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1,898 Results Found

  • Article
  • Open Access
12 Citations
3,652 Views
18 Pages

Conventional stabilization/solidification materials have defects in the simultaneous treatment of heavy metals (HMs) and phenanthrene (PHe). In order to solve this problem, a new functional material β-cyclodextrin modified biochar (β-CD-BC)...

  • Article
  • Open Access
16 Citations
5,210 Views
18 Pages

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

  • Hagma H. Workel,
  • Nienke van Rooij,
  • Annechien Plat,
  • Diana C.J. Spierings,
  • Rudolf S. N. Fehrmann,
  • Hans W. Nijman and
  • Marco de Bruyn

Tumor-infiltrating CD8+ T cells (TIL) are of the utmost importance in anti-tumor immunity. CD103 defines tumor-resident memory T cells (TRM cells) associated with improved survival and response to immune checkpoint blockade (ICB) across human tumors....

  • Article
  • Open Access
342 Views
19 Pages

High-Stability Thick-Shell CdZnSeS/CdZnS/ZnS Green-Alloy Quantum Dots in Photoluminescent Diffuser-Plate Masterbatches

  • Ziming Zhou,
  • Dexia Zhou,
  • Ning Li,
  • Ya Liu,
  • Zhaobing Tang,
  • Siqi Jia and
  • Xiao Wei Sun

28 November 2025

As a core component of emerging quantum-dot display technology, the stability of quantum-dot materials is crucial to determining the performance of quantum-dot photoluminescent diffuser plates. This study successfully synthesized high-stability thick...

  • Article
  • Open Access
11 Citations
5,024 Views
14 Pages

Stabilization of the CD81 Large Extracellular Loop with De Novo Disulfide Bonds Improves Its Amenability for Peptide Grafting

  • Stefan Vogt,
  • Gerhard Stadlmayr,
  • Katharina Stadlbauer,
  • Flávio Sádio,
  • Peter Andorfer,
  • Johannes Grillari,
  • Florian Rüker and
  • Gordana Wozniak-Knopp

Tetraspan proteins are significantly enriched in the membranes of exosomal vesicles (EVs) and their extracellular domains are attractive targets for engineering towards specific antigen recognition units. To enhance the tolerance of a tetraspanin fol...

  • Article
  • Open Access
11 Citations
5,253 Views
17 Pages

Exploring the Potential of Water-Soluble Squid Ink Melanin: Stability, Free Radical Scavenging, and Cd2+ Adsorption Abilities

  • Shuji Liu,
  • Xianwei Liu,
  • Xueqin Zhang,
  • Yongchang Su,
  • Xiao’e Chen,
  • Shuilin Cai,
  • Dengyuan Liao,
  • Nan Pan,
  • Jie Su and
  • Xiaoting Chen
  • + 2 authors

30 October 2023

Squid ink melanin can be efficiently extracted from the byproduct ink sac generated during squid processing. As a natural food colorant, it possesses inherent antioxidant properties and the capability to adsorb heavy metals. This study aims to invest...

  • Article
  • Open Access
9 Citations
2,753 Views
14 Pages

11 September 2019

In the present study, the integrated use of organic and inorganic amendments (CS–MD–CSP) including carbide slag (CS), calcium superphosphate (CSP) and mushroom dreg (MD) are employed for the stabilization of heavy metals in contaminated s...

  • Article
  • Open Access
1 Citations
1,376 Views
21 Pages

22 February 2025

CD137 is a prominent costimulatory molecule of the tumor necrosis factor (TNF) receptor superfamily that activates T cells through a complex bidirectional signaling process involving CD137L. The clinical value of immunotherapies underscores the poten...

  • Article
  • Open Access
832 Views
19 Pages

13 June 2025

The influence of petroleum hydrocarbons (PHCs) on the transport and transformation of heavy metals may limit bioremediation efficiency. The mechanisms by which PHC degradation intermediates control heavy metal distribution in calcareous soils from ka...

  • Article
  • Open Access
901 Views
20 Pages

15 September 2025

This study explores the dual functionality of cadmium-based pigments (CdS, CdSe, and CdS1−xSex solid solutions) as historical colorants and visible-light photocatalysts. Synthesized pigments here replicated hues of traditional cadmium reds. At...

  • Article
  • Open Access
1 Citations
1,469 Views
23 Pages

Application of Iron-Bimetal Biochar for As and Cd Reduction and Soil Organic Carbon Preservation Under Varying Moisture

  • Frank Stephano Mabagala,
  • Tingjuan Wang,
  • Qiufen Feng,
  • Xibai Zeng,
  • Chao He,
  • Cuixia Wu,
  • Nan Zhang and
  • Shiming Su

The contamination of paddy soils with arsenic (As) and cadmium (Cd), coupled with the depletion of soil organic carbon (SOC), poses significant threats to rice yields and quality. There is an urgent need to identify a suitable soil additive capable o...

  • Article
  • Open Access
13 Citations
3,517 Views
18 Pages

10 August 2022

Compared to beta-cyclodextrins (beta-CD), hydroxypropyl-beta-cyclodextrins (HP-beta-CD) are a more popular material used to prepare inclusion complexes due to their superior solubility and intestinal absorption. In this study, oleuropein (OL) inclusi...

  • Article
  • Open Access
8 Citations
2,523 Views
13 Pages

12 June 2023

Background: Ginsenoside Rg5 has been proven to possess numerous health benefits. However, Rg5 is difficult to prepare using the current methods, and the poor stability and solubility of Rg5 are intractable properties that limit its application. We tr...

  • Article
  • Open Access
6 Citations
3,993 Views
21 Pages

Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation

  • Jiayi Huang,
  • Shiqi Hong,
  • Lucas Yuan Hao Goh,
  • Hailong Zhang,
  • Tao Peng,
  • Keat Theng Chow,
  • Rajeev Gokhale and
  • Vinod Tuliani

19 April 2024

Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities. KLEPTOSE® HPβCD (hydrox...

  • Article
  • Open Access
6 Citations
2,841 Views
17 Pages

16 August 2022

Oxyresveratrol (Oxy) has attracted much attention by employing it as an antibrowning agent in fruits and vegetables. In this study, the formation of cyclodextrin (CD) inclusion exhibited a certain protective effect on Oxy oxidative degradation, while...

  • Article
  • Open Access
7 Citations
3,163 Views
10 Pages

Performance Comparison of CdTe:Na, CdTe:As, and CdTe:P Single Crystals for Solar Cell Applications

  • Sangsu Kim,
  • Deok Kim,
  • Jinki Hong,
  • Abdallah Elmughrabi,
  • Alima Melis,
  • Jung-Yeol Yeom,
  • Chansun Park and
  • Shinhaeng Cho

14 February 2022

We compared thermal stability, open-circuit voltage, short-circuit current, and fill factor values of single-crystal Cadmium telluride (CdTe) grown using the vertical Bridgman (VB) technique and doped with group V elements (phosphorus and arsenic), a...

  • Article
  • Open Access
13 Citations
3,563 Views
10 Pages

Functional Supramolecular of Inclusion Complex of Herbicide Fluroxypyr with HPβCD

  • Shuang Gao,
  • Chao Bie,
  • Yanyan Liu,
  • Tianyu Zhang,
  • Ying Fu and
  • Fei Ye

22 November 2018

In this study, hydroxypropyl-β-cyclodextrin (HPβCD) was used to form an inclusion complex with fluroxypyr to enhance water solubility and thermal stability. The inclusion complex was prepared by a saturated solution method and characterized...

  • Article
  • Open Access
2 Citations
2,297 Views
26 Pages

Effect of Macrophages and Latent Reservoirs on the Dynamics of HTLV-I and HIV-1 Coinfection

  • A. M. Elaiw,
  • N. H. AlShamrani,
  • E. Dahy,
  • A. A. Abdellatif and
  • Aeshah A. Raezah

22 January 2023

Human immunodeficiency virus type 1 (HIV-1) and human T-lymphotropic virus type I (HTLV-I) are two retroviruses that have a similar fashion of transmission via sharp objects contaminated by viruses, transplant surgery, transfusion, and sexual relatio...

  • Article
  • Open Access
26 Citations
4,027 Views
17 Pages

Cadmium Stabilization and Redox Transformation Mechanism in Maize Using Nanoscale Zerovalent-Iron-Enriched Biochar in Cadmium-Contaminated Soil

  • Sehar Razzaq,
  • Beibei Zhou,
  • Muhammad Zia-ur-Rehman,
  • Muhammad Aamer Maqsood,
  • Saddam Hussain,
  • Ghous Bakhsh,
  • Zhenshi Zhang,
  • Qiang Yang and
  • Adnan Raza Altaf

14 April 2022

Cadmium (Cd) is a readily available metal in the soil matrix, which obnoxiously affects plants and microbiota; thus, its removal has become a global concern. For this purpose, a multifunctional nanoscale zerovalent—iron enriched biochar (nZVI/B...

  • Article
  • Open Access
14 Citations
3,605 Views
19 Pages

Improving Weak Subgrade Soil Using Different Additives

  • M. S. Eisa,
  • M. E. Basiouny,
  • A. Mohamady and
  • M. Mira

24 June 2022

Weak subgrade is the main problem facing most highway projects. Therefore, this study focuses on trying to improve the properties and increase the strength of weak, clayey, swelling soil for use as a subgrade for pavement structural sections. This tr...

  • Article
  • Open Access
43 Citations
5,845 Views
13 Pages

Curcumin–Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer

  • Khaled Greish,
  • Valeria Pittalà,
  • Sebastien Taurin,
  • Safa Taha,
  • Fatemah Bahman,
  • Aanchal Mathur,
  • Anfal Jasim,
  • Fatima Mohammed,
  • Ibrahim M. El-Deeb and
  • Salim Fredericks
  • + 1 author

1 November 2018

Breast cancer is the most common cancer diagnosed among females worldwide. Although breast cancer survival has largely improved in the past 30 years, it remains highly heterogeneous in its response to treatment. Triple-negative breast cancer (TNBC) i...

  • Article
  • Open Access
17 Citations
6,584 Views
10 Pages

Hydrothermal Carbonation Carbon-Coated CdS Nanocomposite with Enhanced Photocatalytic Activity and Stability

  • Yuanliang Ma,
  • Zhongkun Zhao,
  • Zhurui Shen,
  • Qiang Cai,
  • Huiming Ji and
  • Leichao Meng

24 June 2017

Herein, a novel CdS nanocomposite is fabricated by a facile one-pot hydrothermal method assisted by glucose and polyvinylpyrrolidone (PVP). The as-prepared CdS is coated with a thin layer, which is determined to be hydrothermal carbonation carbon (HT...

  • Proceeding Paper
  • Open Access
9 Citations
3,903 Views
13 Pages

26 October 2023

Metal–organic frameworks (MOFs) are a class of material made up of metal ions or clusters and organic linkers. Cyclodextrin-based MOFs (CD-MOFs) are gaining popularity among MOFs due to their unique features, such as high porosity, permanent po...

  • Article
  • Open Access
7 Citations
5,770 Views
15 Pages

Low-Noise Multimodal Reconfigurable Sensor Readout Circuit for Voltage/Current/Resistive/Capacitive Microsensors

  • Donggeun You,
  • Hyungseup Kim,
  • Jaesung Kim,
  • Kwonsang Han,
  • Hyunwoo Heo,
  • Yongsu Kwon,
  • Gyungtae Kim,
  • Woo Suk Sul,
  • Jong Won Lee and
  • Boung Ju Lee
  • + 1 author

2 January 2020

This paper presents a low-noise reconfigurable sensor readout circuit with a multimodal sensing chain for voltage/current/resistive/capacitive microsensors such that it can interface with a voltage, current, resistive, or capacitive microsensor, and...

  • Article
  • Open Access
17 Citations
5,894 Views
26 Pages

Polysorbates versus Hydroxypropyl Beta-Cyclodextrin (HPβCD): Comparative Study on Excipient Stability and Stabilization Benefits on Monoclonal Antibodies

  • Hailong Zhang,
  • Shiqi Hong,
  • Sarah Si Kai Tan,
  • Tao Peng,
  • Lucas Yuan Hao Goh,
  • Kwan Hang Lam,
  • Keat Theng Chow and
  • Rajeev Gokhale

1 October 2022

Polysorbates (PS 20 and PS 80) are the most widely used surfactants in biopharmaceutical formulations to protect proteins from denaturation, aggregation, and surface adsorption. To date, around 70% of marketed therapeutic antibodies contain either PS...

  • Article
  • Open Access
11 Citations
2,738 Views
16 Pages

The effects of Cd, Cd + Fe, and Cd + Ni on the thermophilic anaerobic fermentation of corn stover and cow manure were studied in pilot experiments by investigating the biogas properties, process stability, substrate biodegradation, and microbial prop...

  • Article
  • Open Access
6 Citations
3,089 Views
12 Pages

Incorporation of CD55 into the Zika Viral Envelope Contributes to Its Stability against Human Complement

  • Zahra Malekshahi,
  • Sarah Bernklau,
  • Britta Schiela,
  • Iris Koske,
  • Zoltan Banki,
  • Karin Stiasny,
  • Claire L. Harris,
  • Reinhard Würzner and
  • Heribert Stoiber

19 March 2021

The rapid spread of the virus in Latin America and the association of the infection with microcephaly in newborns or Guillain–Barré Syndrome in adults prompted the WHO to declare the Zika virus (ZIKV) epidemic to be an international public health eme...

  • Article
  • Open Access
38 Citations
9,830 Views
13 Pages

Constructing a MoS2 QDs/CdS Core/Shell Flowerlike Nanosphere Hierarchical Heterostructure for the Enhanced Stability and Photocatalytic Activity

  • Shijing Liang,
  • Zhouming Zhou,
  • Xiuqin Wu,
  • Shuying Zhu,
  • Jinhong Bi,
  • Limin Zhou,
  • Minghua Liu and
  • Ling Wu

15 February 2016

MoS2 quantum dots (QDs)/CdS core/shell nanospheres with a hierarchical heterostructure have been prepared by a simple microwave hydrothermal method. The as-prepared samples are characterized by XRD, TEM, SEM, UV-VIS diffuse reflectance spectra (DRS)...

  • Article
  • Open Access
17 Citations
3,912 Views
12 Pages

20 August 2020

In this paper, efficient and stable photoelectrochemical (PEC) hydrogen (H2) evolution using copper indium sulfide (CuInS2) thin film electrodes was studied. Modification with a cadmium sulfide (CdS) layer led to improved charge separation at the int...

  • Article
  • Open Access
1 Citations
1,085 Views
19 Pages

Neohesperidin (NH), a bioactive flavanone glycoside, exhibits multifaceted pharmacological properties including antioxidant and anti-inflammatory activities. However, its clinical application is severely constrained by inherent physicochemical limita...

  • Article
  • Open Access
11 Citations
2,741 Views
17 Pages

5 February 2023

Fabrication and characterization of hybrid nanomats containing quantum dots can play a prominent role in the development of advanced biosensors and bio-based semiconductors. Owing to their size-dependent properties and controlled nanostructures, quan...

  • Article
  • Open Access
491 Views
12 Pages

Observation of Direct and Indirect Effects of Surface Stabilizer on the Attenuation Coefficient of CdTe Nanoplatelet Films

  • Sergei Bubenov,
  • Aigerim Ospanova,
  • Alexander Vinokurov,
  • Asset Kainarbay,
  • Aizhan Akhmetova,
  • Kirill Cherednichenko,
  • Dulat Daurenbekov and
  • Sergey Dorofeev

7 November 2025

Absorption spectra are widely used in laboratory practice to measure the content of a great variety of colloidal semiconductor nanocrystals. In the case of atomically thin nanoplatelets, only CdSe has been studied enough to allow such quantification,...

  • Article
  • Open Access
20 Citations
4,314 Views
14 Pages

13 March 2019

Three-dimensional PANI/CdSNRs-SiO2 hydrogel (CdS NRs-PANI-SiO2) was synthesized by loading polyaniline (PANI) onto the semiconductor CdS nanorods (NRs) surface and loading the binary complex on SiO2 gel. The structure, optical properties, and electro...

  • Article
  • Open Access
21 Citations
5,913 Views
14 Pages

Interactions between CD147 and cyclophilin A (CypA) promote plaque rupture that causes atherosclerosis-related cardiovascular events, such as myocardial infarction and stroke. Here, we investigated whether SP-8356 ((1S,5R)-4-(3,4-dihydroxy-5-methoxys...

  • Article
  • Open Access
1,260 Views
14 Pages

The complexes of Ephedrine with Nickel, Zinc and Cadmium ions have been investigated spectrophotometricalfy using the method of corresponding solutions [I-3] and pH-metrically using Irving and Rossoti technique [4] Two compositions were observed spec...

  • Article
  • Open Access
7 Citations
3,944 Views
14 Pages

26 February 2018

Decoration of Zn0.15Cd0.85S nanoflowers with P25 for forming P25/Zn0.15Cd0.85S nanocomposite has been successfully synthesized with fine crystallinity by one-step low temperature hydrothermal method. Photocatalytic efficiency of the as-prepared P25/Z...

  • Article
  • Open Access
3 Citations
1,686 Views
14 Pages

In Vitro Stability and Pharmacokinetic Study of Pedunculoside and Its Beta-CD Polymer Inclusion Complex

  • Liang Wu,
  • Danfeng Li,
  • Peijing Wang,
  • Linling Dong,
  • Wang Zhang,
  • Jianjun Xu and
  • Xiaoliang Jin

Pedunculoside, a triterpene saponin derived from various Ilex species, holds potential as a treatment for cardiovascular diseases. However, its clinical application is hindered by poor bioavailability, rapid elimination, and extensive intestinal meta...

  • Article
  • Open Access
3 Citations
2,914 Views
9 Pages

High Stability of Liquid-Typed White Light-Emitting Diode with Zn0.8Cd0.2S White Quantum Dots

  • Chin-Chuan Huang,
  • Kuo-Hsiung Chu,
  • Chin-Wei Sher,
  • Chun-Liang Lin,
  • Yan-Kuin Su,
  • Chia-Wei Sun and
  • Hao-Chung Kuo

2 April 2021

In this study, we demonstrate a new design of white light-emitting diode (WLED) with high stability and luminous efficiency as well as positive aging. Colloidal ternary Zn0.8Cd0.2S (named Zn0.8) white quantum dots (WQDs) were prepared by chemical rou...

  • Review
  • Open Access
6 Citations
2,217 Views
29 Pages

14 June 2024

A review of the state of research in the development of conductometric gas sensors based on II–VI semiconductors is given. It was shown that II–VI compounds indeed have properties that are necessary for the development of highly efficient...

  • Article
  • Open Access
8 Citations
3,870 Views
17 Pages

Enhanced Solubility and Stability of Aripiprazole in Binary and Ternary Inclusion Complexes Using Hydroxy Propyl Beta Cyclodextrin (HPβCD) and L-Arginine

  • Sophia Awais,
  • Nouman Farooq,
  • Sharmeen Ata Muhammad,
  • Hamed A. El-Serehy,
  • Farrah Ishtiaq,
  • Mehwish Afridi,
  • Hina Ahsan,
  • Amin Ullah,
  • Tariq Nadeem and
  • Kishwar Sultana

The low water solubility of an active pharmaceutical ingredient (aripiprazole) is one of the most critical challenges in pharmaceutical research and development. This antipsychotic drug has an inadequate therapeutic impact because of its minimal and...

  • Article
  • Open Access
21 Citations
10,393 Views
11 Pages

TriFabs—Trivalent IgG-Shaped Bispecific Antibody Derivatives: Design, Generation, Characterization and Application for Targeted Payload Delivery

  • Klaus Mayer,
  • Anna-Lena Baumann,
  • Michael Grote,
  • Stefan Seeber,
  • Hubert Kettenberger,
  • Sebastian Breuer,
  • Tobias Killian,
  • Wolfgang Schäfer and
  • Ulrich Brinkmann

17 November 2015

TriFabs are IgG-shaped bispecific antibodies (bsAbs) composed of two regular Fab arms fused via flexible linker peptides to one asymmetric third Fab-sized binding module. This third module replaces the IgG Fc region and is composed of the variable re...

  • Case Report
  • Open Access
1 Citations
2,522 Views
17 Pages

Flow Cytometry Analysis in Breast Implant-Associated Anaplastic Large Cell Lymphoma: Three Case Reports

  • Veronica Davanzo,
  • Alessandra Falda,
  • Paola Fogar,
  • Kathrin Ludwig,
  • Jenny Zuin,
  • Maria Cristina Toffanin,
  • Marco Pizzi,
  • Angelo Paolo Dei Tos and
  • Daniela Basso

Breast Implant-Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL) is a rare T-cell non-Hodgkin lymphoma associated with breast prosthetic implants and represents a diagnostic challenge. The National Comprehensive Cancer Network (NCCN) guidelines, u...

  • Article
  • Open Access
12 Citations
3,318 Views
16 Pages

Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex

  • Stefano D’Errico,
  • Andrea Patrizia Falanga,
  • Domenica Capasso,
  • Sonia Di Gaetano,
  • Maria Marzano,
  • Monica Terracciano,
  • Giovanni Nicola Roviello,
  • Gennaro Piccialli,
  • Giorgia Oliviero and
  • Nicola Borbone

Herein, we reported on the synthesis of a novel Pt(II) neutral complex having as ligand the nucleoside tubercidin, a potent anti-tumor agent extracted from the bacterium Streptomyces Tubercidicus. In detail, the chelation of the metal by a diamine li...

  • Article
  • Open Access
4 Citations
3,681 Views
22 Pages

Pathogenic D76N Variant of β2-Microglobulin: Synergy of Diverse Effects in Both the Native and Amyloid States

  • Éva Bulyáki,
  • Judit Kun,
  • Tamás Molnár,
  • Alexandra Papp,
  • András Micsonai,
  • Henrietta Vadászi,
  • Borbála Márialigeti,
  • Attila István Kovács,
  • Gabriella Gellén and
  • Keiichi Yamaguchi
  • + 8 authors

17 November 2021

β2-microglobulin (β2m), the light chain of the MHC-I complex, is associated with dialysis-related amyloidosis (DRA). Recently, a hereditary systemic amyloidosis was discovered, caused by a naturally occurring D76N β2m variant, which showed a structur...

  • Article
  • Open Access
7 Citations
7,278 Views
13 Pages

21 February 2014

Telomeric DNA has been intensely investigated for its role in chromosome protection, aging, cell death, and disease. In humans the telomeric tandem repeat (TTAGGG)n is found at the ends of chromosomes and provides a novel target for the development o...

  • Article
  • Open Access
36 Citations
9,781 Views
18 Pages

Improvement of Thermal Stability via Outer-Loop Ion Pair Interaction of Mutated T1 Lipase from Geobacillus zalihae Strain T1

  • Rudzanna Ruslan,
  • Raja Noor Zaliha Raja Abd. Rahman,
  • Thean Chor Leow,
  • Mohd Shukuri Mohamad Ali,
  • Mahiran Basri and
  • Abu Bakar Salleh

17 January 2012

Mutant D311E and K344R were constructed using site-directed mutagenesis to introduce an additional ion pair at the inter-loop and the intra-loop, respectively, to determine the effect of ion pairs on the stability of T1 lipase isolated from Geobacill...

  • Article
  • Open Access
3 Citations
2,190 Views
10 Pages

Ring and Linear Structures of CdTe Clusters

  • Andrii Kashuba,
  • Ihor Semkiv,
  • Myron Rudysh,
  • Hryhorii Ilchuk and
  • Pavlo Shchepanskyi

30 June 2024

We report the results of an ab initio study of the linear and ring structures of cadmium telluride clusters [CdTe]n (CdnTen) n ≤ 10 within the generalized gradient approximation (GGA) and Purdue–Burke–Ernzerhof (PBE) parameterization w...

  • Article
  • Open Access
3 Citations
3,737 Views
14 Pages

I-Motif is a tetrameric cytosine-rich DNA structure with hemi-protonated cytosine: cytosine base pairs. Recent evidence showed that i-motif structures in human cells play regulatory roles in the genome. Therefore, characterization of novel i-motifs a...

  • Article
  • Open Access
12 Citations
4,916 Views
13 Pages

KRAS Promoter G-Quadruplexes from Sequences of Different Length: A Physicochemical Study

  • Federica D’Aria,
  • Bruno Pagano,
  • Luigi Petraccone and
  • Concetta Giancola

DNA G-quadruplexes (G4s) form in relevant genomic regions and intervene in several biological processes, including the modulation of oncogenes expression, and are potential anticancer drug targets. The human KRAS proto-oncogene promoter region contai...

  • Protocol
  • Open Access
10 Citations
5,518 Views
14 Pages

Purification and Characterization of Recombinant Expressed Apple Allergen Mal d 1

  • Julia A. H. Kaeswurm,
  • Bettina Nestl,
  • Sven M. Richter,
  • Max Emperle and
  • Maria Buchweitz

27 December 2020

Mal d 1 is the primary apple allergen in northern Europe. To explain the differences in the allergenicity of apple varieties, it is essential to study its properties and interaction with other phytochemicals, which might modulate the allergenic poten...

  • Article
  • Open Access
38 Citations
5,734 Views
31 Pages

27 January 2021

Active targeting and overcoming multi-drug resistance (MDR) can be some of the important attributes of targeted therapy for metastatic breast cancer (MBC) and triple-negative breast cancer (TNBC) treatment. In this study, we constructed a hyaluronic...

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