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350 Results Found

  • Review
  • Open Access
79 Citations
6,990 Views
18 Pages

Food additive zinc oxide (ZnO) nanoparticles (NPs) are widely used as a Zn supplement in the food and agriculture industries. However, ZnO NPs are directly added to complex food-matrices and orally taken through the gastrointestinal (GI) tract where...

  • Review
  • Open Access
24 Citations
5,669 Views
16 Pages

26 December 2022

The genotoxicity, mutagenesis, and carcinogenic effects of polycyclic aromatic hydrocarbon (PAH) derivatives may exceed the parent PAHs. However, their influence on the soil environment has not been explored to a large extent. Oxygenated polycyclic a...

  • Article
  • Open Access
2 Citations
605 Views
23 Pages

11 October 2025

Unsymmetrical dimethylhydrazine (1,1-Dimethylhydrazine, UDMH) is widely used as a high-performance liquid rocket propellant for the space industry globally. The release and leakage of UDMH into the environment, especially the soil environment, pose s...

  • Review
  • Open Access
40 Citations
7,189 Views
24 Pages

29 August 2022

Recently, there has been rapid growth in the production of zinc oxide nanoparticles (ZnO-NPs) due to their applications in household and cosmetic products. Over the last decade, considerable research was conducted to reveal the effect of ZnO-NPs on m...

  • Review
  • Open Access
103 Citations
5,327 Views
47 Pages

Safety Evaluation of Nanotechnology Products

  • Abraham J. Domb,
  • Ghorbanali Sharifzadeh,
  • Victoria Nahum and
  • Hossein Hosseinkhani

Nanomaterials are now being used in a wide variety of biomedical applications. Medical and health-related issues, however, have raised major concerns, in view of the potential risks of these materials against tissue, cells, and/or organs and these ar...

  • Review
  • Open Access
23 Citations
11,137 Views
32 Pages

Micro- and Nano-Plastics Contaminants in the Environment: Sources, Fate, Toxicity, Detection, Remediation, and Sustainable Perspectives

  • Abdulkarim Hasan Rashed,
  • Gamze Yesilay,
  • Layla Hazeem,
  • Suad Rashdan,
  • Reem AlMealla,
  • Zeynep Kilinc,
  • Fatema Ali,
  • Fatima Abdulrasool and
  • Ayman H. Kamel

11 October 2023

The continuous production and widespread applications of synthetic plastics and their waste present immense environmental challenges and damage living systems. Microplastics (MPs) have become of great concern in various ecosystems due to their high s...

  • Article
  • Open Access
7 Citations
3,673 Views
18 Pages

(1) Background: Synthetic amorphous silica (SAS) is widely used as a food additive and contains nano-sized particles. SAS can be produced by fumed and precipitated methods, which may possess different physiochemical properties, toxicokinetics, and or...

  • Article
  • Open Access
26 Citations
3,298 Views
20 Pages

8 February 2021

Zinc oxide (ZnO) particles have been used as dietary supplements because zinc is an essential trace element for humans. Along with the rapid development of nanotechnology, the use of ZnO nanoparticles (NPs) is increasing in the food industry, but the...

  • Concept Paper
  • Open Access
2 Citations
1,945 Views
14 Pages

19 March 2023

Ensuring for the national defense requires the use of substances such as energetics, propellants, pyrotechnics, and other materials in environmental applications. Systems that use these materials do so in testing and training environments and must be...

  • Review
  • Open Access
47 Citations
6,772 Views
29 Pages

Do Microplastics and Nanoplastics Pose Risks to Biota in Agricultural Ecosystems?

  • Naga Raju Maddela,
  • Balasubramanian Ramakrishnan,
  • Tanvi Kadiyala,
  • Kadiyala Venkateswarlu and
  • Mallavarapu Megharaj

The presence of microplastics and nanoplastics (MNPs) in soils is becoming pervasive in most agroecosystems. The recent estimates suggest that the soil burden of MNPs in the agroecosystems is more than 0.5 megatons (Mt) annually. In all the agroecosy...

  • Review
  • Open Access
1,299 Views
25 Pages

30 November 2025

The pervasive environmental contamination by microplastics (MPs) and per- and polyfluoroalkyl substances (PFAS) represents a critical challenge of the Anthropocene. While historically studied in isolation, a growing body of evidence confirms that the...

  • Review
  • Open Access
4 Citations
1,832 Views
23 Pages

Nanomaterials for Persistent Organic Pollutants Decontamination in Water: Mechanisms, Challenges, and Future Perspectives

  • Risky Ayu Kristanti,
  • Tony Hadibarata,
  • Adelina-Gabriela Niculescu,
  • Dan Eduard Mihaiescu and
  • Alexandru Mihai Grumezescu

21 July 2025

Nanomaterials possess unique physicochemical properties that position them as promising candidates for environmental remediation, particularly in the removal of persistent organic pollutants (POPs) from aqueous systems. Their high surface area, tunab...

  • Feature Paper
  • Review
  • Open Access
58 Citations
13,150 Views
19 Pages

Environmental Fate and Toxicity of Sunscreen-Derived Inorganic Ultraviolet Filters in Aquatic Environments: A Review

  • Shengwu Yuan,
  • Jingying Huang,
  • Xia Jiang,
  • Yuxiong Huang,
  • Xiaoshan Zhu and
  • Zhonghua Cai

19 February 2022

An increasing number of inorganic ultraviolet filters (UVFs), such as nanosized zinc oxide (nZnO) and titanium dioxide (nTiO2), are formulated in sunscreens because of their broad UV spectrum sunlight protection and because they limit skin damage. Ho...

  • Article
  • Open Access
26 Citations
3,767 Views
17 Pages

16 April 2021

Silver nanoparticles (AgNPs) are favoured antibacterial agents in nano-enabled products and can be released into water resources where they potentially elicit adverse effects. Herein, interactions of 10 and 40 nm AgNPs (10-AgNPs and 40-AgNPs) with aq...

  • Article
  • Open Access
9 Citations
2,681 Views
25 Pages

Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells

  • Caroline Bissardon,
  • Olivier Proux,
  • Salvatore Andrea Gazze,
  • Odile Filhol,
  • Benoît Toubhans,
  • Lucie Sauzéat,
  • Sylvain Bouchet,
  • Aled R. Lewis,
  • Thierry Maffeis and
  • Sylvain Bohic
  • + 5 authors

22 November 2023

Selenium 0 (Se0) is a powerful anti-proliferative agent in cancer research. We investigated the impact of sub-toxic concentrations of Se0 functionalized nanoparticles (SeNPs) on prostate cancer PC-3 cells and determined their intracellular localizati...

  • Article
  • Open Access
4 Citations
2,606 Views
22 Pages

10 November 2022

The potential environmental impact of historical mining and ore processing on stream sediments and water was studied in a small siderite iron ore deposit with diverse sulfide mineral paragenesis. The main aim was to characterize solid carriers of pot...

  • Review
  • Open Access
7 Citations
4,674 Views
25 Pages

Illicit Drugs in Surface Waters: How to Get Fish off the Addictive Hook

  • Halina Falfushynska,
  • Piotr Rychter,
  • Anastasiia Boshtova,
  • Yuliia Faidiuk,
  • Nadiia Kasianchuk and
  • Piotr Rzymski

22 April 2024

The United Nations World Drug Report published in 2022 alarmed that the global market of illicit drugs is steadily expanding in space and scale. Substances of abuse are usually perceived in the light of threats to human health and public security, wh...

  • Review
  • Open Access
343 Citations
22,265 Views
26 Pages

Cerium is the most abundant of rare-earth metals found in the Earth’s crust. Several Ce-carbonate, -phosphate, -silicate, and -(hydr)oxide minerals have been historically mined and processed for pharmaceutical uses and industrial applications. Of all...

  • Review
  • Open Access
31 Citations
4,199 Views
13 Pages

Occurrence, Fate, and Implications of Heavy Metals during Anaerobic Digestion: A Review

  • Rahul Kadam,
  • Kamonwan Khanthong,
  • Heewon Jang,
  • Jonghwa Lee and
  • Jungyu Park

17 November 2022

Over the years, anaerobic digestion (AD) has evolved as a competent technology to retrieve energy potential from various organic substrates, including wastewater. However, the energy metabolisms of anaerobic microorganisms, biochemical reactions, and...

  • Review
  • Open Access
164 Citations
17,477 Views
18 Pages

Herbicide Glyphosate: Toxicity and Microbial Degradation

  • Simranjeet Singh,
  • Vijay Kumar,
  • Jatinder Pal Kaur Gill,
  • Shivika Datta,
  • Satyender Singh,
  • Vaishali Dhaka,
  • Dhriti Kapoor,
  • Abdul Basit Wani,
  • Daljeet Singh Dhanjal and
  • Joginder Singh
  • + 2 authors

Glyphosate is a non-specific organophosphate pesticide, which finds widespread application in shielding crops against the weeds. Its high solubility in hydrophilic solvents, especially water and high mobility allows the rapid leaching of the glyphosa...

  • Review
  • Open Access
72 Citations
11,773 Views
21 Pages

Microplastics, a Global Issue: Human Exposure through Environmental and Dietary Sources

  • Lucrezia Borriello,
  • Marcello Scivicco,
  • Nunzio Antonio Cacciola,
  • Francesco Esposito,
  • Lorella Severino and
  • Teresa Cirillo

11 September 2023

Plastic production has grown dramatically over the years. Microplastics (MPs) are formed from the fragmentation of larger plastic debris by combining chemical, physical, and biological processes and can degrade further to form nanoplastics (NPs). Bec...

  • Article
  • Open Access
2 Citations
2,169 Views
17 Pages

Aquatic Fate and Ecotoxicology Effect of ZnS:Mn Quantum Dots on Chlorella vulgaris in Fresh Water

  • Bingbing Deng,
  • Rania Maaloul,
  • Sophie Nowak,
  • Yann Sivry,
  • Claude Yéprémian,
  • Souad Ammar,
  • Fayna Mammeri and
  • Roberta Brayner

26 March 2024

With the increasing integration of nanomaterials into daily life, the potential ecotoxicological impacts of nanoparticles (NPs) have attracted increased attention from the scientific community. This study assessed the ecotoxicity of ZnS quantum dots...

  • Review
  • Open Access
19 Citations
8,301 Views
25 Pages

7 December 2024

Pesticides are inevitable agrochemicals employed as plant protection agents and their application follows good agricultural practice (GAP). Although pesticides are primarily used for plant protection purposes, the residual pesticides may pose a threa...

  • Review
  • Open Access
24 Citations
12,037 Views
27 Pages

21 June 2021

Recently, microplastics pollution has attracted much attention in the environmental field, as researchers have found traces of microplastics in both marine and terrestrial ecological environments. Here, we reviewed and discussed the current progress...

  • Article
  • Open Access
524 Views
25 Pages

Delivery and Metabolic Fate of Doxorubicin and Betulin Nanoformulations In Vivo: A Metabolomics Approach

  • Mihai Adrian Socaciu,
  • Remus Moldovan,
  • Carmen Socaciu,
  • Flaviu Alexandru Tăbăran and
  • Simona Clichici

5 November 2025

Background: Betulins (betulin, betulinic acid and lupeol) demonstrated antitumor and chemopreventive activity but showed low bioavailability due to their self-aggregation in hydrophilic environments. To overcome these disadvantages, their incorporati...

  • Article
  • Open Access
38 Citations
4,183 Views
17 Pages

(1) Background: Zinc oxide (ZnO) particles are widely used as zinc (Zn) fortifiers, because Zn is essential for various cellular functions. Nanotechnology developments may lead to production of nano-sized ZnO, although nanoparticles (NPs) are not int...

  • Article
  • Open Access
1,105 Views
24 Pages

PLA Nanoplastics Accumulate but Do Not Cause Acute Toxicity to Marine Rotifers, Brine Shrimps, and Zebrafish Embryos

  • Doyinsola Suliat Mustapha,
  • Olga Rodríguez-Díaz,
  • Miren P. Cajaraville and
  • Amaia Orbea

12 November 2025

Conventional plastics are widely utilised across industrial sectors and in consumer products. However, the growing use of plastics has led to plastic pollution, including the formation of nanoplastics (NPs), which are harmful to aquatic organisms. Bi...

  • Abstract
  • Open Access
1,112 Views
2 Pages

Opposite to the significant knowledge about the toxicity of AgNPs to phytoplankton species, rather limited knowledge is available about the role of phytoplankton secretions such as extracellular polymer substances (EPS) in NPs’ fate [...]

  • Article
  • Open Access
10 Citations
6,196 Views
15 Pages

A microcosm designed for culturing aquatic phototrophic biofilms on artificial substrata was used to perform experiments with microphytobenthos sampled during summer toxic outbreaks of Ostreopsis cf. ovata along the Middle Tyrrhenian coast. This dyna...

  • Perspective
  • Open Access
352 Views
14 Pages

15 December 2025

The widespread use of anticancer drugs (ACDs) in human therapies determines the occurrence of these potent cytotoxic chemicals into aquatic ecosystems. Nowadays, ACDs are ubiquitous contaminants in wastewater effluents and freshwater compartments, ra...

  • Review
  • Open Access
67 Citations
10,317 Views
24 Pages

Origin and Fate of Acrolein in Foods

  • Kaiyu Jiang,
  • Caihuan Huang,
  • Fu Liu,
  • Jie Zheng,
  • Juanying Ou,
  • Danyue Zhao and
  • Shiyi Ou

3 July 2022

Acrolein is a highly toxic agent that may promote the occurrence and development of various diseases. Acrolein is pervasive in all kinds of foods, and dietary intake is one of the main routes of human exposure to acrolein. Considering that acrolein i...

  • Article
  • Open Access
2 Citations
2,479 Views
22 Pages

Sediments of Hydropower Plant Water Reservoirs Contaminated with Potentially Toxic Elements as Indicators of Environmental Risk for River Basins

  • João Batista Pereira Cabral,
  • Wanderlubio Barbosa Gentil,
  • Fernanda Luisa Ramalho,
  • Assunção Andrade de Barcelos,
  • Valter Antonio Becegato and
  • Alexandre Tadeu Paulino

26 September 2024

The aim of this work was to determine the concentrations, distribution, and fate of potentially toxic elements [lead (Pb), zinc (Zn), nickel (Ni), copper (Cu), mercury (Hg), arsenic (As), and cadmium (Cd)] in sediments of a hydropower plant water res...

  • Article
  • Open Access
13 Citations
5,842 Views
14 Pages

A Novel Experimental and Modelling Strategy for Nanoparticle Toxicity Testing Enabling the Use of Small Quantities

  • Marinda Van Pomeren,
  • Willie J. G. M. Peijnenburg,
  • Nadja R. Brun and
  • Martina G. Vijver

Metallic nanoparticles (NPs) differ from other metal forms with respect to their large surface to volume ratio and subsequent inherent reactivity. Each new modification to a nanoparticle alters the surface to volume ratio, fate and subsequently the t...

  • Editorial
  • Open Access
1,190 Views
3 Pages

6 September 2023

The occurrence of potentially toxic elements (PTEs, including As, Cd, Hg and Pb) of both anthropogenic and natural origin in the environment represents an issue of global concern, leading to a general decline in environmental quality in both continen...

  • Review
  • Open Access
42 Citations
5,425 Views
19 Pages

27 March 2022

Inorganic or organic nanoparticles are often incorporated into foods to enhance their quality, stability, nutrition, or safety. When they pass through the gastrointestinal environment, the properties of these nanoparticles are altered, which impacts...

  • Article
  • Open Access
5 Citations
3,381 Views
21 Pages

28 January 2024

A food additive, silicon dioxide (SiO2) is commonly used in the food industry as an anti-caking agent. The presence of nanoparticles (NPs) in commercial food-grade SiO2 has raised concerns regarding their potential toxicity related to nano size. Whil...

  • Review
  • Open Access
3 Citations
2,328 Views
22 Pages

26 May 2025

Per- and polyfluoroalkyl substances (PFAS) are used in consumer products and manufacturing. Perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), and perfluoroundecanoic acid (PFUnDA) are long-chain PFAS composed of 9, 10, and 11 carbons, res...

  • Article
  • Open Access
19 Citations
4,757 Views
19 Pages

Food additive amorphous silicon dioxide (SiO2) particles are manufactured by two different methods—precipitated and fumed procedures—which can induce different physicochemical properties and biological fates. In this study, precipitated and fumed SiO...

  • Review
  • Open Access
75 Citations
13,133 Views
24 Pages

Microplastics in the Aquatic Environment—The Occurrence, Sources, Ecological Impacts, Fate, and Remediation Challenges

  • Nhamo Chaukura,
  • Kebede K. Kefeni,
  • Innocent Chikurunhe,
  • Isaac Nyambiya,
  • Willis Gwenzi,
  • Welldone Moyo,
  • Thabo T. I. Nkambule,
  • Bhekie B. Mamba and
  • Francis O. Abulude

18 June 2021

Microplastics are discharged into the environment through human activities and are persistent in the environment. With the prevalent use of plastic-based personal protective equipment in the prevention of the spread of the COVID-19 virus, the concent...

  • Viewpoint
  • Open Access
3 Citations
3,449 Views
4 Pages

A Framework for Ecotoxicity Testing in the 21st Century: Ecotox21

  • Zhen-guang Yan,
  • Xin Zheng,
  • Fu Gao,
  • Jun-tao Fan,
  • Shu-ping Wang and
  • Li-xin Yang

28 January 2019

To reduce the considerable investments of toxicity testing and protecting animal welfare, a new toxicity testing strategy based on response pathways of human cell lines has been proposed in the United States to evaluate the chemical exposure risks to...

  • Review
  • Open Access
82 Citations
12,067 Views
21 Pages

Wine Contamination with Ochratoxins: A Review

  • Jessica Gil-Serna,
  • Covadonga Vázquez,
  • María Teresa González-Jaén and
  • Belén Patiño

Ochratoxin A (OTA) is the main mycotoxin occurring in wine. This review article is focused on the distribution of this toxin and its producing-fungi in grape berries, as well as on the fate of OTA during winemaking procedures. Due to its toxic proper...

  • Article
  • Open Access
46 Citations
8,895 Views
13 Pages

27 June 2014

Cu is an essential trace element but can be highly toxic to aquatic organisms at elevated concentrations. Greater use of CuO engineered nanoparticles (ENPs) may lead to increased concentrations of CuO ENPs in aquatic environments causing potential ec...

  • Article
  • Open Access
12 Citations
6,770 Views
27 Pages

Daily Freeze–Thaw Cycles Affect the Transport of Metals in Streams Affected by Acid Drainage

  • Paula Guerra,
  • Kyle Simonson,
  • Christian González,
  • Jorge Gironás,
  • Cristian Escauriaza,
  • Gonzalo Pizarro,
  • Carlos Bonilla and
  • Pablo Pasten

26 February 2016

Stream flow rates with seasonal, daily, or hourly cycles due to freezing and thawing can control downstream chemical processes by changing the mixing ratio of reactive flows. The extent of these hydrologic-chemical interactions has not been fully rea...

  • Article
  • Open Access
10 Citations
2,678 Views
16 Pages

Wastewater treatment plants (WWTP) are regarded as the last barriers for the release of incompletely separated and recycled nanoparticles (NPs) into the environment. Despite the importance and ubiquity of microbial extracellular polymeric substances...

  • Review
  • Open Access
38 Citations
6,193 Views
17 Pages

Degradation of Triclosan in the Water Environment by Microorganisms: A Review

  • Yiran Yin,
  • Hao Wu,
  • Zhenghai Jiang,
  • Jingwei Jiang and
  • Zhenmei Lu

Triclosan (TCS), a kind of pharmaceuticals and personal care products (PPCPs), is widely used and has had a large production over years. It is an emerging pollutant in the water environment that has attracted global attention due to its toxic effects...

  • Editorial
  • Open Access
1 Citations
4,746 Views
1 Page

Introducing Toxics

  • David C. Bellinger

11 April 2013

With this inaugural issue, Toxics begins its life as a peer-reviewed, open access journal focusing on all aspects of toxic chemicals. We are interested in publishing papers that present a wide range of perspectives on toxicants and naturally occurrin...

  • Article
  • Open Access
10 Citations
3,843 Views
12 Pages

Toxic Metals and Metalloids in Hassawi Brown Rice: Fate during Cooking and Associated Health Risks

  • Abdulaziz Abdulrahman AlMulla,
  • Saad Dahlawi,
  • Muhammad Atif Randhawa,
  • Qamar uz Zaman,
  • Yinglong Chen and
  • Turki Kh. Faraj

Rice has been a dietary staple for centuries, providing vital nutrients to the human body. Brown rice is well known for its nutrient-dense food profile. However, owing to multiple causes (anthropogenic and non-anthropogenic), it can also be a potenti...

  • Article
  • Open Access
22 Citations
4,149 Views
19 Pages

Intracellular Fate and Impact on Gene Expression of Doxorubicin/Cyclodextrin-Graphene Nanomaterials at Sub-Toxic Concentration

  • Daniela Caccamo,
  • Monica Currò,
  • Riccardo Ientile,
  • Elisabetta AM Verderio,
  • Angela Scala,
  • Antonino Mazzaglia,
  • Rosamaria Pennisi,
  • Maria Musarra-Pizzo,
  • Roberto Zagami and
  • Maria Teresa Sciortino
  • + 6 authors

The graphene road in nanomedicine still seems very long and winding because the current knowledge about graphene/cell interactions and the safety issues are not yet sufficiently clarified. Specifically, the impact of graphene exposure on gene express...

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