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70 Results Found

  • Proceeding Paper
  • Open Access
1 Citations
1,507 Views
8 Pages

Conventional maximum likelihood-based algorithms for 3D Compton image reconstruction are often stuck with slow convergence and large data volume, which could be unsuitable for some practical applications, such as nuclear engineering. Taking advantage...

  • Article
  • Open Access
3 Citations
3,808 Views
25 Pages

30 January 2023

An informative measurement is the most efficient way to gain information about an unknown state. We present a first-principles derivation of a general-purpose dynamic programming algorithm that returns an optimal sequence of informative measurements...

  • Article
  • Open Access
1 Citations
1,273 Views
15 Pages

5 February 2025

The optimal allocation of buffers is an important research issue in the area of manufacturing system design and optimization, as buffers can have a large impact on system performance. In this study, we consider one of the most common buffer allocatio...

  • Article
  • Open Access
6 Citations
2,188 Views
28 Pages

7 March 2023

Line planning problems and differential pricing problems are complementary processes in the railway system, but these two problems were generally considered separate processes in most of the existing literature. This paper studies a time-dependent li...

  • Feature Paper
  • Article
  • Open Access
661 Views
30 Pages

20 October 2025

An assembly line is a manufacturing process commonly used in the production of commodity goods. The assembly process is divided into elementary tasks that are sequentially performed at serially arranged workstations. Among the various challenges that...

  • Article
  • Open Access
9 Citations
2,389 Views
19 Pages

Application of Surrogate Optimization Routine with Clustering Technique for Optimal Design of an Induction Motor

  • Aswin Balasubramanian,
  • Floran Martin,
  • Md Masum Billah,
  • Osaruyi Osemwinyen and
  • Anouar Belahcen

17 August 2021

This paper proposes a new surrogate optimization routine for optimal design of a direct on line (DOL) squirrel cage induction motor. The geometry of the motor is optimized to maximize its electromagnetic efficiency while respecting the constraints, s...

  • Article
  • Open Access
1,551 Views
23 Pages

12 June 2025

Due to the unbalanced temporal and spatial distribution of the passenger flow on metro lines during peak hours, the implementation of passenger flow control strategies effectively ensures operational safety and travel efficiency for passengers. In th...

  • Article
  • Open Access
3 Citations
3,106 Views
30 Pages

11 May 2022

The capacity of some busy rail lines is increasingly tight and passenger demand far exceeds the railway capacity. To schedule as many trains as possible in order to satisfy more transportation demands, we studied the capacity-oriented train schedulin...

  • Article
  • Open Access
10 Citations
2,353 Views
19 Pages

12 July 2022

Implementing intelligent reflecting surfaces (IRSs), in high frequency based beyond 5G networks, has become a necessity to overcome the harsh blockage issues that exist in these bands. IRSs can supply user equipment (UEs) with multi alternative virtu...

  • Article
  • Open Access
44 Citations
7,537 Views
32 Pages

1 September 2017

Increasing demand for electricity has placed heavy stress on power system security. Therefore, this paper focuses on the problem of how to maximize power system static security in terms of branch loading and voltage level under normal operation and e...

  • Article
  • Open Access
1 Citations
1,879 Views
30 Pages

15 December 2022

The problem of wildfire spread prediction presents a high degree of complexity due in large part to the limitations for providing accurate input parameters in real time (e.g., wind speed, temperature, moisture of the soil, etc.). This uncertainty in...

  • Review
  • Open Access
170 Citations
13,616 Views
20 Pages

The SIC Question: History and State of Play

  • Christopher A. Fuchs,
  • Michael C. Hoang and
  • Blake C. Stacey

18 July 2017

Recent years have seen significant advances in the study of symmetric informationally complete (SIC) quantum measurements, also known as maximal sets of complex equiangular lines. Previously, the published record contained solutions up to dimension 6...

  • Article
  • Open Access
1 Citations
3,559 Views
15 Pages

10 January 2023

This paper presents an approach for the solution of a zero-sum differential game associated with a nonlinear state-feedback H∞ control problem. Instead of using the approximation methods for solving the corresponding Hamilton–Jacobi&ndash...

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,555 Views
21 Pages

The deployment of millimeter waves can fulfil the stringent requirements of high bandwidth and high energy efficiency in fifth generation (5G) networks. Still, millimeter waves communication is challenging because it requires line of sight (LOS). The...

  • Article
  • Open Access
2 Citations
1,442 Views
24 Pages

9 September 2025

Maritime transport is vital to the global economy, yet the frequency of natural disasters at sea continues to rise, resulting in more persons falling overboard. Therefore, effective maritime search and rescue (SAR) hinges on accurately predicting the...

  • Article
  • Open Access
8 Citations
7,002 Views
17 Pages

14 January 2017

Every finite simple group P can be generated by two of its elements. Pairs of generators for P are available in the Atlas of finite group representations as (not necessarily minimal) permutation representations P . It is unusual, but significant...

  • Article
  • Open Access
2 Citations
4,641 Views
24 Pages

26 July 2020

In western China, railway lines are sparse, and there is a large fluctuation in transport demand under different transportation scenarios, which yields severe difficulties in setting up a signaling system and making a train timetable. To meet the flu...

  • Article
  • Open Access
27 Citations
4,965 Views
12 Pages

10 April 2019

Hepatocellular carcinoma (HCC) is one of the most deadly genetic diseases, but surprisingly chemotherapeutic approaches against HCC are only limited to a few targets. In particular, considering the difficulty of a chemotherapeutic drug development in...

  • Article
  • Open Access
14 Citations
6,600 Views
21 Pages

Disparities in Cisplatin-Induced Cytotoxicity—A Meta-Analysis of Selected Cancer Cell Lines

  • Małgorzata Ćwiklińska-Jurkowska,
  • Małgorzata Wiese-Szadkowska,
  • Sabina Janciauskiene and
  • Renata Paprocka

30 July 2023

Cisplatin is a classic anticancer drug widely used as a reference drug to test new metal complex drug candidates. We found an unexpected diversity in cisplatin-related cytotoxicity values, expressed as IC50 (the half-maximal inhibitory concentration)...

  • Article
  • Open Access
2 Citations
1,333 Views
19 Pages

Mathematical Models for Coverage with Star Tree Backbone Topology for 5G Millimeter Waves Networks

  • Sergio Cordero,
  • Pablo Adasme,
  • Ali Dehghan Firoozabadi,
  • Renata Lopes Rosa and
  • Demóstenes Zegarra Rodríguez

18 January 2025

This paper proposes mathematical optimization models for solving the network planning problem using millimeter wave technology for 5G wireless communications networks. To this end, it is assumed that a set of users, M={1,…,m}, and a set of bas...

  • Article
  • Open Access
27 Citations
5,249 Views
21 Pages

A New Approach for Real Time Train Energy Efficiency Optimization

  • Agostinho Rocha,
  • Armando Araújo,
  • Adriano Carvalho and
  • João Sepulveda

5 October 2018

Efficient use of energy is currently a very important issue. As conventional energy resources are limited, improving energy efficiency is, nowadays, present in any government policy. Railway systems consume a huge amount of energy, during normal oper...

  • Article
  • Open Access
3 Citations
1,753 Views
15 Pages

In current practices of determining continental shelf area, the measured sediment thickness data do not effectively reflect the distribution of sediments across the area due to its dispersed nature. This issue raises potential limitations in unknown...

  • Article
  • Open Access
3 Citations
2,506 Views
17 Pages

Micro-Grooved Pipe Design of Parabolic Trough by Metaheuristic Optimization: An Empirical Comparison

  • Valentín Osuna-Enciso,
  • Marco Pérez-Cisneros and
  • Daniel Zaldívar-Navarro

17 January 2020

Pipe design is one of the most significant research lines in the area of parabolic semi-cylindrical solar collectors. The main idea behind pipe design is to increase the capillarity angle by expanding the total area being heated, therefore boosting t...

  • Review
  • Open Access
19 Citations
3,847 Views
14 Pages

New and Old Horizons for an Ancient Drug: Pharmacokinetics, Pharmacodynamics, and Clinical Perspectives of Dimethyl Fumarate

  • Paolinelli Matteo,
  • Diotallevi Federico,
  • Martina Emanuela,
  • Radi Giulia,
  • Bianchelli Tommaso,
  • Giacchetti Alfredo,
  • Campanati Anna and
  • Offidani Annamaria

(1) Background: In their 60-year history, dimethyl fumarate and other salts of fumaric acid have been used for the treatment of psoriasis and other immune-mediated diseases for their immune-modulating properties. Over the years, new mechanisms of act...

  • Article
  • Open Access
831 Views
17 Pages

28 February 2025

Real-time pricing is an ideal pricing mechanism for regulating the balance of power supply and demand in smart grid. Considering the differences in electricity consumption risks among different types of users, a social welfare maximization model with...

  • Review
  • Open Access
1 Citations
3,556 Views
29 Pages

Multi-Pathway Study for Oxaliplatin Resistance Reduction

  • Tong Ye,
  • Chen Wu,
  • Jintong Na,
  • Xiyu Liu and
  • Yong Huang

Chemotherapy for cancer frequently uses platinum-based medications, including oxaliplatin, carboplatin, and cisplatin; however, due to their high systemic toxicity, lack of selectivity, drug resistance, and other side effects, platinum-based medicati...

  • Article
  • Open Access
1 Citations
4,922 Views
12 Pages

Optimal Color Lighting for Scanning Images of Flat Panel Display using Simplex Search

  • HyungTae Kim,
  • EungJoo Ha,
  • KyungChan Jin and
  • ByungWook Kim

12 November 2018

A system for inspecting flat panel displays (FPDs) acquires scanning images using multiline charge-coupled device (CCD) cameras and industrial machine vision. Optical filters are currently installed in front of these inspection systems to obtain high...

  • Article
  • Open Access
4 Citations
1,783 Views
20 Pages

20 January 2024

In recent years, the global resource shortage has become a serious issue. Recycling end-of-life (EOL) products is conducive to resource reuse and circular economy and can mitigate the resource shortage issue. The disassembly of EOL products is the fi...

  • Article
  • Open Access
29 Citations
7,590 Views
11 Pages

Cytotoxicity of Triterpenes from Green Walnut Husks of Juglans mandshurica Maxim in HepG-2 Cancer Cells

  • Yuanyuan Zhou,
  • Bingyou Yang,
  • Zhaoxi Liu,
  • Yanqiu Jiang,
  • Yuxin Liu,
  • Lei Fu,
  • Xiaoli Wang and
  • Haixue Kuang

22 October 2015

Among the classes of identified natural products, triterpenoids, one of the largest families, have been studied extensively for their diverse structures and variety of biological activities, including antitumor effects. In the present study, a phytoc...

  • Article
  • Open Access
14 Citations
3,384 Views
15 Pages

Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes

  • Anne Vessières,
  • Emie Quissac,
  • Nolwenn Lemaire,
  • Agusti Alentorn,
  • Patrycja Domeracka,
  • Pascal Pigeon,
  • Marc Sanson,
  • Ahmed Idbaih and
  • Maïté Verreault

27 September 2021

Glioblastoma (GBM) is the most frequent and deadliest primary brain cancer in adults, justifying the search for new treatments. Some members of the iron-based ferrocifen family have demonstrated a high cytotoxic effect on various cancer cell lines vi...

  • Article
  • Open Access
17 Citations
10,865 Views
27 Pages

23 September 2015

Sea-based infrared search and track (IRST) is important for homeland security by detecting missiles and asymmetric boats. This paper proposes a novel scheme to interpret various infrared scenes by classifying the infrared background types and detecti...

  • Systematic Review
  • Open Access
28 Citations
19,956 Views
21 Pages

Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review—Part II

  • Bruno Viaggi,
  • Alice Cangialosi,
  • Martin Langer,
  • Carlo Olivieri,
  • Andrea Gori,
  • Alberto Corona,
  • Stefano Finazzi and
  • Antonello Di Paolo

3 September 2022

In patients that are admitted to intensive care units (ICUs), the clinical outcome of severe infections depends on several factors, as well as the early administration of chemotherapies and comorbidities. Antimicrobials may be used in off-label regim...

  • Article
  • Open Access
16 Citations
3,395 Views
23 Pages

11 May 2020

This paper proposes the concept “active energy agent (AEA)” to characterize the autonomous and interactive entities of power system. The future distribution network is a peer-to-peer (P2P) community based on numbers of AEAs. A two-stage &...

  • Article
  • Open Access
4 Citations
2,870 Views
17 Pages

How Deep Learning in Antiviral Molecular Profiling Identified Anti-SARS-CoV-2 Inhibitors

  • Mohammed Ali,
  • In Ho Park,
  • Junebeom Kim,
  • Gwanghee Kim,
  • Jooyeon Oh,
  • Jin Sun You,
  • Jieun Kim,
  • Jeon-Soo Shin and
  • Sang Sun Yoon

24 November 2023

The integration of artificial intelligence (AI) into drug discovery has markedly advanced the search for effective therapeutics. In our study, we employed a comprehensive computational–experimental approach to identify potential anti-SARS-CoV-2...

  • Article
  • Open Access
1,062 Views
15 Pages

28 November 2024

Addressing the issue of linear frequency modulation (LFM) interference in GNSS positioning, this paper proposes an interference suppression method based on energy residual searching, incorporating the fractional Fourier transform (FrFT) for improved...

  • Article
  • Open Access
6 Citations
3,734 Views
21 Pages

Adaptive Large Neighborhood Search for a Production Planning Problem Arising in Pig Farming

  • Nat Praseeratasang,
  • Rapeepan Pitakaso,
  • Kanchana Sethanan,
  • Sasitorn Kaewman and
  • Paulina Golinska-Dawson

This article aims to resolve a particular production planning and workforce assignment problem. Many production lines may have different production capacities while producing the same product. Each production line is composed of three production stag...

  • Systematic Review
  • Open Access
2 Citations
4,760 Views
15 Pages

Time-Course of Recovery for Biomarkers and Physical Performance after Strenuous Military Training: A Systematic Review

  • Julius Granlund,
  • Heikki Kyröläinen,
  • Matti Santtila,
  • Bradley C. Nindl,
  • Kai Pihlainen and
  • Tommi Ojanen

13 December 2023

The objective of the present review was to evaluate the time-course of recovery of biochemical marker levels and physical performance after strenuous military training, and identify which biomarkers are affected. A systematic literature search was co...

  • Article
  • Open Access
22 Citations
8,772 Views
6 Pages

WeReview: CRISPR Tools—Live Repository of Computational Tools for Assisting CRISPR/Cas Experiments

  • Rafael Torres-Perez,
  • Juan A. Garcia-Martin,
  • Lluis Montoliu,
  • Juan C. Oliveros and
  • Florencio Pazos

Computational tools are essential in the process of designing a CRISPR/Cas experiment for the targeted modification of an organism’s genome. Among other functionalities, these tools facilitate the design of a guide-RNA (gRNA) for a given nuclea...

  • Article
  • Open Access
23 Citations
5,018 Views
23 Pages

2 November 2017

Due to growing worldwide energy demand, the search for diversification of the energy matrix stands out as an important research topic. Bioethanol represents a notable alternative of renewable and environmental-friendly energy sources extracted from b...

  • Article
  • Open Access
5 Citations
3,155 Views
22 Pages

Inhibition of HSP90 in Driver Oncogene-Defined Lung Adenocarcinoma Cell Lines: Key Proteins Underpinning Therapeutic Efficacy

  • Ángela Marrugal,
  • Irene Ferrer,
  • Álvaro Quintanal-Villalonga,
  • Laura Ojeda,
  • María Dolores Pastor,
  • Ricardo García-Luján,
  • Amancio Carnero,
  • Luis Paz-Ares and
  • Sonia Molina-Pinelo

7 September 2023

The use of 90 kDa heat shock protein (HSP90) inhibition as a therapy in lung adenocarcinoma remains limited due to moderate drug efficacy, the emergence of drug resistance, and early tumor recurrence. The main objective of this research is to maximiz...

  • Feature Paper
  • Article
  • Open Access
15 Citations
3,213 Views
22 Pages

A Comparison of Fuzzy-Based Energy Management Systems Adjusted by Nature-Inspired Algorithms

  • Diego Arcos-Aviles,
  • Diego Pacheco,
  • Daniela Pereira,
  • Gabriel Garcia-Gutierrez,
  • Enrique V. Carrera,
  • Alexander Ibarra,
  • Paúl Ayala,
  • Wilmar Martínez and
  • Francesc Guinjoan

12 February 2021

The growing energy demand around the world has increased the usage of renewable energy sources (RES) such as photovoltaic and wind energies. The combination of traditional power systems and RESs has generated diverse problems due especially to the st...

  • Article
  • Open Access
6 Citations
3,860 Views
17 Pages

Analysis of the Spatial Patterns of Rainfall across the Agro-Climatic Zones of Jema Watershed in the Northwestern Highlands of Ethiopia

  • Mintesinot Taye,
  • Belay Simane,
  • Benjamin F. Zaitchik,
  • Shimelis Setegn and
  • Yihenew G. Selassie

The association between elevation (agro-climatic zones, ACZs) and the mean annual total rainfall (MATRF) is not straightforward in different parts of the world. This study sought to estimate the amount of MATRF across four elevation zones of Jema wat...

  • Article
  • Open Access
2 Citations
1,338 Views
14 Pages

19 April 2024

The need, or even the obligation, to take care of the natural environment compels a search for new technological solutions, or for known solutions to be adapted to new applications. The maxim is ‘don’t harm, but improve the world for futu...

  • Article
  • Open Access
6 Citations
4,199 Views
23 Pages

5 January 2024

This study is basically and centrally focused on the review of the extant literature in exploring the challenge of the under-utilization of natural fertile land for the cultivation and farming of different crops such as cocoa, palm tree, and cassava,...

  • Article
  • Open Access
2 Citations
3,157 Views
17 Pages

6 October 2021

In optical communications, differential phase shift keying (DPSK) provides a desired modulation format that offers high tolerance to nonlinear effects in high-speed transmissions. A DPSK demodulator converts the phase-coded signal into an intensity-c...

  • Article
  • Open Access
11 Citations
4,162 Views
23 Pages

16 October 2021

UAV equipped three-dimensional (3D) wireless networks can provide a solution for the requirements of 5G communications, such as enhanced Mobile Broadband (eMBB) and massive Machine Type Communications (mMTC). Especially, the introduction of an unmann...

  • Article
  • Open Access
57 Citations
4,283 Views
23 Pages

15 March 2019

The high penetration of distributed generation (DG) units with their power-electronic interfaces may lead to various power quality problems, such as excessive harmonic distortions and increased non-sinusoidal power losses. In this paper, the probabil...

  • Article
  • Open Access
8 Citations
2,619 Views
21 Pages

11 April 2021

We consider the problem of the efficient transmit antenna subset (TAS) selection for maximizing the signal-to-interference-plus-noise ratio (SINR) of multiuser space–time line code (MU–STLC) systems. The exhaustive search for optimal TAS selection is...

  • Article
  • Open Access
553 Citations
24,383 Views
11 Pages

FLEXBAR—Flexible Barcode and Adapter Processing for Next-Generation Sequencing Platforms

  • Matthias Dodt,
  • Johannes T. Roehr,
  • Rina Ahmed and
  • Christoph Dieterich

14 December 2012

Quantitative and systems biology approaches benefit from the unprecedented depth of next-generation sequencing. A typical experiment yields millions of short reads, which oftentimes carry particular sequence tags. These tags may be: (a) specific to t...

  • Concept Paper
  • Open Access
3 Citations
2,854 Views
17 Pages

A Practical Framework for Academics to Implement Public Engagement Interventions and Measure Their Impact

  • Isolde Martina Busch,
  • Silvia Savazzi,
  • Giuseppe Bertini,
  • Paola Cesari,
  • Olivia Guaraldo,
  • Michela Nosè,
  • Corrado Barbui and
  • Michela Rimondini

Academic institutions have shown an increased interest in the so-called third mission to offer an impactful contribution to society. Indeed, public engagement programs ensure knowledge transfer and help to inspire positive public discourse. We aimed...

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