- Article
Development, Characterization and Cell Viability Inhibition of PVA Spheres Loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for Osteosarcoma
- Viviane Seba,
- Gabriel Goetten de Lima,
- Bruno L. Pereira,
- Gabriel Silva,
- Luiza Steffens Reinhardt,
- Pablo Ricardo Arantes,
- Bor Shin Chee,
- Mariana Bastos dos Santos,
- Suzelei C. França and
- Mozart Marins
- + 3 authors
Chalcones (1,3-diaryl-2-propen-1-ones) are naturally occurring polyphenols with known anticancer activity against a variety of tumor cell lines, including osteosarcoma (OS). In this paper, we present the preparation and characterization of spheres (~...