Chronic Stress Models for Mood Disorders

Dear Colleagues,

Major depressive disorder is a major public health concern, as it is a common and often recurring condition associated with considerable functional impairments, diminished quality of life, increased medical morbidity, and mortality. Currently, the WHO predicts that by 2030, major depressive disorder will be the largest contributor to the global disease burden. Despite extensive research efforts, the exact pathophysiology of the disorder is still unknown. Effective antidepressants are available, but many of them act too slowly, and patient compliance is hindered by the numerous side effects. Animal models for depression may help us to understand the underlying pathophysiology and to develop novel, faster acting drugs with less side effects. As stress is a major contributor to the development of depressive disorders, animal models based on chronic stress exposure are the most widely used models in research to mimic the depressed behavioural phenotype.
This Special Issue will provide an open-access opportunity for publishing research studies or review articles related to animal models based on chronic stress to mirror depressive disorders. All kinds of studies, including behavioural, cellular, molecular, electrophysiological, or pharmacological studies, are welcome from researchers who work on these topics.

Prof. Boldizsár Czéh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.