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4,167 Results Found

  • Article
  • Open Access
3 Citations
4,794 Views
11 Pages

22 November 2020

A model-based design allows representing complex, multi-domain systems as interconnected functional blocks, yielding graphical, intuitive information about the overall project, besides simplifying simulation. This work proposes using the modular appr...

  • Article
  • Open Access
6 Citations
3,930 Views
21 Pages

Sea cucumber manual monitoring and fishing present various issues, including high expense and high risk. Meanwhile, compared to underwater bionic robots, employing autonomous underwater robots for sea cucumber monitoring and capture also has drawback...

  • Article
  • Open Access
1 Citations
1,011 Views
15 Pages

Design and Performance Study of a Six-Bar Mechanism Underwater Robot Based on Cownose Ray Bionics

  • Yichen Chu,
  • Xiaohan Wang,
  • Tiancheng Hao,
  • Yanhui Fu,
  • Yubing Duan and
  • Tianbiao Yu

This paper focuses on the formidable challenges that underwater robots encounter in complex marine environments. To address these issues, inspired by the cownose ray, an innovative scheme is proposed, utilizing four six-bar mechanisms to mimic its pe...

  • Article
  • Open Access
2,489 Views
24 Pages

Mechanical Structure Design and Experimental Study of Gamma-ray Monitor for Small Satellite Payload

  • Pengfei Guo,
  • Hongbing Xin,
  • Sheng Yang,
  • Shaolin Xiong,
  • Xinqiao Li,
  • Zhenghua An and
  • Dali Zhang

31 October 2022

In this paper, a novel mechanical structure for a gamma-ray monitor (GRM) is designed for a small satellite payload. Its structural stiffness, strength and dynamic response are directly related to the performance of the novel GRM, which must meet the...

  • Article
  • Open Access
19 Citations
5,655 Views
14 Pages

Design of an In-Operando Cell for X-Ray and Neutron Imaging of Oxygen-Depolarized Cathodes in Chlor-Alkali Electrolysis

  • Marcus Gebhard,
  • Melanie Paulisch,
  • André Hilger,
  • David Franzen,
  • Barbara Ellendorff,
  • Thomas Turek,
  • Ingo Manke and
  • Christina Roth

18 April 2019

Oxygen-depolarized cathodes are a novel concept to be used in chlor-alkali electrolysis in order to generate significant energy savings. In these porous gas diffusion electrodes, hydrophilic and catalytically active microsized silver grains and a hyd...

  • Article
  • Open Access
13 Citations
4,539 Views
13 Pages

High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors

  • Thomas Fischer,
  • Symeon M. Koulas,
  • Anastasia S. Tsagkarakou,
  • Efthimios Kyriakis,
  • George A. Stravodimos,
  • Vassiliki T. Skamnaki,
  • Panagiota G.V. Liggri,
  • Spyros E. Zographos,
  • Rainer Riedl and
  • Demetres D. Leonidas

Structure-based design and synthesis of two biphenyl-N-acyl-β-d-glucopyranosylamine derivatives as well as their assessment as inhibitors of human liver glycogen phosphorylase (hlGPa, a pharmaceutical target for type 2 diabetes) is presented. X-...

  • Article
  • Open Access
8 Citations
2,817 Views
17 Pages

14 November 2022

Evaluating the structure of soil prior to building construction is valuable in a large variety of geotechnical and civil engineering applications. To built an effective framework for assessing the strength of the stabilised soil, the presented workfl...

  • Article
  • Open Access
2,371 Views
10 Pages

Design and Performance of a Low-Energy Gamma-Ray Trigger System for HERD

  • Luis Fariña,
  • Keerthana Lathika,
  • Giulio Lucchetta,
  • Monong Yu,
  • Joan Boix,
  • Laia Cardiel-Sas,
  • Oscar Blanch,
  • Manel Martinez and
  • Javier Rico

The High Energy cosmic-Radiation Detection (HERD) facility has been proposed as one of the main experiments on board the Chinese space station. HERD is scheduled to be installed around 2027 and to operate for at least 10 years. Its main scientific go...

  • Article
  • Open Access
3 Citations
2,422 Views
24 Pages

A Collection of Formulae for the Design of Compton Back-Scattering X-ray Sources

  • Giuseppe Dattoli,
  • Emanuele Di Palma and
  • Vittoria Petrillo

18 February 2023

Along with the development of FEL X-ray sources, the design and the construction of Compton Back-Scattering (CBS) devices for different applications are being pursued. These sources are designed to provide monochromatic, high peak brightness tunable...

  • Article
  • Open Access
2,357 Views
18 Pages

Target Design in SEM-Based Nano-CT and Its Influence on X-ray Imaging

  • Jonas Fell,
  • Felix Wetzler,
  • Michael Maisl and
  • Hans-Georg Herrmann

Nano-computed tomography (nano-CT) based on scanning electron microscopy (SEM) is utilized for multimodal material characterization in one instrument. Since SEM-based CT uses geometrical magnification, X-ray targets can be adapted without any further...

  • Article
  • Open Access
8 Citations
3,933 Views
16 Pages

A Smart Multi-Plane Detector Design for Ultrafast Electron Beam X-ray Computed Tomography

  • André Bieberle,
  • Dominic Windisch,
  • Kerolos Iskander,
  • Martina Bieberle and
  • Uwe Hampel

10 September 2020

In this paper, a smart detector design for novel multi-plane ultrafast electron beam X-ray computed tomography is presented. The concept is based on multi-plane electron beam scanning on a transparent X-ray target and elongated cuboid-shape scintilla...

  • Article
  • Open Access
5 Citations
8,336 Views
20 Pages

Design of a Tunable Snapshot Multispectral Imaging System through Ray Tracing Simulation

  • Mengjia Ding,
  • Peter WT Yuen,
  • Jonathan Piper,
  • Peter Godfree,
  • Ayan Chatterjee,
  • Usman Zahidi,
  • Senthurran Selvagumar,
  • David James and
  • Mark Richardson

Research on snapshot multispectral imaging has been popular in the remote sensing community due to the high demands of video-rate remote sensing system for various applications. Existing snapshot multispectral imaging techniques are mainly of a fixed...

  • Article
  • Open Access
13 Citations
4,166 Views
21 Pages

Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy

  • Joël Daouk,
  • Mathilde Iltis,
  • Batoul Dhaini,
  • Denise Béchet,
  • Philippe Arnoux,
  • Paul Rocchi,
  • Alain Delconte,
  • Benoît Habermeyer,
  • François Lux and
  • Céline Frochot
  • + 3 authors

22 April 2021

X-ray-induced photodynamic therapy is based on the energy transfer from a nanoscintillator to a photosensitizer molecule, whose activation leads to singlet oxygen and radical species generation, triggering cancer cells to cell death. Herein, we synth...

  • Article
  • Open Access
1 Citations
1,735 Views
20 Pages

14 May 2024

X-ray tomography is an effective non-destructive testing method for industrial quality control. Limited-angle tomography can be used to reduce the amount of data that need to be acquired and thereby speed up the process. In some industrial applicatio...

  • Article
  • Open Access
891 Views
26 Pages

Compton Camera X-Ray Fluorescence Imaging Design and Image Reconstruction Algorithm Optimization

  • Shunmei Lu,
  • Kexin Peng,
  • Peng Feng,
  • Cheng Lin,
  • Qingqing Geng and
  • Junrui Zhang

3 September 2025

Traditional X-ray fluorescence computed tomography (XFCT) suffers from issues such as low photon collection efficiency, slow data acquisition, severe noise interference, and poor imaging quality due to the limitations of mechanical collimation. This...

  • Article
  • Open Access
5 Citations
3,040 Views
10 Pages

Design and Use of Portable X-ray Fluorescence Devices for the Analysis of Heritage Materials

  • Maurizio Chiti,
  • Daniele Chiti,
  • Federico Chiarelli,
  • Raffaella Donghia,
  • Adolfo Esposito,
  • Marco Ferretti and
  • Astrik Gorghinian

X-ray fluorescence (XRF) is a successful technique often used for the elemental analysis of cultural heritage artefacts. It is non-invasive, the equipment can be miniaturized and made portable and it allows addressing crucial issues such as the fabri...

  • Article
  • Open Access
2 Citations
4,292 Views
26 Pages

15 November 2021

In this study, we analyzed the problem of a compact furnace, to be used for in situ experiments in a cone-beam X-ray microtomography commercial system. The design process was accomplished and outlined through its main steps, until the realization of...

  • Article
  • Open Access
2 Citations
1,977 Views
11 Pages

14 November 2024

Health care workers performing radiography on patients in hospitals typically wear aprons for radiation protection. Protective properties are achieved through a combination of shielding materials and polymers. Various shielding materials are mixed wi...

  • Communication
  • Open Access
4 Citations
3,178 Views
8 Pages

Design of a Hybrid Split-Delay Line for Hard X-ray Free-Electron Lasers

  • Yihui Xu,
  • Chen Wu,
  • Jiadong Fan,
  • Zhen Wang,
  • Yajun Tong,
  • Qiushi Huang,
  • Chuan Yang,
  • Xiaohao Dong,
  • Huaidong Jiang and
  • Zhi Liu

26 February 2022

High repetition-rate X-ray free-electron lasers (XFELs) enable the study of fast dynamics on microsecond time scales. Split-delay lines (SDLs) further bring the time scale down to femtoseconds by splitting and delaying the XFEL pulses. Crystals and m...

  • Article
  • Open Access
5,364 Views
11 Pages

Buried P-Well (BPW) technology was used in silicon-on-insulator pixels (SOIPIX) to suppress the back-gate effect, the major challenge in SOIPIX. In this work, we have designed and optimized two novel pixel structures, which are based on different BPW...

  • Proceeding Paper
  • Open Access
1,013 Views
12 Pages

The Payload Design of the CUbesat Solar Polarimeter (CUSP), for Space Weather and Solar Flares X-Ray Polarimetry

  • Giovanni Lombardi,
  • Sergio Fabiani,
  • Ettore Del Monte,
  • Emanuele Di Meo,
  • Andrea Lopez,
  • Marco Camponeschi,
  • Marco E. Biancolini,
  • Daniele Brienza,
  • Immacolata Donnarumma and
  • Silvia Natalucci
  • + 2 authors

The CUbesat Solar Polarimeter (CUSP) project is a CubeSat mission orbiting the Earth aimed to measure the linear polarization of solar flares in the hard X-ray band by means of a Compton scattering polarimeter. CUSP is a project in the framework of t...

  • Article
  • Open Access
30 Citations
5,508 Views
15 Pages

Bionic propulsion has advantages over traditional blade propellers, such as efficiency and noise control. Existing research on ray-inspired robot fish has mainly focused on a single type of pectoral fin as bionic propeller, which only performed well...

  • Article
  • Open Access
188 Views
23 Pages

Simulation and Design of a CubeSat-Compatible X-Ray Photovoltaic Payload Using Timepix3 Sensors

  • Ashraf Farahat,
  • Juan Carlos Martinez Oliveros and
  • Stuart D. Bale

30 November 2025

This study investigates the use of Si and CdTe-based Timepix3 detectors for photovoltaic energy conversion using solar X-rays and other high-energy electromagnetic radiation in space. As space missions increasingly rely on miniaturized platforms like...

  • Article
  • Open Access
16 Citations
4,080 Views
16 Pages

25 July 2022

Bionic propulsion has certain advantages over traditional propellers. Much research on pectoral fins as bionic propellers for ray-inspired robots has been made, but rarely did they compare the hydrodynamic performance of different fins on the same pl...

  • Article
  • Open Access
9 Citations
4,351 Views
14 Pages

10 March 2020

The frequent terrorist attacks in subways has dramatically increased the necessity and importance of security check systems (SCSs). The implementation of a SCS in China has successfully eliminated lots of potential safety hazards. However, the excess...

  • Article
  • Open Access
23 Citations
4,173 Views
15 Pages

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases

  • Majid Ali,
  • Murat Bozdag,
  • Umar Farooq,
  • Andrea Angeli,
  • Fabrizio Carta,
  • Paola Berto,
  • Giuseppe Zanotti and
  • Claudiu T. Supuran

A drug design strategy of carbonic anhydrase inhibitors (CAIs) belonging to sulfonamides incorporating ureidoethylaminobenzyl tails is presented. A variety of substitution patterns on the ring and the tails, located on para- or meta- positions with r...

  • Article
  • Open Access
2 Citations
1,519 Views
17 Pages

Design and Test of a Calibration System for Avalanche Photodiodes Used in X-Ray Compton Polarimeters for Space

  • Andrea Alimenti,
  • Fabrizio Cologgi,
  • Sergio Fabiani,
  • Kostiantyn Torokhtii,
  • Enrico Silva,
  • Ettore Del Monte,
  • Ilaria Baffo,
  • Sergio Bonomo,
  • Daniele Brienza and
  • Riccardo Campana
  • + 33 authors

15 December 2024

The development and calibration of a measurement system designed for assessing the performance of the avalanche photodiodes (APDs) used in the Compton scattering polarimeter of the CUSP project is discussed in this work. The designed system is able t...

  • Article
  • Open Access
654 Views
11 Pages

Optimization of Tungsten Anode Target Design for High-Energy Microfocus X-Ray Sources via Geant4 Monte Carlo Simulation

  • Yuetian Liu,
  • Lili Li,
  • Yiheng Liu,
  • Xue Zhang,
  • Liwei Xin,
  • Zhengkun Fu,
  • Jinshou Tian,
  • Wei Zhao and
  • Duan Luo

27 October 2025

High-energy microfocus X-ray sources are increasingly applied in non-destructive testing, high-resolution imaging, and additive manufacturing. The design and optimization of the anode target critically determine source efficiency, spectral characteri...

  • Article
  • Open Access
2 Citations
2,708 Views
23 Pages

X-ray Free Electron Laser Accelerator Lattice Design Using Laser-Assisted Bunch Compression

  • Haoran Xu,
  • Petr M. Anisimov,
  • Bruce E. Carlsten,
  • Leanne D. Duffy,
  • Quinn R. Marksteiner and
  • River R. Robles

10 February 2023

We report the start-to-end modeling of our accelerator lattice design employing a laser-assisted bunch compression (LABC) scheme in an X-ray free electron laser (XFEL), using the proposed Matter-Radiation Interactions in Extremes (MaRIE) XFEL paramet...

  • Article
  • Open Access
1 Citations
2,648 Views
27 Pages

Design of Monolithic Bi-Layer High-Z PAL-Si Hard X-ray CMOS Image Sensors for Quantum Efficiency Enhancement

  • Eldred Lee,
  • Kevin D. Larkin,
  • Xin Yue,
  • Zhehui Wang,
  • Eric R. Fossum and
  • Jifeng Liu

This article experimentally investigates the inception of an innovative hard X-ray photon energy attenuation layer (PAL) to advance high-energy X-ray detection (20–50 keV). A bi-layer design with a thin film high-Z PAL on the top and Si image s...

  • Article
  • Open Access
2 Citations
2,566 Views
20 Pages

10 November 2022

Composite aerogels can include fibers, opacifiers and binders but are rarely designed and optimized to achieve the best thermal/mechanical efficiency. This paper proposes a three-dimensional X-ray tomography-based method for designing composites. Two...

  • Article
  • Open Access
12 Citations
3,639 Views
10 Pages

19 February 2020

Developments in 3D printing and CT scanning technologies have facilitated the imitation of natural wood structures. However, creating composites from the elementary features of anisotropic wood structures remains a new frontier. This paper aims to in...

  • Article
  • Open Access
9 Citations
6,438 Views
24 Pages

Low-Power, Subthreshold Reference Circuits for the Space Environment: Evaluated with γ-rays, X-rays, Protons and Heavy Ions

  • Charalambos M. Andreou,
  • Diego Miguel González-Castaño,
  • Simone Gerardin,
  • Marta Bagatin,
  • Faustino Gómez Rodriguez,
  • Alessandro Paccagnella,
  • Alexander V. Prokofiev,
  • Arto Javanainen,
  • Ari Virtanen and
  • Valentino Liberali
  • + 3 authors

The radiation tolerance of subthreshold reference circuits for space microelectronics is presented. The assessment is supported by measured results of total ionization dose and single event transient radiation-induced effects under γ -rays...

  • Article
  • Open Access
660 Views
18 Pages

Designing a transmission line (TL) for a widely tunable, broadband terahertz radiation source presents substantial challenges due to the complexity of beam dynamics and spectral characteristics. Here, we investigate the propagation of the most signif...

  • Article
  • Open Access
21 Citations
6,736 Views
19 Pages

Light Weight, Easy Formable and Non-Toxic Polymer-Based Composites for Hard X-ray Shielding: A Theoretical and Experimental Study

  • Mattia Lopresti,
  • Gabriele Alberto,
  • Simone Cantamessa,
  • Giorgio Cantino,
  • Eleonora Conterosito,
  • Luca Palin and
  • Marco Milanesio

Composite lightweight materials for X-ray shielding applications were studied and developed with the goal of replacing traditional screens made of lead and steel, with innovative materials with similar shielding properties, but lighter, more easily f...

  • Article
  • Open Access
24 Citations
3,511 Views
12 Pages

Study on a High-Boron-Content Stainless Steel Composite for Nuclear Radiation

  • Wei-Qiang Sun,
  • Guang Hu,
  • Xiao-Hang Yu,
  • Jian Shi,
  • Hu Xu,
  • Rong-Jun Wu,
  • Chao He,
  • Qiang Yi and
  • Hua-Si Hu

19 November 2021

In this research, a high-boron-content composite material with both neutron and γ rays shielding properties was developed by an optimized design and manufacture. It consists of 304 stainless steel as the matrix and spherical boron carbide (B4C) parti...

  • Article
  • Open Access
2 Citations
2,736 Views
16 Pages

4 January 2021

Laser-based methods are widely used techniques for thermonuclear plasma diagnostics, since they can probe the internal of the plasma, being contactless and non-invasive. The interferometer, the polarimeter and Thomson scattering are the most widespre...

  • Article
  • Open Access
1,855 Views
20 Pages

21 January 2025

The Malaysian Department of Occupational Safety and Health (DOSH) reported that noise-induced hearing loss (NIHL) accounted for 92% of occupational diseases in 2019. To address this, accurate risk assessment is crucial. The current noise evaluation m...

  • Review
  • Open Access
53 Citations
12,136 Views
23 Pages

8 October 2012

Fragment-based drug discovery (FBDD) concerns the screening of low-molecular weight compounds against macromolecular targets of clinical relevance. These compounds act as starting points for the development of drugs. FBDD has evolved and grown in pop...

  • Article
  • Open Access
24 Citations
2,803 Views
12 Pages

10 May 2021

This paper aims to characterize the three-dimensional (3D) internal structure evolution of asphalt mixtures under freeze–thaw cycles. Asphalt mixtures with three levels of design void content (3%, 5%, and 7%) were prepared in the laboratory. Subseque...

  • Article
  • Open Access
535 Views
26 Pages

11 September 2025

In many practical scientific studies, two-way analysis of variance (ANOVA) and linear response surface methods are used for determining whether two or more similar compounds (substances, agents, or drugs) interact synergistically, antagonistically or...

  • Article
  • Open Access
7 Citations
1,664 Views
21 Pages

25 September 2024

To tackle the shortcomings of the Dung Beetle Optimization (DBO) Algorithm, which include slow convergence speed, an imbalance between exploration and exploitation, and susceptibility to local optima, a Somersault Foraging and Elite Opposition-Based...

  • Article
  • Open Access
979 Views
20 Pages

3 April 2025

This paper presents an interactive online e-portal development and application using Shiny/R version 4.4.0 programming for personalised varifocal lens surface design and manufacturing in an agile and responsive manner. Varifocal lenses are specialise...

  • Review
  • Open Access
10 Citations
10,441 Views
24 Pages

Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines

  • Monica L. Fernández-Quintero,
  • Nancy D. Pomarici,
  • Anna-Lena M. Fischer,
  • Valentin J. Hoerschinger,
  • Katharina B. Kroell,
  • Jakob R. Riccabona,
  • Anna S. Kamenik,
  • Johannes R. Loeffler,
  • James A. Ferguson and
  • Hailee R. Perrett
  • + 3 authors

18 October 2023

Antibodies and other new antibody-like formats have emerged as one of the most rapidly growing classes of biotherapeutic proteins. Understanding the structural features that drive antibody function and, consequently, their molecular recognition is cr...

  • Article
  • Open Access
3 Citations
3,147 Views
20 Pages

Data Analysis and Filter Optimization for Pulse-Amplitude Measurement: A Case Study on High-Resolution X-ray Spectroscopy

  • Kasun Sameera Mannatunga,
  • Bruno Valinoti,
  • Werner Florian Samayoa,
  • Maria Liz Crespo,
  • Andres Cicuttin,
  • Jerome Folla Kamdem,
  • Luis Guillermo Garcia and
  • Sergio Carrato

24 June 2022

In this study, we present a procedure to optimize a set of finite impulse response filter (FIR) coefficients for digital pulse-amplitude measurement. Such an optimized filter is designed using an adapted digital penalized least mean square (DPLMS) me...

  • Article
  • Open Access
5 Citations
3,610 Views
13 Pages

Modular Line-Focused Space Solar Power Satellite

  • Yang Yang,
  • Guanheng Fan,
  • Xiangfei Ji and
  • Mengchen Pei

The Space Solar Power Satellite is an ultra-large space structure, which collects sunlight directly in space and then transmits it into the ground. Since the idea was invented in 1968, scientists around the world have proposed several typical concept...

  • Article
  • Open Access
16 Citations
4,758 Views
25 Pages

On the Use of Perforated Sound Absorption Systems for Variable Acoustics Room Design

  • Andreia Pereira,
  • Anna Gaspar,
  • Luís Godinho,
  • Paulo Amado Mendes,
  • Diogo Mateus,
  • Jesus Carbajo,
  • Jaime Ramis and
  • Pedro Poveda

15 November 2021

An important challenge for acoustic engineers in room acoustics design is related to the acoustic performance of multi-purpose auditoriums, which are typically designed to suit several performance requirements. With this intent, the analysis of sever...

  • Article
  • Open Access
1 Citations
1,929 Views
46 Pages

A 1.8 m Class Pathfinder Raman LIDAR for the Northern Site of the Cherenkov Telescope Array Observatory—Technical Design

  • Otger Ballester,
  • Oscar Blanch,
  • Joan Boix,
  • Paolo G. Calisse,
  • Anna Campoy-Ordaz,
  • Sidika Merve Çolak,
  • Vania Da Deppo,
  • Michele Doro,
  • Lluís Font and
  • Eudald Font-Pladevall
  • + 15 authors

18 March 2025

This paper presents the technical design of the pathfinder Barcelona Raman LIDAR (pBRL) for the northern site of the Cherenkov Telescope Array Observatory (CTAO-N) located at the Roque de los Muchachos Observatory (ORM). The pBRL is developed for con...

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