- Article
Naja atra Cardiotoxin 3 Elicits Autophagy and Apoptosis in U937 Human Leukemia Cells through the Ca2+/PP2A/AMPK Axis
- Jing-Ting Chiou,
- Yi-Jun Shi,
- Liang-Jun Wang,
- Chia-Hui Huang,
- Yuan-Chin Lee and
- Long-Sen Chang
Cardiotoxins (CTXs) are suggested to exert their cytotoxicity through cell membrane damage. Other studies show that penetration of CTXs into cells elicits mitochondrial fragmentation or lysosome disruption, leading to cell death. Considering the role...