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  • Article
  • Open Access
10 Citations
5,480 Views
25 Pages

Sex-Biased lncRNA Signature in Fetal Growth Restriction (FGR)

  • Aleksandra Lipka,
  • Jan Pawel Jastrzebski,
  • Lukasz Paukszto,
  • Karol Gustaw Makowczenko,
  • Elzbieta Lopienska-Biernat,
  • Marek Gowkielewicz,
  • Ewa Lepiarczyk,
  • Marta Wiszpolska,
  • Mariusz Krzysztof Majewski and
  • Marta Majewska

16 April 2021

Impaired fetal growth is one of the most important causes of prematurity, stillbirth and infant mortality. The pathogenesis of idiopathic fetal growth restriction (FGR) is poorly understood but is thought to be multifactorial and comprise a range of...

  • Article
  • Open Access
7 Citations
2,441 Views
12 Pages

10 November 2022

Hybrids of fluorinated graphite/MoS2 (FGr@MoS2) were prepared via a hydrothermal method and used as lubricating additives to take full advantage of the synergy between FGr and MoS2 in carbon-fiber-reinforced polymer (CFRP). The results show a 21.6% r...

  • Article
  • Open Access
3 Citations
4,176 Views
14 Pages

Pro- and Anti-Angiogenic Markers as Clinical Tools for Suspected Preeclampsia with and without FGR near Delivery—A Secondary Analysis

  • Kristina Kumer,
  • Adi Sharabi-Nov,
  • Vesna Fabjan Vodušek,
  • Tanja Premru Sršen,
  • Nataša Tul,
  • Teja Fabjan,
  • Hamutal Meiri,
  • Kypros Herodotos Nicolaides and
  • Joško Osredkar

8 February 2021

Objective—the objective of this study was to assess the accuracy of placental growth factor (PlGF), soluble Fms-like Tyrosine Kinase 1 (sFlt-1), and endoglin (sEng) in the diagnosis of suspected preeclampsia (PE) with and without fetal growth restric...

  • Article
  • Open Access
1 Citations
840 Views
14 Pages

Impact of COVID-19 Lockdown on the Incidence of Common Pregnancy Complications—Is the Diagnosis of FGR Made Too Generously?

  • Maximilian Rauh,
  • Silvia Suttner,
  • Claudia Bartl,
  • Marco Weigl,
  • Sven Wellmann,
  • Maurice Kappelmeyer,
  • Börge Schmidt,
  • Maria Emilia Solano and
  • Angela Köninger

19 August 2025

Purpose: In 2020, a lockdown due to COVID-19 was ordered by the German government, resulting in population-wide restrictions. In this retrospective study, we question the extent to which health policy restrictions have influenced medical diagnoses. M...

  • Article
  • Open Access
475 Views
11 Pages

Insights into the Hepatic Arterial Buffer Response in Late-Onset FGR

  • Aziz Kından,
  • Can Ozan Ulusoy,
  • Aykut Kından,
  • Tuğçe Sırma,
  • Aşkın Evren Güler,
  • İsmail Burak Gültekin and
  • Zehra Vural Yılmaz

27 November 2025

Objective: To evaluate hepatic artery Doppler parameters in fetuses with fetal growth restriction (FGR) and to investigate their relationship with composite adverse neonatal outcomes (CANO). Methods: This prospective cohort study included 108 pregnan...

  • Feature Paper
  • Review
  • Open Access
24 Citations
18,819 Views
26 Pages

Diagnosis, Prevention, and Management of Fetal Growth Restriction (FGR)

  • Panagiotis Tsikouras,
  • Panos Antsaklis,
  • Konstantinos Nikolettos,
  • Sonia Kotanidou,
  • Nektaria Kritsotaki,
  • Anastasia Bothou,
  • Sotiris Andreou,
  • Theopi Nalmpanti,
  • Kyriaki Chalkia and
  • Nikolaos Nikolettos
  • + 2 authors

28 June 2024

Fetal growth restriction (FGR), or intrauterine growth restriction (IUGR), is still the second most common cause of perinatal mortality. The factors that contribute to fetal growth restriction can be categorized into three distinct groups: placental,...

  • Article
  • Open Access
6 Citations
4,050 Views
13 Pages

18 July 2021

A 0.5 MW class oxy-fuel boiler was developed to capture CO2 from exhaust gas. We adopted natural gas as the fuel for industrial boilers and identified characteristics different from those of pulverized coal, which has been studied for power plants. W...

  • Article
  • Open Access
6 Citations
5,024 Views
7 Pages

Fetal Umbilical Vein Flow in the Classification of Fetuses with Growth Restriction

  • Daniele Farsetti,
  • Francesca Pometti,
  • Grazia Maria Tiralongo,
  • Damiano Lo Presti,
  • Ilaria Pisani,
  • Giulia Gagliardi,
  • Barbara Vasapollo,
  • Gian Paolo Novelli and
  • Herbert Valensise

Objectives: To assess umbilical vein (UV) blood flow in fetal growth restriction (FGR) and in pregnancy with small for gestational age (SGA) fetus. To evaluate the predictive capacity of UV blood flow (QUV) in the discrimination of SGA fetuses from F...

  • Article
  • Open Access
5 Citations
5,443 Views
15 Pages

Maternal Serum Inhibin-A Augments the Value of Maternal Serum PlGF and of sFlt-1/PlGF Ratio in the Prediction of Preeclampsia and/or FGR Near Delivery—A Secondary Analysis

  • Adi Sharabi-Nov,
  • Tanja Premru Sršen,
  • Kristina Kumer,
  • Vesna Fabjan Vodušek,
  • Teja Fabjan,
  • Nataša Tul,
  • Hamutal Meiri,
  • Kypros H. Nicolaides and
  • Joško Osredkar

Objective: We previously provided evidence to confirm that maternal serum levels of soluble Fms-like tyrosine kinase-1 (sFlt-1), placental growth factor (PlGF), and their ratio are useful tools to direct the management of preeclampsia (PE), fetal gro...

  • Article
  • Open Access
9 Citations
3,757 Views
10 Pages

Impact of Maternal Food Restriction on Heart Proteome in Appropriately Grown and Growth-Restricted Wistar—Rat Offspring

  • Andreas Zouridis,
  • Antigoni Manousopoulou,
  • Anastasios Potiris,
  • Polyxeni-Maria Sarli,
  • Leon Aravantinos,
  • Panagiota Pervanidou,
  • Efthymios Deligeoroglou,
  • Spiros D. Garbis and
  • Makarios Eleftheriades

30 January 2021

Objective: Fetal growth restriction is associated with increased postnatal cardiovascular morbidity. The alterations in heart physiology and structure caused by in utero nutrient deprivation have not been extensively studied. We aim to investigate th...

  • Article
  • Open Access
2 Citations
1,816 Views
24 Pages

Placental Protein Citrullination Signatures Are Modified in Early- and Late-Onset Fetal Growth Restriction

  • Owen R. Vaughan,
  • Kasia Maksym,
  • Sara Hillman,
  • Rebecca N. Spencer,
  • Mariya Hristova,
  • Anna L. David and
  • Sigrun Lange

Fetal growth restriction (FGR) is an obstetric condition most frequently caused by placental dysfunction. It is a major cause of perinatal morbidity with limited treatment options, so identifying the underpinning mechanisms is important. Peptidylargi...

  • Article
  • Open Access
1 Citations
2,626 Views
17 Pages

Rs868058 in the Homeobox Gene HLX Contributes to Early-Onset Fetal Growth Restriction

  • Wioletta Izabela Wujcicka,
  • Marian Kacerovsky,
  • Michał Krekora,
  • Piotr Kaczmarek,
  • Beata Leśniczak and
  • Mariusz Grzesiak

16 March 2022

Fetal growth restriction (FGR) is a condition that characterizes fetuses as too small for their gestational age, with an estimated fetal weight (EFW) below the 10th percentile and abnormal Doppler parameters and/or with EFW below the 3rd percentile....

  • Article
  • Open Access
7 Citations
3,835 Views
17 Pages

Integrated Placental Modelling of Histology with Gene Expression to Identify Functional Impact on Fetal Growth

  • Hannah Ee Juen Yong,
  • Katarzyna Maksym,
  • Muhammad Ashraf Bin Yusoff,
  • Esteban Salazar-Petres,
  • Tatiana Nazarenko,
  • Alexey Zaikin,
  • Anna L. David,
  • Sara L. Hillman and
  • Amanda N. Sferruzzi-Perri

6 April 2023

Fetal growth restriction (FGR) is a leading cause of perinatal morbidity and mortality. Altered placental formation and functional capacity are major contributors to FGR pathogenesis. Relating placental structure to function across the placenta in he...

  • Article
  • Open Access
5 Citations
3,429 Views
10 Pages

Brain-Derived Neurotrophic Factor Levels in Cord Blood from Growth Restricted Fetuses with Doppler Alteration Compared to Adequate for Gestational Age Fetuses

  • Jara Pascual-Mancho,
  • Pilar Pintado-Recarte,
  • Jorge C. Morales-Camino,
  • Carlos Romero-Román,
  • Concepción Hernández-Martin,
  • Coral Bravo,
  • Julia Bujan,
  • Melchor Alvarez-Mon,
  • Miguel A. Ortega and
  • Juan De León-Luis

25 January 2022

Background and Objectives: Fetal growth restriction (FGR) is a severe obstetric disease characterized by a low fetal size entailing a set of undesired consequences. For instance, previous studies have noticed a worrisome association between FGR with...

  • Article
  • Open Access
4 Citations
1,887 Views
20 Pages

26 June 2023

FGR is a complication of pregnancy in which the fetus does not reach its programmed growth potential due to placental reasons and it is the single largest risk factor of stillbirth. Babies with FGR are at increased risk of mortality and morbidity not...

  • Article
  • Open Access
2 Citations
2,114 Views
9 Pages

17 February 2023

Objective: We opted to investigate whether fetal growth restriction (FGR) in dichorionic–diamniotic twins is a risk factor for long-term cardiovascular morbidity in offspring. Study design: A population-based retrospective cohort study, compari...

  • Article
  • Open Access
410 Views
14 Pages

Comparative Diagnostic Assessment of Karyotyping, Microarray, and Whole Exome Sequencing in Genetically Associated Fetal Growth Restriction

  • Libing Luo,
  • Chunchun Chen,
  • Cindy Ka Yee Cheung,
  • Yanyan Li,
  • Xiaoying Dai,
  • Ting Zeng and
  • Ying Wang

Background: Fetal growth restriction (FGR) is a significant obstetric complication associated with increased perinatal morbidity and long-term developmental risks. Despite advances in prenatal diagnosis, the genetic etiology of isolated FGR remains i...

  • Review
  • Open Access
710 Views
10 Pages

19 December 2025

Background/Objectives: Fetal growth restriction (FGR), formerly known as intrauterine growth retardation (IUGR), is defined as a fetus’ failure to reach its genetically predetermined growth potential. FGR has also been implicated in the develop...

  • Article
  • Open Access
10 Citations
3,408 Views
16 Pages

8 October 2020

Overproduction of reactive oxygen species (ROS) and, as a result, uncontrolled oxidative stress (OS) can play a central role in disorders of fetal hemodynamics and subsequent development of adverse perinatal outcomes in newborns with fetal growth res...

  • Article
  • Open Access
1 Citations
2,664 Views
19 Pages

18 September 2023

Fission gas plays a significant role in fuel rod performance following accidents. The amount of fission gas increases dramatically under accidental conditions. This leads to a subsequent rise in the fuel rod internal pressure and temperature due to a...

  • Article
  • Open Access
6 Citations
3,486 Views
14 Pages

12 April 2022

Background: Fetal growth restriction (FGR) increases the risk of intrauterine fetal death, infant death and complications in childhood, and diseases that appear in adulthood. Vitamin D may affect fetal vascular flow. The aim of the study was to check...

  • Article
  • Open Access
4 Citations
3,132 Views
16 Pages

Hippocampal mTOR Dysregulation and Morphological Changes in Male Rats after Fetal Growth Restriction

  • Charlotte Schömig,
  • Laura Oberholz,
  • Gregor Fink,
  • Jenny Voggel,
  • Maria Wohlfarth,
  • Jörg Dötsch,
  • Kai-Dietrich Nüsken and
  • Eva Nüsken

20 January 2022

Fetal growth restriction (FGR) has been linked to long-term neurocognitive impairment, especially in males. To determine possible underlying mechanisms, we examined hippocampal cellular composition and mTOR signaling of male rat FGR offspring during...

  • Article
  • Open Access
432 Views
14 Pages

Integrative Analysis of Placental Methylomes Identifies Epigenetically Regulated Genes Implicated in Fetal Growth Restriction

  • Magdalena Bednarek-Jędrzejek,
  • Olga Taryma-Leśniak,
  • Małgorzata Poniatowska,
  • Mateusz Cejko,
  • Katarzyna Maksym,
  • Sylwia Dzidek,
  • Małgorzata Blatkiewicz,
  • Ewa Kwiatkowska,
  • Andrzej Torbé and
  • Sebastian Kwiatkowski

31 January 2026

Fetal growth restriction (FGR) is a major contributor to perinatal morbidity and mortality, most commonly arising from placental dysfunction, with increasing evidence implicating aberrant DNA methylation in its pathogenesis. To identify robust epigen...

  • Article
  • Open Access
5 Citations
2,860 Views
13 Pages

Fetal growth restriction (FGR) is a complication of pregnancy connected with increased risk of intrauterine fetal demise. To increase the diagnostic accuracy, the cerebral placental ratio (CPR) is used. Vitamin D may play a role in the regulation of...

  • Article
  • Open Access
9 Citations
2,861 Views
10 Pages

Circulating SPINT1 Is Reduced in a Preeclamptic Cohort with Co-Existing Fetal Growth Restriction

  • Ciara N. Murphy,
  • Catherine A. Cluver,
  • Susan P. Walker,
  • Emerson Keenan,
  • Roxanne Hastie,
  • Teresa M. MacDonald,
  • Natalie J. Hannan,
  • Fiona C. Brownfoot,
  • Ping Cannon and
  • Tu’uhevaha J. Kaitu’u-Lino
  • + 1 author

9 February 2022

Fetal growth restriction (FGR), when undetected antenatally, is the biggest risk factor for preventable stillbirth. Maternal circulating SPINT1 is reduced in pregnancies, which ultimately deliver small for gestational age (SGA) infants at term (birth...

  • Article
  • Open Access
18 Citations
3,828 Views
17 Pages

Comparative Analysis of the Placental Microbiome in Pregnancies with Late Fetal Growth Restriction versus Physiological Pregnancies

  • Aleksandra Stupak,
  • Tomasz Gęca,
  • Anna Kwaśniewska,
  • Radosław Mlak,
  • Paweł Piwowarczyk,
  • Robert Nawrot,
  • Anna Goździcka-Józefiak and
  • Wojciech Kwaśniewski

A comparative analysis of the placental microbiome in pregnancies with late fetal growth restriction (FGR) was performed with normal pregnancies to assess the impact of bacteria on placental development and function. The presence of microorganisms in...

  • Article
  • Open Access
15 Citations
4,271 Views
11 Pages

Maternal Antioxidant Status in Early Pregnancy and Development of Fetal Complications in Twin Pregnancies: A Pilot Study

  • David Ramiro-Cortijo,
  • María de la Calle,
  • Pilar Rodríguez-Rodríguez,
  • Ángel L. López de Pablo,
  • María R. López-Giménez,
  • Yolanda Aguilera,
  • María A. Martín-Cabrejas,
  • María del Carmen González and
  • Silvia M. Arribas

Twin pregnancies are increasing due to the rise in mothers’ childbearing age and have a higher risk of fetal growth restriction (FGR) and prematurity. Therefore, early prediction of these events is important. Our aim was to analyze in the first...

  • Article
  • Open Access
3 Citations
5,599 Views
10 Pages

Impact of Placental Grading on Pregnancy Outcomes: A Retrospective Cohort Study

  • Antonios Siargkas,
  • Ioannis Tsakiridis,
  • Georgios Michos,
  • Anastasios Liberis,
  • Sofoklis Stavros,
  • Menelaos Kyriakakis,
  • Ekaterini Domali,
  • Apostolos Mamopoulos and
  • Themistoklis Dagklis

Background: Placental grading remains underutilized in clinical practice despite its potential prognostic value. This study aimed to elucidate the relationship between premature placental calcification (PPC) and relevant perinatal outcomes in a large...

  • Article
  • Open Access
5 Citations
2,773 Views
17 Pages

Precision Diagnostics by Affinity-Mass Spectrometry: A Novel Approach for Fetal Growth Restriction Screening during Pregnancy

  • Charles A. Okai,
  • Manuela Russ,
  • Manja Wölter,
  • Kristin Andresen,
  • Werner Rath,
  • Michael O. Glocker and
  • Ulrich Pecks

Fetal growth restriction (FGR) affects about 3% to 8% of pregnancies, leading to higher perinatal mortality and morbidity. Current strategies for detecting fetal growth impairment are based on ultrasound inspections. However, antenatal detection rate...

  • Systematic Review
  • Open Access
15 Citations
5,375 Views
15 Pages

Evidence of Placental Aging in Late SGA, Fetal Growth Restriction and Stillbirth—A Systematic Review

  • Anna Kajdy,
  • Dorota Sys,
  • Jan Modzelewski,
  • Joanna Bogusławska,
  • Aneta Cymbaluk-Płoska,
  • Ewa Kwiatkowska,
  • Magdalena Bednarek-Jędrzejek,
  • Dariusz Borowski,
  • Katarzyna Stefańska and
  • Sebastian Kwiatkowski
  • + 4 authors

During pregnancy, the placenta undergoes a natural aging process, which is considered normal. However, it has been hypothesized that an abnormally accelerated and premature aging of the placenta may contribute to placenta-related health issues. Place...

  • Article
  • Open Access
4 Citations
5,954 Views
10 Pages

Changes in Artery Diameters and Fetal Growth in Cases of Isolated Single Umbilical Artery

  • Elena Contro,
  • Laura Larcher,
  • Jacopo Lenzi,
  • Marina Valeriani,
  • Antonio Farina and
  • Eric Jauniaux

Background—There are conflicting data in the international literature on the risks of abnormal fetal growth in fetuses presenting an isolated single umbilical artery (SUA), and the pathophysiology of this complication is poorly understood. Obje...

  • Article
  • Open Access
7 Citations
2,711 Views
10 Pages

The aim of the study was to assess the role of concentrations of interleukin-17 (IL-17), placental growth factor (PlGF) and soluble endoglin (sENG), as well as the PlGF/sENG ratio in pregnancy complicated by pre-eclampsia (PE) and normal pregnancy. T...

  • Article
  • Open Access
240 Views
13 Pages

Midtrimester Evaluation of Fetal Heart with Fetal Heart Quantification (FetalHQ) Related to Maternal Pathology

  • Stefano Raffaele Giannubilo,
  • Camilla Grelloni,
  • Alessandro Cecchi,
  • Elisa Carboni,
  • Giuseppe Maria Maruotti,
  • Sara Mannolini,
  • Alessia Maria Merone,
  • Maria Terrone and
  • Andrea Ciavattini

9 February 2026

Background: Echocardiography currently represents the gold standard for the anatomical and functional assessment of the fetal heart by experienced operators. FetalHQ (VolusonTM) provides a semi-automated speckle-tracking analysis of the fetal heart w...

  • Article
  • Open Access
3 Citations
1,788 Views
13 Pages

Development of Fragrant Thermosensitive Genic Male Sterile Line Rice Using CRISPR/Cas9

  • Tengkui Chen,
  • Na Pu,
  • Menglin Ni,
  • Huabin Xie,
  • Zhe Zhao,
  • Juan Hu,
  • Zhanhua Lu,
  • Wuming Xiao,
  • Zhiqiang Chen and
  • Hui Wang
  • + 1 author

6 February 2025

This study aimed to develop an aromatic thermosensitive genic male sterile (TGMS) line in indica rice using CRISPR/Cas9 technology. The TMS5 and FGR in the high-quality conventional rice variety Huahang 48 were targeted for editing using CRISPR/Cas9...

  • Review
  • Open Access
60 Citations
8,984 Views
20 Pages

The Multifaced Actions of Curcumin in Pregnancy Outcome

  • Giovanni Tossetta,
  • Sonia Fantone,
  • Stefano Raffaele Giannubilo and
  • Daniela Marzioni

17 January 2021

Curcumin, also known as diferuloylmethane, is the main polyphenolic substance present in the rhizomes of Curcuma longa L. This plant showed many beneficial effects and has been used since ancient times for both food and pharmaceutical purposes. Due t...

  • Article
  • Open Access
4 Citations
3,345 Views
10 Pages

Developmental Evaluation of Infants Who Have Received Tadalafil in Utero for Fetal Growth Restriction

  • Shintaro Maki,
  • Ineko Kato,
  • Naosuke Enomoto,
  • Sho Takakura,
  • Masafumi Nii,
  • Kayo Tanaka,
  • Hiroaki Tanaka,
  • Shinsuke Hori,
  • Kana Matsuda and
  • Tomoaki Ikeda
  • + 4 authors

To assess the long-term effects of tadalafil, a therapeutic agent for fetal growth restriction (FGR), we evaluated the developmental progress of 1.5-year-old infants whose mothers had taken tadalafil during pregnancy. Twenty-four infants were assesse...

  • Review
  • Open Access
5,167 Views
19 Pages

Impact of Maternal Smoking on Obstetric and Neonatal Outcomes in Twin Pregnancies: A Narrative Review

  • Cristina Juliá-Burchés,
  • Alicia Martínez-Varea,
  • José Morales-Roselló and
  • Vicente Diago-Almela

2 December 2024

Maternal smoking, including both traditional cigarettes and electronic ones, is a significant modifiable risk factor associated with adverse perinatal outcomes, especially in twin pregnancies. This narrative review aims to explore the impact of mater...

  • Review
  • Open Access
2 Citations
10,789 Views
22 Pages

Pulmonary Hemorrhage in Premature Infants: Pathophysiology, Risk Factors and Clinical Management

  • Sariya Sahussarungsi,
  • Anie Lapointe,
  • Andréanne Villeneuve,
  • Audrey Hebert,
  • Nina Nouraeyan,
  • Satyan Lakshminrusimha,
  • Yogen Singh,
  • Christine Sabapathy,
  • Tiscar Cavallé-Garrido and
  • Gabriel Altit
  • + 1 author

Pulmonary hemorrhage (PH) is a life-threatening complication predominantly affecting preterm infants, particularly those with very low birth weight (VLBW) and fetal growth restriction (FGR). Typically occurring within the first 72 h of life, PH is ch...

  • Article
  • Open Access
1,601 Views
16 Pages

Prediction of Small for Gestational Age and Growth-Restricted Neonates at 35 to 36 Weeks of Gestation: A Multicenter Cohort Study

  • Raquel Martin-Alonso,
  • Catalina de Paco Matallana,
  • Nuria Valiño,
  • Petya Chaveeva,
  • Themistoklis Dagklis,
  • Antonios Siargkas,
  • Alan Wright,
  • Mario Camacho,
  • Valeria Rolle and
  • Maria M. Gil
  • + 1 author

8 September 2025

Background and Objectives: Third-trimester screening is widely used to identify small for gestational age (SGA) and fetal growth restriction (FGR), but optimal models and timing remain under investigation. This study aimed to assess the performance o...

  • Abstract
  • Open Access
1,807 Views
1 Page

Taxus baccata (European yew) is native to Greece, which hosts the most southeastern populations of the species. It is a medically interesting conifer due to its tetracyclic diterpenes, with the anticancer agent paclitaxel (taxol) being the most well-...

  • Article
  • Open Access
1 Citations
1,939 Views
14 Pages

The Effects of Prenatal Pravastatin Treatment in the Rabbit Fetal Growth Restriction Model

  • Katerina Zapletalova,
  • Ignacio Valenzuela,
  • Marnel Greyling,
  • Yannick Regin,
  • Cristian Frigolett,
  • Ladislav Krofta,
  • Jan Deprest and
  • Johannes van der Merwe

30 September 2023

Fetal growth restriction (FGR) remains without an effective prenatal treatment. Evidence from murine FGR models suggests a beneficial effect of prenatal pravastatin. Since the rabbit hemodichorial placenta more closely resembles the human condition,...

  • Article
  • Open Access
16 Citations
6,477 Views
14 Pages

Selective Fetal Growth Restriction in Dichorionic Twin Pregnancies: Diagnosis, Natural History, and Perinatal Outcome

  • Nikolaos Antonakopoulos,
  • Petra Pateisky,
  • Becky Liu,
  • Erkan Kalafat,
  • Baskaran Thilaganathan and
  • Asma Khalil

This study aims to evaluate the natural history, disease progression, and outcomes in dichorionic twins with selective fetal growth restriction (sFGR) according to different diagnostic criteria and time of onset. Dichorionic twins seen from the first...

  • Article
  • Open Access
1 Citations
1,309 Views
13 Pages

Placental Shear Wave Elastography Assessment in Early and Late Fetal Growth Restriction

  • Erika Cavanagh,
  • Kylie Crawford,
  • Jesrine Hong,
  • Davide Fontanarosa,
  • Christopher Edwards,
  • Marie-Luise Wille,
  • Jennifer Hong,
  • Vicki L. Clifton and
  • Sailesh Kumar

14 July 2025

Background/Objectives: The application of shear wave elastography (SWE) for the assessment of placental disease is still unproven and there is limited data correlating placental biomechanical properties with aberrations in fetal growth. This study in...

  • Article
  • Open Access
4 Citations
2,383 Views
12 Pages

Fetal Left Ventricle Function Evaluated by Two-Dimensional Speckle-Tracking Echocardiography across Clinical Stages of Severity in Growth-Restricted Fetuses

  • Carla Domínguez-Gallardo,
  • Nuria Ginjaume-García,
  • Johana Ullmo,
  • Juan Parra,
  • Ana Vázquez,
  • Mónica Cruz-Lemini and
  • Elisa Llurba

Fetal growth restriction (FGR) can result in adverse perinatal outcomes due to cardiac dysfunction. This study used 2D speckle-tracking echocardiography to assess left ventricle (LV) longitudinal strain across FGR severity stages. A prospective longi...

  • Article
  • Open Access
5 Citations
5,123 Views
15 Pages

Fetal Ultrasound and Magnetic Resonance Imaging Abnormalities in Congenital Cytomegalovirus Infection Associated with and without Fetal Growth Restriction

  • Kenji Tanimura,
  • Akiko Uchida,
  • Mizuki Uenaka,
  • Hitomi Imafuku,
  • Shinya Tairaku,
  • Hiromi Hashimura,
  • Yoshiko Ueno,
  • Takumi Kido and
  • Kazumichi Fujioka

Congenital cytomegalovirus infection (cCMV) can cause fetal growth restriction (FGR) and severe sequelae in affected infants. Clinicians generally suspect cCMV based on multiple ultrasound (US) findings associated with cCMV. However, no studies have...

  • Review
  • Open Access
6 Citations
3,862 Views
18 Pages

21 November 2023

Fetal growth restriction (FGR) is a pathological state that represents a fetus’s inability to achieve adequate growth during pregnancy. Several maternal, placental, and fetal factors are likely associated with FGR etiology. FGR is linked to sev...

  • Article
  • Open Access
9 Citations
5,561 Views
19 Pages

11 June 2020

Pasture-based livestock production is impacted by management and weather. In pastures, there is conflict between leaf retention for plant growth and leaf harvest for animal nutrition. Defoliated pastures with low light interception (LI) may have a lo...

  • Article
  • Open Access
2 Citations
4,178 Views
11 Pages

Neonatal Outcomes of Infants Diagnosed with Fetal Growth Restriction during Late Pregnancy versus after Birth

  • Ohad Houri,
  • Meytal Schwartz Yoskovitz,
  • Asnat Walfisch,
  • Anat Pardo,
  • Yossi Geron,
  • Eran Hadar and
  • Ron Bardin

27 June 2024

Objective: The aim of this study was to investigate the potential differences in the outcomes of neonates in whom FGR was diagnosed late in pregnancy as compared to those in whom growth restriction was diagnosed after birth. Methods: A retrospective...

  • Article
  • Open Access
25 Citations
4,058 Views
11 Pages

Hypertensive Disorders of Pregnancy and Fetal Growth Restriction: Clinical Characteristics and Placental Lesions and Possible Preventive Nutritional Targets

  • Daniela Denis Di Martino,
  • Laura Avagliano,
  • Enrico Ferrazzi,
  • Federica Fusè,
  • Vittoria Sterpi,
  • Marco Parasiliti,
  • Tamara Stampalija,
  • Sara Zullino,
  • Antonio Farina and
  • Francesco D’Ambrosi
  • + 2 authors

10 August 2022

Background: The purpose of this study was to describe the placental lesions in pregnancies complicated by hypertensive disorders (HDP) and/or fetal growth restriction (FGR) and in uneventful control pregnancies. Methods: This is a case control study...

  • Article
  • Open Access
1,079 Views
9 Pages

Re-Evaluating the Contraction Stress Test for Term Fetal Growth Restriction Fetuses: A Retrospective Study

  • Roie Alter,
  • Hagar Herz,
  • Adiel Cohen,
  • Naama Lessans,
  • Yossef Ezra and
  • Doron Kabiri

21 August 2025

Background: Fetal growth restriction (FGR) is associated with increased perinatal morbidity and mortality, yet optimal intrapartum management remains debated. The contraction stress test (CST) has been proposed as a tool to assess fetal tolerance to...

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