16,887 Results Found

Reservoir water level regulation induces intricate processes of phosphorus (P) migration and release within the water-level fluctuation zone (WLFZ). These dynamic interactions pose significant challenges for effective pollution management strategies....

The release of available potential energy by growing baroclinic instability requires the slope of the eddy fluxes to be shallower than that of mean density surfaces, where the amount of energy released depends on both the flux angle and the distance...

Objective. The aim of this study was to investigate the effects of bupropion sustained release (SR) on cognitive function, evaluated by event-related potentials (ERPs), in heavy tobacco smokers.

Material and Methods. A total of 10 healthy volunteers...

Reservoir sediments act as important receivers and sources for nutrients in the overlaying water. To determine the sediments adsorption and release characteristics and their impacts on water quality, surface sediments samples collected from Biliuhe r...

Abandoned, lost, or discarded fishing gear (ALDFG) poses significant environmental threats, namely contributing to microplastic (MP) pollution. However, the release of MPs from ALDFG remains poorly studied, despite its crucial role in understanding p...

Natural silk protein nanoparticles are a promising biomaterial for drug delivery due to their pleiotropic properties, including biocompatibility, high bioavailability, and biodegradability. Chinese oak tasar Antheraea pernyi silk fibroin (ApF) nanopa...

Mercaptopurine is one of the drugs used in the treatment of acute lymphoblastic leukemia. A problem with mercaptopurine therapy is its low bioavailability. This problem can be solved by preparing the carrier that releases the drug in lower doses but...

Skin diseases such as atopic dermatitis (AD) are widespread and affect people all over the world. Current treatments for dry and itchy skin are mostly focused on pharmaceutical solutions, while supportive therapies such as ointments bring immediate r...

Naturally occurring asbestos (NOA) represents a matter of social and environmental concern due to its potential release in the atmosphere during rock excavation and grinding in quarry and road tunnel activities. In most cases, NOA occurs in serpentin...

Sugarcane bagasse-derived biochars, produced at 350 °C (B350) and 600 °C (B600), were evaluated for their capacity to modify the sorption behavior of the herbicide sulfentrazone (SFZ) in Red–Yellow Latosol (RYL) and to serve as carriers...

The major part of iron present in plant foods such as cereals is largely unavailable for direct absorption in humans due to complexation with the negatively charged phosphate groups of phytate (myo-inositol (1,2,3,4,5,6)-hexakisphosphate). Human bio...

Within the context of sustainable exploitation of phytogenetic resources, the present study aimed to develop species-specific seed germination protocols for eighteen native and potentially underutilized plant species originating from northeastern Gre...

Implant surface characteristics, as well as physical and mechanical properties, are responsible for the positive interaction between the dental implant, the bone and the surrounding soft tissues. Unfortunately, the dental implant surface does not rem...

Water scarcity and the loss of fertilizer from agricultural soils through runoff, which also leads to contamination of other areas, are increasingly common problems in agriculture. To mitigate nitrate water pollution, the technology of controlled rel...

The problem of drug delivery often concentrates on the prolongation of drug activity. Application of natural polymers which are biodegradable and inexpensive is in the interest of many researchers. The aim of this study was the application of newly s...

End-of-life tyre (ELT) management is still a hot topic due to implications for sustainability and human health. This review aims to summarise the findings concerning the chemicals’ bio-accessibility/availability from the granular tyre-derived i...

Background/Objectives: Improving the production rates of modern tablet presses places ever greater demands on the performance of excipients. Although co-processing has emerged as a promising solution, there is still a lack of directly compressible ex...

Despite many available approaches for transdermal drug delivery, patient compliance and drug targeting at the desired concentration are still concerns for effective therapies. Precise and efficient film-forming systems provide great potential for con...

Human activities lead to an increase in greenhouse gases in the environment, among which carbon dioxide (CO₂) is one of the most prominent, giving rise to global warming and climate change. Climate change, along with the resulting environmental degra...

The grasslands of Inner Mongolia are prone to wildfires, which can endanger the grassland ecosystem, as well as people’s lives and property. The amount of heat released by grassland fires must be determined for the quantitative evaluation of gr...

Cardiac calcium alternans is defined as beat-to-beat alternations of Ca transient (CaT) amplitude and has been linked to cardiac arrhythmia, including atrial fibrillation. We investigated the mechanism of atrial alternans in isolated rabbit atrial my...

Drug-delivery vehicles have been used extensively to modulate the biodistribution of drugs for the purpose of maximizing their therapeutic effects while minimizing systemic toxicity. The release characteristics of the vehicle must be balanced with it...

Feather keratin (FK) extracted from feathers represents a valuable source of biodegradable and biocompatible polymer. The aim of this study was the development and characterization of blended films based on FK and polyvinyl alcohol (PVA) cross-linked...

In this study, bovine serum albumin (BSA) and alginate (ALG) conjugates were synthesized by the Maillard reaction in order to evaluate their potential to develop controlled release drug delivery systems. The progress of the Maillard reaction was evid...

Nonferrous smelting is an important source of heavy metals in soil, which causes different degrees of soil pollution, especially in lead–zinc (Pb/Zn) smelting areas. Based on the Pb/Zn environmental release during the Pb/Zn mineral smelting pro...

The renin–angiotensin system (RAS) and hypoxia have a complex interaction: RAS is activated under hypoxia and activated RAS aggravates hypoxia in reverse. Renin is an aspartyl protease that catalyzes the first step of RAS and tightly regulates...

Today, laws protecting the population at the global level aim to minimize the induction risk of allergies to type IV contact dermatitis. In the European population, the prevalence of nickel allergy is at 10%–15% of adult females and 1%–3%...

This study aimed to develop a prolonged-release device for the potential site-specific delivery of a neuroprotective agent (nicotine). The device was formulated as a novel reinforced crosslinked composite polymeric system with the potential for intra...

Bottom ash is the major by-product of waste incineration and can contain trace elements (As, Cd, Co, Cu, Cr, Mo, Ni, Pb, and Zn) with concentrations up to thousands of mg·k⁻¹. In this study, a combination of different extractions and lea...

Current routine high-sensitivity cardiac troponin assays are the criterion standard for the laboratory diagnosis of myocardial injury due to their high analytical sensitivity and specificity. However, in daily clinical practice, unexpectedly elevated...

This article describes the synthesis and characterization of β-cyclodextrin-based nano-sponges (NS) inclusion compounds (IC) with the anti-tumor drugs melphalan (MPH) and cytoxan (CYT), and the addition of gold nanoparticles (AuNPs) onto both systems...

The nanoencapsulation of bioactive compounds such as β-carotene and microalgal extracts has emerged as an effective strategy to enhance their stability, bioavailability, and biological efficacy, particularly against oxidative stress. Dunaliella ...

Phenolipids such as alkyl gallates (A-GAs) have been approved by the food industry as non-toxic antioxidant additives, which are also regarded as an emerging source of functional food ingredients. However, comprehensive understanding of their digesti...

The centralized Rio Seco Industrial Park (RSIP) tannery collective in the Southern Peruvian city of Arequipa releases untreated tannery wastewater into a proximal creek that is a tributary of the Chili River. As industrial leather tanning wastewater...

Hyaluronic acid, a biocompatible polymer, holds significant potential for drug delivery applications. Its variable degree of protonation, which entails tunable physical properties, makes it an ideal candidate for developing pH-sensitive hydrogels. Li...

This study describes the behavior of potential slow-release fertilizers (SRF), prepared by the mechanochemical activation of calcined Mg₂Al-CO₃ or Mg₂Fe-CO₃ layered double hydroxides (LDH) mixed with dipotassium hydrogen phosphate (K₂HPO₄). The effec...

In recent years, polymeric materials have been gaining prominence in studies of controlled release systems to obtain improvements in drug administration. These systems present several advantages compared with conventional release systems, such as con...

Archaeosomes have drawn increasing attention in recent years as novel nano-carriers for therapeutics. The main obstacle of using archaeosomes for therapeutics delivery has been the lack of an efficient method to trigger the release of entrapped conte...

Thymoquinone (TQ), a natural polyphenol, has been associated with various pharmacological responses; however, low bioavailability of TQ limits its clinical application. Thus, a novel phytosomal delivery system of TQ-Phospholipon^® 90H complex (TQ-phyt...

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an unmet need of biomarkers that can aid in the diagnostic and prognostic assessment of the disease and response to treatment. In this two-part explorative proteomic stud...

In the realm of building demolition, ensuring the uniform distribution of energy from multiple sources is of paramount significance for the systematic deconstruction of large structures. This study presents an integrated methodology that combines gen...

Boron neutron capture therapy (BNCT) is a non-invasive therapeutic technique for treating malignant tumors, however, methods to evaluate its therapeutic efficacy and adverse reactions are lacking. High mobility group box 1 (HMGB1) is an inflammatory...

In this study, we examined a possible use of a surface-deacetylated chitin nano-fiber (SDCH-NF) and hyaluronic acid (HA) interpolymer complex (IPC) tablet as a potential antioxidative compound in extended-release matrix tablets. The antioxidant prope...

Phosphate has been proven to be effective in remediating soils contaminated with potentially toxic elements (PTEs); however, the potential release of phosphorus (P) through runoff and the impact on PTEs’ transport in this process have never bee...

Background/Objectives: Pneumocystis jirovecii pneumonia (PJP) is the most frequently diagnosed AIDS-defining illness in Europe, with especially high mortality in HIV-negative patients caused by delayed diagnosis and low awareness. This study aim...

The development of scaffolding obtained by electrospinning is widely used in tissue engineering due to porous and fibrous structures that can mimic the extracellular matrix. In this study, poly (lactic-co-glycolic acid) (PLGA)/collagen fibers were fa...

Candida albicans is a common fungal pathogen. Biofilm formation on various surfaces is an important determinant of C. albicans pathogenicity. Our previous results demonstrated the high potential of cannabidiol (CBD) to affect C. albicans biofilms. Ba...

The present study aimed to develop and prepare new polymer/herbicide formulations for their potential application in environment-friendly, controlled release systems of agrochemicals. Selected biodegradable polymers, including L-Lactide/Glycolide/PEG...

Background/Objectives: Primary dysmenorrhea is a prevalent condition that causes severe uterine cramps in women worldwide. The objective of this work was to synthesize and characterize a novel immediate-release system using vitexin and ZIF-8, and to...

Growing evidence has demonstrated the influence of internal nitrogen (N) and phosphorus (P) on harmful algae blooms in eutrophic freshwater ecosystems. However, the main controlling factors for internal N and P release risks, and whether these factor...