Skip to Content
You are currently on the new version of our website. Access the old version .

273 Results Found

  • Article
  • Open Access
2 Citations
3,887 Views
18 Pages

The Role of Diffusion Weighted MR Imaging in the Diagnosis of Tendon Injuries of the Ankle and Foot

  • Hasan Aydın,
  • Volkan Kızılgöz,
  • Önder Ersan and
  • Baki Hekimoğlu

20 February 2022

Background and objectives: Our aim is to determine the diagnostic performance and utility of Diffusion Weighted MR Imaging (DWI) against the routine Magnetic Resonance Imaging (MRI) for the evaluation of patients with tendon injuries of the ankle and...

  • Article
  • Open Access
1 Citations
3,265 Views
15 Pages

Diffusion-Weighted MR Imaging of the Thymus in Children with Non-Thymic Neoplasms

  • Sook Min Hwang,
  • Ji Eun Park,
  • So-Young Yoo,
  • Ji Hye Kim and ,
  • Sun-Young Baek,
  • Sung-Hoon Moon and
  • Tae Yeon Jeon
  • + 2 authors+ 0 author

13 December 2023

Purpose: To investigate the diffusion-weighted imaging (DWI) findings and apparent diffusion coefficient (ADC) value of the thymus in children under the age of 13 who have non-thymic neoplasms. Materials and Methods: From January 2021 to April 2023,...

(This article belongs to the Special Issue What's New in Diagnostic Radiological Imaging?)
  • Review
  • Open Access
12 Citations
6,817 Views
10 Pages

Emerging Utility of Applied Magnetic Resonance Imaging in the Management of Traumatic Brain Injury

  • Jeffrey Nadel,
  • Joseph Scott McNally,
  • Anthony DiGiorgio and
  • Ramesh Grandhi

14 February 2021

Traumatic brain injury (TBI) is a widespread and expensive problem globally. The standard diagnostic workup for new TBI includes obtaining a noncontrast computed tomography image of the head, which provides quick information on operative pathologies....

(This article belongs to the Section Neurosciences)
  • Article
  • Open Access
11 Citations
5,054 Views
9 Pages

Combined Diagnostic Accuracy of Diffusion and Perfusion MR Imaging to Differentiate Radiation-Induced Necrosis from Recurrence in Glioblastoma

  • Ankush Jajodia,
  • Varun Goel,
  • Jitin Goyal,
  • Nivedita Patnaik and ,
  • Jeevitesh Khoda,
  • Sunil Pasricha and
  • Munish Gairola
  • + 2 authors+ 0 author

We aimed to use quantitative values derived from perfusion and diffusion-weighted MR imaging (PWI and DWI) to differentiate radiation-induced necrosis (RIN) from tumor recurrence in Glioblastoma (GBM) and investigate the best parameters for improved...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
923 Views
23 Pages

Magnetic resonance imaging (MRI) has become the gold standard for evaluating brain injury and development in newborn infants, providing structural, metabolic, and functional information without ionizing radiation. This review comprehensively examines...

(This article belongs to the Special Issue Technological Advances in Neurorehabilitation)
  • Review
  • Open Access
19 Citations
5,363 Views
24 Pages

Physiological Imaging Methods for Evaluating Response to Immunotherapies in Glioblastomas

  • Sanjeev Chawla,
  • Vanessa Shehu,
  • Pradeep K. Gupta,
  • Kavindra Nath and
  • Harish Poptani

Glioblastoma (GBM) is the most malignant brain tumor in adults, with a dismal prognosis despite aggressive multi-modal therapy. Immunotherapy is currently being evaluated as an alternate treatment modality for recurrent GBMs in clinical trials. These...

(This article belongs to the Section Molecular Oncology)
  • Review
  • Open Access
1 Citations
2,085 Views
18 Pages

MR-Guided Radiotherapy in Oesophageal Cancer: From Principles to Practice—A Narrative Review

  • Su Chen Fong,
  • Eddie Lau,
  • David S. Liu,
  • Niall C. Tebbutt and ,
  • Richard Khor,
  • Trevor Leong,
  • David Williams,
  • Sergio Uribe and
  • Sweet Ping Ng
  • + 4 authors+ 0 author

Oesophageal cancer remains a significant global health burden with poor survival outcomes despite multimodal treatment. Recent advances in magnetic resonance imaging (MRI) have opened opportunities to improve radiotherapy delivery. This review examin...

  • Article
  • Open Access
11 Citations
3,363 Views
11 Pages

Diffusion Weighted Imaging in the Assessment of Tumor Grade in Endometrial Cancer Based on Intravoxel Incoherent Motion MRI

  • Evangelia G. Chryssou,
  • Georgios C. Manikis,
  • Georgios S. Ioannidis,
  • Vrettos Chaniotis and ,
  • Thomas Vrekoussis,
  • Thomas G. Maris,
  • Kostas Marias and
  • Apostolos H. Karantanas
  • + 3 authors+ 0 author

The aim of this study is to investigate the possibility of predicting histological grade in patients with endometrial cancer on the basis of intravoxel incoherent motion (IVIM)-related histogram analysis parameters. This prospective study included 52...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
24 Citations
4,359 Views
14 Pages

Diffusion–Based Virtual MR Elastography of the Liver: Can It Be Extended beyond Liver Fibrosis?

  • Takashi Ota,
  • Masatoshi Hori,
  • Denis Le Bihan,
  • Hideyuki Fukui and ,
  • Hiromitsu Onishi,
  • Atsushi Nakamoto,
  • Takahiro Tsuboyama,
  • Mitsuaki Tatsumi,
  • Kazuya Ogawa and
  • Noriyuki Tomiyama
  • + 5 authors+ 0 author

30 September 2021

Background: Strong correlation has been reported between tissue water diffusivity and tissue elasticity in the liver. The purpose of this study is to explore the capability of diffusion–based virtual MR elastography (VMRE) in the characterization of...

(This article belongs to the Special Issue Diffusion-Weighted Magnetic Resonance Imaging (DWI): Clinical Potential and Applications)
  • Article
  • Open Access
8 Citations
3,571 Views
12 Pages

Exploring the Outcome of Disappearance or Small Remnants of Colorectal Liver Metastases during First-Line Chemotherapy on Hepatobiliary Contrast-Enhanced and Diffusion-Weighted MR Imaging

  • Piero Boraschi,
  • Roberto Moretto,
  • Francescamaria Donati,
  • Beatrice Borelli and ,
  • Giuseppe Mercogliano,
  • Luigi Giugliano,
  • Alessandra Boccaccino,
  • Maria Clotilde Della Pina,
  • Piero Colombatto and
  • Lucio Urbani
  • + 8 authors+ 3 authors

8 April 2023

We aimed to evaluate the outcome of the disappearance or small remnants of colorectal liver metastases during first-line chemotherapy assessed by hepatobiliary contrast-enhanced and diffusion-weighted MR imaging (DW-MRI). Consecutive patients with at...

(This article belongs to the Special Issue Metastatic Colorectal Cancer 2.0)
  • Article
  • Open Access
3 Citations
3,466 Views
13 Pages

The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences

  • Ilze Apine,
  • Monta Baduna,
  • Reinis Pitura,
  • Juris Pokrotnieks and
  • Gaida Krumina

21 July 2019

Background and objectives: The aim of the study was to assess whether there were differences between apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) and diffusion-weighted imaging with background body signal suppressio...

  • Article
  • Open Access
2 Citations
1,867 Views
13 Pages

Correlations Between MR Apparent Diffusion Coefficients and PET Standard Uptake Values in Simultaneous MR-PET Imaging of Prostate Cancer

  • Andrii Pozaruk,
  • Vitaliy Atamaniuk,
  • Kamlesh Pawar,
  • Alexandra Carey and ,
  • Jeremy Cheng,
  • Marian Cholewa,
  • Jeremy Grummet,
  • Zhaolin Chen and
  • Gary Egan
  • + 4 authors+ 0 author

This study evaluated the hypothesis that 68Ga-PSMA-11 PET SUV, obtained via an advanced DL approach, correlates better with MR ADC maps than values from conventional PET-MR. Additionally, we aimed to identify the optimal SUV threshold for maximum cor...

(This article belongs to the Section Molecular Oncology)
  • Article
  • Open Access
5 Citations
1,911 Views
14 Pages

Accurate segmentation of cardiac MR images using deep neural networks is crucial for cardiac disease diagnosis and treatment planning, as it provides quantitative insights into heart anatomy and function. However, achieving high segmentation accuracy...

(This article belongs to the Special Issue Diagnostic Biomedical Image and Processing with Artificial Intelligence and Deep Learning)
  • Review
  • Open Access
32 Citations
4,509 Views
36 Pages

Predicting Survival in Glioblastoma Patients Using Diffusion MR Imaging Metrics—A Systematic Review

  • Valentina Brancato,
  • Silvia Nuzzo,
  • Liberatore Tramontano,
  • Gerolama Condorelli and ,
  • Marco Salvatore and
  • Carlo Cavaliere
  • + 1 author+ 0 author

4 October 2020

Despite advances in surgical and medical treatment of glioblastoma (GBM), the medium survival is about 15 months and varies significantly, with occasional longer survivors and individuals whose tumours show a significant response to therapy with resp...

(This article belongs to the Special Issue Brain Tumors)
  • Article
  • Open Access
4 Citations
3,131 Views
14 Pages

Glioma Type Prediction with Dynamic Contrast-Enhanced MR Imaging and Diffusion Kurtosis Imaging—A Standardized Multicenter Study

  • Leonie Zerweck,
  • Till-Karsten Hauser,
  • Uwe Klose,
  • Tong Han and ,
  • Thomas Nägele,
  • Mi Shen,
  • Georg Gohla,
  • Arne Estler,
  • Chuanmiao Xie and
  • Vivien Richter
  • + 10 authors+ 5 authors

25 July 2024

The aim was to explore the performance of dynamic contrast-enhanced (DCE) MRI and diffusion kurtosis imaging (DKI) in differentiating the molecular subtypes of adult-type gliomas. A multicenter MRI study with standardized imaging protocols, including...

(This article belongs to the Section Cancer Biomarkers)
  • Article
  • Open Access
30 Citations
6,029 Views
14 Pages

Combination of Radiomics and Machine Learning with Diffusion-Weighted MR Imaging for Clinical Outcome Prognostication in Cervical Cancer

  • Ankush Jajodia,
  • Ayushi Gupta,
  • Helmut Prosch,
  • Marius Mayerhoefer and ,
  • Swarupa Mitra,
  • Sunil Pasricha,
  • Anurag Mehta,
  • Sunil Puri and
  • Arvind Chaturvedi
  • + 4 authors+ 0 author

5 August 2021

Objectives: To explore the potential of Radiomics alone and in combination with a diffusion-weighted derived quantitative parameter, namely the apparent diffusion co-efficient (ADC), using supervised classification algorithms in the prediction of out...

  • Article
  • Open Access
33 Citations
8,898 Views
16 Pages

The Role of Diffusion Tensor MR Imaging (DTI) of the Brain in Diagnosing Autism Spectrum Disorder: Promising Results

  • Yaser ElNakieb,
  • Mohamed T. Ali,
  • Ahmed Elnakib,
  • Ahmed Shalaby and ,
  • Ahmed Soliman,
  • Ali Mahmoud,
  • Mohammed Ghazal,
  • Gregory Neal Barnes and
  • Ayman El-Baz
  • + 4 authors+ 0 author

7 December 2021

Autism spectrum disorder (ASD) is a combination of developmental anomalies that causes social and behavioral impairments, affecting around 2% of US children. Common symptoms include difficulties in communications, interactions, and behavioral disabil...

(This article belongs to the Special Issue Computer Aided Diagnosis Sensors)
  • Article
  • Open Access
7 Citations
1,928 Views
18 Pages

Quantitative Diffusion-Weighted MR Imaging: Is There a Prognostic Role in Noninvasively Predicting the Histopathologic Type of Uveal Melanomas?

  • Pietro Valerio Foti,
  • Corrado Inì,
  • Giuseppe Broggi,
  • Renato Farina and ,
  • Stefano Palmucci,
  • Corrado Spatola,
  • Maria Chiara Lo Greco,
  • Emanuele David,
  • Rosario Caltabiano and
  • Antonio Basile
  • + 9 authors+ 4 authors

29 November 2023

Histopathologically, uveal melanomas (UMs) can be classified as spindle cell, mixed cell and epithelioid cell type, with the latter having a more severe prognosis. The aim of our study was to assess the correlation between the apparent diffusion coef...

(This article belongs to the Section Molecular Cancer Biology)
  • Article
  • Open Access
953 Views
10 Pages

Adaptive Complex Signal Average Diffusion-Weighted MR Imaging of the Liver: Utility in Breath-Hold Imaging: A Retrospective Single-Center Study

  • Masahiro Tanabe,
  • Haruki Furutani,
  • Miwa Matsukuma,
  • Mayumi Higashi and ,
  • Yuto Takemura,
  • Jo Ishii,
  • Masatoshi Yamane and
  • Katsuyoshi Ito
  • + 3 authors+ 0 author

Objectives: This study evaluated the utility of adaptive complex signal average (ACSA) diffusion-weighted imaging (DWI) specifically in breath-hold (BH) liver imaging, with a focus on signal intensity (SI) improvement, intrahepatic signal homogeneity...

(This article belongs to the Section Abdominal Imaging)
  • Article
  • Open Access
32 Citations
4,547 Views
16 Pages

Multiparametric Assessment of Changes in Renal Tissue after Kidney Transplantation with Quantitative MR Relaxometry and Diffusion-Tensor Imaging at 3 T

  • Lisa C. Adams,
  • Keno K. Bressem,
  • Sonja Scheibl,
  • Max Nunninger and ,
  • Andre Gentsch,
  • Ute L. Fahlenkamp,
  • Kai-Uwe Eckardt,
  • Bernd Hamm and
  • Marcus R. Makowski
  • + 4 authors+ 0 author

Background: Magnetic resonance relaxometry (MRR) offers highly reproducible pixel-wise parametric maps of T1 and T2 relaxation times, reflecting specific tissue properties, while diffusion-tensor imaging (DTI) is a promising technique for the charact...

(This article belongs to the Special Issue Clinical Complications after Kidney Transplantation)
  • Article
  • Open Access
5 Citations
2,393 Views
17 Pages

Preoperative Adult-Type Diffuse Glioma Subtype Prediction with Dynamic Contrast-Enhanced MR Imaging and Diffusion Weighted Imaging in Tumor Cores and Peritumoral Tissue—A Standardized Multicenter Study

  • Leonie Zerweck,
  • Uwe Klose,
  • Urs Würtemberger,
  • Vivien Richter and ,
  • Thomas Nägele,
  • Georg Gohla,
  • Kathrin Grundmann-Hauser,
  • Arne Estler,
  • Christer Ruff and
  • Till-Karsten Hauser
  • + 7 authors+ 2 authors

21 February 2025

Background/Objectives: The non-invasive identification of glioma subtypes is useful for initial diagnosis, treatment planning, and follow-up. The aim of this study was to evaluate the performance of diffusion kurtosis imaging (DKI) and dynamic contra...

(This article belongs to the Special Issue Advanced Brain Tumor Imaging)
  • Article
  • Open Access
23 Citations
4,100 Views
16 Pages

Early Response Prediction of Multiparametric Functional MRI and 18F-FDG-PET in Patients with Head and Neck Squamous Cell Carcinoma Treated with (Chemo)Radiation

  • Roland M. Martens,
  • Thomas Koopman,
  • Cristina Lavini,
  • Tim van de Brug and ,
  • Gerben J. C. Zwezerijnen,
  • J. Tim Marcus,
  • Marije R. Vergeer,
  • C. René Leemans,
  • Remco de Bree and
  • Jonas A. Castelijns
  • + 7 authors+ 2 authors

3 January 2022

Background: Patients with locally-advanced head and neck squamous cell carcinoma (HNSCC) have variable responses to (chemo)radiotherapy. A reliable prediction of outcomes allows for enhancing treatment efficacy and follow-up monitoring. Methods: Fift...

(This article belongs to the Special Issue Multimodality and Sequential Therapy in Locally Advanced Head and Neck Cancer)
  • Review
  • Open Access
100 Citations
18,967 Views
40 Pages

Current Imaging Diagnosis of Hepatocellular Carcinoma

  • Evangelos Chartampilas,
  • Vasileios Rafailidis,
  • Vivian Georgopoulou,
  • Georgios Kalarakis and ,
  • Adam Hatzidakis and
  • Panos Prassopoulos
  • + 1 author+ 0 author

18 August 2022

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer related death worldwide. Radiology has traditionally played a central role in HCC management, ranging from screening of high-risk patients to non-invasive diagnosis, as well as the...

(This article belongs to the Special Issue Diagnosis and Treatment for Hepatocellular Tumors)
  • Article
  • Open Access
3 Citations
1,446 Views
10 Pages

Microstructure Modeling of High b-Value Diffusion-Weighted Images in Glioblastoma

  • Yuan Li,
  • Michelle Kim,
  • Theodore S. Lawrence,
  • Hemant Parmar and
  • Yue Cao

Apparent diffusion coefficient has limits to differentiate solid tumor from normal tissue or edema in glioblastoma (GBM). This study investigated a microstructure model (MSM) in GBM using a clinically available diffusion imaging technique. The MSM wa...

  • Review
  • Open Access
19 Citations
4,409 Views
27 Pages

Beyond Imaging and Genetic Signature in Glioblastoma: Radiogenomic Holistic Approach in Neuro-Oncology

  • Lidia Gatto,
  • Enrico Franceschi,
  • Alicia Tosoni,
  • Vincenzo Di Nunno and ,
  • Caterina Tonon,
  • Raffaele Lodi,
  • Raffaele Agati,
  • Stefania Bartolini and
  • Alba Ariela Brandes
  • + 4 authors+ 0 author

Glioblastoma (GBM) is a malignant brain tumor exhibiting rapid and infiltrative growth, with less than 10% of patients surviving over 5 years, despite aggressive and multimodal treatments. The poor prognosis and the lack of effective pharmacological...

(This article belongs to the Section Drug Discovery, Development and Delivery)
  • Article
  • Open Access
1 Citations
1,078 Views
11 Pages

9 October 2025

Background: Microwave ablation (MWA) is an effective, minimally invasive therapy for benign thyroid nodules; however, the treatment response varies considerably. Identifying imaging biomarkers that can predict volumetric outcomes may optimize patient...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
31 Citations
16,439 Views
19 Pages

Magnetic Resonance Imaging of the Gastrointestinal Tract: Current Role, Recent Advancements and Future Prospectives

  • Francesca Maccioni,
  • Ludovica Busato,
  • Alessandra Valenti,
  • Sara Cardaccio and ,
  • Alessandro Longhi and
  • Carlo Catalano
  • + 1 author+ 0 author

This review focuses on the role of magnetic resonance imaging (MRI) in the evaluation of the gastrointestinal tract (GI MRI), analyzing the major technical advances achieved in this field, such as diffusion-weighted imaging, molecular imaging, motili...

(This article belongs to the Special Issue Advanced MRI in Clinical Diagnosis)
  • Article
  • Open Access
8 Citations
6,516 Views
15 Pages

Objective: The assessment of the usefulness of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) when qualifying patients with uterine fibroids (UFs) for magnetic resonance-guided high-intensity ultrasound (MR-HIFU). Material and methods...

(This article belongs to the Special Issue Gynecological Tumor Imaging)
  • Article
  • Open Access
24 Citations
4,931 Views
11 Pages

Granulomatous Prostatitis, the Great Mimicker of Prostate Cancer: Can Multiparametric MRI Features Help in This Challenging Differential Diagnosis?

  • Elena Bertelli,
  • Giulia Zantonelli,
  • Alberto Cinelli,
  • Sandro Pastacaldi and ,
  • Simone Agostini,
  • Emanuele Neri and
  • Vittorio Miele
  • + 2 authors+ 0 author

23 September 2022

Clinico-radiological presentation of granulomatous prostatitis (GP) is quite similar to cancer, and differential diagnosis can be very challenging. The study aims to highlight GP features based on clinical findings and multiparametric magnetic resona...

(This article belongs to the Special Issue Advanced Techniques in Body Magnetic Resonance Imaging 2.0)
  • Review
  • Open Access
27 Citations
8,098 Views
13 Pages

Magnetic resonance imaging (MRI) has the potential to serve as a biomarker for Parkinson’s disease (PD). However, the type or types of biomarker it could provide remain to be determined. At this time there is not sufficient sensitivity or specificity...

(This article belongs to the Special Issue Pathophysiology and Genetics of Movement Disorders)
  • Article
  • Open Access
1 Citations
8,384 Views
10 Pages

Assessment of the Central Nervous System in Children with Fetal Alcohol Spectrum Disorder (FASD) Using Magnetic Resonance (MR) Techniques

  • Andrzej Urbanik,
  • Monika Nardzewska-Szczepanik,
  • Teresa Jadczak-Szumiło and
  • Monika Ostrogórska

19 June 2023

The study aimed to assess central nervous systems in children diagnosed with Fetal Alcohol Spectrum Disorder (FASD), using the techniques of magnetic resonance (MRI). The analyses considered 200 children, both female and male, aged 6–17 years,...

  • Review
  • Open Access
6 Citations
5,248 Views
17 Pages

Brachial Plexopathies: A Comprehensive Radiologic Method Integrating Ultrasound and MRI

  • Giulia Pacella,
  • Raffaele Natella,
  • Federico Bruno,
  • Michela Bruno and ,
  • Donatella Franco,
  • Daniele Giuseppe Romano and
  • Marcello Zappia
  • + 2 authors+ 0 author

6 September 2025

Background: Brachial plexopathies comprise a diverse array of illnesses with multifactorial etiologies, including trauma, inflammation, neoplasia, and iatrogenic damage, frequently manifesting with nonspecific clinical symptoms. Precise and prompt im...

(This article belongs to the Section Clinical Neurology)
  • Case Report
  • Open Access
11 Citations
3,010 Views
8 Pages

Diffusion as a Natural Contrast in MR Imaging of Peripheral Artery Disease (PAD) Tissue Changes. A Case Study of the Clinical Application of DTI for a Patient with Chronic Calf Muscles Ischemia

  • Weronika Mazur,
  • Małgorzata Urbańczyk-Zawadzka,
  • Robert Banyś,
  • Rafał Obuchowicz and ,
  • Mariusz Trystuła and
  • Artur T. Krzyżak
  • + 1 author+ 0 author

This paper reports a first application of diffusion tensor imaging with corrections by using the B-matrix spatial distribution method (BSD-DTI) for peripheral artery disease (PAD) detected in the changes of diffusion tensor parameters (DTPs). A 76-ye...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Feature Paper
  • Review
  • Open Access
58 Citations
14,408 Views
26 Pages

21 April 2020

Major depressive disorder (MDD) is a severe illness imposing an increasing social and economic burden worldwide. Numerous rodent models have been developed to investigate the pathophysiology of MDD. One of the best characterized and most widely used...

(This article belongs to the Special Issue Chronic Stress Models for Mood Disorders)
  • Article
  • Open Access
1 Citations
3,808 Views
21 Pages

Background: We compared the efficiency of two MRI diffusion weighted imaging (DWI) techniques: DWI with SPIR (DWISPIR) and DWI with STIR (DWISTIR), to estimate their eligibility for quantitative assessment of Crohn’s disease activity in childre...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
51 Citations
8,076 Views
21 Pages

Advances in artificial intelligence (AI), especially deep learning (DL), have facilitated magnetic resonance imaging (MRI) data analysis, enabling AI-assisted medical image diagnoses and prognoses. However, most of the DL models are considered as &ld...

(This article belongs to the Special Issue Artificial Intelligence for Magnetic Resonance Imaging)
  • Review
  • Open Access
49 Citations
17,320 Views
16 Pages

Imaging Evaluation of Intervertebral Disc Degeneration and Painful Discs—Advances and Challenges in Quantitative MRI

  • Shota Tamagawa,
  • Daisuke Sakai,
  • Hidetoshi Nojiri,
  • Masato Sato and ,
  • Muneaki Ishijima and
  • Masahiko Watanabe
  • + 1 author+ 0 author

In recent years, various quantitative and functional magnetic resonance imaging (MRI) sequences have been developed and used in clinical practice for the diagnosis of patients with low back pain (LBP). Until now, T2-weighted imaging (T2WI), a visual...

(This article belongs to the Special Issue Paradigm Shift of Spinal Diagnosis and Treatment)
  • Article
  • Open Access
131 Views
12 Pages

Associations Between Apparent Diffusion Coefficient Values of Breast Tumors Presenting as Non-Mass Enhancement and Ki-67 Index

  • Iva Perić,
  • Boris Brkljačić,
  • Tade Tadić,
  • Kristian Jerković and ,
  • Krešimir Dolić,
  • Martina Luetić,
  • Monika Bilandžić,
  • Matija Borić and
  • Marija Ćavar
  • + 4 authors+ 0 author

5 November 2026

Objectives: This study aimed to investigate whether apparent diffusion coefficient (ADC) values of malignant breast lesions presenting as non-mass enhancement (NME) are associated with the Ki-67 proliferation index. Materials and Methods: This retros...

(This article belongs to the Section Molecular Cancer Biology)
  • Review
  • Open Access
18 Citations
5,493 Views
18 Pages

Target Definition in MR-Guided Adaptive Radiotherapy for Head and Neck Cancer

  • Mischa de Ridder,
  • Cornelis P. J. Raaijmakers,
  • Frank A. Pameijer,
  • Remco de Bree and ,
  • Floris C. J. Reinders,
  • Patricia A. H. Doornaert,
  • Chris H. J. Terhaard and
  • Marielle E. P. Philippens
  • + 3 authors+ 0 author

20 June 2022

In recent years, MRI-guided radiotherapy (MRgRT) has taken an increasingly important position in image-guided radiotherapy (IGRT). Magnetic resonance imaging (MRI) offers superior soft tissue contrast in anatomical imaging compared to computed tomogr...

(This article belongs to the Special Issue Adaptive Radiotherapy for Head and Neck Cancer)
  • Article
  • Open Access
4 Citations
3,167 Views
10 Pages

Improved Visualization of Prostate Cancer Using Multichannel Computed Diffusion Images: Combining ADC and DWI

  • Matthias Hammon,
  • Marc Saake,
  • Frederik B. Laun,
  • Rafael Heiss and ,
  • Nicola Seuss,
  • Rolf Janka,
  • Alexander Cavallaro,
  • Michael Uder and
  • Hannes Seuss
  • + 4 authors+ 0 author

(1) Background: For the peripheral zone of the prostate, diffusion weighted imaging (DWI) is the most important MRI technique; however, a high b-value image (hbDWI) must always be evaluated in conjunction with an apparent diffusion coefficient (ADC)...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
6 Citations
3,374 Views
13 Pages

Multishell Diffusion MR Tractography Yields Morphological and Microstructural Information of the Anterior Optic Pathway: A Proof-of-Concept Study in Patients with Leber’s Hereditary Optic Neuropathy

  • David Neil Manners,
  • Laura Ludovica Gramegna,
  • Chiara La Morgia,
  • Giovanni Sighinolfi and ,
  • Cristiana Fiscone,
  • Michele Carbonelli,
  • Martina Romagnoli,
  • Valerio Carelli,
  • Caterina Tonon and
  • Raffaele Lodi
  • + 5 authors+ 0 author

Tractography based on multishell diffusion-weighted magnetic resonance imaging (DWI) can be used to estimate the course of myelinated white matter tracts and nerves, yielding valuable information regarding normal anatomy and variability. DWI is sensi...

(This article belongs to the Special Issue Advances in Human Anatomy: Research Development and Innovative Medical Training)
  • Article
  • Open Access
15 Citations
4,171 Views
16 Pages

Correlation between DWI-ASPECTS Score, Ischemic Stroke Volume on DWI, Clinical Severity and Short-Term Prognosis: A Single-Center Study

  • Oana Andreea Dogariu,
  • Veronica Gheorman,
  • Ioan Dogariu,
  • Mihaela Corina Berceanu and ,
  • Carmen Valeria Albu and
  • Ioana Andreea Gheonea
  • + 1 author+ 0 author

Ischemic stroke is a significant public health concern, with its incidence expected to double over the next 40 years, particularly among individuals over 75 years old. Previous studies, such as the DAWN trial, have highlighted the importance of corre...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Review
  • Open Access
8 Citations
4,495 Views
16 Pages

26 October 2024

Mild traumatic brain injury (mTBI) is a common occurrence around the world, associated with a variety of blunt force and torsion injuries affecting all age groups. Most never reach medical attention, and the identification of acute injury and later c...

(This article belongs to the Special Issue Traumatic Brain Injury/Chronic Traumatic Encephalopathy as Cause of Alzheimer’s Disease: Physics and Molecular Biology in the Genesis of Neurodegeneration?)
  • Article
  • Open Access
24 Citations
5,793 Views
11 Pages

Detection of Glioblastoma Subclinical Recurrence Using Serial Diffusion Tensor Imaging

  • Yan Jin,
  • James W. Randall,
  • Hesham Elhalawani,
  • Karine A. Al Feghali and ,
  • Andrew M. Elliott,
  • Brian M. Anderson,
  • Lara Lacerda,
  • Benjamin L. Tran,
  • Abdallah S. Mohamed and
  • Caroline Chung
  • + 7 authors+ 2 authors

29 February 2020

Glioblastoma is an aggressive brain tumor with a propensity for intracranial recurrence. We hypothesized that tumors can be visualized with diffusion tensor imaging (DTI) before they are detected on anatomical magnetic resonance (MR) images. We retro...

(This article belongs to the Special Issue Role of Medical Imaging in Cancers)
  • Case Report
  • Open Access
2 Citations
4,556 Views
8 Pages

Magnetic-Resonance Diffusion-Tensor Tractography in the Diagnosis of Tumefactive Spinal-Cord Lesions in Neuromyelitis Optica

  • Yung Hsu,
  • Ming-Chung Chou,
  • Poh-Shiow Yeh,
  • Te-Chang Wu and ,
  • Ching-Chung Ko and
  • Tai-Yuan Chen
  • + 1 author+ 0 author

Magnetic-resonance (MR) imaging is the modality of choice for the evaluation of spinal-cord lesions. However, challenges persist in discriminating demyelinating processes from neoplastic lesions using conventional MR sequences. Consequently, an invas...

(This article belongs to the Special Issue Brain Imaging/Neuroimaging)
  • Feature Paper
  • Review
  • Open Access
19 Citations
9,125 Views
20 Pages

MRI Staging in Locally Advanced Vulvar Cancer: From Anatomy to Clinico-Radiological Findings. A Multidisciplinary VulCan Team Point of View

  • Benedetta Gui,
  • Salvatore Persiani,
  • Maura Miccò,
  • Vincenza Pignatelli and ,
  • Elena Rodolfino,
  • Giacomo Avesani,
  • Valerio Di Paola,
  • Camilla Panico,
  • Luca Russo and
  • Riccardo Manfredi
  • + 9 authors+ 4 authors

18 November 2021

MR imaging provides excellent spatial and contrast resolution to stage locally advanced vulvar cancer (LAVC) for tumor and nodal evaluation in order to facilitate the planning of treatment. Although there are no standard indications for how to estima...

(This article belongs to the Special Issue Diagnostics and Interventional Procedures in Gynecological Tumors)
  • Review
  • Open Access
2 Citations
2,083 Views
21 Pages

The Role of Advanced MR Imaging in Gliomas

  • Anastasia K. Zikou,
  • Eleni Romeo,
  • George A. Alexiou,
  • Marios Lampros and ,
  • Spyridon Voulgaris,
  • Loukas Astrakas and
  • Maria I. Argyropoulou
  • + 2 authors+ 0 author

20 January 2026

Gliomas are a significant health problem with a lot of imaging challenges. The role of imaging is no longer limited to only providing anatomic details, but with the advancement of Magnetic Resonance Imaging (MRI) techniques, it now permits the assess...

(This article belongs to the Special Issue MR-Based Neuroimaging, 2nd Edition)
  • Article
  • Open Access
1 Citations
2,095 Views
14 Pages

The Diagnostic and Prognostic Value of 18F-FDG PET/MR in Hypopharyngeal Cancer

  • Cui Fan,
  • Xinyun Huang,
  • Hao Wang,
  • Haixia Hu and ,
  • Jichang Wu,
  • Xiangwan Miao,
  • Yuenan Liu,
  • Mingliang Xiang,
  • Nijun Chen and
  • Bin Ye
  • + 5 authors+ 0 author

22 August 2025

Objective: To evaluate the diagnostic performance of fluorine 18 fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MR) in the preoperative staging of hypopharyngeal cancer (HPC), compare it with conventional enha...

(This article belongs to the Special Issue Multimodal Imaging: Enhancing Precision Medicine Across Diverse Clinical Pathways)
  • Article
  • Open Access
10 Citations
5,194 Views
17 Pages

Utility of Diffusion and Magnetization Transfer MRI in Cervical Spondylotic Myelopathy: A Pilot Study

  • Hea-Eun Yang,
  • Wan-Tae Kim,
  • Dae-Hyun Kim,
  • Seok-Woo Kim and
  • Woo-Kyoung Yoo

Diffusion tensor imaging (DTI) and magnetization transfer (MT) magnetic resonance imaging (MRI) can help detect spinal cord pathology, and tract-specific analysis of their parameters, such as fractional anisotropy (FA), mean diffusivity, axial diffus...

(This article belongs to the Special Issue Advancements in Neuroimaging)
  • Article
  • Open Access
12 Citations
3,199 Views
10 Pages

The Frequency and Causes of Not-Detected Breast Malignancy in Dynamic Contrast-Enhanced MRI

  • Donghun Song,
  • Bong Joo Kang,
  • Sung Hun Kim,
  • Jeongmin Lee and
  • Ga Eun Park

24 October 2022

Breast MR is the most sensitive imaging modality, but there are cases of malignant tumors that are not detected in MR. This study evaluated the frequency and main causes of malignant breast lesions not detected in dynamic contrast-enhanced (DCE) MR....

(This article belongs to the Special Issue Breast Cancer Imaging: Successes and Challenges)

of 6