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4,218 Results Found

  • Article
  • Open Access
5 Citations
3,958 Views
19 Pages

With the increase of fire problems of new energy vehicles (EVs), more and more attention has been paid to charging safety. Firstly, the charging safety problems and protection strategies in the power grid are summarized from the grid side, the chargi...

  • Article
  • Open Access
1 Citations
5,166 Views
23 Pages

12 July 2022

During the 740s in Japan, the emperor established Buddhist temples in nearly all the provinces, in which three Buddhist scriptures were chanted to avert natural disasters. Tōdaiji, in the recently constructed capital, was the head temple of a ne...

  • Article
  • Open Access
2 Citations
1,599 Views
22 Pages

Strengthening Early Childhood Protective Factors Through Safe and Supportive Classrooms: Findings from Jump Start + COVID Support

  • Ruby Natale,
  • Tara Kenworthy LaMarca,
  • Yue Pan,
  • Elizabeth Howe,
  • Yaray Agosto,
  • Rebecca J. Bulotsky-Shearer,
  • Sara M. St. George,
  • Tanha Rahman,
  • Carolina Velasquez and
  • Jason F. Jent

20 June 2025

Background/Objectives: Early care and education programs promote children’s social–emotional development, predicting later school success. The COVID-19 pandemic worsened an existing youth mental health crisis and increased teacher stress....

  • Article
  • Open Access
6 Citations
2,889 Views
12 Pages

The Protective Role of Apelin in the Early Stages of Diabetic Retinopathy

  • Jing Feng,
  • Weiqiang Yang,
  • Fuxiao Luan,
  • Fang Ma,
  • Yingjie Wang,
  • Yiquan Zhang,
  • Xuhui Liu,
  • Li Chen,
  • Xiaofeng Hu and
  • Yong Tao

24 November 2022

Diabetic retinopathy (DR) is one of the most common and serious microvascular complications of diabetes. Although current treatments can control the progression of DR to a certain extent, there is no effective treatment for early DR. Apart from vascu...

  • Review
  • Open Access
9 Citations
6,079 Views
23 Pages

2 August 2021

In Australia, residents can choose to remain to defend their property against bushfire but, since the 2009 Black Saturday bushfires, considerable emphasis is placed on leaving early, well in advance of a bushfire. However, many householders delay the...

  • Article
  • Open Access
4 Citations
2,334 Views
17 Pages

A Hybrid Protection Scheme for the Gait Analysis in Early Dementia Recognition

  • Francesco Castro,
  • Donato Impedovo and
  • Giuseppe Pirlo

19 December 2023

Human activity recognition (HAR) through gait analysis is a very promising research area for early detection of neurodegenerative diseases because gait abnormalities are typical symptoms of some neurodegenerative diseases, such as early dementia. Whi...

  • Article
  • Open Access
8 Citations
4,717 Views
15 Pages

18 April 2019

The aim of this research is to build an ecological early warning indicator system. Several complex and interlinked factors contribute to changes in the environmental quality of scenic areas. If changes in these factors can be monitored and controlled...

  • Article
  • Open Access
654 Views
37 Pages

12 January 2026

This article examines the relationship between jihād and the protection of non-Muslim places of worship in early Islam. Drawing primarily on Qurʾānic verses 22:39–41 and the Covenants of the Prophet, it employs a synchronically c...

  • Review
  • Open Access
712 Views
14 Pages

12 November 2025

Background/Objectives: This narrative review examines how developmentally appropriate safety and health education interventions in early childhood settings impact the incidence and severity of pediatric conditions requiring neurosurgical intervention...

  • Review
  • Open Access
970 Views
19 Pages

Background/Objective: Early hemodynamic instability in sepsis arises from endothelial dysfunction and vasoplegia before capillary leakage and organ failure occur. Albumin administration guided by serum concentration or shock criteria has not improved...

  • Article
  • Open Access
8 Citations
3,830 Views
14 Pages

Early and Solid Protection Afforded by the Thiverval Vaccine Provides Novel Vaccination Alternatives Against Classical Swine Fever Virus

  • Yaneysis Lamothe-Reyes,
  • José Alejandro Bohórquez,
  • Miaomiao Wang,
  • Mònica Alberch,
  • Marta Pérez-Simó,
  • Rosa Rosell and
  • Llilianne Ganges

Classical swine fever virus (CSFV) remains a challenge for the porcine industry. Inefficient vaccination programs in some endemic areas may have contributed to the emergence of low and moderate virulence CSFV variants. This work aimed to expand and u...

  • Article
  • Open Access
5 Citations
2,565 Views
12 Pages

Live Influenza Vaccine Provides Early Protection against Homologous and Heterologous Influenza and May Prevent Post-Influenza Pneumococcal Infections in Mice

  • Yulia Desheva,
  • Galina Leontieva,
  • Tatiana Kramskaya,
  • Igor Losev,
  • Andrey Rekstin,
  • Nadezhda Petkova,
  • Polina Kudar and
  • Alexander Suvorov

Influenza and S. pneumoniae infections are a significant cause of morbidity and mortality worldwide. Intranasal live influenza vaccine (LAIV) may prevent influenza-related bacterial complications. The objectives of the study are to estimate resistanc...

  • Article
  • Open Access
1,133 Views
12 Pages

Protection Against Transplacental Transmission of a Highly Virulent Classical Swine Fever Virus Two Weeks After Single-Dose FlagT4G Vaccination in Pregnant Sows

  • Liani Coronado,
  • Àlex Cobos,
  • Adriana Muñoz-Aguilera,
  • Sara Puente-Marin,
  • Gemma Guevara,
  • Cristina Riquelme,
  • Saray Heredia,
  • Manuel V. Borca and
  • Llilianne Ganges

28 July 2025

Background/Objectives: Classical swine fever (CSF) continues to challenge global eradication efforts, particularly in endemic regions, where pregnant sows face heightened risks of vertical transmission following exposure to CSFV. Methods: This study...

  • Article
  • Open Access
1 Citations
896 Views
16 Pages

Research on Active Defense System for Transformer Early Fault Based on Fiber Leakage Magnetic Field Measurement

  • Junchao Wang,
  • Yaqi Liu,
  • Jian Mao,
  • Shaoyong Liu,
  • Zhixiang Tong,
  • Xiangli Deng and
  • Wenbin Tan

24 August 2025

In the early faults of transformer windings, there are obvious variation characteristics of the spatial leakage magnetic field. Taking the leakage magnetic field as the fault characteristic quantity can establish an active defense system for transfor...

  • Article
  • Open Access
17 Citations
5,159 Views
11 Pages

Porvac® Subunit Vaccine E2-CD154 Induces Remarkable Rapid Protection against Classical Swine Fever Virus

  • Yusmel Sordo-Puga,
  • Marisela Suárez-Pedroso,
  • Paula Naranjo-Valdéz,
  • Danny Pérez-Pérez,
  • Elaine Santana-Rodríguez,
  • Talia Sardinas-Gonzalez,
  • Mary Karla Mendez-Orta,
  • Carlos A. Duarte-Cano,
  • Mario Pablo Estrada-Garcia and
  • María Pilar Rodríguez-Moltó

17 February 2021

Live attenuated C-strain classical swine fever vaccines provide early onset protection. These vaccines confer effective protection against the disease at 5–7 days post-vaccination. It was previously reported that intramuscular administration of the P...

  • Article
  • Open Access
27 Citations
2,928 Views
20 Pages

21 August 2023

The Yellow River Source Area is located in the ecological protection and restoration area of the Sanjiangyuan in China, which has been deteriorating as a result of human-caused overgrazing and the grassland destruction caused by plateau rats and rabb...

  • Article
  • Open Access
7 Citations
3,249 Views
12 Pages

28 February 2021

Social and cultural sustainability is outlined as creating surroundings that include and stimulate positive interactions, such as promoting a sense of community and a feeling of belonging to a community, by being safe and attached to the local area....

  • Article
  • Open Access
7 Citations
3,795 Views
11 Pages

17 January 2019

In this study, the actual anti-biofouling (AF) efficacy of three protective coatings, including a chlorinated rubber-based coating (C0) and two polydimethylsiloxane (PDMS)-based coatings (P0 and PF), were estimated via the static field exposure assay...

  • Article
  • Open Access
12 Citations
3,502 Views
18 Pages

During the charging process of the electric vehicle (EV), a spontaneous combustion accident may occur due to overheating of the battery, causing personal danger and property damage. To address the charging safety of EVs, this paper proposes a new hyb...

  • Proceeding Paper
  • Open Access
2,418 Views
5 Pages

Design of a Smart Early Warning Hydrometeorological System: The Easy Project in Ermionida

  • Angelos Chasiotis,
  • Stefanos Chasiotis,
  • Christos Theodorakis,
  • Maria Bousdeki,
  • Elissavet Feloni and
  • Panagiotis T. Nastos

Climate change is linked to a higher risk of hydrometeorological disasters, which are driven by both the increased global surface temperature, which leads to more frequent droughts, and heavy rainfall events inducing floods. The Municipality of Ermio...

  • Article
  • Open Access
1,549 Views
31 Pages

Early Administration of N-Acetylcysteine Provides Renal and Cardiac Mitochondrial and Redox Protection, Preventing the Development of Cardio-Renal Syndrome Type IV Induced by 5/6NX

  • Karen Peralta-Buendía,
  • Belén Cuevas-López,
  • Fernando E. García-Arroyo,
  • Miriam Díaz-Rojas,
  • Juan Carlos León-Contreras,
  • Alejandro Silva-Palacios,
  • Guillermo Gonzaga,
  • Edilia Tapia,
  • Emma Saavedra and
  • Omar Emiliano Aparicio-Trejo
  • + 3 authors

16 October 2025

Chronic kidney disease (CKD) cardiac impairment is manifested as cardio-renal syndrome type 4 (CRS-IV). The kidneys and heart are highly dependent on mitochondria; thus, bioenergetics and redox and biogenesis alterations are critical in CKD and heart...

  • Article
  • Open Access
6 Citations
2,141 Views
23 Pages

15 April 2025

The early detection of faults in power transformers is crucial for ensuring operational reliability and minimizing system disruptions. This study introduces a novel machine learning framework that integrates Particle Swarm Optimization (PSO) and Dwar...

  • Article
  • Open Access
16 Citations
6,140 Views
27 Pages

Design of a Forest Fire Early Alert System through a Deep 3D-CNN Structure and a WRF-CNN Bias Correction

  • Alejandro Casallas,
  • Camila Jiménez-Saenz,
  • Victor Torres,
  • Miguel Quirama-Aguilar,
  • Augusto Lizcano,
  • Ellie Anne Lopez-Barrera,
  • Camilo Ferro,
  • Nathalia Celis and
  • Ricardo Arenas

14 November 2022

Throughout the years, wildfires have negatively impacted ecological systems and urban areas. Hence, reinforcing territorial risk management strategies against wildfires is essential. In this study, we built an early alert system (EAS) with two differ...

  • Article
  • Open Access
10 Citations
5,011 Views
19 Pages

Novel Recombinant Newcastle Disease Virus-Based In Ovo Vaccines Bypass Maternal Immunity to Provide Full Protection from Early Virulent Challenge

  • Kiril M. Dimitrov,
  • Tonya L. Taylor,
  • Valerie C. Marcano,
  • Dawn Williams-Coplin,
  • Timothy L. Olivier,
  • Qingzhong Yu,
  • Robert M. Gogal,
  • David L. Suarez and
  • Claudio L. Afonso

15 October 2021

Newcastle disease (ND) is one of the most economically important poultry diseases. Despite intensive efforts with current vaccination programs, this disease still occurs worldwide, causing significant mortality even in vaccinated flocks. This has bee...

  • Brief Report
  • Open Access
10 Citations
2,577 Views
10 Pages

Mammalian Cell-Line-Expressed CD2v Protein of African Swine Fever Virus Provides Partial Protection against the HLJ/18 Strain in the Early Infection Stage

  • Rong-Hong Hua,
  • Jing Liu,
  • Shu-Jian Zhang,
  • Ren-Qiang Liu,
  • Xian-Feng Zhang,
  • Xi-Jun He,
  • Dong-Ming Zhao and
  • Zhi-Gao Bu

28 June 2023

A cell line expressing the CD2v protein of ASFV was generated. The efficient expression of CD2v protein was determined by immunofluorescence and Western blotting. The CD2v protein was Ni-affinity purified from the supernatant of cell cultures. The CD...

  • Article
  • Open Access
1 Citations
822 Views
18 Pages

This study aimed to analyze the spatiotemporal trends of the non-agriculturalization of cultivated land (NACL) and evaluate the effectiveness of land management strategies in Shaanxi Province, China. First, geostatistical analysis was conducted to ex...

  • Review
  • Open Access
15 Citations
3,686 Views
15 Pages

Aneurysmal rupture accounts for the majority of subarachnoid hemorrhage and is responsible for most cerebrovascular deaths with high mortality and morbidity. Initial hemorrhage severity and secondary brain injury due to early brain injury and delayed...

  • Article
  • Open Access
6 Citations
2,858 Views
18 Pages

5 November 2023

The vulnerability to coastal disasters resulting from storm surges and wave overtopping (WOT) during typhoon intrusions is significantly escalating due to rising sea levels. In particular, coastal seawalls constructed along the coast through engineer...

  • Article
  • Open Access
12 Citations
4,389 Views
23 Pages

Enhancing Transformer Protection: A Machine Learning Framework for Early Fault Detection

  • Mohammed Alenezi,
  • Fatih Anayi,
  • Michael Packianather and
  • Mokhtar Shouran

8 December 2024

The reliable operation of power transformers is essential for grid stability, yet existing fault detection methods often suffer from inaccuracies and high false alarm rates. This study introduces a machine learning framework leveraging voltage signal...

  • Review
  • Open Access
15 Citations
4,931 Views
13 Pages

10 April 2020

Late-onset sepsis (LOS) and other systemic bloodstream infections are notable causes of neonatal mortality, particularly in prematurely born very low birth weight infants. Breastfeeding in early life has numerous health benefits, impacting the health...

  • Article
  • Open Access
15 Citations
6,532 Views
32 Pages

Geomorphology-Based Analysis of Flood Critical Areas in Small Hilly Catchments for Civil Protection Purposes and Early Warning Systems: The Case of the Feltrino Stream and the Lanciano Urban Area (Abruzzo, Central Italy)

  • Tommaso Piacentini,
  • Cristiano Carabella,
  • Fausto Boccabella,
  • Silvia Ferrante,
  • Carlo Gregori,
  • Vania Mancinelli,
  • Alessandro Pacione,
  • Tommaso Pagliani and
  • Enrico Miccadei

7 August 2020

This work is based on a drainage basin-scale geomorphological investigation combined with flood modeling. It is focused on the assessment of flood critical areas for the implementation of a geomorphology-based urban Early Warning System (EWS) in the...

  • Article
  • Open Access
2,386 Views
22 Pages

30 August 2023

The eyes provide themselves with immune tolerance. Frequent skin inflammatory diseases in young blind people suggest, nonetheless, that the eyes instruct a systemic immune tolerance that benefits the whole body. We tested this premise by using delaye...

  • Article
  • Open Access
2,168 Views
21 Pages

Early-Stage IM Treatment with the Host-Derived Immunostimulant CPDI-02 Increases Curative Protection of Healthy Outbred Mice Against Subcutaneous Infection with Community-Acquired Methicillin-Resistant Staphylococcus aureus USA300

  • Jason P. Stewart,
  • Caleb M. Sandall,
  • Jacob E. Parriott,
  • Stephen M. Curran,
  • Russell J. McCulloh,
  • Donald R. Ronning,
  • Joy A. Phillips,
  • Robin Schroeder,
  • Christy Neel and
  • Joseph A. Vetro
  • + 5 authors

Background/Objectives: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) greatly complicates the treatment of skin and soft tissue infections (SSTI). It was previously found that subcutaneous (SQ) treatment with the mononuclear...

  • Review
  • Open Access
31 Citations
9,801 Views
27 Pages

Primary Psychosis: Risk and Protective Factors and Early Detection of the Onset

  • Claudio Brasso,
  • Benedetta Giordano,
  • Cristina Badino,
  • Silvio Bellino,
  • Paola Bozzatello,
  • Cristiana Montemagni and
  • Paola Rocca

19 November 2021

Primary psychosis, which includes schizophrenia and other psychoses not caused by other psychic or physical conditions, has a strong impact worldwide in terms of disability, suffering and costs. Consequently, improvement of strategies to reduce the i...

  • Article
  • Open Access
6 Citations
3,213 Views
16 Pages

The FlagT4G Vaccine Confers a Strong and Regulated Immunity and Early Virological Protection against Classical Swine Fever

  • José Alejandro Bohórquez,
  • Miaomiao Wang,
  • Ivan Díaz,
  • Mònica Alberch,
  • Marta Pérez-Simó,
  • Rosa Rosell,
  • Douglas P. Gladue,
  • Manuel V. Borca and
  • Llilianne Ganges

2 September 2022

Control of classical swine fever virus (CSFV) in endemic countries relies on vaccination, mostly using vaccines that do not allow for differentiation of vaccinated from infected animals (DIVA). FlagT4G vaccine is a novel candidate that confers robust...

  • Article
  • Open Access
2,658 Views
10 Pages

23 January 2024

In the diverse multiethnic setting of colonial New Spain, women faced challenges in separating themselves from marriages they considered unendurable. The Catholic Church, which exercised hegemony over definitions of marriage in the colony, controlled...

  • Article
  • Open Access
24 Citations
8,195 Views
11 Pages

Maintaining Traditions: A Qualitative Study of Early Childhood Caries Risk and Protective Factors in an Indigenous Community

  • Ana Levin,
  • Karen Sokal-Gutierrez,
  • Anita Hargrave,
  • Elizabeth Funsch and
  • Kristin S. Hoeft

In lower middle-income economies (LMIE), the nutrition transition from traditional diets to sugary foods and beverages has contributed to widespread early childhood dental caries. This qualitative study explores perceived risk and protective factors,...

  • Article
  • Open Access
5 Citations
3,181 Views
15 Pages

16 April 2022

This study used relevant industrial pollution emission data collected between 2004 and 2020 in northeastern China. It utilized the synthetic control method (SCM) and used entire county-level areas within the scope of the typical black land protection...

  • Article
  • Open Access
23 Citations
5,217 Views
29 Pages

Development of an Early Warning and Incident Response System for the Protection of Visitors from Natural Hazards in Important Outdoor Sites in Greece

  • Chrysostomos Psaroudakis,
  • Gavriil Xanthopoulos,
  • Dimitris Stavrakoudis,
  • Antonios Barnias,
  • Vassiliki Varela,
  • Ilias Gkotsis,
  • Anna Karvouniari,
  • Spyridon Agorgianitis,
  • Ioannis Chasiotis and
  • Ioannis Z. Gitas
  • + 5 authors

Safety in touristic destinations is of utmost importance since tourists’ preferences change frequently in response to emerging threats. Natural hazards are a significant risk and, as such, they need to be considered in the effort for safe tourism. Se...

  • Article
  • Open Access
1,009 Views
20 Pages

Differences in Glycoproteins and the Potential for Early Protection Using LAIV Based on Drift Variants of the A/H1N1pdm09 Influenza Virus

  • Yulia Desheva,
  • Irina Mayorova,
  • Andrey Rekstin,
  • Daniil Sokolovsky,
  • Polina Kudar,
  • Nina Kopylova,
  • Danila Guzenkov,
  • Darya Petrachkova,
  • Andrey Mamontov and
  • Irina Kiseleva
  • + 1 author

11 September 2025

Background/Objectives: Antigenic drift of influenza A(H1N1pdm09) viruses has led to periodic replacement of vaccine strains. Understanding how structural differences in glycoproteins influence immune protection is crucial for improving vaccine effect...

  • Article
  • Open Access
3 Citations
2,454 Views
14 Pages

B Cells Induce Early-Onset Maternal Inflammation to Protect against LPS-Induced Fetal Rejection

  • Gina Marie Uehre,
  • Svetlana Tchaikovski,
  • Atanas Ignatov,
  • Ana Claudia Zenclussen and
  • Mandy Busse

8 November 2023

The maternal balance between B regulatory (Breg) cells and inflammatory B cells is of central importance for protection against preterm birth (PTB). However, the impact of B cell signaling in early maternal and fetal immune responses on inflammatory...

  • Review
  • Open Access
43 Citations
7,881 Views
26 Pages

6 April 2022

Cardiac hypertrophy, initiated by a variety of physiological or pathological stimuli (hemodynamic or hormonal stimulation or infarction), is a critical early adaptive compensatory response of the heart. The structural basis of the progression from co...

  • Article
  • Open Access
1,047 Views
17 Pages

28 September 2025

Background: The current assessment method of the protective efficacy of adjuvanted vaccines remains slow and labor-intensive, hindered by prolonged immunization protocols and complex assays. Methods: To overcome this bottleneck, we demonstrate that e...

  • Article
  • Open Access
6 Citations
3,846 Views
13 Pages

Supplementation of Rumen-Protected Glucose Increased the Risk of Disturbance of Hepatic Metabolism in Early Postpartum Holstein Cows

  • ZhiYuan Ma,
  • LuoYun Fang,
  • Emilio Ungerfeld,
  • XiaoPeng Li,
  • ChuanShe Zhou,
  • ZhiLiang Tan,
  • LinShu Jiang and
  • XueFeng Han

26 February 2022

The dual stress of reduced feed intake and increased milk yield in dairy cows early postpartum results in a negative energy balance. Rumen-protected glucose (RPG) has been reported to replenish energy, increase milk yield, and improve gut health. How...

  • Article
  • Open Access
2 Citations
2,177 Views
18 Pages

Ephedra alata Seeds Confer Kidney Protection against Early Life Exposure to Acephate by Regulating Oxidative Insult and Activating Autophagy

  • Afoua Mufti,
  • Anouar Feriani,
  • María del Mar Contreras,
  • Saber Nehdi,
  • Najla Hfaeidh,
  • Nizar Tlili and
  • Abdel Halim Harrath

25 November 2023

The aim of the current work was to examine for the first time the nephropreventive capacity of Ephedra alata seed extract (E) against maternal exposure to acephate in rat offspring. The in vivo results revealed that E. alata supplementation for 28 da...

  • Article
  • Open Access
15 Citations
7,121 Views
15 Pages

The Influence of Sunlight Exposure and Sun Protecting Behaviours on Allergic Outcomes in Early Childhood

  • Kristina Rueter,
  • Anderson P. Jones,
  • Aris Siafarikas,
  • Paola Chivers,
  • Susan L. Prescott and
  • Debra J. Palmer

The dramatic rise in allergic disease has occurred in tandem with recent environmental changes and increasing indoor lifestyle culture. While multifactorial, one consistent allergy risk factor has been reduced sunlight exposure. However, vitamin D su...

  • Article
  • Open Access
34 Citations
10,097 Views
14 Pages

Traditional and online bullying are prevalent throughout adolescence. Given their negative consequences, it is necessary to seek protective factors to reduce or even prevent their detrimental effects in the mental health of adolescents before they be...

  • Article
  • Open Access
14 Citations
3,458 Views
28 Pages

Protective Effects of Early Caffeine Administration in Hyperoxia-Induced Neurotoxicity in the Juvenile Rat

  • Julia Heise,
  • Thomas Schmitz,
  • Christoph Bührer and
  • Stefanie Endesfelder

28 January 2023

High-risk preterm infants are affected by a higher incidence of cognitive developmental deficits due to the unavoidable risk factor of oxygen toxicity. Caffeine is known to have a protective effect in preventing bronchopulmonary dysplasia associated...

  • Article
  • Open Access
7 Citations
3,280 Views
15 Pages

The Effects of Early-Life Stress on Liver Transcriptomics and the Protective Role of EPA in a Mouse Model of Early-Life-Stress-Induced Adolescent Depression

  • Jinlan Zhao,
  • Lihong Ye,
  • Zuyi Liu,
  • Jiayi Wu,
  • Di Deng,
  • Lin An,
  • Shasha Bai,
  • Lei Yang,
  • Binjie Liu and
  • Rong Zhang
  • + 2 authors

23 August 2023

Early-life stress (ELS) was found to increase the risk of adolescent depression, and clinical evidence indicated that eicosapentaenoic acid (EPA) was decreased in patients with adolescent depression, but the underlying mechanisms are unclear. Here, w...

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