40,853 Results Found

The origin and evolution of genes are central themes in evolutionary biology and genomics, shedding light on how molecular innovations shape biological complexity and adaptation. This review explores the principal mechanisms underlying gene emergence...

Topologically associating domains (TADs) are the structural and functional units of the genome. However, the functions of protein-coding genes existing in the same or different TADs have not been fully investigated. We compared the functional similar...

Brassinosteroids (BRs) play important regulatory roles in plant growth and development, with functional BR receptors being crucial for BR recognition or signaling. Although functional BR receptors have been extensively studied in herbaceous plants, t...

The development of severe COVID-19, which is a complex multisystem disease, is thought to be associated with many genes whose action is modulated by numerous environmental and genetic factors. In this study, we focused on the ideas of the omnigenic m...

Penaeus monodon is one of the world’s most important aquaculture species, with its host-associated microbial community playing a crucial role in its growth, metabolism, immune response, and adaptation. In our study, we utilized Illumina high-th...

Different revegetatiom types can affect the chemical composition of soil organic carbon (SOC), soil microbial community and the functional genes related to carbon cycle. However, the relationships between SOC chemical functional groups and soil micro...

The product innovation design is an innovation-intensive process that requires abundant knowledge and design experience, even across industries and disciplines, as a resource for problem solving. Therefore, designers need to have a good command of mo...

In plants, alternative splicing (AS) is a crucial post-transcriptional regulatory mechanism that generates diverse mature transcripts from precursor mRNA, with the resulting functional proteins regulating a wide range of plant life activities. The re...

The OVATE gene family is a class of conserved transcription factors that play significant roles in plant growth, development, and abiotic stress, and also affect fruit shape in vegetable crops. Bottle gourd (Lagenaria siceraria), commonly known as ca...

Members of AP1/FUL subfamily genes play an essential role in the regulation of floral meristem transition, floral organ identity, and fruit ripping. At present, there have been insufficient studies to explain the function of the AP1/FUL-like subfamil...

Soil pH critically regulates microbial community structure and activity, thereby influencing carbon transformation processes in terrestrial ecosystems. However, the mechanisms underlying pH-mediated shifts in microbial metabolic functions and cellulo...

Anaerobic ammonia oxidation (anammox) is considered an efficient and low-energy biological nitrogen removal process. However, there are limited studies addressing the changes in antibiotic resistance genes (ARGs) during the startup of an anammox reac...

Cryptomeria fortunei, also known as the Chinese cedar, is an important timber species in southern China. The primary component of its woody tissues is lignin, mainly present in secondary cell walls. Therefore, continuous lignin synthesis is crucial f...

Clubroot disease caused by Plasmodiophora brassicae has greatly affected the quality and yield of Chinese cabbage. Excavating the key resistance genes and verifying their function is important for clarifying disease resistance mechanisms. Virus-induc...

Traditional Chinese strong-aroma baijiu (CSAB) fermentation technology has been used for thousands of years. Microbial communities that are enriched in continuous and uninterrupted fermentation pits (FPs) are important for fermentation. However, chan...

Soil nitrogen (N) mineralization typically governs the availability and movement of soil N. Understanding how factors, especially functional genes, affect N transformations is essential for the protection and restoration of forest ecosystems. To unco...

Background: Primary open-angle glaucoma (POAG) is the most prevalent glaucoma subtype, but its exact etiology is still unknown. In this study, we aimed to prioritize the most likely ‘causal’ genes and identify functional characteristics a...

Rubisco activase (RCA) is an ATP-dependent enzyme that plays a crucial role in plant stress responses by regulating the catalytic activity of Rubisco. However, the alternative splicing and functional characteristics of the RCA gene exhibit notable sp...

Laccases (EC 1.10.3.2) have been widely considered to participate in the metabolic processes of lignin synthesis, osmotic stress response, and flavonoid oxidation in higher plants. The research into Populus trichocarpa laccase focused on the synthesi...

As one of the most diverse habitats of microorganisms, soil has been recognised as a reservoir of both antibiotics and the antibiotic resistance genes (ARGs). Bacteria naturally inhabiting soil or water often possess innate ARGs to counteract the che...

In recent years, pea aphids have become major pests of alfalfa. Our previous study found that “Gannong 5” is a highly aphid-resistant alfalfa variety and that “Lie Renhe” is a susceptible one. The average field susceptibility...

Proline, a critical osmoregulatory compound, is integral to various plant stress responses. The P5CS gene, which encodes the rate-limiting enzyme in proline biosynthesis, known as ∆1-pyrroline-5-carboxylate synthetase, is fundamental to these s...

Background/Objectives: GATA transcription factors play pivotal roles in regulating plant growth and development, physiological metabolism, and responses to environmental stress. However, research on GATA genes in sweetpotato remains limited. Methods:...

To investigate the effects of different manures in combination with fulvic acid on the abundance of N-cycling functional genes in greenhouse soils, Chinese cabbage was planted for three growing seasons. A total of six treatments—pig manure (P),...

Vitamin B6 is an essential coenzyme involved in various metabolic processes critical for plant growth and development. However, its biosynthesis and regulatory mechanisms remain poorly understood in the ancient gymnosperm Ginkgo biloba. In this study...

Microbial functional genes serve as the core genetic foundation driving microbial ecological functions; however, its microbial functional gene composition across varied habitats and its ecological adaptation interplay with plants remain understudied....

Improved reproductive efficiency could lead to economic benefits for the beef industry, once the intensive selection pressure has led to a decreased fertility. However, several factors limit our understanding of fertility traits, including genetic di...

Long-term fertilization profoundly influences soil biochemical processes and microbial functionality, yet the coupling mechanisms between soil enzyme activities and functional genes in nutrient cycling remain unclear. This study investigated the effe...

Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases. In AD patients, amyloid-β (Aβ) peptide-mediated degeneration of the cholinergic system utilizing acetylcholine (ACh) for memory acquisition is observed. Si...

The antioxidative enzyme ascorbate peroxidase (APX) exerts a critically important function through scavenging reactive oxygen species (ROS), alleviating oxidative damage in plants, and enhancing their tolerance to salinity. Here, we identified 28 CmA...

Interferon (IFN)-related DNA damage resistant signature (IRDS) genes are a subgroup of interferon-stimulated genes (ISGs) found upregulated in different cancer types, which promotes resistance to DNA damaging chemotherapy and radiotherapy. Along with...

The process of domestication, despite its short duration as it compared with the time scale of the natural evolutionary process, has caused rapid and substantial changes in the phenotype of domestic animal species. Nonetheless, the genetic mechanisms...

Antibiotic resistance genes (ARGs) in soil are considered to represent one of the largest environmental resistomes on our planet. As these genes can potentially be disseminated among microorganisms via horizontal gene transfer (HGT) and in some cases...

DNA repair processes are involved in both the onset and treatment efficacy of colorectal cancer (CRC). A change of a single nucleotide causing an amino acid substitution in the corresponding protein may alter the efficiency of DNA repair, thus modify...

Genetic variants affecting the regulation of gene expression are among the main causes of human diversity. The potential importance of regulatory polymorphisms is underscored by results from Genome Wide Association Studies, which have already implica...

Iron plays a key role in oxygen transport, hematopoiesis, and hypoxia adaptation. This study aimed to explore the dynamic response mechanism of the iron regulatory network and key genes in Duroc piglets. Eighteen weaned piglets were randomly divided...

Phosphorus is essential for crop growth, but excessive use of chemical fertilizers can lead to environmental issues. The incorporation of organic materials has the potential to enhance phosphorus availability and promote soil phosphorus cycling. This...

Water table fluctuation alters environment properties and n-alkane transformation, leading to shifts in the groundwater microbial community and functions. A diesel-contaminated aquifer column experiment of seasonal water table fluctuation was designe...

This study explores the effects of afforestation in infertile mountainous areas on soil microbial communities and functional nutrient cycling genes in young Cyclobalanopsis gilva forests, aiming to provide a scientific basis for promoting C. gilva gr...

As one of the largest gene families in plants, the Leucine-Rich Repeat Receptor-Like Kinase (LRR-RLK) genes are involved in important biological processes, such as plant growth and development and response to bio-/abiotic stresses. The rubber tree (H...

(1) Background: Tree peonies display extensive cultivar diversity due to widespread hybridization, resulting in a complex genetic architecture. This complexity complicates the selection of universal reference genes across different cultivars for qRT-...

In our research we analyzed a series of water quality parameters and conducted a metagenomic analysis of the microbial community in the Chishui River (in southwestern China), aiming to explore the microbial driving mechanisms of the phosphorus cycle...

Short rotation coppice (SRC) is increasingly being adopted for bioenergy production, pollution remediation and land restoration. However, its long-term effects on soil microbial communities are poorly characterized. Here, we studied soil microbial fu...

Excessive nitrogen (N) fertilization in rice systems has caused soil degradation and reduced N use efficiency. Green manure, especially Astragalus sinicus (Chinese milk vetch), provides a sustainable alternative, but the microbial and functional gene...

Fertilization regimes impact the carbon cycle processes in paddy soils. However, the effects of shifting fertilization regimes on the structure of microbial communities and functional genes involved in soil carbon (C)-cycling remain unclear. A long-t...

In most higher plants, sucrose is the significant form of carbohydrate for long-distance transportation. Sucrose transporters/sucrose carriers (SUTs/SUCs) are involved in the loading and unloading of sucrose in phloem and play an important role in th...

The β-glucosidases (BGLUs) of Glycoside Hydrolase Family 1 (GH1) exhibit essential functions in plant secondary metabolism and stress responses, mediated by their dual catalytic capabilities in hydrolysis and transglycosylation. This study ident...

Synechococcus plays a pivotal role in the marine biogeochemical cycle. Advances in isolation techniques and high-throughput sequencing have expanded our understanding of the diversity of the Synechococcus community. However, their genomic diversity,...

The quality of Coffee arabica L. beans, particularly the aroma, is a key determinant of commercial value. Fatty acids, as precursors of volatile aroma compounds, play a crucial role in this quality. Screening and identification of their related genes...

Nitrous oxide (N₂O), as one of the important greenhouse gases in the atmosphere, has a significant impact on global climate change. Its emissions are significantly regulated by land use changes, especially in ecologically fragile semi-arid areas. How...