A new crAss-like genome encoding diversity-generating retroelement (DGR) was found in the fecal virome of a healthy volunteer. The genome of the phage referred to as the crAssphage LMMB, belonged to the candidate genus I of the AlphacrAssvirinae subf...
Diversity-generating retroelements (DGRs) are prokaryotic systems providing rapid modification and adaptation of target proteins. In phages, the main targets of DGRs are receptor-binding proteins that are usually parts of tail structures and the vari...
An accurate and reliable forecast for traffic flow is regarded as one of the foundational functions in an intelligent transportation system. In this paper, a new model for traffic flow forecasting, named EnGS-DGR, is designed based on ensemble learni...
Diversity-generating retroelements (DGRs) are a unique family of retroelements that confer selective advantages to their hosts by accelerating the evolution of target genes through a specialized, error-prone, reverse transcription process. First ide...
In the development of deep geological repositories (DGRs), performance assessment modeling is used to evaluate the integrity and performance of the engineered and geological barriers for thousands or millions of years of evolution of the disposal sys...
The Asn-Gly-Arg (NGR) motif and its deamidation product isoAsp-Gly-Arg (isoDGR) have recently attracted considerable attention as tumor-targeting ligands. Because an NGR-containing peptide and the corresponding isoDGR-containing peptide target differ...
Neurodegenerative disorders can induce modifications of several proteins; one of which is ceruloplasmin (Cp), a ferroxidase enzyme found modified in the cerebrospinal fluid (CSF) of neurodegenerative diseases patients. Cp modifications are caused by...
Spontaneous deamidation in the Asn-Gly-Arg (NGR) motif that yields an isoAsp-Gly-Arg (isoDGR) sequence has recently attracted considerable attention because of the possibility of application to dual tumor targeting. It is well known that Asn deamidat...
Integrin ligands containing the tripeptide sequences Arg-Gly-Asp (RGD) and iso-Asp-Gly- Arg (isoDGR) were actively investigated as inhibitors of tumor angiogenesis and directing unit in tumor-targeting drug conjugates. Reported herein is the synthesi...
Rice, a staple food for billions around the globe, is cultivated in numerous forms. Among them, soft rice is well known, which is characterized by its tender, creamy consistency and desirable texture. In this study, we examined the physicochemical pr...
Background and Objectives: Although there are many studies that investigate the relationship between duodenogastric reflux (DGR) and Helicobacter pylori in adult patients, the reported data are contradictory. In addition, there are very few studies i...
The Changbei gas field is dominated by wells with large horizontal displacement, which have exhibited high gas production performance at an early stage of development. With the decrease in reservoir pressure, the liquid loading in the gas well is rel...
This work involved the laboratory modeling of biogenic and biogenically mediated corrosion of AISI 304 stainless steel under geochemical conditions representative of the geological disposal of radioactive waste at the Yeniseisky site (Russia). Experi...
This study investigates the performance of two bentonite materials, specifically MX-80 (Na-bentonite) and FEBEX (Ca-Mg-Na-bentonite), employed as engineered barriers in deep geological disposal facilities for the isolation of high-level radioactive w...
In 2013, the Spanish government created two new taxes on used nuclear fuel. This article aims to present the results of an economic study carried out to compare the costs of long-term storage of used nuclear fuel –open cycle strategy–, with the cost...
The deep geological repository (DGR) system has been selected by most of the world’s nuclear waste management organizations for the long-term disposal of radioactive wastes. The DGR mainly consists of a multi-barrier system—comprising the...
Background: Duodenogastric reflux (DGR) is increasingly recognized in children with dyspeptic complaints; however, its association with symptom severity and histopathological gastritis remains unclear. This study aimed to evaluate the relationship be...
The temperature evolution within a deep geological repository (DGR) is a key design consideration for the safe and permanent storage of the high-level radioactive waste contained inside used nuclear fuel containers (UFCs). Due to the material limitat...
The safety and robustness of Deep Geological Repositories (DGRs) are of paramount importance for the long-term management of spent nuclear fuel from electricity generation. The introduction of a multi-barrier system, which includes the host rock form...
Currently, the production of radioactive waste from nuclear industries is increasing, leading to the development of reliable containment strategies. The deep geological repository (DGR) concept has emerged as a suitable storage solution, involving th...
Membrane-tethered sterol-binding Lam/Ltc proteins localize at junctions between the endoplasmic reticulum (ER) membrane and other organelles. Two of the six family members—Lam2/Ltc4 (initially Ysp2) and paralog Lam4/Ltc3—localize to ER-pl...
Road construction consumes great amounts of high-grade natural resources. Using low-grade natural rocks or some solid wastes as substitute materials is a hot topic. Considering this, the feasibility of using low-grade granite aggregate, solid waste-b...
Metabolic diseases have been shown to be associated with low vitamin D status; however, the findings have been inconsistent. Hence, the objective of our study was to investigate the relationship between vitamin D status and metabolic disease-related...
Given the relationship between vitamin D deficiency (VDD) and adverse outcomes of metabolic diseases, we investigated the interplay of dietary and genetic components on vitamin D levels and metabolic traits in young adults from Brazil. Genetic analys...
Objectives: Gastroesophageal reflux disease (GERD) is commonly encountered in adults and children. A subset of patients with GERD are refractory to acid suppressants, implicating other factors in the refluxate. Duodenogastric reflux (DGR) produces si...
The Chao Phraya River basin is located in the central area of Thailand, which experiences many land subsidence issues due to groundwater pumping. The Department of Groundwater Resources (DGR) has been recording data on the changes in the groundwater...
Early growth performances of 11 native tree species were investigated in three different sites in Mindanao, Philippines, to evaluate their adaptability and potential for plantation development. Three alien species were added to assess how native spec...
A typical deep geological repository (DGR) design consists of a multi-barrier system, including the natural host rock and the engineered barrier system. Understanding the swelling behavior of bentonite-based sealing materials (BBSM), as a candidate m...
The Ghanaian population is experiencing an upsurge in obesity and type 2 diabetes (T2D) due to rapid urbanization. Besides dietary factors, vitamin D-related genetic determinants have also been shown to contribute to the development of obesity and T2...
Duodenogastric reflux (DGR) causes bile reflux gastritis (BRG) and may develop into gastric cancer. DGR is classified as primary in non-operated stomachs or secondary to surgical intervention. Primary DGR and Helicobacter pylori (H. pylori) infection...
There are two key issues in the safety assessment of the water distribution system (WDS). One is how to evaluate the safety levels of water supply for customers, while the other is how to describe the importance of a pipe for the global or local WDS....
The model of a graphene (Gr) sheet putting on a silicon (Si) substrate is used to simulate the structures of Si microparticles wrapped up in a graphene cage, which may be the anode of lithium-ion batteries (LIBS) to improve the high-volume expansion...
Controlled environment agriculture technologies are traditionally applied to higher plants to enhance growth and cultivation periods, but such a concept has seldom been applied to seaweed aquaculture. A new dimension has been opened, wherein prelimin...
Intestinal phages are abundant and important components of gut microbiota, yet the isolated and characterized representatives that infect abundant gut bacteria are sparse. Here we describe the isolation of human intestinal phages infecting Bacteroide...
The impressive furtherance of communication technologies has exhorted industrial companies to link-up these developments with their own abilities with the target of efficiency enhancement through smart supervision and control. With this in mind, the...
Gases can potentially generate in a deep geological repository (DGR) for the long-term containment of radioactive waste. Natural and engineered barriers provide containment of the waste by mitigating contaminant migration. However, if gas pressures e...
Real-time acquisition of high-precision 3D spatial information is critical for intelligent maintenance of urban infrastructure. While SLAM technology based on LiDAR–IMU sensor fusion has become a core approach for infrastructure monitoring, its...
With consideration of the intermittency of renewable generation and uncertain load, a regional control strategy is presented to smooth the unscheduled power fluctuation in this letter. Then, an affine arithmetic-based modeling method is proposed to d...
Bacteriophages of the order Crassvirales are highly abundant and near-universal members of the human gut microbiome worldwide. Zeta crAss-like phages comprise a separate group in the order Crassvirales, and their genomes exhibit greater variability t...
Gastrointestinal stromal tumour (GIST) is a disease of older adults and is dominated by KIT/PDGFR mutations. In children, GIST is rare, predominantly occurs in girls, has a stomach location and generally lacks KIT/PDGFR mutations. For young adults (Y...
Gas generation and migration are important processes that must be considered in a safety case for a deep geological repository (DGR) for the long-term containment of radioactive waste. Expansive soils, such as bentonite-based materials, are widely co...
The groundwater level is a significant factor when assessing the sustainability of soil/ground environmental factors, such as bearing capacity behavior and soil surface displacement. Normally, groundwater level changes depend on deep-well pumping in...
The disposal of high-level radioactive waste (HLW) and spent nuclear fuel (SF) presents a unique challenge for the prediction of the long-term performance of corrodible structures since the HLW/SF canisters are expected, in some cases, to have lifeti...
CrAss-like phages play an important role in maintaining ecological balance in the human intestinal microbiome. However, their genetic diversity and lifestyle are still insufficiently studied. In this study, a novel CrAssE-Sib phage genome belonging t...
Bacillus velezensis is a promising candidate for biocontrol applications. A common second messenger molecule, bis-(3,5)-cyclic-dimeric-guanosine monophosphate (c-di-GMP), has the ability to regulate a range of physiological functions that impact the...
In this research, the authors set out to propose a new method of predicting and adjusting the main cutting parameters of chip machining, namely spraying on the substrate. In the experiments, a total of 28 turning cuts on a Stellite 6 coating layer we...
Bentonites from the 10th Khutor deposit (Republic of Khakassia, Russia) are considered a potential buffer material for isolation of radioactive waste in the crystalline rocks of Yeniseyskiy site (Krasnoyarskiy region). This study presents the results...
LiDAR-based Simultaneous Localization and Mapping (SLAM) serves as a fundamental technology for autonomous navigation. However, in complex environments, LiDAR odometry often experience degraded localization accuracy and robustness. This paper propose...
Due to the limitation of a single sensor such as only camera or only LiDAR, the Visual SLAM detects few effective features in the case of poor lighting or no texture. The LiDAR SLAM will also degrade in an unstructured environment and open spaces, wh...
Seaweed aquaculture is affected by natural and anthropogenic stressors, which put the biomass productivity of the cultures at risk. Seaweed biomass for commercial purposes, principally in pharmaceutical and/or nutraceutical applications, needs to be...
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