Next Article in Journal
Shear Wave Elastography to Guide Perineural Hydrodissection: Two Case Reports
Previous Article in Journal
Cystic Interstitial Lung Diseases: A Pictorial Review and a Practical Guide for the Radiologist
Open AccessArticle

Comparison between Diffusion-Weighted Sequences with Selective and Non-Selective Fat Suppression in the Evaluation of Crohn’s Disease Activity: Are They Equally Useful?

1
Children Clinical University Hospital of Riga, LV 1004 Riga, Latvia
2
Department of Radiology, Riga Stradin’s University, LV 1004 Riga, Latvia
3
Department of Pathology, Riga Stradin’s University, LV 1007 Riga, Latvia
4
Department of Internal Diseases, Riga Stradin’s University, LV 1007 Riga, Latvia
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(6), 347; https://doi.org/10.3390/diagnostics10060347
Received: 28 April 2020 / Revised: 20 May 2020 / Accepted: 25 May 2020 / Published: 27 May 2020
(This article belongs to the Section Medical Imaging)
Background: We compared the efficiency of two MRI diffusion weighted imaging (DWI) techniques: DWI with SPIR (DWISPIR) and DWI with STIR (DWISTIR), to estimate their eligibility for quantitative assessment of Crohn’s disease activity in children and adults. Methods: In inflamed terminal ileum segments (n = 32 in adults, n = 46 in children), Magnetic Resonance Index of Activity (MaRIA) was calculated, ADC values of both DWI techniques were measured, and the corresponding Clermont scores calculated. ADC values of both DWI techniques were compared between both and within each patient group, assessing their mutual correlation. Correlations between MaRIA and the corresponding ADC values, and Clermont scores based on both DWI techniques were estimated. Results: No correlation between ADC of DWISPIR and DWISTIR was observed (rho = 0.27, p = 0.13 in adults, rho = 0.20, p = 0.17 in children). The correlation between MaRIA and Clermont scores was strong in both techniques—in SPIR, rho = 0.93; p < 0.0005 in adults, rho = 0.98, p < 0.0005 in children, and, in STIR, rho = 0.89; p < 0.0005 in adults, rho = 0.95, p < 0.0005 in children. The correlation between ADC and MaRIA was moderate negative for DWISTIR (rho = 0.93, p < 0.0005 in adults, rho = 0.95, p < 0.0005 in children), but, in DWISTIR, no correlation between ADC and MaRIA score was observed in adults (rho = −0.001, p = 0.99), whereas children presented low negative correlation (rho = −0.374, p = 0.01). Conclusions: DWISTIR is not suitable for quantitative assessment of Crohn’s disease activity both in children and adult patients. View Full-Text
Keywords: MR enterography; terminal ileitis; diffusion-weighted imaging; DWI; DWIBS; ADC; MaRIA; Clermont score; DWI fat suppression techniques MR enterography; terminal ileitis; diffusion-weighted imaging; DWI; DWIBS; ADC; MaRIA; Clermont score; DWI fat suppression techniques
Show Figures

Figure 1

MDPI and ACS Style

Apine, I.; Pitura, R.; Franckevica, I.; Pokrotnieks, J.; Krumina, G. Comparison between Diffusion-Weighted Sequences with Selective and Non-Selective Fat Suppression in the Evaluation of Crohn’s Disease Activity: Are They Equally Useful? Diagnostics 2020, 10, 347.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop