Objectives: This study aimed to analyse blood glucose and lipid levels in subjective tinnitus compared to healthy controls. Method: A total of 414 patients with subjective tinnitus and 274 healthy participants were enrolled. All participants underwen...
The triglyceride–glucose (TyG) index has been correlated with insulin resistance. We aim to investigate the role of the TyG index on cardiovascular (CV) events in type 2 diabetes mellitus and compare the roles of fasting glucose, hemoglobin A1c...
Background: This study aimed to investigate the association between metabolic and atherogenic indices and erectile dysfunction (ED) severity, and to compare their diagnostic performance in predicting severe ED. Methods: This retrospective study inclu...
Background: Vitamin D deficiency (VDD) increases the risk for type 2 diabetes mellitus (T2DM), which might be related to insulin resistance (IR). We aimed to explore the association between the triglyceride-glucose (TyG) index, a reliable indicator o...
Obstructive sleep apnoea (OSA) is associated with increased insulin resistance. Triglyceride-glucose index (TyG) is a simple marker of insulin resistance; however, it has been investigated only by two studies in OSA. The aim of this study was to eval...
Background and Objectives: The myocardial performance index (MPI) is a diagnostic tool that assesses both the systolic and diastolic function of ventricles. The MPI provides a comprehensive view of the overall efficiency of the heart’s pumping...
Background: In this study, we aimed to investigate the relationship between diabetic nephropathy (DN) and triglyceride/glucose (TyG) index and triglyceride/high-density lipoprotein cholesterol ratio (Tg/HDL-C) as surrogate markers of insulin resistan...
Background/Objectives: The global increase in metabolic dysfunction-associated steatotic liver disease underscores the need for accessible and reliable markers to assess hepatic steatosis. The triglyceride–glucose (TyG) index, derived from fast...
Background: Insulin resistance (IR) has been implicated in cardiovascular diseases, and a correlation between IR and the slow flow phenomenon (CSF)has been identified. The triglyceride–glucose index (TGI), a simple surrogate marker for IR, has...
Background/Objectives: Insulin resistance is crucial in the pathogenesis of Metabolic Syndrome (MetS), type 2 diabetes mellitus (T2DM) and premature atherosclerotic cardiovascular disease (ASCVD). The triglyceride–glucose index (TyG index), a v...
The aim of this study was to investigate the associations between the triglyceride-glucose (TyG) index, a marker of insulin resistance, and microangiopathies and macroangiopathies in patients with type 2 diabetes mellitus (DM). Our study enrolled 199...
Background: The triglyceride–glucose (TyG) index, a surrogate marker of insulin resistance, has been increasingly associated with adverse cardiometabolic outcomes. However, its relationship with acute kidney injury (AKI) across clinical setting...
Background and Aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) is increasingly prevalent and linked to liver and cardiometabolic complications. Although liver biopsy remains the diagnostic gold standard, its invasiveness limits rou...
Background/Objectives: The triglyceride–glucose (TyG) index, a reliable marker for insulin resistance, is strongly associated with T2DM, hypertension, and cardiovascular disease. Less well known is its relationship with cancer risk. The aim of...
Objective: To explore the association of diabetic retinopathy (DR) with TyG index and TyG-related parameters among the United States population. Methods: This cross-sectional study is conducted in adults with diabetes mellitus based on the National H...
Background: To examine the effect of the triglyceride-glucose (TyG) index on longitudinal cognitive decline in a healthy middle-aged-to-elderly population. Methods: We conducted a population-based longitudinal study. A total of 1774 participants with...
Background: The triglyceride-glucose (TyG) index is a novel biomarker of insulin resistance which might plausibly influence endogenous fibrinolysis and thus early neurological outcomes in patients with acute ischemic stroke (AIS) treated with intrave...
Background/Objectives: The objective of this study was to assess the diagnostic accuracy of the Triglyceride-Glucose (TyG) index for screening gestational diabetes mellitus (GDM) at 24–28 weeks of gestation, to determine its optimal diagnostic...
Ageing is associated with increasing metabolic heterogeneity driven by interactions between adipose tissue dysfunction and altered glucose-lipid metabolism. The vitamin D receptor (VDR) rs7975232 polymorphism has been investigated in relation to meta...
Background/Objectives: Low-grade chronic inflammation is recognized as part of the systemic profile of polyendocrine metabolic ovarian syndrome (PMOS, formerly polycystic ovary syndrome, PCOS), although whether this inflammatory signal tracks insulin...
Background/Objectives: Insulin resistance during pregnancy is a key factor underlying gestational diabetes mellitus (GDM) and other adverse perinatal outcomes (APOs). While traditional markers, such as HOMA-IR, are used to evaluate insulin resistance...
Background: Type 2 diabetes mellitus (T2DM) is a major contributor to cardiovascular disease worldwide, with insulin resistance (IR) being a central pathophysiological mechanism. The triglyceride–glucose (TyG) index, derived from routine fastin...
Objective: This study aimed to evaluate the association between the triglyceride–glucose index (TGI) and the risk of cardiovascular disease in patients with type 2 diabetes mellitus. Methods: This study included 1348 type 2 diabetic patients wh...
Atrial fibrillation (AF) is the most common arrhythmia worldwide, a major cause of heart failure and stroke, and carries a significant healthcare burden. Atrial cardiomyopathy (ACM) provides the structural and electrophysiological basis for AF, while...
(1) Background: Dyslipidaemia and insulin resistance are major risk factors for coronary artery disease (CAD). This study investigated the relationship between plasma atherogenic index (PA-I), triglyceride-glucose index (TGI) and other lipid ratios w...
This study aimed to explore the potential association between the triglyceride–glucose index (TyG) and the atherogenic index of plasma (AIP)—both considered surrogate markers for atherosclerosis—and major adverse cardiovascular even...
1 November 2026
Background: Metabolic dysregulation substantially contributes to adverse outcomes in acute myocardial infarction (AMI). While the triglyceride–glucose (TyG) index reflects chronic insulin resistance, the stress hyperglycemia ratio (SHR) represe...
Background/Objectives: This study aimed to investigate the prognostic significance of the triglyceride–glucose index (TGI), triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, and inflammatory biomarkers in predicting short-t...
Insulin resistance (IR) is a major contributor to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). The triglyceride-glucose (TyG) index has recently gained popularity for the assessment of IR and NAFLD due to its ease of acquisition and...
Objectives: We aimed to evaluate the predictive importance of various clinical and laboratory parameters in the differential diagnosis of Acute Coronary Syndrome (ACS). Understanding these predictors is critical for improving diagnostic accuracy, gui...
Background/Objectives: Recent studies have highlighted the Triglyceride–Glucose Index (TYG) as a significant risk factor for mortality and co-morbidities in various populations, including those with type 2 diabetes mellitus (T2DM) and cardiovas...
Objectives: This study aimed to investigate the relationship between the triglyceride–glucose (TyG) index, its combination with the body roundness index (BRI), and chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM) ba...
Background/Objectives: We examined correlates of lumbar–femoral T-score differences (ΔT), retaining the triglyceride–glucose (TyG) index as the prespecified primary exposure. Methods: This retrospective cross-sectional analysis of r...
Background/Objectives: Coronary slow flow phenomenon (CSFP) is considered a condition identified during coronary angiography (CAG), associated with recurrent ischemic symptoms and adverse cardiovascular outcomes while no significant epicardial corona...
Contrast-associated acute kidney injury (CA-AKI) is an important complication of renal angiography in patients with atherosclerotic renal artery stenosis (RAS). We investigated the associations of the triglyceride–glucose (TyG) index, atherogen...
Background and Objectives: There are few studies suggesting that the Triglyceride–Glucose Index (TyG), which is mostly defined as a predictor of diabetes, can be used as a predictor of coronary artery disease. In this study, we investigated the...
Background/Objectives: Insulin resistance is increasingly recognized as a cause of colorectal neoplasms, but its measurement requires fasting insulin, which is not routinely available in clinical settings. The triglyceride–glucose (TyG) index,...
Background: The triglyceride–glucose (TyG) index is a simple surrogate marker of insulin resistance (IR) and has been associated with coronary artery disease (CAD). However, the association between the TyG index and coronary chronic total occlu...
Background/Objectives: Evidence regarding the triglyceride–glucose (TyG) index and premature myocardial infarction (MI) in non-diabetic adults remains limited. We evaluated whether pre-event TyG values were associated with premature MI in a pro...
Background: The triglyceride-glucose (TyG) index is a new alternative insulin resistance (IR) biomarker. The purpose of this study was to assess whether the TyG index can have a prognostic value in patients with acute coronary syndrome (ACS). Moreove...
Background: Atrial fibrillation (AF) is a major substrate for ischemic stroke, but cerebrovascular risk is heterogeneous and influenced by AF phenotype, comorbidities, anticoagulant exposure, renal function, and metabolic risk. The triglyceride&ndash...
Background: The triglyceride–glucose (TyG) index has emerged as a simple surrogate marker of insulin resistance and metabolic disruption. In the context of ST-elevation myocardial infarction (STEMI), such disturbances have been associated with...
Background: Premature coronary artery disease (PCAD) represents a growing clinical concern. Although insulin resistance is central to atherogenesis and the triglyceride–glucose (TyG) index serves as a practical surrogate for insulin resistance,...
This study aimed to evaluate the association between the triglyceride–glucose index (TyG) and the risk of diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus. Methods: This study included 1347 patients with type 2 diabetes w...
Purpose: Studies suggest that the triglyceride–glucose index (TyG) is a novel and comprehensive marker of metabolic health. While most research indicates that increased physical activity (PA) is linked to improved metabolic health, some studies...
Background/Objectives: The triglyceride–glucose index (TyG) and conicity index (CI) are markers of insulin resistance and abdominal obesity, respectively. However, their joint impact on stroke remains unclear. This study aimed to assess the ass...
Background and Objectives: The triglyceride–glucose (TyG) index is an accessible surrogate marker of insulin resistance and has been increasingly investigated for its prognostic relevance in cardiovascular disease. However, evidence regarding i...
Background/Objective: Type 2 diabetes mellitus (T2DM) is a known risk factor for cardiovascular disease (CVD); however, not all individuals with T2DM have the same CVD risk. Traditional glycemic cluster analyses of individuals with diabetes using the...
Objectives: We aimed to evaluate the importance of metabolic and inflammatory markers, specifically the Triglyceride–Glucose Index (TGI) and pan-immune inflammation value (PIV), in predicting mortality among patients diagnosed with pulmonary th...
Objective: This study aimed to evaluate the prognostic value of changes in the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), Visceral Adiposity Index (VAI), and Triglyceride-Glucose (TyG) index in predicting type 2 diabetes mellitus (...
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