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230 Results Found

  • Article
  • Open Access
28 Citations
4,736 Views
12 Pages

Naja atra Cardiotoxin 3 Elicits Autophagy and Apoptosis in U937 Human Leukemia Cells through the Ca2+/PP2A/AMPK Axis

  • Jing-Ting Chiou,
  • Yi-Jun Shi,
  • Liang-Jun Wang,
  • Chia-Hui Huang,
  • Yuan-Chin Lee and
  • Long-Sen Chang

12 September 2019

Cardiotoxins (CTXs) are suggested to exert their cytotoxicity through cell membrane damage. Other studies show that penetration of CTXs into cells elicits mitochondrial fragmentation or lysosome disruption, leading to cell death. Considering the role...

  • Article
  • Open Access
21 Citations
5,774 Views
15 Pages

Targeted Editing of the pp38 Gene in Marek’s Disease Virus-Transformed Cell Lines Using CRISPR/Cas9 System

  • Yaoyao Zhang,
  • Jun Luo,
  • Na Tang,
  • Man Teng,
  • Vishwanatha R.A.P. Reddy,
  • Katy Moffat,
  • Zhiqiang Shen,
  • Venugopal Nair and
  • Yongxiu Yao

26 April 2019

Marek’s disease virus (MDV), a lymphotropic α-herpesvirus associated with T-cell lymphomas in chickens, is an excellent model for herpesvirus biology and virus-induced oncogenesis. Marek’s disease (MD) is also one of the cancers aga...

  • Article
  • Open Access
2 Citations
4,264 Views
14 Pages

21 February 2022

Marek’s disease virus (MDV) is a member of alphaherpesviruses associated with Marek’s disease, a highly contagious neoplastic disease in chickens. The availability of the complete sequence of the viral genome allowed for the identificatio...

  • Article
  • Open Access
19 Citations
3,273 Views
20 Pages

29 October 2022

As a typical ancient tetraploid, soybean (Glycine max) is an important oil crop species and plays a crucial role in supplying edible oil, plant protein and animal fodder worldwide. As global warming intensifies, the yield of soybean in the field is o...

  • Article
  • Open Access
6 Citations
2,389 Views
14 Pages

PROTEIN PHOSPHATASE 2C08, a Negative Regulator of Abscisic Acid Signaling, Promotes Internode Elongation in Rice

  • Jaeeun Song,
  • Eunji Ga,
  • Sangkyu Park,
  • Hyo Lee,
  • In Sun Yoon,
  • Saet Buyl Lee,
  • Jong-Yeol Lee and
  • Beom-Gi Kim

Clade A protein phosphatase 2Cs (PP2CAs) negatively regulate abscisic acid (ABA) signaling. Here, we investigated the functions of OsPP2CAs and their crosstalk with ABA and gibberellic acid (GA) signaling pathways in rice (Oryza sativa). Among the ni...

  • Article
  • Open Access
28 Citations
4,270 Views
17 Pages

OsPP2C09 Is a Bifunctional Regulator in Both ABA-Dependent and Independent Abiotic Stress Signaling Pathways

  • Myung Ki Min,
  • Rigyeong Kim,
  • Woo-Jong Hong,
  • Ki-Hong Jung,
  • Jong-Yeol Lee and
  • Beom-Gi Kim

Clade A Type 2C protein phosphatases (PP2CAs) negatively regulate abscisic acid (ABA) signaling and have diverse functions in plant development and in response to various stresses. In this study, we showed that overexpression of the rice ABA receptor...

  • Article
  • Open Access
865 Views
20 Pages

Characterization of 3D-Printed Glass Fiber-Filled and Calcium Carbonate-Filled Polypropylene Components for Surgical Planning

  • Núria Adell-Gómez,
  • Irene Buj-Corral,
  • Miquel Domingo-Espin,
  • Jordi Llumà,
  • J. Antonio Travieso-Rodríguez,
  • Josep Rubio-Palau,
  • César García-Fontecha,
  • Alejandro Domínguez-Fernández and
  • Arnau Valls-Esteve

4 October 2025

The purpose of this study is to characterize two different 3D-printed materials, glass fiber-filled polypropylene (GF-PP) and calcium carbonate-filled polypropylene (CaCO3-PP), which make it possible to obtain surgical bone models at a reasonable cos...

  • Article
  • Open Access
15 Citations
3,356 Views
15 Pages

The CCCH-Type Zinc-Finger Protein GhC3H20 Enhances Salt Stress Tolerance in Arabidopsis thaliana and Cotton through ABA Signal Transduction Pathway

  • Qi Zhang,
  • Jingjing Zhang,
  • Fei Wei,
  • Xiaokang Fu,
  • Hengling Wei,
  • Jianhua Lu,
  • Liang Ma and
  • Hantao Wang

The CCCH zinc-finger protein contains a typical C3H-type motif widely existing in plants, and it plays an important role in plant growth, development, and stress responses. In this study, a CCCH zinc-finger gene, GhC3H20, was isolated and thoroughly...

  • Article
  • Open Access
4 Citations
3,449 Views
14 Pages

A New Insight into 6-Pentyl-2H-pyran-2-one against Peronophythora litchii via TOR Pathway

  • Yinggu Wu,
  • Xinyu Li,
  • Li Dong,
  • Tong Liu,
  • Zhengbin Tang,
  • Runmao Lin,
  • Justice Norvienyeku and
  • Mengyu Xing

21 August 2023

The litchi downy blight disease of litchi caused by Peronophythora litchii accounts for severe losses in the field and during storage. While ample quantitative studies have shown that 6-pentyl-2H-pyran-2-one (6PP) possesses antifungal activities agai...

  • Article
  • Open Access
11 Citations
3,389 Views
18 Pages

14 September 2022

Marek’s disease virus (MDV) is an important oncogenic α-herpesvirus that induces Marek’s disease (MD), characterized by severe immunosuppression and rapid-onset T-cell lymphomas in its natural chicken hosts. Historically, MD is rega...

  • Article
  • Open Access
7 Citations
2,408 Views
21 Pages

29 December 2023

The use of plastics in automobiles is increasing dramatically due to their advantages of low weight and cost-effectiveness. Various products can be manufactured by recycling end-of-life vehicle (ELV) plastic waste, enhancing sustainability within thi...

  • Article
  • Open Access
28 Citations
6,723 Views
12 Pages

Application of CRISPR/Cas9 Gene Editing System on MDV-1 Genome for the Study of Gene Function

  • Yaoyao Zhang,
  • Na Tang,
  • Yashar Sadigh,
  • Susan Baigent,
  • Zhiqiang Shen,
  • Venugopal Nair and
  • Yongxiu Yao

24 May 2018

Marek’s disease virus (MDV) is a member of alphaherpesviruses associated with Marek’s disease, a highly contagious neoplastic disease in chickens. Complete sequencing of the viral genome and recombineering techniques using infectious bact...

  • Review
  • Open Access
50 Citations
13,429 Views
10 Pages

Ca2+/calmodulin (CaM)-dependent protein kinase II (CaMKII), a multifunctional serine (Ser)/threonine (Thr) protein kinase, regulates diverse activities related to Ca2+-mediated neuronal plasticity in the brain, including synaptic activity and gene ex...

  • Review
  • Open Access
31 Citations
12,678 Views
25 Pages

18 November 2014

Second messengers are intracellular substances regulated by specific external stimuli globally known as first messengers. Cells rely on second messengers to generate rapid responses to environmental changes and the importance of their roles is becomi...

  • Article
  • Open Access
8 Citations
3,113 Views
12 Pages

Calcium-Polyphosphate Submicroparticles (CaPP) Improvement Effect of the Experimental Bleaching Gels’ Chemical and Cellular-Viability Properties

  • Mariángela Ivette Guanipa Ortiz,
  • Juliana Jarussi dos Santos,
  • Jonny Burga Sánchez,
  • Ubirajara Pereira Rodrigues-Filho,
  • Flávio Henrique Baggio Aguiar,
  • Klaus Rischka and
  • Débora Alves Nunes Leite Lima

4 January 2023

The aim of this research was to develop and characterize the chemical and cellular-viability properties of an experimental high-concentration bleaching gel (35 wt%-H2O2) containing calcium-polyphosphate particles (CaPP) at two concentrations (0.5 wt%...

  • Article
  • Open Access
7 Citations
4,065 Views
21 Pages

Regulation of ABA-Non-Activated SNF1-Related Protein Kinase 2 Signaling Pathways by Phosphatidic Acid

  • Maria Klimecka,
  • Maria Bucholc,
  • Justyna Maszkowska,
  • Ewa Krzywińska,
  • Grażyna Goch,
  • Małgorzata Lichocka,
  • Jadwiga Szczegielniak and
  • Grażyna Dobrowolska

Phosphatidic acid (PA) is involved in the regulation of plant growth and development, as well as responses to various environmental stimuli. Several PA targets in plant cells were identified, including two SNF1-related protein kinases 2 (SnRK2s), SnR...

  • Article
  • Open Access
22 Citations
8,039 Views
14 Pages

Anti-Inflammatory Properties of Cannabidiol and Beta-Caryophyllene Alone or Combined in an In Vitro Inflammation Model

  • Costanza Mazzantini,
  • Zahraa El Bourji,
  • Carmen Parisio,
  • Pier Luigi Davolio,
  • Arianna Cocchi,
  • Domenico E. Pellegrini-Giampietro and
  • Elisa Landucci

Cannabis contains over 500 different compounds, including cannabinoids, terpenoids, and flavonoids. Cannabidiol (CBD) is a non-psychoactive constituent, whereas beta-caryophyllene (BCP) is one of most the well-known terpenoids of Cannabis sativa. In...

  • Article
  • Open Access
59 Citations
7,142 Views
18 Pages

17 October 2018

Using supercritical nitrogen as the physical foaming agent, microcellular polypropylene (PP) nanocomposites were prepared in microcellular injection molding. The main purpose of this work is to study effects of content of nano-CaCO3 on the crystalliz...

  • Article
  • Open Access
16 Citations
3,462 Views
21 Pages

Furin Prodomain ppFurin Enhances Ca2+ Entry Through Orai and TRPC6 Channels’ Activation in Breast Cancer Cells

  • Jose J. López,
  • Geraldine Siegfried,
  • Carlos Cantonero,
  • Fabienne Soulet,
  • Jean Descarpentrie,
  • Tarik Smani,
  • Iker Badiola,
  • Simon Pernot,
  • Serge Evrard and
  • Abdel-Majid Khatib
  • + 1 author

1 April 2021

The intracellular calcium concentration ([Ca2+]i) modulation plays a key role in the regulation of cellular growth and survival in normal cells and failure of [Ca2+]i homeostasis is involved in tumor initiation and progression. Here we showed that in...

  • Article
  • Open Access
14 Citations
3,710 Views
9 Pages

25 April 2021

Polypropylene (PP) is a commodity material that has been increasingly used in different industries in the past two decades due to its versatile properties when enhanced with additives. Homo polypropylene, in general, has weak mechanical properties an...

  • Article
  • Open Access
1,506 Views
20 Pages

Evaluation of the PP6D5 Polymer as a Novel Non-Viral Vector in the Development of a CRISPR/nCas9-Based Gene Therapy for Tay–Sachs Disease

  • Jacky M. Guerrero-Vargas,
  • Diego A. Suarez-Garcia,
  • Andrés F. Leal,
  • Ivonne L. Diaz-Ariza,
  • León D. Pérez-Pérez,
  • Angela J. Espejo-Mojica and
  • Carlos J. Alméciga-Díaz

Background/Objectives: Tay–Sachs disease (TSD) is a neurodegenerative disorder caused by a deficiency in β-hexosaminidase A (HexA), which accumulates GM2 gangliosides, primarily in neurons. Currently, therapeutic options are limited, highl...

  • Article
  • Open Access
19 Citations
3,512 Views
15 Pages

7 February 2020

A combined in-mold decoration and microcellular injection molding (IMD/MIM) method has been used in this paper. The foamed PP/nano-CaCO3 composites were prepared to investigate their mechanical properties, cellular structure, and surface quality. The...

  • Article
  • Open Access
1 Citations
1,216 Views
19 Pages

Research has shown that first (L1) and second language (L2) speakers actively make predictions about upcoming linguistic information, though L2 speakers are less efficient. While prediction mechanisms are assumed to be qualitatively the same, quantit...

  • Review
  • Open Access
6 Citations
5,861 Views
26 Pages

Imaging of Hepatitis B Virus Nucleic Acids: Current Advances and Challenges

  • Luisa F. Bustamante-Jaramillo,
  • Joshua Fingal,
  • Marie-Lise Blondot,
  • Gustaf E. Rydell and
  • Michael Kann

8 March 2022

Hepatitis B virus infections are the main reason for hepatocellular carcinoma development. Current treatment reduces the viral load but rarely leads to virus elimination. Despite its medical importance, little is known about infection dynamics on the...

  • Review
  • Open Access
15 Citations
9,065 Views
19 Pages

Natural Substances as Valuable Alternative for Improving Conventional Antifungal Chemotherapy: Lights and Shadows

  • Juan Carlos Argüelles,
  • Ruth Sánchez-Fresneda,
  • Alejandra Argüelles and
  • Francisco Solano

5 May 2024

Fungi are eukaryotic organisms with relatively few pathogenic members dangerous for humans, usually acting as opportunistic infections. In the last decades, several life-threatening fungal infections have risen mostly associated with the worldwide ex...

  • Review
  • Open Access
25 Citations
7,949 Views
24 Pages

The PPP1R15 Family of eIF2-alpha Phosphatase Targeting Subunits (GADD34 and CReP)

  • Danielle Hicks,
  • Krithika Giresh,
  • Lisa A. Wrischnik and
  • Douglas C. Weiser

10 December 2023

The vertebrate PPP1R15 family consists of the proteins GADD34 (growth arrest and DNA damage-inducible protein 34, the product of the PPP1R15A gene) and CReP (constitutive repressor of eIF2α phosphorylation, the product of the PPP1R15B gene), bo...

  • Article
  • Open Access
90 Citations
5,965 Views
14 Pages

As the core components of abscisic acid (ABA) signal pathway, Clade A PP2C (PP2C-A) phosphatases in ABA-dependent stress responses have been well studied in Arabidopsis. However, the roles and natural variations of maize PP2C-A in stress responses re...

  • Article
  • Open Access
9 Citations
2,379 Views
24 Pages

22 March 2023

The present study evaluates the effect of purple potato (PP) powder and citric acid (CA) on the regulation of the colour change of 3D (three-dimensional) printed mackerel mince (Scomber scombrus). In addition, the effects of PP and CA content on the...

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,852 Views
21 Pages

Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells

  • Syevda Tagirova Sirenko,
  • Ihor Zahanich,
  • Yue Li,
  • Yevgeniya O. Lukyanenko,
  • Alexey E. Lyashkov,
  • Bruce D. Ziman,
  • Kirill V. Tarasov,
  • Antoine Younes,
  • Daniel R. Riordon and
  • Edward G. Lakatta
  • + 4 authors

10 November 2021

Spontaneous AP (action potential) firing of sinoatrial nodal cells (SANC) is critically dependent on protein kinase A (PKA) and Ca2+/calmodulin-dependent protein kinase II (CaMKII)-dependent protein phosphorylation, which are required for the generat...

  • Article
  • Open Access
6 Citations
2,879 Views
12 Pages

Early Cellular Responses Induced by Sedimentary Calcite-Processed Particles in Bright Yellow 2 Tobacco Cultured Cells

  • Daniel Tran,
  • Tingting Zhao,
  • Delphine Arbelet-Bonnin,
  • Takashi Kadono,
  • Patrice Meimoun,
  • Sylvie Cangémi,
  • Tomonori Kawano,
  • Rafik Errakhi and
  • François Bouteau

Calcite processed particles (CaPPs, Megagreen®) elaborated from sedimentary limestone rock, and finned by tribomecanic process were found to increase photosynthetic CO2 fixation grapevines and stimulate growth of various cultured plants. Due to their...

  • Article
  • Open Access
4 Citations
2,407 Views
15 Pages

Preparation and Characterization of TCPP-CaMMT Nanocompound and Its Composite with Polypropylene

  • Junming Geng,
  • Yanhua Lan,
  • Shanshan Liu,
  • Jiyu He,
  • Rongjie Yang and
  • Dinghua Li

22 April 2022

Based on the molecular dynamics method, the tris-(1-chloropropan-2yl) phosphate (TCPP)/montmorillonite (MMT) molecular model was established to study the binding energy and microstructure changes in TCPP and MMT. The theoretical simulation results sh...

  • Article
  • Open Access
7 Citations
2,892 Views
12 Pages

15 November 2021

Heat shock protein (HSP) 70 is a molecular chaperone that regulates protein structure in response to thermal stress. In addition, HSP70 is involved in post-translational modification and is related to the severity of some diseases. Here, we tested th...

  • Article
  • Open Access
21 Citations
3,920 Views
19 Pages

10 September 2022

Calmodulin-binding transcription activator (CAMTA) is a transcription factor family containing calmodulin (CaM) binding sites and is involved in plant development. Although CAMTAs in Arabidopsis have been extensively investigated, the functions of CA...

  • Article
  • Open Access
1 Citations
1,293 Views
18 Pages

Mesenchymal Stem Cell Plasticity: What Role Do Culture Conditions and Substrates Play in Shaping Biomechanical Signatures?

  • Marina Danalache,
  • Lena Karin Gaa,
  • Charline Burgun,
  • Felix Umrath,
  • Andreas Naros and
  • Dorothea Alexander

Cell functionality, driven by remarkable plasticity, is strongly influenced by mechanical forces that regulate mesenchymal stem cell (MSC) fate. This study explores the biomechanical properties of jaw periosteal cells (JPCs) and induced mesenchymal s...

  • Article
  • Open Access
11 Citations
2,745 Views
13 Pages

23 August 2023

The pigments responsible for eggshell color and patterning in birds are protoporphyrin IX (PP) and biliverdin (BV). Both are involved in the catalytic degradation of the hemo group. Bilirubin (BR), another pigment, is produced when BV is broken down....

  • Article
  • Open Access
6 Citations
3,537 Views
25 Pages

6 October 2022

The search for strategies for strengthening the synaptic efficiency in Aβ25-35-treated slices is a challenge for the compensation of amyloidosis-related pathologies. Here, we used the recording of field excitatory postsynaptic potentials (fEPSPs...

  • Article
  • Open Access
2,311 Views
10 Pages

A Novel Prophylactic Device Against Head Deformity to Prevent Severe Positional Plagiocephaly

  • Yukari Tanaka,
  • Hiroshi Miyabayashi,
  • Takanori Noto,
  • Risa Kato,
  • Nobuhiko Nagano and
  • Ichiro Morioka

Background/Objectives: Preventing head deformity in the early postnatal period could avert positional plagiocephaly (PP). Accordingly, we developed a novel prophylactic device to prevent head deformity and examined its impact on the incidence of PP a...

  • Article
  • Open Access
13 Citations
6,509 Views
11 Pages

9 January 2024

This study investigated PAPE effects of two conditioning activities (CA) and recovery times on the peak jumping power (PP) of elite female volleyball athletes. Players performed CA separately: three sets of three repetitions of back squats with 85% o...

  • Article
  • Open Access
5 Citations
7,042 Views
19 Pages

17 June 2011

Common synthetic dyes, e.g., Weak Acid Pink Red B (APRB, C.I. 18073), Mordant Blue 9 (MB, C.I.14855) and Acid Brilliant Blue 6B (ABB6B, C.I. 42660), can be removed from water by in situ hybridization with CaCO3, BaSO4 and Ca3(PO4)2 and the resulting...

  • Article
  • Open Access
11 Citations
7,805 Views
18 Pages

Recycling Pomelo Peel Waste in the Form of Hydrochar Obtained by Microwave-Assisted Hydrothermal Carbonization

  • Yu-Jie Wang,
  • Nan Li,
  • Guo-Rong Ni,
  • Chun-Huo Zhou,
  • Xin Yin and
  • Hua-Jun Huang

18 December 2022

Pomelo peel (PP) is a kind of solid waste that is produced in the processing industry of honey pomelo. This study deeply explored the feasibility of recycling PP in the form of hydrochar (HC) by microwave-assisted hydrothermal carbonization (HTC) tec...

  • Article
  • Open Access
54 Citations
5,275 Views
11 Pages

Effect of Sodium Pyrophosphate on the Reverse Flotation of Dolomite from Apatite

  • Yanfei Chen,
  • Qiming Feng,
  • Guofan Zhang,
  • Dezhi Liu and
  • Runzhe Liu

29 June 2018

In this study, the effect of sodium pyrophosphate (NaPP) on the separation of apatite from dolomite by flotation was systematically investigated. Flotation results revealed that NaPP could selectively depress the flotation of apatite, thus realizing...

  • Article
  • Open Access
2 Citations
2,258 Views
14 Pages

Enzymatically Driven Mineralization of a Calcium–Polyphosphate Bleaching Gel

  • Mariangela Ivette Guanipa Ortiz,
  • Yendry Regina Corrales Ureña,
  • Flávio Henrique Baggio Aguiar,
  • Débora Alves Nunes Leite Lima and
  • Klaus Rischka

To examined alkaline phosphatase enzyme (ALP) activity and the effects of incorporating it in the thickener solution of a hydrogen-peroxide-based bleaching gel containing calcium-polyphosphate (CaPP) on the orthophosphate (PO43−) levels, bleach...

  • Article
  • Open Access
25 Citations
6,154 Views
15 Pages

17 November 2019

Unfilled and talc-filled Copolymer Polypropylene (PP) samples were produced through low-pressure foam-injection molding (FIM). The foaming stage of the process has been facilitated through a chemical blowing agent (C6H7NaO7 and CaCO3 mixture), a phys...

  • Article
  • Open Access
30 Citations
3,861 Views
18 Pages

Controlled atmosphere (CA) has been used to alleviate chilling injury (CI) of horticultural crops caused by cold storage. However, the effects of CA treatment on peach fruit sensory quality and flavor-related chemicals suffering from CI remain largel...

  • Article
  • Open Access
11 Citations
3,942 Views
12 Pages

Effect of Neutralizer on Transparency of Nucleating Agent-Containing Polypropylene

  • Shohei Iwasaki,
  • Yohei Uchiyama,
  • Miwa Tenma and
  • Masayuki Yamaguchi

24 February 2021

The effects of neutralizer species on the transparency of injection-molded plates were studied using isotactic polypropylene (PP) containing a crystal nucleating agent—i.e., 1,3:2,4-bis-o-(4-methylbenzylidene)-d-sorbitol (MDBS). A plate containing li...

  • Article
  • Open Access
14 Citations
8,103 Views
13 Pages

The epidermis is an important tissue in Homo sapines and other animals, and an abnormal epidermis will cause many diseases. Phosphatase 2A (PP2A) is an important serine and threonine phosphatase. The α isoform of the PP2A catalytic subunit (Ppp2ca ge...

  • Article
  • Open Access
7 Citations
2,743 Views
19 Pages

27 June 2024

The aim of this study was to prepare and characterize stable non−covalent ternary complexes based on pea protein (PP, 0.5%), hyaluronic acid (HA, 0.125%), and chlorogenic acid (CA, 0~0.03%). The ternary complexes were comprehensively evaluated...

  • Article
  • Open Access
4 Citations
3,612 Views
17 Pages

The Spasmolytic, Bronchodilator, and Vasodilator Activities of Parmotrema perlatum Are Explained by Anti-Muscarinic and Calcium Antagonistic Mechanisms

  • Musaddique Hussain,
  • Hazoor Bakhsh,
  • Shahzada Khurram Syed,
  • Malik Saad Ullah,
  • Ali M. Alqahtani,
  • Taha Alqahtani,
  • Afaf A. Aldahish,
  • Talha Bin Emran,
  • Kashif Ur Rehman and
  • Khalid Hussain Janbaz

20 October 2021

Parmotremaperlatum is traditionally used in different areas of Pakistan to treat gastrointestinal, respiratory, and vascular diseases. This study evaluates the underlying mechanisms for traditional uses of P. perlatum in diarrhea, asthma, and hyperte...

  • Article
  • Open Access
9 Citations
4,023 Views
17 Pages

Reduced Cholinergic Activity in the Hippocampus of Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein Knockout Mice

  • Yuta Madokoro,
  • Yuta Yoshino,
  • Daisuke Kato,
  • Toyohiro Sato,
  • Masayuki Mizuno,
  • Tetsuko Kanamori,
  • Masamitsu Shimazawa,
  • Hideki Hida,
  • Hideaki Hara and
  • Noriyuki Matsukawa
  • + 3 authors

28 October 2019

The cholinergic efferent network from the medial septal nucleus to the hippocampus has an important role in learning and memory processes. This cholinergic projection can generate theta oscillations in the hippocampus to efficiently encode novel info...

  • Article
  • Open Access
19 Citations
4,219 Views
26 Pages

Green Hydrogels Composed of Sodium Mannuronate/Guluronate, Gelatin and Biointeractive Calcium Silicates/Dicalcium Phosphate Dihydrate Designed for Oral Bone Defects Regeneration

  • Maria Giovanna Gandolfi,
  • Fausto Zamparini,
  • Sabrina Valente,
  • Greta Parchi,
  • Gianandrea Pasquinelli,
  • Paola Taddei and
  • Carlo Prati

18 December 2021

Innovative green, eco-friendly, and biologically derived hydrogels for non-load bearing bone sites were conceived and produced. Natural polysaccharides (copolymers of sodium D-mannuronate and L-guluronate) with natural polypeptides (gelatin) and bioa...

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