Directly applying brain signals to operate a mobile manned platform, such as a vehicle, may help people with neuromuscular disorders regain their driving ability. In this paper, we developed a novel electroencephalogram (EEG) signal-based driver&ndas...
In this work, we developed a novel system to detect the braking intention of drivers in emergency situations using electroencephalogram (EEG) signals. The system acquired eight-channel EEG and motion-sensing data from a custom-designed EEG headset du...
Electric vehicle (EV) charging facilities are essential to their development and deployment. These days, autonomous microgrids that use renewable energy resources to energize charging stations for electric vehicles alleviate pressure on the public el...
In this paper, we present a vehicle active safety model for vehicle speed control based on driver vigilance detection using low-cost, comfortable, wearable electroencephalographic (EEG) sensors and sparse representation. The proposed system consists...
Autonomous navigation in unknown; map-free environments is a core requirement for advanced robotics. While significant breakthroughs have been achieved in terrestrial scenarios, extending this capability to the unstructured, dynamic, and harsh underw...
Modern achievements accomplished in both cognitive neuroscience and human–machine interaction technologies have enhanced the ability to control devices with the human brain by using Brain–Computer Interface systems. Particularly, the deve...
The article presents an overview of several studies in the field of Brain–Computer Interfaces (BCIs), the requirements for the architecture of such promising devices, as well as multi-modal BCI for drone control in a smart-city environment. Dis...
An electromiographic (EMG)-based human-machine interface (HMI) is a communication pathway between a human and a machine that operates by means of the acquisition and processing of EMG signals. This article explores the use of EMG-based HMIs in the st...
This study presents a human-computer interaction combined with a brain-machine interface (BMI) and obstacle detection system for remote control of a wheeled robot through movement imagery, providing a potential solution for individuals facing challen...
Traumatic brain injury (TBI) could result in edema and cause an increase in intracranial pressure of the brain resulting in mortality and morbidity. Although there is hyperosmolarity therapy available for this pathophysiological event, it remains con...
With the development of in-wheel technology (IWT), the design of the electric vehicles (EV) is getting much improved. The anti-lock braking system (ABS), which is a safety benchmark for automotive braking, is particularly important. Installing the br...
The ATP-binding cassette transporter member A1 (ABCA1) and apolipoprotein E (ApoE) are major cholesterol transporters that play important roles in cholesterol homeostasis in the brain. Previous research demonstrated that specific deletion of brain-AB...
Kynurenic acid (KYNA), an endogenous neuroprotectant with antiexcitotoxic, antioxidant, and anti-inflammatory effects, is synthesized through the tryptophan-kynurenine (KYN) pathway. We investigated whether brain KYN or KYNA levels were affected by a...
It has been shown that propofol can induce widespread apoptosis in neonatal mouse brains followed by long-term cognitive dysfunction. However, selective brain area and cell vulnerability to propofol remains unknown. This study was aimed to dissect to...
Background/Objectives: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive dementia and brain accumulation of Aβ-peptide-containing plaques, gliosis, neuroimmune changes, and neurofibrillary tangles. Mushro...
Brain-like intelligent decision-making is a prevailing trend in today’s world. However, inspired by bionics and computer science, the linear neural network has become one of the main means to realize human-like decision-making and control. This...
The opening of the mitochondrial permeability transition pore (mPTP) has emerged as a pivotal event following traumatic brain injury (TBI). Evidence showing the impact of the translocator protein (TSPO) over mPTP activity has prompted several studies...
Background: Hypoxic–ischemic encephalopathy (HIE) around the time of birth results from loss of oxygen (hypoxia) and blood supply (ischemia). Exogenous infusion of multi-potential cells, including human amnion epithelial cells (hAECs), can redu...
On-road vehicle emissions play a crucial role in affecting air quality and human exposure, particularly in megacities. In the absence of comprehensive traffic monitoring networks with the general lack of intelligent transportation systems (ITSs) and...
Controller design and signal processing for the control of air-vehicles have gained extreme importance while interacting with humans to form a brain–computer interface. This is because fewer commands need to be mapped into multiple controls. Fo...
The immune system, particularly T lymphocytes and cytokines, has been implicated in the progression of brain injury after intracerebral hemorrhage (ICH). Although studies have shown that transplanted neural stem cells (NSCs) protect the central nervo...
Aging is a naturally occurring process inevitably affecting each living human. The brain is adversely affected by aging with increased risks of developing various neurological disorders. Thus, it is essential to investigate practical approaches that...
Matrix metalloproteinases (MMPs) are endopeptidases responsible for the cleavage of intra- and extracellular proteins. Several brain MMPs have been implicated in neurological disorders including epilepsy. We recently showed that the novel gelatinase...
D-galactose (D-gal) administration causes oxidative disorder and is widely utilized in aging animal models. Therefore, we subcutaneously injected D-gal at 200 mg/kg BW dose to assess the potential preventive effect of thymoquinone (TQ) and curcumin (...
Aberrant metabolism is a hallmark of malignancies including gliomas. Intracranial microdialysis enables the longitudinal collection of extracellular metabolites within CNS tissues including gliomas and can be leveraged to evaluate changes in the CNS...
ATP-binding cassette transporter A1 (ABCA1) plays an important role in the regulation of apolipoprotein E (ApoE) and the biogenesis of high-density lipoprotein (HDL) cholesterol in the mammalian brain. Cholesterol is a major source for myelination. H...
It is increasingly recognized that early perturbation of energy metabolism might have important implications in management and ultimately the neurological outcome in patients with traumatic brain injury (TBI). At the same time, treatments and screeni...
For the treatment of neurological diseases, achieving sufficient exposure to the brain parenchyma is a critical determinant of drug efficacy. The blood–brain barrier (BBB) functions to tightly control the passage of substances between the blood...
Behavioral disorders affect millions of people worldwide. Hypertension contributes to both the development and progression of brain damage and cognitive dysfunction and could represent the most powerful modifiable risk factor for cerebral vessel dysf...
To address the safety and efficient driving issues of human–machine shared control vehicles (HSCVs) in future complex traffic environments, this paper proposes a game theory-based interactive control method between HSCVs and surrounding autonom...
The polyphenol resveratrol (RVT) may drive protective mechanisms of cerebral homeostasis during the hypoperfusion/reperfusion triggered by the transient bilateral common carotid artery occlusion followed by reperfusion (BCCAO/R). This immunochemical...
The integration of vehicle-to-grid (V2G), grid-to-vehicle (G2V), and vehicle-to-everything (V2X) systems into an energy ecosystem represents a transformative approach. These systems enable bidirectional energy flow between electric vehicles (EVs), po...
Background: The efficacy of melatonin in reducing vasogenic and cytotoxic edema was investigated using a model of permanent middle cerebral artery occlusion (pMCAO). Methods: Rats underwent pMCAO, followed by intravenous administration of either mela...
(1) Background: Neonatal brain injury can lead to permanent neurodevelopmental impairments. Notably, suppressing inflammatory pathways may reduce damage. To determine the role of neuroinflammation in the progression of neonatal brain injury, we inves...
Growth hormone (GH)-releasing hormone (GHRH) has been suggested to play a crucial role in brain function. We aimed to further investigate the effects of a novel GHRH antagonist of the Miami (MIA) series, MIA-602, on emotional disorders and explore th...
Brain–computer interface (BCI) offers a novel means of communication and control for individuals with disabilities and can also enhance the interactions between humans and machines for the broader population. This paper explores the brain neura...
The brain–computer interface (BCI) is a mechanism for extracting information from the brain, with this information used for various applications. This study proposes a method to control an unmanned aerial vehicle (UAV) flying through a BCI syst...
Modern autonomous vehicles with an electric/electronic (E/E) architecture represent the next big step in the automation and evolution of smart and self-driving vehicles. This technology is of significant interest nowadays and humans are currently wit...
This study aimed to examine the antidepressant properties of apigenin in an experimental mouse model of chronic mild stress (CMS). Three weeks following CMS, albino mice of either sex were tested for their antidepressant effects using the tail suspen...
Perinatal hypoxic-ischemic (HI) brain injury, often in conjunction with an inflammatory insult, is the most common cause of death or disability in neonates. Therapeutic hypothermia (TH) is the standard of care for HI encephalopathy in term and near-t...
Postnatal glucocorticoids such as dexamethasone are effective in promoting lung development in preterm infants, but are prescribed cautiously due to concerns of neurological harm. We developed an analysis pipeline for post-mortem magnetic resonance i...
Rice (Oryza sativa L.) is the richest source of γ-oryzanol, a compound endowed with antioxidant and anti-inflammatory properties. γ-Oryzanol has been demonstrated to cross the blood-brain barrier in intact form and exert beneficial effect...
Background: Clinical and experimental evidence suggests comorbidity between diabetes mellitus (DM) and epilepsy, including a higher incidence of status epilepticus (SE). However, the association between Type 2 Diabetes Mellitus (T2DM) and epilepsy is...
Hypoxic-ischaemic brain injury at birth is associated with 1–3/1000 cases of moderate to severe encephalopathy. Previously, we have shown that connexin 43 hemichannel blockade, with a specific mimetic peptide, reduced the occurrence of seizures, impr...
The application of deep learning in autonomous vehicles has surged over the years with advancements in technology. This research explores the integration of deep learning algorithms into autonomous vehicles (AVs), focusing on their role in perception...
Driver models, which provide mathematical or computational representations of human driving behavior, are crucial for intelligent driving systems by enabling stable and repeatable operations. However, existing models typically employ fixed weighting...
Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor outcomes. Manganese porph...
There is a strong trend in the development of control systems for multi-rotor unmanned aerial vehicles (UAVs), where minimization of a control signal effort is conducted to extend the flight time. The aim of this article is to shed light on the probl...
Gyrification, the folding of the cerebral cortex, plays a crucial role in brain development and function. Perinatal hypoxia–ischemia (HI) is a leading cause of neonatal brain injury, affecting cortical folding that can be measured by the gyrifi...
Organophosphoate (OP) chemicals are known to inhibit the enzyme acetylcholinesterase (AChE). Studying OP poisoning is difficult because common small animal research models have serum carboxylesterase, which contributes to animals’ resistance to...
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