339 Results Found

In pediatric surgery, robotic technology is useful. However, it is difficult to apply this technology due to size-related problems. In our study, we proposed a mechanical design method using a human-in-the-loop type simulator, and the moving volume a...

Convolutional neural networks have demonstrated excellent performance in oral cancer detection and classification. However, the end-to-end learning strategy makes CNNs hard to interpret, and it can be challenging to fully understand the decision-maki...

Intrusion detection systems (IDSs) must operate under severe class imbalance, evolving attack behavior, and the need for calibrated decisions that integrate smoothly with security operations. We propose a human-in-the-loop IDS that combines a convolu...

Multibody modeling of mechanical systems can be applied to various applications. Human-in-the-loop interfaces represent a growing research field, for which increasingly more devices include a dynamic multibody model to emulate the system physics in r...

The digitization of manufacturing industry has led to leaner and more efficient production, under the Industry 4.0 concept. Nowadays, datasets collected from shop floor assets and information technology (IT) systems are used in data-driven analytics...

Cell classification based on histopathology images is crucial for tumor recognition and cancer diagnosis. Using deep learning, classification accuracy is hugely improved. Semi-supervised learning is an advanced deep learning approach that uses both l...

The working hypothesis in this project is that gaze interactions play a central role in structuring the joint control and guidance strategy of the human operator performing spatial tasks. Perceptual guidance and control is the idea that the visual an...

The ankle joint is one of the important joints of the human body to maintain the ability to walk. Diseases such as stroke and ankle osteoarthritis could weaken the body’s ability to control joints, causing people’s gait to be out of balan...

In recent years, physiological features have gained more attention in developing models of personal thermal comfort for improved and accurate adaptive operation of Human-In-The-Loop (HITL) Heating, Ventilation, and Air-Conditioning (HVAC) systems. Pu...

The use of aerial robots for inspection and maintenance in industrial settings demands high maneuverability, precise control, and reliable measurements. This study explores the development of a fully customized unmanned aerial manipulator (UAM), comp...

In the era of Big Data, entity resolution (ER), i.e., the process of identifying which records refer to the same entity in the real world, plays a critical role in data-integration tasks, especially in mission-critical applications where accuracy is...

The human-in-the-loop technology requires studies on sensory-motor characteristics of each hand for an effective human–robot collaboration. This study aims to investigate the differences in visuomotor control between the dominant (DH) and non-d...

Algorithms for locomotion mode recognition (LMR) based on surface electromyography and mechanical sensors have recently been developed and could be used for the neural control of powered prosthetic legs. However, the variations in input signals, caus...

Precision agriculture increasingly recognizes the transformative potential of unmanned aerial systems (UASs) for crop monitoring and field assessment, yet research consistently highlights significant usability barriers as the main constraints to wide...

Percutaneous interventions via minimally invasive surgical systems can provide patients with better outcomes and faster recovery times than open surgeries. Accurate needle insertions are vital for successful procedures, and actively steered needles c...

In histopathological image segmentation, existing methods often show low sensitivity to small lesions and indistinct boundaries, leading to missed detections. Since, in clinical diagnosis, the consequences of missed detection are more serious than fa...

Small object detection in traffic scenes presents unique challenges for mobile robots operating under constrained computational resources and highly dynamic environments. Unlike general object detection, small targets often suffer from low resolution...

Large language models (LLMs) and other foundation models are rapidly being woven into enterprise analytics workflows, where they assist with data exploration, forecasting, decision support, and automation. These systems can feel like powerful new tea...

Generative AI enables personalized computer science education at scale, yet questions remain about whether such personalization supports or undermines learning. This scoping review synthesizes 32 studies (2023–2025) purposively sampled from 259...

Prompt engineering (PE) has emerged as a transformative paradigm in software engineering (SE), leveraging large language models (LLMs) to support a wide range of SE tasks, including code generation, bug detection, and software traceability. This stud...

Deep neural networks must address the dual challenge of delivering high-accuracy predictions and providing user-friendly explanations. While deep models are widely used in the field of time series modeling, deciphering the core principles that govern...

The intersection of Artificial Intelligence (AI) and education is revolutionizing learning and teaching in this digital era, with Generative AI and large language models (LLMs) providing even greater possibilities for the future. The digital transfor...

Telomeric repeat containing RNA (TERRA) is transcribed from subtelomeric regions to telomeres. TERRA RNA can invade telomeric dsDNA and form telomeric R-loop structures. A growing body of evidence suggests that TERRA-mediated R-loops are critical pla...

Background/Objectives: One-carbon metabolism is a critical pathway for epigenetic mechanisms. Circulating biomarkers of one-carbon metabolism have been associated with changes in nuclear DNA methylation levels in individuals affected by age-related d...

Flap endonuclease 1 (FEN1) is an essential enzyme that removes RNA primers and base lesions during DNA lagging strand maturation and long-patch base excision repair (BER). It plays a crucial role in maintaining genome stability and integrity. FEN1 is...

Human immunodeficiency virus-1 (HIV-1) recognizes one of its principal coreceptors, CXC chemokine receptor 4 (CXCR4), on the host cell via the third variable loop (V3 loop) of HIV-1 envelope glycoprotein gp120 during the viral entry process. Here, th...

Lower body negative pressure (LBNP) has been implemented as a tool to simulate systemic effects of hypovolemia, understand orthostatic challenges and study G load stress in humans. However, the exact hemodynamic mechanisms of graded LBNP followed by...

Arginase catalyzes the hydrolysis of L-arginine into L-ornithine and urea. This enzyme has several analogies with agmatinase, which catalyzes the hydrolysis of agmatine into putrescine and urea. However, this contrasts with the highlighted specificit...

Well-being has become an important policy goal to replace gross domestic product (GDP) as an indicator of national progress. Several multidimensional metrics and indicators of well-being have been developed mostly based on the four-capital model that...

Human genomic DNA contains a number of diverse repetitive sequence motifs, often identified as fragile sites leading to genetic instability. Among them, expansion events occurring at triplet repeats have been extensively studied due to their associat...

Human T-cell leukemia virus type 1 (HTLV-1) is a human delta retrovirus that causes adult T-cell leukemia/lymphoma (ATL) in 3–5% of the infected population after decades of clinical latency. HTLV-1 Tax is a potent activator of IKK/NF-κB a...

The activity of β-ureidopropionase, which catalyses the last step in the degradation of uracil, thymine, and analogous antimetabolites, is cooperatively regulated by the substrate and product of the reaction. This involves shifts in the equilibr...

Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication. Th...

This article proposes a distributed formation control strategy for mobile robots (using TurtleBot3 Burger platforms) based on teleoperation using artificial forces and mechanical impedance modeling. The proposed control law is structured in cascade,...

Protein kinase CK2 has been considered as an attractive therapeutic target of cancer therapy. The tricyclic quinoline compound CX-4945 is the first representative of CK2 inhibitors used in human clinical trials. The binding of non-2,6-naphtyridine su...

The rapid development of wearable technologies is increasing research interest in on-body robotics, where relocatable robots can serve as haptic interfaces, support healthcare measurements, or assist with daily activities. However, on-body mobile rob...

This paper aims to examine the relationship between organisational learning and ESG (environmental, social, and governance) performance. The PRISMA protocol was followed by full-text reading 57 peer-reviewed academic journal articles published in dif...

The textile and clothing industry generates much pollution and consumes a large amount of resources. Improper uses and disposal of clothing products make the problems much more severe. Fast fashion products shorten the valid lifecycle and generate mo...

Zinc transporters take up/release zinc ions (Zn2+) across biological membranes and maintain intracellular and intra-organellar Zn2+ homeostasis. Since this process requires a series of conformational changes in the transporters, detailed information...

Adenovirus (AdV) infection elicits a strong immune response with the production of neutralizing antibodies and opsonization by complement and coagulation factors. One anti-hexon neutralizing antibody, called 9C12, is known to activate the complement...

Terminal deoxynucleotidyl transferase (TdT) is a unique DNA polymerase that catalyzes template-independent nucleotide addition at the 3′-end of DNA, playing a critical role in generating immune receptor diversity. While the structural importanc...

Even though the rhythmic oscillations of life have long been known, the precise molecular mechanisms of the biological clock are only recently being explored. Circadian rhythms are found in virtually all organisms and affect our lives. Thus, it is no...

Human β2-microglobulin (b2m) protein is classically associated with dialysis-related amyloidosis (DRA). Recently, the single point mutant D76N was identified as the causative agent of a hereditary systemic amyloidosis affecting visceral organs....

This paper presents an intelligent bio-inspired cooperative decoupling control strategy (IBICDC) for the problems of modeling difficulties and strong coupling in the marine boiler-turbine system (MBTS). First, the model of the main steam pressure con...

Flavin adenine dinucleotide synthetases (FADSs) catalyze FAD biosynthesis through two consecutive catalytic reactions, riboflavin (RF) phosphorylation and flavin mononucleotide (FMN) adenylylation. Bacterial FADSs have RF kinase (RFK) and FMN adenyly...

The article describes the rationale for inhibition of the renin-angiotensin system (RAS) pathways as specific targets in patients infected by SARS-CoV-2 in order to prevent positive feedback-loop mechanisms. Based purely on experimental studies in wh...

Properly organizing DNA within the nucleus is critical to ensure normal downstream nuclear functions. CTCF and cohesin act as major architectural proteins, working in concert to generate thousands of high-intensity chromatin loops. Due to their centr...

The emergence of collaborative robotics has had a great impact on the development of robotic solutions for cooperative tasks nowadays carried out by humans, especially in industrial environments where robots can act as assistants to operators. Even s...

To overcome the deficiencies of the traditional open-loop cognition method, which lacks evaluation of the cognitive results, a novel cognitive method for greengage grading based on dynamic feature and ensemble networks is explored in this paper. Firs...

Structural maintenance of chromosomes (SMC) complexes play a crucial role in organizing the three-dimensional structure of chromatin, facilitating key processes such as gene regulation, DNA repair, and chromosome segregation. This review explores the...