You are currently on the new version of our website. Access the old version .

16,114 Results Found

  • Article
  • Open Access
3 Citations
1,582 Views
20 Pages

17 February 2025

Seeking inter-organisation cooperation is an important way to achieve communication technology innovation, and dynamic networked cooperation deserves more attention. The present paper aims to reveal the influence of cooperation network evolution on c...

  • Article
  • Open Access
2 Citations
3,728 Views
17 Pages

Evolution Model of Spatial Interaction Network in Online Social Networking Services

  • Jian Dong,
  • Bin Chen,
  • Pengfei Zhang,
  • Chuan Ai,
  • Fang Zhang,
  • Danhuai Guo and
  • Xiaogang Qiu

24 April 2019

The development of online social networking services provides a rich source of data of social networks including geospatial information. More and more research has shown that geographical space is an important factor in the interactions of users in s...

  • Article
  • Open Access
2 Citations
5,190 Views
20 Pages

Drug–Target Interaction Prediction Based on an Interactive Inference Network

  • Yuqi Chen,
  • Xiaomin Liang,
  • Wei Du,
  • Yanchun Liang,
  • Garry Wong and
  • Liang Chen

Drug–target interactions underlie the actions of chemical substances in medicine. Moreover, drug repurposing can expand use profiles while reducing costs and development time by exploiting potential multi-functional pharmacological properties b...

  • Article
  • Open Access
3 Citations
2,868 Views
18 Pages

15 December 2022

Click-through rate (CTR) prediction is crucial for computing advertisement and recommender systems. The key challenge of CTR prediction is to accurately capture user interests and deliver suitable advertisements to the right people. However, there ar...

  • Article
  • Open Access
30 Citations
4,472 Views
19 Pages

31 January 2020

Essential genes are a group of genes that are indispensable for cell survival and cell fertility. Studying human essential genes helps scientists reveal the underlying biological mechanisms of a human cell but also guides disease treatment. Recently,...

  • Review
  • Open Access
70 Citations
12,146 Views
18 Pages

Reconstruction and Application of Protein–Protein Interaction Network

  • Tong Hao,
  • Wei Peng,
  • Qian Wang,
  • Bin Wang and
  • Jinsheng Sun

The protein-protein interaction network (PIN) is a useful tool for systematic investigation of the complex biological activities in the cell. With the increasing interests on the proteome-wide interaction networks, PINs have been reconstructed for ma...

  • Article
  • Open Access
33 Citations
8,003 Views
19 Pages

Graph Neural Network for Protein–Protein Interaction Prediction: A Comparative Study

  • Hang Zhou,
  • Weikun Wang,
  • Jiayun Jin,
  • Zengwei Zheng and
  • Binbin Zhou

19 September 2022

Proteins are the fundamental biological macromolecules which underline practically all biological activities. Protein–protein interactions (PPIs), as they are known, are how proteins interact with other proteins in their environment to perform...

  • Article
  • Open Access
1 Citations
4,142 Views
15 Pages

10 December 2022

Click-through rate prediction is a critical task for computational advertising and recommendation systems, where the key challenge is to model feature interactions between different feature domains. At present, the main click-through rate prediction...

  • Article
  • Open Access
1 Citations
890 Views
25 Pages

Symmetry Alignment–Feature Interaction Network for Human Ear Similarity Detection and Authentication

  • Li Yuan,
  • He-Bin Zhou,
  • Jiang-Yun Li,
  • Li Liu,
  • Xiao-Chai Gu and
  • Ya-Nan Zhao

26 April 2025

In the context of ear-based biometric identity authentication, symmetry between the left and right ears emerges as a pivotal factor, particularly when registration involves one ear and authentication utilizes its contralateral counterpart. The extent...

  • Article
  • Open Access
11 Citations
9,429 Views
18 Pages

Social Network Extraction and Analysis Based on Multimodal Dyadic Interaction

  • Sergio Escalera,
  • Xavier Baró,
  • Jordi Vitrià,
  • Petia Radeva and
  • Bogdan Raducanu

7 February 2012

Social interactions are a very important component in people’s lives. Social network analysis has become a common technique used to model and quantify the properties of social interactions. In this paper, we propose an integrated framework to explore...

  • Article
  • Open Access
1,868 Views
20 Pages

Two-Branch Feature Interaction Fusion Method Based on Generative Adversarial Network

  • Rong Chang,
  • Junpeng Dang,
  • Nanchuan Zhang,
  • Shan Zhao,
  • Shijin Hu,
  • Lin Xing,
  • Haicheng Bai,
  • Chengjiang Zhou and
  • Yang Yang

15 August 2023

This study proposes a fusion method of infrared and visible images based on feature interaction. Existing fusion methods can be classified into two categories based on a single-branch network and a two-branch network. Generative adversarial networks...

  • Article
  • Open Access
15 Citations
5,834 Views
10 Pages

10 November 2016

Non-obstructive azoospermia is a severe infertility factor. Currently, the etiology of this condition remains elusive with several possible molecular pathway disruptions identified in the post-meiotic spermatozoa. In the presented study, in order to...

  • Article
  • Open Access
5 Citations
2,538 Views
19 Pages

Abnormal and Changing Information Interaction in Adults with Attention-Deficit/Hyperactivity Disorder Based on Network Motifs

  • Xubin Wu,
  • Yuxiang Guo,
  • Jiayue Xue,
  • Yanqing Dong,
  • Yumeng Sun,
  • Bin Wang,
  • Jie Xiang and
  • Yi Liu

15 September 2023

Network motif analysis approaches provide insights into the complexity of the brain’s functional network. In recent years, attention-deficit/hyperactivity disorder (ADHD) has been reported to result in abnormal information interactions in macro...

  • Review
  • Open Access
13 Citations
6,545 Views
19 Pages

Protein–Protein Interaction (PPI) Network of Zebrafish Oestrogen Receptors: A Bioinformatics Workflow

  • Rabiatul-Adawiah Zainal-Abidin,
  • Nor Afiqah-Aleng,
  • Muhammad-Redha Abdullah-Zawawi,
  • Sarahani Harun and
  • Zeti-Azura Mohamed-Hussein

27 April 2022

Protein–protein interaction (PPI) is involved in every biological process that occurs within an organism. The understanding of PPI is essential for deciphering the cellular behaviours in a particular organism. The experimental data from PPI met...

  • Article
  • Open Access
4 Citations
4,192 Views
19 Pages

Human–object interaction (HOI) detection is important for promoting the development of many fields such as human–computer interactions, service robotics, and video security surveillance. A high percentage of human–object pairs with...

  • Article
  • Open Access
23 Citations
13,092 Views
24 Pages

1 December 2014

Using three spatial network measures of “space syntax”, this correlational study describes four interaction-related behaviors among three groups of users in relation to visibility and accessibility of spaces in four adult intensive care units (ICUs)...

  • Article
  • Open Access
1 Citations
3,035 Views
13 Pages

Recognizing and segmenting surgical workflow is important for assessing surgical skills as well as hospital effectiveness, and plays a crucial role in maintaining and improving surgical and healthcare systems. Most evidence supporting this remains si...

  • Article
  • Open Access
6 Citations
4,090 Views
12 Pages

Network Protein Interaction in the Link between Stroke and Periodontitis Interplay: A Pilot Bioinformatic Analysis

  • Yago Leira,
  • Paulo Mascarenhas,
  • Juan Blanco,
  • Tomás Sobrino,
  • José João Mendes,
  • Vanessa Machado and
  • João Botelho

20 May 2021

The clinical interaction between stroke and periodontitis has been consistently studied and confirmed. Hence, exploring potentially new protein interactions in this association using bioinformatic strategies presents potential interest. In this explo...

  • Article
  • Open Access
25 Citations
6,460 Views
24 Pages

14 December 2019

Host proteins that are central to infection of potyviruses (genus Potyvirus; family Potyviridae) include the eukaryotic translation initiation factors eIF4E and eIF(iso)4E. The potyviral genome-linked protein (VPg) and the helper component proteinase...

  • Article
  • Open Access
35 Citations
4,496 Views
15 Pages

MCN-CPI: Multiscale Convolutional Network for Compound–Protein Interaction Prediction

  • Shuang Wang,
  • Mingjian Jiang,
  • Shugang Zhang,
  • Xiaofeng Wang,
  • Qing Yuan,
  • Zhiqiang Wei and
  • Zhen Li

29 July 2021

In the process of drug discovery, identifying the interaction between the protein and the novel compound plays an important role. With the development of technology, deep learning methods have shown excellent performance in various situations. Howeve...

  • Article
  • Open Access
10 Citations
5,089 Views
19 Pages

16 January 2021

Consumer-to-consumer interaction is an important activity in network communities. Consumer-to-consumer interaction involves information interaction and social interaction, which greatly influences consumers’ experience and behaviors. The model...

  • Article
  • Open Access
1 Citations
1,673 Views
16 Pages

Reconstruction of Metabolic–Protein Interaction Integrated Network of Eriocheir sinensis and Analysis of Ecdysone Synthesis

  • Tong Hao,
  • Zhentao Song,
  • Mingzhi Zhang,
  • Lingrui Zhang,
  • Jiarui Yang,
  • Jingjing Li and
  • Jinsheng Sun

26 March 2024

Integrated networks have become a new interest in genome-scale network research due to their ability to comprehensively reflect and analyze the molecular processes in cells. Currently, none of the integrated networks have been reported for higher org...

  • Article
  • Open Access
1 Citations
2,852 Views
17 Pages

Gaze Estimation Network Based on Multi-Head Attention, Fusion, and Interaction

  • Changli Li,
  • Fangfang Li,
  • Kao Zhang,
  • Nenglun Chen and
  • Zhigeng Pan

18 March 2025

Gaze is an externally observable indicator of human visual attention, and thus, recording the gaze position can help to solve many problems. Existing gaze estimation models typically utilize separate neural network branches to process data streams fr...

  • Article
  • Open Access
8 Citations
2,953 Views
21 Pages

A Multiscale Cross Interaction Attention Network for Hyperspectral Image Classification

  • Dongxu Liu,
  • Yirui Wang,
  • Peixun Liu,
  • Qingqing Li,
  • Hang Yang,
  • Dianbing Chen,
  • Zhichao Liu and
  • Guangliang Han

10 January 2023

Convolutional neural networks (CNNs) have demonstrated impressive performance and have been broadly applied in hyperspectral image (HSI) classification. However, two challenging problems still exist: the first challenge is that redundant information...

  • Article
  • Open Access
30 Citations
5,466 Views
17 Pages

Genome-wide association studies (GWAS) can be used to infer genome intervals that are involved in genetic diseases. However, investigating a large number of putative mutations for GWAS is resource- and time-intensive. Network-based computational appr...

  • Article
  • Open Access
6 Citations
1,666 Views
17 Pages

9 June 2023

Adaptive interactions are an important property of many real-word network systems. A feature of such networks is the change in their connectivity depending on the current states of the interacting elements. In this work, we study the question of how...

  • Article
  • Open Access
5 Citations
2,431 Views
14 Pages

Identifying Network Biomarkers in Early Diagnosis of Hepatocellular Carcinoma via miRNA–Gene Interaction Network Analysis

  • Zhiyuan Yang,
  • Yuanyuan Qi,
  • Yijing Wang,
  • Xiangyun Chen,
  • Yuerong Wang and
  • Xiaoli Zhang

10 September 2023

Background: Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer at the histological level. Despite the emergence of new biological technology, advanced-stage HCC remains largely incurable. The prediction of a cancer biomarker is a key pro...

  • Article
  • Open Access
7 Citations
2,364 Views
17 Pages

29 August 2022

It is of great significance to estimate the interaction force of upper limbs accurately for improving the control performance of human–computer interaction. However, due to the randomness of the input biological signals and the influence of env...

  • Article
  • Open Access
3,392 Views
15 Pages

7 April 2022

Creativity is becoming a necessary core competence in nearly all businesses today, and firms are striving to find ways to promote the creativity of employees. This study aimed to analyze the relationships between an individual actor’s network c...

  • Review
  • Open Access
36 Citations
6,879 Views
23 Pages

Two-component systems (TCS) in plants have evolved into a more complicated multi-step phosphorelay (MSP) pathway, which employs histidine kinases (HKs), histidine-containing phosphotransfer proteins (HPts), and response regulators (RRs) to regulate v...

  • Article
  • Open Access
7 Citations
2,963 Views
17 Pages

9 September 2023

The prediction of drug–target interaction (DTI) is crucial to drug discovery. Although the interactions between the drug and target can be accurately verified by traditional biochemical experiments, the determination of DTI through biochemical...

  • Article
  • Open Access
3 Citations
3,059 Views
11 Pages

Drug and Protein Interaction Network Construction for Drug Repurposing in Alzheimer’s Disease

  • Georgios N. Dimitrakopoulos,
  • Aristidis G. Vrahatis,
  • Themis P. Exarchos,
  • Marios G. Krokidis and
  • Panagiotis Vlamos

Alzheimer’s disease is one of the leading causes of death globally, significantly impacting countless families and communities. In parallel, recent advancements in molecular biology and network approaches, guided by the Network Medicine perspec...

  • Article
  • Open Access
13 Citations
4,869 Views
15 Pages

23 November 2020

Recent studies supported a clinical association between Parkinson’s disease (PD) and periodontitis. Hence, investigating possible interactions between proteins associated to these two conditions is of interest. In this study, we conducted a pro...

  • Article
  • Open Access
15 Citations
4,434 Views
20 Pages

A Robust Drug–Target Interaction Prediction Framework with Capsule Network and Transfer Learning

  • Yixian Huang,
  • Hsi-Yuan Huang,
  • Yigang Chen,
  • Yang-Chi-Dung Lin,
  • Lantian Yao,
  • Tianxiu Lin,
  • Junlin Leng,
  • Yuan Chang,
  • Yuntian Zhang and
  • Hsien-Da Huang
  • + 3 authors

14 September 2023

Drug–target interactions (DTIs) are considered a crucial component of drug design and drug discovery. To date, many computational methods were developed for drug–target interactions, but they are insufficiently informative for accurately...

  • Article
  • Open Access
8 Citations
2,673 Views
21 Pages

21 August 2022

Recently, with the rapid development of deep learning (DL), an increasing number of DL-based methods are applied in pansharpening. Benefiting from the powerful feature extraction capability of deep learning, DL-based methods have achieved state-of-th...

  • Article
  • Open Access
10 Citations
3,542 Views
15 Pages

Interaction Network of Porcine Circovirus Type 3 and 4 Capsids with Host Proteins

  • Jianwei Zhou,
  • Yongxia Wang,
  • Linyi Zhou,
  • Yonghui Qiu,
  • Jie Zhao,
  • Beining Dai,
  • Xufei Feng,
  • Lei Hou and
  • Jue Liu

29 April 2022

An extensive understanding of the interactions between host cellular and viral proteins provides clues for studying novel antiviral strategies. Porcine circovirus type 3 (PCV3) and type 4 (PCV4) have recently been identified as viruses that can poten...

  • Article
  • Open Access
17 Citations
4,784 Views
19 Pages

A Novel Deep Neural Network Technique for Drug–Target Interaction

  • Jackson G. de Souza,
  • Marcelo A. C. Fernandes and
  • Raquel de Melo Barbosa

Drug discovery (DD) is a time-consuming and expensive process. Thus, the industry employs strategies such as drug repositioning and drug repurposing, which allows the application of already approved drugs to treat a different disease, as occurred in...

  • Article
  • Open Access
27 Citations
5,417 Views
19 Pages

Grouting Process Simulation Based on 3D Fracture Network Considering Fluid–Structure Interaction

  • Yushan Zhu,
  • Xiaoling Wang,
  • Shaohui Deng,
  • Wenlong Chen,
  • Zuzhi Shi,
  • Linli Xue and
  • Mingming Lv

15 February 2019

Grouting has always been the main engineering measure of ground improvement and foundation remediation of hydraulic structures. Due to complex geological conditions and the interactions between the grout and the fractured rock mass, which poses a ser...

  • Article
  • Open Access
1 Citations
3,231 Views
15 Pages

15 April 2025

Traditional centralized network structures exhibit clear scalability and communication efficiency bottlenecks. This paper proposes a solution based on a bidirectional unweighted heterogeneous graph, Dynamic Nexus Mesh Communication, designed to impro...

  • Article
  • Open Access
1,774 Views
23 Pages

Analysis of Offshore Pile–Soil Interaction Using Artificial Neural Network

  • Peiyuan Lin,
  • Kun Li,
  • Xiangwei Yu,
  • Tong Liu,
  • Xun Yuan and
  • Haoyi Li

Offshore wind power is one of the primary forms of utilizing marine green energy in China. Currently, near-shore wind power predominantly employs monopile foundations, with designs typically being overly conservative, resulting in high construction c...

  • Article
  • Open Access
22 Citations
6,030 Views
21 Pages

17 August 2019

Interaction forces are traditionally predicted by a contact type haptic sensor. In this paper, we propose a novel and practical method for inferring the interaction forces between two objects based only on video data—one of the non-contact type...

  • Article
  • Open Access
39 Citations
6,431 Views
14 Pages

21 February 2022

Concurrent use of multiple drugs can lead to unexpected adverse drug reactions. The interaction between drugs can be confirmed by routine in vitro and clinical trials. However, it is difficult to test the drug–drug interactions widely and effec...

  • Article
  • Open Access
1 Citations
2,285 Views
11 Pages

Pantograph–Catenary Interaction Prediction Model Based on SCSA-RBF Network

  • Mengzhen Wu,
  • Xianghong Xu,
  • Haochen Zhang,
  • Rui Zhou and
  • Jianshan Wang

4 January 2024

As a traditional numerical simulation method for pantograph–catenary interaction research, the pantograph–catenary finite element model cannot be applied to the real-time monitoring of pantograph–catenary contact force, and the comp...

  • Article
  • Open Access
36 Citations
7,560 Views
18 Pages

Mapping Entrepreneurs’ Orientation towards Sustainability in Interaction versus Network Marketing Practices

  • Elena-Mădălina Vătămănescu,
  • Patrizia Gazzola,
  • Violeta Mihaela Dincă and
  • Roberta Pezzetti

6 September 2017

By gliding sustainability into the mainstream areas of marketing strategy, the purpose of the current research is to analyze the influence of the entrepreneurs’ orientation towards sustainability on relational marketing practices—i.e., interaction ve...

  • Article
  • Open Access
2 Citations
1,329 Views
17 Pages

25 April 2025

(1) Background: Circular RNAs (circRNAs) are covalently closed single-stranded molecules that play crucial roles in gene regulation, while microRNAs (miRNAs), specifically mature microRNAs, are naturally occurring small molecules of non-coding RNA wi...

  • Article
  • Open Access
1 Citations
1,169 Views
15 Pages

13 March 2025

Improving the performance of human–computer interaction systems is an essential indicator of aircraft intelligence. To address the limitations of single-modal interaction methods, a multimodal interaction model based on gaze and EEG target sele...

  • Article
  • Open Access
1,009 Views
31 Pages

CSGI-Net: A Cross-Sample Graph Interaction Network for Multimodal Sentiment Analysis

  • Erlin Tian,
  • Shuai Zhao,
  • Zuhe Li,
  • Haoran Chen,
  • Yifan Gao and
  • Yushan Pan

31 August 2025

With the widespread application of multimodal data in sentiment analysis, effectively integrating information from different modalities to improve the accuracy and robustness of sentiment analysis has become a critical issue. Although current fusion...

  • Article
  • Open Access
15 Citations
4,772 Views
17 Pages

Construction, Identification and Analysis of the Interaction Network of African Swine Fever Virus MGF360-9L with Host Proteins

  • Bo Yang,
  • Dajun Zhang,
  • Xijuan Shi,
  • Chaochao Shen,
  • Yu Hao,
  • Ting Zhang,
  • Jinke Yang,
  • Xingguo Yuan,
  • Xuehui Chen and
  • Xiangtao Liu
  • + 7 authors

10 September 2021

African swine fever virus (ASFV) is prevalent in many countries and is a contagious and lethal virus that infects pigs, posing a threat to the global pig industry and public health. The interaction between the virus and the host is key to unlocking t...

  • Article
  • Open Access
7 Citations
5,458 Views
32 Pages

Coronavirus disease 2019 (COVID-19) is still an active global public health issue. Although vaccines and therapeutic options are available, some patients experience severe conditions and need critical care support. Hence, identifying key genes or pro...

  • Article
  • Open Access
250 Views
22 Pages

MBFI-Net: Multi-Branch Feature Interaction Network for Semantic Change Detection

  • Qing Ding,
  • Fengyan Wang,
  • Kaiyuan Sun,
  • Weilong Chen,
  • Mingchang Wang and
  • Gui Cheng

5 January 2026

Semantic change detection (SCD) effectively captures ground object transition information within change regions, delivering more comprehensive and detailed results than binary change detection (BCD) tasks. The existing multi-task SCD models enable pa...

of 323