored in the engineering system. Due to the difficulty in dire...

  • Article
  • Open Access
5 Citations
2,405 Views
16 Pages

29 July 2022

The stiffness of composite laminates is easily affected by wrinkle defects. In this paper, a new effective analytical model was proposed to predict the three-dimensional equivalent elastic properties of multidirectional composite laminates with wrink...

  • Article
  • Open Access
1 Citations
3,239 Views
11 Pages

22 April 2021

In this study, we introduce a new wrinkle method for intracorporeal anterior vaginal wall plication during sacrocolpopexy for pelvic organ prolapse (POP) aiming to decrease POP recurrence and postoperative vaginal wall mesh erosion. The wrinkle metho...

  • Article
  • Open Access
35 Citations
4,304 Views
14 Pages

Adsorption of Cellulase on Wrinkled Silica Nanoparticles with Enhanced Inter-Wrinkle Distance

  • Aniello Costantini,
  • Virginia Venezia,
  • Giulio Pota,
  • Aurelio Bifulco,
  • Valeria Califano and
  • Filomena Sannino

10 September 2020

Mesoporous silica materials offer a unique opportunity for enzyme immobilization thanks to their properties, such as tuneable pore size, large surface area and easy functionalization. However, a significant enhancement of cellulase enzyme activity en...

  • Article
  • Open Access
1 Citations
5,866 Views
14 Pages

Wrinkle-Improving Effect of Novel Peptide That Binds to Nicotinic Acetylcholine Receptor

  • Jinho Bang,
  • Yul-Lye Hwang,
  • Mi Yoon Kim,
  • Jae Nam Yun,
  • Eujin Hyun,
  • Min Youl Chang,
  • Dae Hwan Shin,
  • Sunghyun Kim and
  • Jeung-Hoon Lee

Wrinkles, one of the most common signs of aging, are primarily caused by the continuous contraction of muscles. Muscle contraction is induced by the binding of acetylcholine (ACh), released at the neuromuscular junction, to nicotinic acetylcholine re...

  • Article
  • Open Access
6 Citations
4,397 Views
13 Pages

19 May 2021

In the anti-wrinkle finishing of cotton fabrics, the decreased dyeability of the finished fabrics has always been a difficult problem. A new anti-wrinkle finishing mode was developed to solve this problem by changing the finishing sequence of fabric...

  • Review
  • Open Access
18 Citations
9,913 Views
23 Pages

3D Printed Hollow Microneedles for Treating Skin Wrinkles Using Different Anti-Wrinkle Agents: A Possible Futuristic Approach

  • Humayra Islam,
  • Taslima Sultana Poly,
  • Zarin Tasnim Tisha,
  • Samia Rahman,
  • Ahmed Issa Jahangir Naveed,
  • Alifa Ahmed,
  • Saraf Nawar Ahmed,
  • Jasmin Hassan,
  • Md. Jasim Uddin and
  • Diganta B. Das

27 February 2023

Skin wrinkles are an inevitable phenomenon that is brought about by aging due to the degradation of scleroprotein fibers and significant collagen reduction, which is the fundamental basis of anti-wrinkle technology in use today. Conventional treatmen...

  • Article
  • Open Access
5 Citations
2,367 Views
17 Pages

25 December 2022

Composite pressure vessels (CPVs) have become the main equipment for hydrogen storage; however, the effect of defect in the laminates of CPVs is difficult to detect. In this paper, composite specimens containing wrinkle defects were investigated, and...

  • Article
  • Open Access
11 Citations
3,009 Views
15 Pages

9 November 2021

This paper aims to study the wrinkle formation of a prepreg with initial defect during steering in automated fiber placement (AFP). Wrinkle formation has a detrimental effect on the mechanical properties of the final product, limiting the AFP applica...

  • Article
  • Open Access
5 Citations
908 Views
22 Pages

15 May 2025

Carbon fiber-reinforced polymer (CFRP) has become widely applied in engineering fields such as aerospace and the automotive industries. Evaluating the damage tolerance of CFRP with manufacturing defects under impact loads is crucial in ensuring the r...

  • Article
  • Open Access
9 Citations
3,664 Views
15 Pages

Improving Interaction at Polymer–Filler Interface: The Efficacy of Wrinkle Texture

  • Pietro Russo,
  • Virginia Venezia,
  • Fabiana Tescione,
  • Joshua Avossa,
  • Giuseppina Luciani,
  • Brigida Silvestri and
  • Aniello Costantini

25 January 2020

One of the main issues in preparing polymer-based nanocomposites with effective properties is to achieve a good dispersion of the nanoparticles into the matrix. Chemical interfacial modifications by specific coupling agents represents a good way to r...

  • Article
  • Open Access
2 Citations
2,997 Views
12 Pages

14 March 2023

Synthesis of a smooth conductive film over an elastomer is vital to the development of flexible optics and wearable electronics, but applications are hindered by wrinkles and cracks in the film. To date, a large-scale wrinkle-free film in an elastome...

  • Article
  • Open Access
7 Citations
4,358 Views
8 Pages

Ring Wrinkle Patterns with Continuously Changing Wavelength Produced Using a Controlled-Gradient Light Field

  • Hongye Li,
  • Bin Sheng,
  • He Wu,
  • Yuanshen Huang,
  • Dawei Zhang and
  • Songlin Zhuang

1 September 2018

We report a facile method to prepare gradient wrinkles using a controlled-gradient light field. Because of the gradient distance between the ultraviolet (UV) lamp and polydimethylsiloxane (PDMS) substrate during UV/ozone treatment, the irradiance rea...

  • Review
  • Open Access
11 Citations
39,647 Views
15 Pages

Sustainable Dynamic Wrinkle Efficacy: Non-Invasive Peptides as the Future of Botox Alternatives

  • Trang Thi Minh Nguyen,
  • Eun-Ji Yi,
  • Xiangji Jin,
  • Qiwen Zheng,
  • Se-Jig Park,
  • Gyeong-Seon Yi,
  • Su-Jin Yang and
  • Tae-Hoo Yi

Dynamic wrinkle reduction continues to challenge aesthetic dermatology, predominantly addressed through Botulinumtoxin (Botox) injections. Despite Botox’s robust efficacy with up to an 80% reduction in wrinkle visibility within just one week, i...

  • Article
  • Open Access
13 Citations
5,622 Views
12 Pages

Web Wrinkle Defects due to Temperature Profile in Roll-to-Roll Manufacturing Systems

  • Jaehyun Noh,
  • Minho Jo,
  • Hojin Jeon,
  • Minjae Kim,
  • Jeongdai Jo and
  • Changwoo Lee

15 January 2023

The roll-to-roll manufacturing system is extensively used for mass producing products made of plastic, paper, and fabric in several traditional industries. When flexible substrates, also known as webs, are heated and transported inside the dryer, an...

  • Article
  • Open Access
4 Citations
4,356 Views
20 Pages

5 December 2023

Wrinkles, crucial for age estimation and skin quality assessment, present challenges due to their uneven distribution, varying scale, and sensitivity to factors like lighting. To overcome these challenges, this study presents facial wrinkle detection...

  • Letter
  • Open Access
1 Citations
5,382 Views
4 Pages

Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers

  • Da Jung Kim,
  • Seul Bi Lee,
  • Song Sun Chang and
  • Jungsun Lee

This letter is intended to clarify the clinical effectiveness of neuropeptide substance P (SP) in reducing age-related skin wrinkling. This is the first clinical study to evaluate the efficacy of the topical application of SP on wrinkle reduction. Fo...

  • Article
  • Open Access
868 Views
19 Pages

Copper–PLLA-Based Biopolymer Wrinkle Structures for Enhanced Antibacterial Activity

  • Petr Slepička,
  • Iva Labíková,
  • Bára Frýdlová,
  • Aneta Pagáčová,
  • Nikola Slepičková Kasálková,
  • Petr Sajdl and
  • Václav Švorčík

8 August 2025

The increasing prevalence of antibiotic-resistant bacteria has intensified the need for innovative antibacterial surfaces, particularly in biomedical applications. Traditional approaches often rely on chemical agents alone, which may lead to diminish...

  • Article
  • Open Access
10 Citations
3,964 Views
26 Pages

25 May 2020

Out-of-plane wrinkling has a significant influence on the mechanical performance of composite laminates. Numerical simulations were conducted to investigate the progressive failure behavior of fiber-reinforced composite laminates with out-of-plane wr...

  • Article
  • Open Access
9 Citations
3,937 Views
17 Pages

7 October 2022

Surface wrinkling instability in thin films attached to a compliant substrate is a well-recognized form of deformation under mechanical loading. The influence of the loading history on the formation of instability patterns has not been studied. In th...

  • Article
  • Open Access
20 Citations
4,264 Views
14 Pages

15 February 2023

Carbon fiber-reinforced polymers (CFRP) are extensively used in aerospace applications. Out-of-plane wrinkles frequently occur in aerospace CFRP parts that are commonly large and complex. Wrinkles acting as failure initiators severely damage the mech...

  • Article
  • Open Access
15 Citations
9,183 Views
19 Pages

4 June 2013

We here present the nucleation and growth of calcium carbonate under the influence of synthetic peptides on topographically patterned poly(dimethylsiloxane) (PDMS) substrates, which have a controlled density of defects between the wrinkles. Experimen...

  • Article
  • Open Access
18 Citations
6,319 Views
12 Pages

Anti-Wrinkle Effect of Isatis indigotica Leaf Extract: Evaluation of Antioxidant, Anti-Inflammation, and Clinical Activity

  • Jin Hyeok Kim,
  • Dan Gao,
  • Won Seok Jeong,
  • Cheong Taek Kim,
  • Chong Woon Cho,
  • Hyung Min Kim and
  • Jong Seong Kang

25 August 2021

Isatis indigotica leaf is an oriental herbal medicine that has been known for various pharmacological effects. However, its anti-wrinkle activity has not been fully evaluated. Therefore, we evaluated the anti-wrinkle effect of I. indigotica leaf extr...

  • Article
  • Open Access
11 Citations
4,356 Views
12 Pages

15 February 2022

In this study, ultrasound-assisted extraction (UAE) was applied to extract bioactive substances with skin-whitening, anti-wrinkle, and antioxidant effects from safflower seeds, and the extraction conditions were optimized by a central composite desig...

  • Article
  • Open Access
2 Citations
9,726 Views
13 Pages

Peptides, composed of 2–50 amino acids, have gained attention in anti-aging treatments due to their high safety, low irritation, and cost-effective production. This study aimed to evaluate the anti-wrinkle efficacy of Tetrapeptide-68, derived f...

  • Article
  • Open Access
3 Citations
2,279 Views
12 Pages

15 April 2025

Flexible pressure sensors have garnered significant attention due to their wide range of applications in human motion monitoring and smart wearable devices. However, the fabrication of pressure sensors that offer both high sensitivity and a wide dete...

  • Article
  • Open Access
2 Citations
1,385 Views
19 Pages

Characterization and Modeling of Out-of-Plane Behavior of Fiber-Based Materials: Numerical Illustration of Wrinkle in Deep Drawing

  • Cedric W. Sanjon,
  • Yuchen Leng,
  • Yi Yan,
  • Peter Groche,
  • Marek Hauptmann,
  • Nicole Ludat and
  • Jens-Peter Majschak

23 August 2024

The characterization and modeling of the out-of-plane behavior of fiber-based materials is essential for understanding their mechanical properties and improving their performance in various applications, especially in the forming process. Despite thi...

  • Article
  • Open Access
60 Citations
23,018 Views
12 Pages

Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression

  • Sekyoo Jeong,
  • Seokjeong Yoon,
  • Sungwoo Kim,
  • Juyeon Jung,
  • Myungho Kor,
  • Kayoung Shin,
  • Chaejin Lim,
  • Hyo Sun Han,
  • Haekwang Lee and
  • Kyeong-Yong Park
  • + 3 authors

The dermal-epidermal junction (DEJ) provides a physical and biological interface between the epidermis and the dermis. In addition to providing a structural integrity, the DEJ also acts as a passageway for molecular transport. Based on the recently r...

  • Article
  • Open Access
5 Citations
4,361 Views
16 Pages

The Safety and Efficacy of 1-Monoeicosapentaenoin Isolated from the Trebouxiophyceae Micractinium on Anti-Wrinkle: A Split-Face Randomized, Double-Blind Placebo-Controlled Clinical Study

  • Ki Mo Kim,
  • Kon-Young Ji,
  • Yoon Jung Choi,
  • Jong Beom Heo,
  • Ui Joung Youn,
  • Sanghee Kim,
  • Ki-Shuk Shim,
  • Joo Young Lee,
  • Tae Soo Kim and
  • Young Kyoung Seo
  • + 2 authors

11 January 2023

The skin aging process is governed by intrinsic and extrinsic factors causing skin wrinkles, sagging, and loosening. The 1-monoeicosapentaenoin (1-MEST) is a component isolated from Micractinium, a genus of microalgae (Chlorophyta, Trebouxiophyceae)....

  • Article
  • Open Access
3 Citations
3,137 Views
14 Pages

19 November 2021

In this paper, monosaccharide (glucose and fructose), disaccharide (sucrose and trehalose), trisaccharide (raffinose) and tetrasaccharide (stachyose) were selected as the research objects and the glycosyl polyaldehydes and glycosyl polyuronic acid an...

  • Article
  • Open Access
9 Citations
3,292 Views
18 Pages

Soybean-derived peptides exert several beneficial effects in various experimental models. However, only a few studies have focused on the radical scavenging and anti-wrinkle effects of soymilk-derived peptides produced via different processes, such a...

  • Article
  • Open Access
13 Citations
5,202 Views
12 Pages

Genetic and environmental factors influence wrinkle development. We evaluated the polygenetic risk score (PRS) by pooling the selected single nucleotide polymorphisms (SNPs) from a genome-wide association study (GWAS) for wrinkles and the interaction...

  • Article
  • Open Access
9 Citations
4,906 Views
14 Pages

21 January 2021

Here, we investigated the effects of Zingiber mioga extracts (FSH-ZM) on the moisturization and depigmentation of skin as well as wrinkle formation in UVB-irradiated HRM-2 hairless mice. The mice were divided into six groups as follows: normal contro...

  • Review
  • Open Access
412 Views
35 Pages

30 December 2025

Background: Fine particulate matter (PM2.5) is an established systemic toxicant, yet its association with clinical skin aging remains incompletely characterized. Although pigmentary changes and wrinkles are commonly attributed to ultraviolet exposure...

  • Article
  • Open Access
6 Citations
8,042 Views
18 Pages

Formulation and Evaluation of Radiance Serum Containing Astaxanthin–Zeaxanthin Nanoemulsions as an Anti-Wrinkle Agent: Stability, Ex Vivo, and In Vivo Assessments

  • Lusi Nurdianti,
  • Fajar Setiawan,
  • Ira Maya,
  • Taofik Rusdiana,
  • Cahya Khairani Kusumawulan,
  • Dolih Gozali and
  • Dewi Peti Virgianti

17 October 2024

Reactive oxygen species (ROS), commonly known as free radicals, induced by UV radiation can compromise the dermal structure, leading to a loss of skin elasticity and subsequent wrinkle formation. A promising strategy to prevent and mitigate skin agin...

  • Article
  • Open Access
4 Citations
1,969 Views
22 Pages

Background/Objectives: Skin wrinkles result from a myriad of multifaceted processes involving intrinsic and extrinsic aging. To combat this effect, plant stem cells offer a renewable and eco-friendly source for various industries, including cosmeceut...

  • Article
  • Open Access
49 Citations
6,806 Views
17 Pages

Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice

  • Da-Bin Myung,
  • Hee-Soo Han,
  • Ji-Sun Shin,
  • Ji Yeon Park,
  • Han Jun Hwang,
  • Hyoung Ja Kim,
  • Hye Shin Ahn,
  • Sun Hee Lee and
  • Kyung-Tae Lee

2 October 2019

Our previous study showed that hydrangenol isolated from Hydrangea serrata leaves exerts antiphotoaging activity in vitro. In this study, we determined its antiphotoaging effect in UVB-irradiated HR-1 hairless mice. We evaluated wrinkle formation, sk...

  • Brief Report
  • Open Access
1,025 Views
12 Pages

3 December 2025

Since the causes of aging are diverse, anti-aging requires a wide range of strategies. Kampo, a traditional medicine of Japan, which has its roots in traditional Chinese medicine, is generally prepared by combining several natural compounds to produc...

  • Article
  • Open Access
6 Citations
11,293 Views
15 Pages

Skin aging is a biological process leading to visible skin alterations. The mechanism of action, clinical efficacy and tolerance of a novel anti-wrinkle technology were evaluated in two skin care products formulated for different skin types. Two sing...

  • Article
  • Open Access
1,956 Views
12 Pages

Development of New Anti-Wrinkle Peptide Using Cheminformatics-Assisted Peptidomimetic Design

  • Soyoon Baek,
  • Sekyoo Jeong,
  • Seokjeong Yoon,
  • Yeonjae Kim,
  • Sungwoo Kim,
  • Hwa-Jee Chung,
  • Hyun-Jung Kim,
  • In Ki Hong and
  • Gaewon Nam

15 November 2025

Peptides are recognized as multifunctional bioactive ingredients in cosmetic science, as they offer diverse beneficial effects such as skin rejuvenation, anti-aging, and skin barrier enhancement. In this study, we applied a cheminformatics-assisted p...

  • Article
  • Open Access
8 Citations
3,519 Views
20 Pages

11 June 2022

Hybrid free-radical/cationic systems can generate phase-separated polymers or interpenetrating networks driven by photopolymerization. In this study, phase separation of a ternary mixture composed of a polybutadiene urethane diacrylate (PBUDA), a cyc...

  • Article
  • Open Access
2 Citations
3,010 Views
14 Pages

27 February 2024

As the aging population increases, so has interest among emerging seniors in anti-aging ingredients that enhance functionality by incorporating fermentation with natural materials. In this study, fermentation conditions for enhancing the functionalit...

  • Article
  • Open Access
5 Citations
7,984 Views
9 Pages

Randomized Double-Blind Placebo-Controlled Supplementation with Standardized Terminalia chebula Fruit Extracts Reduces Facial Sebum Excretion, Erythema, and Wrinkle Severity

  • Mincy Chakkalakal,
  • Adrianne Pan,
  • Dawnica Nadora,
  • Nimrit Gahoonia,
  • Ratan K. Chaudhuri,
  • Waqas Burney,
  • Shivani Thacker,
  • Anastasia Shakhbazova,
  • Chaitra Subramanyam and
  • Cindy J. Chambers
  • + 1 author

17 February 2023

Terminalia chebula (TC) is a medicinal plant that exhibits antioxidant, anti-inflammatory, and antibacterial properties and that is widely used in Ayurveda and herbal formulations. However, the skin effects of TC as an oral supplement have not been s...

  • Article
  • Open Access
2,486 Views
21 Pages

The metal spinning process has been observed in recent major investigations carried out using finite element analysis. One interesting idea has proposed simulating a rotating disc for the simulation of the metal spinning process to reduce computation...

  • Article
  • Open Access
18 Citations
5,340 Views
15 Pages

25 February 2021

Response surface methodology was employed to optimize the ultrasound-assisted extraction (UAE) conditions for simultaneous optimization of dependent variables, including DPPH radical scavenging activity (RSA), tyrosinase activity inhibition (TAI), an...

  • Article
  • Open Access
14 Citations
3,355 Views
16 Pages

Skin Wound Healing and Anti-Wrinkle-Promoting In Vitro Biological Activities of Caragana sinica Flower Absolute and Its Chemical Composition

  • Mi Jung Kim,
  • Kyung Jong Won,
  • Do Yoon Kim,
  • Yu Rim Won,
  • Nan Young Kim,
  • Da Kyoung Lee,
  • Bok Sil Hong and
  • Hwan Myung Lee

3 February 2023

Caragana sinica (CS; family Legume) was used as a medicinal material to treat neuralgia and arthritis in folk remedies and has been shown to have antioxidant, neuroprotective, and anti-apoptotic effects. However, CS is unknown for its biological acti...

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