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Open AccessLetter

Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers

Research and Development Institute, Biosolution, Seoul Technopark, 232 Gongneung-ro, Nowon-gu, Seoul 01811, Korea
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Cosmetics 2020, 7(2), 37; https://doi.org/10.3390/cosmetics7020037
Received: 2 April 2020 / Revised: 19 May 2020 / Accepted: 20 May 2020 / Published: 21 May 2020
This letter is intended to clarify the clinical effectiveness of neuropeptide substance P (SP) in reducing age-related skin wrinkling. This is the first clinical study to evaluate the efficacy of the topical application of SP on wrinkle reduction. For the clinical study, we tested the efficacy of a stable SP formulation known as SP-based hydrogel against skin aging in study participants. We found that this SP-based hydrogel reduced skin aging based on changes observed in several cutaneous parameters. View Full-Text
Keywords: substance P; hydrogel; anti-wrinkle efficacy; clinical study; cosmeceutical substance P; hydrogel; anti-wrinkle efficacy; clinical study; cosmeceutical
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MDPI and ACS Style

Kim, D.J.; Lee, S.B.; Chang, S.S.; Lee, J. Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers. Cosmetics 2020, 7, 37.

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