Skip to Content

50 Results Found

  • Article
  • Open Access
4 Citations
3,454 Views
11 Pages

The BRAF P.V600E Mutation Status of Melanoma Lung Metastases Cannot Be Discriminated on Computed Tomography by LIDC Criteria nor Radiomics Using Machine Learning

  • Lindsay Angus,
  • Martijn P. A. Starmans,
  • Ana Rajicic,
  • Arlette E. Odink,
  • Mathilde Jalving,
  • Wiro J. Niessen,
  • Jacob J. Visser,
  • Stefan Sleijfer,
  • Stefan Klein and
  • Astrid A. M. van der Veldt

1 April 2021

Patients with BRAF mutated (BRAF-mt) metastatic melanoma benefit significantly from treatment with BRAF inhibitors. Currently, the BRAF status is determined on archival tumor tissue or on fresh tumor tissue from an invasive biopsy. The aim of this st...

  • Review
  • Open Access
121 Citations
11,782 Views
11 Pages

The aim of this study was to provide an overview of the literature available on machine learning (ML) algorithms applied to the Lung Image Database Consortium Image Collection (LIDC-IDRI) database as a tool for the optimization of detecting lung nodu...

  • Review
  • Open Access
63 Citations
7,788 Views
14 Pages

The Performance of Deep Learning Algorithms on Automatic Pulmonary Nodule Detection and Classification Tested on Different Datasets That Are Not Derived from LIDC-IDRI: A Systematic Review

  • Dana Li,
  • Bolette Mikela Vilmun,
  • Jonathan Frederik Carlsen,
  • Elisabeth Albrecht-Beste,
  • Carsten Ammitzbøl Lauridsen,
  • Michael Bachmann Nielsen and
  • Kristoffer Lindskov Hansen

The aim of this study was to systematically review the performance of deep learning technology in detecting and classifying pulmonary nodules on computed tomography (CT) scans that were not from the Lung Image Database Consortium and Image Database R...

  • Article
  • Open Access
52 Citations
12,322 Views
30 Pages

Predicting Radiological Panel Opinions Using a Panel of Machine Learning Classifiers

  • Dmitriy Zinovev,
  • Daniela Raicu,
  • Jacob Furst and
  • Samuel G. Armato III

30 November 2009

This paper uses an ensemble of classifiers and active learning strategies to predict radiologists’ assessment of the nodules of the Lung Image Database Consortium (LIDC). In particular, the paper presents machine learning classifiers that model agree...

  • Article
  • Open Access
10 Citations
4,844 Views
16 Pages

18 April 2024

Enhancing lung cancer diagnosis requires precise early detection methods. This study introduces an automated diagnostic system leveraging computed tomography (CT) scans for early lung cancer identification. The main approach is the integration of thr...

  • Article
  • Open Access
2 Citations
2,547 Views
23 Pages

Lung cancer is by far the leading cause of cancer death among both men and women, making up almost 25% of all cancer deaths Each year, more people die of lung cancer than colon, breast, and prostate cancer combined. The early detection of lung cancer...

  • Communication
  • Open Access
11 Citations
4,348 Views
16 Pages

Soft and flexible strain sensors are becoming popular for many robotic applications. This article presents a stretchable capacitive sensor by combining a conductive filler of carbon black with elastomers and implementing shielding to reduce parasitic...

  • Article
  • Open Access
421 Views
18 Pages

9 December 2025

Energy efficiency in road lighting is increasingly critical for sustainable urban development, yet numerical indicators essential for objective evaluation are often misunderstood or misapplied. This paper addresses fundamental misconceptions in inter...

  • Article
  • Open Access
6 Citations
3,349 Views
19 Pages

Active Semi-Supervised Learning via Bayesian Experimental Design for Lung Cancer Classification Using Low Dose Computed Tomography Scans

  • Phuong Nguyen,
  • Ankita Rathod,
  • David Chapman,
  • Smriti Prathapan,
  • Sumeet Menon,
  • Michael Morris and
  • Yelena Yesha

15 March 2023

We introduce an active, semisupervised algorithm that utilizes Bayesian experimental design to address the shortage of annotated images required to train and validate Artificial Intelligence (AI) models for lung cancer screening with computed tomogra...

  • Article
  • Open Access
13 Citations
4,012 Views
14 Pages

Lung Nodule CT Image Segmentation Model Based on Multiscale Dense Residual Neural Network

  • Xinying Zhang,
  • Shanshan Kong,
  • Yang Han,
  • Baoshan Xie and
  • Chunfeng Liu

10 March 2023

To solve the problem of the low segmentation accuracy of lung nodule CT images using U-Net, an improved method for segmentation of lung nodules by U-Net was proposed. Initially, the dense network connection and sawtooth expanded convolution design wa...

  • Article
  • Open Access
119 Citations
7,207 Views
16 Pages

VGG19 Network Assisted Joint Segmentation and Classification of Lung Nodules in CT Images

  • Muhammad Attique Khan,
  • Venkatesan Rajinikanth,
  • Suresh Chandra Satapathy,
  • David Taniar,
  • Jnyana Ranjan Mohanty,
  • Usman Tariq and
  • Robertas Damaševičius

26 November 2021

Pulmonary nodule is one of the lung diseases and its early diagnosis and treatment are essential to cure the patient. This paper introduces a deep learning framework to support the automated detection of lung nodules in computed tomography (CT) image...

  • Brief Report
  • Open Access
12 Citations
3,673 Views
11 Pages

Pulmonary Nodule Detection and Classification Using All-Optical Deep Diffractive Neural Network

  • Junjie Shao,
  • Lingxiao Zhou,
  • Sze Yan Fion Yeung,
  • Ting Lei,
  • Wanlong Zhang and
  • Xiaocong Yuan

9 May 2023

A deep diffractive neural network (D2NN) is a fast optical computing structure that has been widely used in image classification, logical operations, and other fields. Computed tomography (CT) imaging is a reliable method for detecting and analyzing...

  • Article
  • Open Access
2 Citations
3,047 Views
38 Pages

AI-Driven Bayesian Deep Learning for Lung Cancer Prediction: Precision Decision Support in Big Data Health Informatics

  • Natalia Amasiadi,
  • Maria Aslani-Gkotzamanidou,
  • Leonidas Theodorakopoulos,
  • Alexandra Theodoropoulou,
  • George A. Krimpas,
  • Christos Merkouris and
  • Aristeidis Karras

Lung-cancer incidence is projected to rise by 50% by 2035, underscoring the need for accurate yet accessible risk-stratification tools. We trained a Bayesian neural network on 300 annotated chest-CT scans from the public LIDC–IDRI cohort, integ...

  • Article
  • Open Access
38 Citations
5,620 Views
18 Pages

AWEU-Net: An Attention-Aware Weight Excitation U-Net for Lung Nodule Segmentation

  • Syeda Furruka Banu,
  • Md. Mostafa Kamal Sarker,
  • Mohamed Abdel-Nasser,
  • Domenec Puig and
  • Hatem A. Raswan

28 October 2021

Lung cancer is a deadly cancer that causes millions of deaths every year around the world. Accurate lung nodule detection and segmentation in computed tomography (CT) images is a vital step for diagnosing lung cancer early. Most existing systems face...

  • Article
  • Open Access
2 Citations
2,835 Views
12 Pages

6 November 2021

In recent years, medical image segmentation (MIS) has made a huge breakthrough due to the success of deep learning. However, the existing MIS algorithms still suffer from two types of uncertainties: (1) the uncertainty of the plausible segmentation h...

  • Article
  • Open Access
61 Citations
12,127 Views
14 Pages

Lung Nodule Detection in CT Images Using Statistical and Shape-Based Features

  • Noor Khehrah,
  • Muhammad Shahid Farid,
  • Saira Bilal and
  • Muhammad Hassan Khan

24 February 2020

The lung tumor is among the most detrimental kinds of malignancy. It has a high occurrence rate and a high death rate, as it is frequently diagnosed at the later stages. Computed Tomography (CT) scans are broadly used to distinguish the disease; comp...

  • Article
  • Open Access
37 Citations
7,767 Views
25 Pages

Efficient Pre-Processing and Segmentation for Lung Cancer Detection Using Fused CT Images

  • Imran Nazir,
  • Ihsan Ul Haq,
  • Muhammad Mohsin Khan,
  • Muhammad Bilal Qureshi,
  • Hayat Ullah and
  • Sharjeel Butt

Over the last two decades, radiologists have been using multi-view images to detect tumors. Computer Tomography (CT) imaging is considered as one of the reliable imaging techniques. Many medical-image-processing techniques have been developed to diag...

  • Article
  • Open Access
9 Citations
2,877 Views
32 Pages

18 November 2022

Lung cancer is the leading cancer type that causes mortality in both men and women. Computer-aided detection (CAD) and diagnosis systems can play a very important role for helping physicians with cancer treatments. This study proposes a hierarchical...

  • Article
  • Open Access
10 Citations
2,861 Views
21 Pages

Multi-View Soft Attention-Based Model for the Classification of Lung Cancer-Associated Disabilities

  • Jannatul Ferdous Esha,
  • Tahmidul Islam,
  • Md. Appel Mahmud Pranto,
  • Abrar Siam Borno,
  • Nuruzzaman Faruqui,
  • Mohammad Abu Yousuf,
  • AKM Azad,
  • Asmaa Soliman Al-Moisheer,
  • Naif Alotaibi and
  • Mohammad Ali Moni
  • + 1 author

14 October 2024

Background: The detection of lung nodules at their early stages may significantly enhance the survival rate and prevent progression to severe disability caused by advanced lung cancer, but it often requires manual and laborious efforts for radiologis...

  • Article
  • Open Access
80 Citations
7,590 Views
16 Pages

17 October 2018

Lung cancer is one of the highest causes of cancer-related death in both men and women. Therefore, various diagnostic methods for lung nodules classification have been proposed to implement the early detection. Due to the limited amount and diversity...

  • Article
  • Open Access
8 Citations
3,587 Views
18 Pages

Lung segmentation of chest X-ray (CXR) images is a fundamental step in many diagnostic applications. Most lung field segmentation methods reduce the image size to speed up the subsequent processing time. Then, the low-resolution result is upsampled t...

  • Article
  • Open Access
11 Citations
2,808 Views
12 Pages

28 November 2022

In medical image processing, accurate segmentation of lung tumors is very important. Computer-aided accurate segmentation can effectively assist doctors in surgery planning and treatment decisions. Although the accurate segmentation results of lung t...

  • Article
  • Open Access
61 Citations
5,082 Views
16 Pages

An Efficient DA-Net Architecture for Lung Nodule Segmentation

  • Muazzam Maqsood,
  • Sadaf Yasmin,
  • Irfan Mehmood,
  • Maryam Bukhari and
  • Mucheol Kim

22 June 2021

A typical growth of cells inside tissue is normally known as a nodular entity. Lung nodule segmentation from computed tomography (CT) images becomes crucial for early lung cancer diagnosis. An issue that pertains to the segmentation of lung nodules i...

  • Article
  • Open Access
72 Citations
5,141 Views
13 Pages

9 April 2020

Lung cancer is one of the common causes of cancer deaths. Early detection and treatment of lung cancer is essential. However, the detection of lung cancer in patients produces many false positives. Therefore, increasing the accuracy of the classifica...

  • Article
  • Open Access
25 Citations
3,936 Views
15 Pages

Adaptive Aggregated Attention Network for Pulmonary Nodule Classification

  • Kai Xia,
  • Jianning Chi,
  • Yuan Gao,
  • Yang Jiang and
  • Chengdong Wu

10 January 2021

Lung cancer has one of the highest cancer mortality rates in the world and threatens people’s health. Timely and accurate diagnosis can greatly reduce the number of deaths. Therefore, an accurate diagnosis system is extremely important. The exi...

  • Article
  • Open Access
48 Citations
9,970 Views
12 Pages

31 May 2019

Chronic wounds impose a significant financial burden for the healthcare system. Currently, assessment and monitoring of hard-to-heal wounds are often based on visual means and measuring the size of the wound. The primary wound dressings must be remov...

  • Article
  • Open Access
8 Citations
4,422 Views
23 Pages

1 February 2023

With frequent climate change related disaster shocks and a huge burden of refugees from neighbor country’s conflict, Bangladesh needs to formulate effective strategies to support its most prospective sectors for ensuring sustainable development...

  • Article
  • Open Access
1 Citations
4,760 Views
22 Pages

The Robust Vessel Segmentation and Centerline Extraction: One-Stage Deep Learning Approach

  • Rostislav Epifanov,
  • Yana Fedotova,
  • Savely Dyachuk,
  • Alexandr Gostev,
  • Andrei Karpenko and
  • Rustam Mullyadzhanov

The accurate segmentation of blood vessels and centerline extraction are critical in vascular imaging applications, ranging from preoperative planning to hemodynamic modeling. This study introduces a novel one-stage method for simultaneous vessel seg...

  • Article
  • Open Access
17 Citations
3,554 Views
22 Pages

Computer-Assisted Image Processing System for Early Assessment of Lung Nodule Malignancy

  • Ahmed Shaffie,
  • Ahmed Soliman,
  • Amr Eledkawy,
  • Victor van Berkel and
  • Ayman El-Baz

22 February 2022

Lung cancer is one of the most dreadful cancers, and its detection in the early stage is very important and challenging. This manuscript proposes a new computer-aided diagnosis system for lung cancer diagnosis from chest computed tomography scans. Th...

  • Article
  • Open Access
134 Citations
21,848 Views
18 Pages

An Effective Method for Lung Cancer Diagnosis from CT Scan Using Deep Learning-Based Support Vector Network

  • Imran Shafi,
  • Sadia Din,
  • Asim Khan,
  • Isabel De La Torre Díez,
  • Ramón del Jesús Palí Casanova,
  • Kilian Tutusaus Pifarre and
  • Imran Ashraf

6 November 2022

The diagnosis of early-stage lung cancer is challenging due to its asymptomatic nature, especially given the repeated radiation exposure and high cost of computed tomography(CT). Examining the lung CT images to detect pulmonary nodules, especially th...

  • Article
  • Open Access
9 Citations
3,569 Views
15 Pages

20 September 2024

In the computer-aided diagnosis of lung cancer, the automatic segmentation of pulmonary nodules and the classification of benign and malignant tumors are two fundamental tasks. However, deep learning models often overlook the potential benefits of ta...

  • Article
  • Open Access
15 Citations
2,679 Views
12 Pages

28 December 2022

Intelligent lung nodules classification is a meaningful and challenging research topic for early precaution of lung cancers, which aims to diagnose the malignancy of candidate nodules from the pulmonary computed tomography images. Nowadays, deep lear...

  • Article
  • Open Access
7 Citations
3,228 Views
20 Pages

Early detection is crucial for the survival and recovery of lung cancer patients. Computer-aided diagnosis system can assist in the early diagnosis of lung cancer by providing decision support. While deep learning methods are increasingly being appli...

  • Article
  • Open Access
1 Citations
1,367 Views
27 Pages

ReAcc_MF: Multimodal Fusion Model with Resource-Accuracy Co-Optimization for Screening Blasting-Induced Pulmonary Nodules in Occupational Health

  • Junhao Jia,
  • Qian Jia,
  • Jianmin Zhang,
  • Meilin Zheng,
  • Junze Fu,
  • Jinshan Sun,
  • Zhongyuan Lai and
  • Dan Gui

31 May 2025

Occupational health monitoring in demolition environments requires precise detection of blast-dust-induced pulmonary pathologies. However, it is often hindered by challenges such as contaminated imaging biomarkers, limited access to medical resources...

  • Article
  • Open Access
3 Citations
2,467 Views
14 Pages

Rule-Based Pruning and In Silico Identification of Essential Proteins in Yeast PPIN

  • Anik Banik,
  • Souvik Podder,
  • Sovan Saha,
  • Piyali Chatterjee,
  • Anup Kumar Halder,
  • Mita Nasipuri,
  • Subhadip Basu and
  • Dariusz Plewczynski

25 August 2022

Proteins are vital for the significant cellular activities of living organisms. However, not all of them are essential. Identifying essential proteins through different biological experiments is relatively more laborious and time-consuming than the c...

  • Article
  • Open Access
13 Citations
3,155 Views
16 Pages

Effective Framework for Pulmonary Nodule Classification from CT Images Using the Modified Gradient Boosting Method

  • Harsha Vardhan Donga,
  • Jaya Sai Aditya Nandan Karlapati,
  • Harsha Sri Sumanth Desineedi,
  • Prakasam Periasamy and
  • Sureshkumar TR

18 August 2022

Lung carcinoma, which is commonly known as lung cancer, is one of the most common cancers throughout the world. Mostly, it is not diagnosed until it has spread, and it is very difficult to treat. Hence, early diagnosis of benign and malignant pulmona...

  • Article
  • Open Access
3 Citations
1,330 Views
31 Pages

CAAF-ResUNet: Adaptive Attention Fusion with Boundary-Aware Loss for Lung Nodule Segmentation

  • Thang Quoc Pham,
  • Thai Hoang Le,
  • Khai Dinh Lai,
  • Dat Quoc Ngo,
  • Tan Van Pham,
  • Quang Hong Hua,
  • Khang Quang Le,
  • Huyen Duy Mai Le and
  • Tuyen Ngoc Lam Nguyen

22 June 2025

Background and Objectives: The accurate segmentation of pulmonary nodules in computed tomography (CT) remains a critical yet challenging task due to variations in nodule size, shape, and boundary ambiguity. This study proposes CAAF-ResUNet (Context-A...

  • Article
  • Open Access
372 Views
17 Pages

Genomic Insights into a Thermophilic Bacillus licheniformis Strain Capable of Degrading Polyethylene Terephthalate Intermediate

  • Pedro Eugenio Sineli,
  • Fernando Gabriel Martínez,
  • Federico Zannier,
  • Luciana Costas,
  • José Horacio Pisa,
  • Analía Álvarez and
  • Cintia Mariana Romero

22 January 2026

Bacillus licheniformis Mb1, a thermophilic strain isolated from the Yungas rainforest in northwestern Argentina, was analyzed through genomic and experimental approaches to explore its biotechnological potential. Phylogenomic analysis confirmed its c...

  • Review
  • Open Access
86 Citations
20,407 Views
49 Pages

Deep learning has emerged as a powerful tool for medical image analysis and diagnosis, demonstrating high performance on tasks such as cancer detection. This literature review synthesizes current research on deep learning techniques applied to lung c...

  • Article
  • Open Access
247 Views
32 Pages

Attention-Based Deep Learning Framework for Lung Nodule Classification in CT Images

  • Vinayak K. Bairagi,
  • Aparna Rajesh Lokhande,
  • Shweta Sadanand Salunkhe,
  • Ekkarat Boonchieng and
  • Preeti Topannavar

28 February 2026

Lung cancer continues to be one of the leading causes of cancer-related deaths worldwide, as pulmonary nodules are often diagnosed at later stages. Therefore, accurate nodule classification is crucial for enabling early detection and supporting timel...

  • Article
  • Open Access
92 Citations
8,245 Views
24 Pages

ResBCDU-Net: A Deep Learning Framework for Lung CT Image Segmentation

  • Yeganeh Jalali,
  • Mansoor Fateh,
  • Mohsen Rezvani,
  • Vahid Abolghasemi and
  • Mohammad Hossein Anisi

3 January 2021

Lung CT image segmentation is a key process in many applications such as lung cancer detection. It is considered a challenging problem due to existing similar image densities in the pulmonary structures, different types of scanners, and scanning prot...

  • Review
  • Open Access
118 Citations
36,650 Views
23 Pages

27 October 2014

Electrical stimulation (ES) has been shown to have beneficial effects in wound healing. It is important to assess the effects of ES on cutaneous wound healing in order to ensure optimization for clinical practice. Several different applications as we...

  • Article
  • Open Access
585 Views
28 Pages

Segmentation-Guided Hybrid Deep Learning for Pulmonary Nodule Detection and Risk Prediction from Multi-Cohort CT Images

  • Gomavarapu Krishna Subramanyam,
  • Kundojjala Srinivas,
  • Veera Venkata Raghunath Indugu,
  • Dedeepya Sai Gondi and
  • Sai Krishna Gaduputi Subbammagari

6 January 2026

Background: Lung cancer screening using low-dose computed tomography (LDCT) demands not only early pulmonary nodule detection but also accurate estimation of malignancy risk. This remains challenging due to subtle nodule appearances, the large number...

  • Article
  • Open Access
298 Citations
19,084 Views
19 Pages

Automated Lung Nodule Detection and Classification Using Deep Learning Combined with Multiple Strategies

  • Nasrullah Nasrullah,
  • Jun Sang,
  • Mohammad S. Alam,
  • Muhammad Mateen,
  • Bin Cai and
  • Haibo Hu

28 August 2019

Lung cancer is one of the major causes of cancer-related deaths due to its aggressive nature and delayed detections at advanced stages. Early detection of lung cancer is very important for the survival of an individual, and is a significant challengi...

  • Article
  • Open Access
23 Citations
3,203 Views
30 Pages

A Novel Method for 3D Lung Tumor Reconstruction Using Generative Models

  • Hamidreza Najafi,
  • Kimia Savoji,
  • Marzieh Mirzaeibonehkhater,
  • Seyed Vahid Moravvej,
  • Roohallah Alizadehsani and
  • Siamak Pedrammehr

20 November 2024

Background: Lung cancer remains a significant health concern, and the effectiveness of early detection significantly enhances patient survival rates. Identifying lung tumors with high precision is a challenge due to the complex nature of tumor struct...

  • Article
  • Open Access
26 Citations
4,327 Views
12 Pages

A Computer-Aided Detection System for the Detection of Lung Nodules Based on 3D-ResNet

  • Jiaxu Ning,
  • Haitong Zhao,
  • Lei Lan,
  • Peng Sun and
  • Yunfei Feng

16 December 2019

In recent years, the research into automatic aided detection systems for pulmonary nodules has been extremely active. Most of the existing studies are based on 2D convolution neural networks, which cannot make full use of computed tomography’s (CT) 3...

  • Feature Paper
  • Article
  • Open Access
21 Citations
4,655 Views
13 Pages

Pre-Training Autoencoder for Lung Nodule Malignancy Assessment Using CT Images

  • Francisco Silva,
  • Tania Pereira,
  • Julieta Frade,
  • José Mendes,
  • Claudia Freitas,
  • Venceslau Hespanhol,
  • José Luis Costa,
  • António Cunha and
  • Hélder P. Oliveira

5 November 2020

Lung cancer late diagnosis has a large impact on the mortality rate numbers, leading to a very low five-year survival rate of 5%. This issue emphasises the importance of developing systems to support a diagnostic at earlier stages. Clinicians use Com...

  • Article
  • Open Access
1,005 Views
24 Pages

5 November 2025

This study addresses the common challenges in medical image segmentation and recognition, including boundary ambiguity, scale variation, and the difficulty of modeling long-range dependencies, by proposing a unified framework based on a hierarchical...

  • Article
  • Open Access
31 Citations
3,715 Views
14 Pages

10 February 2023

Measuring pulmonary nodules accurately can help the early diagnosis of lung cancer, which can increase the survival rate among patients. Numerous techniques for lung nodule segmentation have been developed; however, most of them either rely on the 3D...

  • Article
  • Open Access
55 Citations
6,453 Views
26 Pages

Optimization System Based on Convolutional Neural Network and Internet of Medical Things for Early Diagnosis of Lung Cancer

  • Yossra Hussain Ali,
  • Varghese Sabu Chooralil,
  • Karthikeyan Balasubramanian,
  • Rajasekhar Reddy Manyam,
  • Sekar Kidambi Raju,
  • Ahmed T. Sadiq and
  • Alaa K. Farhan

Recently, deep learning and the Internet of Things (IoT) have been widely used in the healthcare monitoring system for decision making. Disease prediction is one of the emerging applications in current practices. In the method described in this paper...