Announcements
28 January 2026
Viruses | Issue Cover Papers in the Second Half of 2025
by Jenna M. Hasson, Mary Grace Katusiime, Adam A. Capoferri, Michael J. Bale, Brian T. Luke, Wei Shao, Mark F. Cotton, Gert van Zyl, Sean C. Patro and Mary F. Kearney
Viruses 2025, 17(7), 961; https://doi.org/10.3390/v17070961
Available online: https://www.mdpi.com/1999-4915/17/7/961
by Kazuaki Mawatari, Yasuko Kadomura-Ishikawa, Takahiro Emoto, Yushi Onoda, Kai Ishida, Sae Toda, Takashi Uebanso, Toshihiko Aizawa, Shigeharu Yamauchi, Yasuo Fujikawa et al.
Viruses 2025, 17(8), 1065; https://doi.org/10.3390/v17081065
Available online: https://www.mdpi.com/1999-4915/17/8/1065
by Aamir Lal, Muhammad Amir Qureshi, Man-Cheol Son, Sukchan Lee and Eui-Joon Kil
Viruses 2025, 17(9), 1213; https://doi.org/10.3390/v17091213
Available online: https://www.mdpi.com/1999-4915/17/9/1213
by Alessio Noghero, Stephanie Byrum, Chioma Okeoma and Adriana E. Kajon
Viruses 2025, 17(10), 1300; https://doi.org/10.3390/v17101300
Available online: https://www.mdpi.com/1999-4915/17/10/1300
by Somnath Mondal, Saumyak Mukherjee, Kevin E. W. Namitz, Neela H. Yennawar and David D. Boehr
Viruses 2025, 17(11), 1473; https://doi.org/10.3390/v17111473
Available online: https://www.mdpi.com/1999-4915/17/11/1473
by David Aponte-Diaz, Abha Jain, Jayden M. Harris, Jamie J. Arnold and Craig E. Cameron
Viruses 2025, 17(12), 1556; https://doi.org/10.3390/v17121556
Available online: https://www.mdpi.com/1999-4915/17/12/1556
28 January 2026
Viruses | Selected Papers from Editorial Board Members in 2025
1. “Multivalent Interactions Between the Picornavirus 3C(D) Main Protease and RNA Oligonucleotides Induce Liquid–Liquid Phase Separation”
by Somnath Mondal, Saumyak Mukherjee, Kevin E. W. Namitz, Neela H. Yennawar and David D. Boehr
Viruses 2025, 17(11), 1473; https://doi.org/10.3390/v17111473
Available online: https://www.mdpi.com/1999-4915/17/11/1473
2. “Small Molecule Compounds Inhibit Varicella-Zoster Virus Replication by Targeting the Portal Protein–Capsid Interface”
by Julius Svensmark, Emily Polk, Ellyn Kornfeind, Whitney Lane, Melissa A. Visalli and Robert J. Visalli
Viruses 2025, 17(11), 1496; https://doi.org/10.3390/v17111496
Available online: https://www.mdpi.com/1999-4915/17/11/1496
3. “Minimal Polymerase-Containing Precursor Required for Chikungunya Virus RNA Synthesis”
by David Aponte-Diaz, Abha Jain, Jayden M. Harris, Jamie J. Arnold and Craig E. Cameron
Viruses 2025, 17(12), 1556; https://doi.org/10.3390/v17121556
Available online: https://www.mdpi.com/1999-4915/17/12/1556
4. “Interferons Inhibit Ebola Virus Infection of Human Keratinocytes”
by Jonah Elliff, Hanora Van Ert, Kristina Sevcik, Marija Anne Djurkovic, Danielle Rudd, Francoise Gourronc, Aloysius Klingelhutz, Olena Shtanko and Wendy Maury
Viruses 2025, 17(12), 1577; https://doi.org/10.3390/v17121577
Available online: https://www.mdpi.com/1999-4915/17/12/1577
5. “Resistance Mutations to Broadly Neutralizing Antibodies Destabilize Hemagglutinin and Attenuate H1N1 Influenza Virus”
by Guohua Yang, Po-Ling Chen, Samuel W. Rovito, Karine Minari, Haley N. Writt, Jennifer DeBeauchamp, Jeri Carol Crumpton, Lisa Kercher, Rebecca M. DuBois, Richard J. Webby et al.
Viruses 2026, 18(1), 32; https://doi.org/10.3390/v18010032
Available online: https://www.mdpi.com/1999-4915/18/1/32
6. “Genome-Wide Variation Profile of the Genus Tobamovirus”
by Amany E. Gomaa and Hernan Garcia-Ruiz
Viruses 2025, 17(9), 1284; https://doi.org/10.3390/v17091284
Available online: https://www.mdpi.com/1999-4915/17/9/1284
7. “Modification of H1N1 Influenza Luciferase Reporter Viruses Using StopGo Translation and/or Mouse-Adapted Mutations”
by Po-Ling Chen, Guohua Yang, Chet Ojha, Balaji Banoth and Charles J. Russell
Viruses 2025, 17(9), 1211; https://doi.org/10.3390/v17091211
Available online: https://www.mdpi.com/1999-4915/17/9/1211
8. “Immune Responses and Replication of Rescued Torque Teno Virus (TTSuV1) in Mice”
by Md-Tariqul Islam, Brett Webb and Sheela Ramamoorthy
Viruses 2025, 17(8), 1105; https://doi.org/10.3390/v17081105
Available online: https://www.mdpi.com/1999-4915/17/8/1105
9 January 2026
MDPI’s Newly Launched Journals in December 2025
We have expanded our open access portfolio with eight new journals publishing their inaugural issues in December 2025, as well as three journal transfers. These additions span physical sciences, social sciences, arts and humanities, environmental and Earth sciences, medicine and pharmacology, and public health and healthcare. We extend our sincere thanks to the Editors-in-Chief, Associate Editors, and Editorial Board Members who are shaping these journals’ direction. All journals uphold strong editorial standards through a thorough peer review process, ensuring impactful open access scholarship.
Please feel free to browse and discover more about the new journals below.
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New Journals |
Founding Editor-in-Chief(s) |
Journal Topics (Selected) |
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Dr. Elisa Felicitas Arias, Université PSL, France |
atomic clocks; time and frequency metrology; GNSS systems; relativity and relativistic timekeeping; fundamental physics in space | |
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Prof. Dr. José F.F. Mendes, University of Aveiro, Portugal |
complex systems; network science; nonlinear dynamics and chaotic behaviour; information theory and complexity; computational complexity | |
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Prof. Dr. Roberto Morandotti, Institut National de la Recherche Scientifique—Énergie, Matériaux et Télécommunications (INRS), Canada |
light generation; light sources and applications; light control and measurement; human responses to light; lighting design | |
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Prof. Dr. Savvas A. Chatzichristofis, Neapolis University Pafos, Cyprus |
generative AI and large language models in education; multimodal and embodied AI; personalization and adaptive systems; assessment, feedback, and academic integrity; learning analytics | |
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Prof. Dr. Jon Andoni Duñabeitia, Universidad Nebrija, Spain |
cognitive psychology; cognitive neuroscience; psycholinguistics; applied linguistics; experimental psychology | |
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Prof. Dr. Caiwu Fu, Wuhan University, China; Prof. Dr. Longxi Zhang, Peking University, China |
cultural practices; cultural theory; cultural policy; cultural heritage; transregional and transnational cultural flows| |
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Dr. Ghassem R. Asrar, iCREST Environmental Education Foundation, USA |
biosphere interactions, processes, and sustainability; ecosystem science and dynamics; biodiversity conservation; global change and environmental adaptation; biogeochemical cycles | |
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Dr. Giuseppe Mulè, University of Palermo, Italy |
cardiorenal syndromes; chronic heart failure and chronic kidney disease; cardiorenalmetabolic syndrome; hypertension and diabetes in relation to the abovementioned syndromes; diagnostic techniques | |
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Transferred Journals |
Editor-in-Chief |
Journal Topics (Selected) |
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Prof. Dr. Peter Matt, Lucerne Cantonal Hospital (LUKS), Switzerland |
cardiology; cardiovascular and aortic surgery; cardiovascular anatomy, physiology and pathophysiology; congenital heart disease and pediatric cardiology; cardiovascular regenerative and reparative medicine | |
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Prof. Dr. Oana Săndulescu, Carol Davila University of Medicine and Pharmacy, Romania; National Institute for Infectious Diseases “Prof. Dr. Matei Bals”, Romania |
infectious diseases across clinical and public health domains; epidemiology of communicable diseases; clinical microbiology and applied virology; vaccinology and immunization; host–pathogen interactions and immunity | |
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Dr. Roxana Elena Bohiltea, “Carol Davila” University of Medicine and Pharmacy, Romania |
public health; disease prevention; screening and early detection; lifestyle interventions and health education; digital and innovative prevention | |
We would like to thank everyone who has supported the development of open access publishing. If you would like to create more new journals, you are welcome to send an application here, or contact the New Journal Committee (newjournal-committee@mdpi.com).
31 December 2025
MDPI INSIGHTS: The CEO's Letter #30 - Scaling with Integrity, Highly Cited Researchers, KEMÖ Consortium, Michele Parrinello, and Best PhD Thesis Awards
Welcome to the MDPI Insights: The CEO's Letter.
In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.
Opening Thoughts
With colleagues at MDPI headquarters in Basel, representing the people behind our global growth and shared commitment to integrity.
Scaling with Integrity: A Year of Growth, Responsibility, and Trust
When I look back on 2025, one phrase seems to sum up the year: “Scaling with integrity.” That was our watchword for 2025, and it will remain so as we move forward in to 2026.
Our journal portfolio continued to grow in 2025, reflecting the trust of a widening proportion of the scholarly community.
Today, MDPI has 355 journals indexed in Scopus and 330 in Web of Science – a testimonial to the scale at which our journals meet established external quality criteria. During the year, 45 of our journals were newly accepted into Scopus and 29 into Web of Science (this excludes transferred journals to our portfolio that were already indexed), following rigorous, independent evaluation by the world’s leading indexing bodies
Meeting external quality benchmarks
These results underline the fact that scaling responsibly is not only about expanding our catalogue, but also about meeting external quality benchmarks consistently, transparently, and at scale. Our indexing performance remains one of the strongest independent validations of MDPI’s commitment to rigor, trust, and long-term sustainability.
Over the course of 2025, we made targeted investments to ensure that the integrity of our editorial process scaled to keep pace with our growth. We strengthened our editorial governance by doubling down on our dedicated Publication Ethics department, appointing a Head of Ethics, and expanding our research integrity team by the addition of new specialists plus the creation of embedded editorial ethics roles across key journals. We also introduced new internal ethics guidelines, pre-review integrity checks, and monitoring dashboards to help teams identify potential issues and apply consistent standards across our portfolio.
Besides investing in systems and tools, we of course also invested heavily in our people and culture, delivering organisation-wide training on topics such as image integrity, AI use in publishing, and ethical oversight, while actively engaging with the wider publishing community through COPE and STM forums.
All these efforts reflect a simple principle: growth only matters if it is matched by rigor, responsibility, and trust.
Technology and AI: Supporting the editorial decision-making process
At MDPI, AI is designed to assist, not replace, editorial decision-making. It is one element in a broader system that combines people, technology, and processes to support scale responsibly.
In 2025, we continued to invest heavily in technology that supports quality rather than shortcuts. Our AI team doubled in size, ensuring that increased automation goes hand-in-hand with expertise and oversight. Proprietary AI tools such as Scholar Finder have significantly improved the precision of reviewer matching, while Ethicality has been widely adopted across editorial workflows to identify contextual signals, such as scope alignment and citation behaviour, so that human judgment can be applied where it matters most.
Partnerships: Institutional Open Access Program (IOAP) agreements and Societies
Our recent growth is also reflected in the strength of our partnerships. In 2025, we entered into more than 150 new IOAP agreements, bringing our total to 975 active agreements worldwide. This activity included the signing of our first-ever consortium agreements in North America, renewals of all major national consortia in the UK, Switzerland, Sweden, Norway, Austria, and Croatia, and the conclusion of several flat-fee agreements. At the same time, we concluded a total of 30 agreements, encompassing 24 new Society affiliations, four strategic publishing partnerships, and two journal acquisitions.
In 2025, we opened MDPI USA in Philadelphia – our latest global office, which complements our Toronto office in representing North America. MDPI USA is responsible for accelerating Open Access in the US through ongoing support of our scholars and for expanding our institutional and society partnerships.
On the other side of the globe, meanwhile, we signed an IOAP agreement in India, allowing researchers discounted Article Processing Charges (APCs), streamlined APC management for universities, and visibility into submissions, supporting India’s push for wider Open Access by offering flexible models and helping institutions meet national mandates such as Plan S.
Sustainability, sponsorships and awards
We continued to expand our sustainability efforts during 2025, hosting the 11th World Sustainability Forum, awarding CHF 125,000 in sustainability-related funding, and launching the Z-Forum on Sustainability and Innovation conference, which will officially take place in January 2026.
We also saw a record year for conference sponsorships and awards (while establishing new awards such as the Michele Parrinello Award), recognising scholars across disciplines and reinforcing our commitment to supporting the global research community at every stage of the academic journey.
Deepening our relationships
In 2025, I had the opportunity to travel more widely than ever before on MDPI business, meeting many of our stakeholders face to face and relishing the opportunity to gain a deeper understanding of their science communication needs. It was also excellent to visit a large number of MDPI offices and witness the commitment and service orientation of so many of our colleagues around the world. I shall resume my itinerary in the new year, and I look forward to many more such interactions.
Looking ahead to 2026, we will be celebrating a very significant milestone: 30 years of MDPI. From our foundation as a single Open Access journal in 1996 to the global publishing organisation we are today, our mission has remained consistent: advancing Open Access through rigorous and trustworthy scientific communication.
I would like to take this opportunity to thank all our stakeholders – authors, Editors-in-Chief, Editorial Board members, and reviewers – who have placed their trust in us during 2025. On behalf of the entire MDPI team, I look forward to deepening our relationships yet further in 2026 and celebrating 30 Years of Open Science at MDPI, something we’ve built together.
Basel, Switzerland, where MDPI was founded in 1996.
Impactful Research
621 MDPI Editors Named Highly Cited Researchers in 2025
I am pleased to share an important milestone for our editorial community and for MDPI. In late November, Clarivate announced the 2025 Highly Cited Researchers, and 621 MDPI Editorial Board Members were included among the most influential scientific contributors over the past decade!
The 621 editors come from 33 countries, representing 21 scientific disciplines, and account for nearly one in every ten Highly Cited Researchers globally. This recognition speaks to the depth of expertise across our Editorial Boards and the strength of the scientific communities that choose to collaborate with MDPI. It is important to note that while citation metrics are not in themselves a proxy for quality, they do offer one lens on sustained scientific influence.
“Our strength comes from the scientific communities who choose to work with us”
Why this is important
Having more than 600 editors recognized on this list highlights:
- The high level of expertise guiding peer review across our journals
- The global and disciplinary diversity within our Editorial Boards
- Our commitment to maintaining strong, knowledgeable, and engaged editorial oversight
Impactful science is of course shaped by broad, diverse research communities, and no single metric captures the full picture of research quality. However, this recognition does serve as meaningful, independent affirmation of the calibre of many editors who contribute to MDPI’s work.
A closer look at the recognition
Clarivate’s methodology highlights researchers whose publications rank in the top one per cent by citation count, reflecting consistent influence over the past decade. The process includes:
- Evaluation of c. 200,000 highly cited papers
- Removal of retracted publications
- Filtering of papers with unusually large authorship groups to focus on clear contributions
That so many of our editors meet these thresholds reflects the impact of the communities behind our journals.
What this means going forward
This recognition underlines the fact that our strength comes from the scientific communities who choose to work with us.
For authors, partners, and readers, it confirms that:
- MDPI journals benefit from editorial guidance grounded in active, high-impact research
- Our Editorial boards include leaders who are helping shape the future direction of their fields
- MDPI continues to attract experts who value openness, efficiency, and scientific integrity
For our internal teams, it is a reminder that the work we do every day (supporting editors, refining workflows, and improving systems) directly contributes to the trust placed in MDPI by researchers worldwide.
Thank you to all our editorial teams, publishing staff, and journal relationship specialists, and to everyone who collaborates with our Editorial Boards. Achievements like this are only possible because of your ongoing hard work, dedication, and collaboration.
From our first annual MDPI UK Summit in Manchester, bringing together over 30 Chief Editors and Editorial Board Members to discuss MDPI’s mission, achievements, and collaborations in the UK.
Inside MDPI
MDPI Launches the Michele Parrinello Award for Computational Physical Science
In case you missed it, in November, we announced the launch of the Michele Parrinello Award. This new biennial international award will recognize pioneering contributions in computational physical science. The award honours Michele Parrinello, one of the most influential scientists of the past half-century in atomistic simulations and computational materials research.
This award reflects MDPI’s long-standing commitment to recognizing scientific excellence, supporting foundational research, and inspiring the next generation of scholars across disciplines.
“Be confident that what you do is meaningful”
Honouring a transformative scientific legacy
Professor Parrinello’s work has fundamentally reshaped how scientists model matter at the atomic scale. Together with Roberto Car, he introduced ab initio molecular dynamics, widely known as the Car–Parrinello method, opening new pathways in electronic structure calculations and molecular simulations. His subsequent contributions, including the Parrinello–Rahman method and metadynamics, have become core tools across physics, chemistry, materials science, and increasingly biology.
“Do not be afraid of new things. I see it many times when we discuss a new thing that young people are scared to go against the mainstream a little bit, thinking, ‘What is going to happen to me?’ and so on. Be confident that what you do is meaningful, and do not be afraid, do not listen too much to what other people have to say.”
– Professor Michele Parrinello
A global, community-led award
The award committee is chaired by Xin-Gao Gong, Professor of Physics at Fudan University and academician of the Chinese Academy of Sciences.
The Institute for Computational Physical Sciences at Fudan University will serve as the supporting institute, reinforcing the award’s international and cross-cultural foundation.
Nominations for the first edition of the Michele Parrinello Award opened on 1 November 2025, with submissions accepted until March 2026. The award will recognize scientists whose work has advanced computational physical science across physics, chemistry, and materials research – fields increasingly central to energy, sustainability, advanced manufacturing, and technological innovation.
Why this matters for MDPI
The Michele Parrinello Award is part of the MDPI Sustainability Foundation, which supports science as a driver of long-term societal progress.
Alongside other foundation-level honours, including the World Sustainability Award, the Emerging Sustainability Leader Award, and the Tu Youyou Award, this new prize builds on our role in supporting excellence across career stages and disciplines.
MDPI journals and programs continue to recognize researchers through Best Paper Awards, Young Investigator Awards, Travel Awards, Best PhD Thesis Awards, and Outstanding Reviewer Awards. Together, these initiatives reflect a simple belief: strong scientific communities are built through recognition, trust, and sustained support.
As MDPI approaches its 30th anniversary, the launch of the Michele Parrinello Award highlights our commitment not only to publishing research but also to helping shape the future of science by celebrating those who expand its boundaries.
Coming Together for Science
KEMÖ Consortium (Austria) Extends Open Access Agreement with MDPI until 2027
I’m pleased to share that MDPI has renewed its Institutional Open Access Program (IOAP) agreement with the Austrian library consortium KEMÖ, extending our partnership through 2027.
The renewed agreement now includes 23 Austrian institutions, with the Medical University of Vienna and the University of Natural Resources and Life Sciences (BOKU) joining the partnership. Participating institutions benefit from APC discounts across MDPI’s more than 495 journals, with centralized funding options further reducing the administrative burden for researchers and libraries.
“This renewal reflects shared commitment to advancing Open Access publishing in Europe”
Austria continues to be an important and engaged research community for MDPI, with 525+ Austrian Editorial Board Members, eight Editors-in-Chief, and 15 Section Editors-in-Chief contributing to our journals.
This renewal reflects long-term trust and shared commitment to advancing Open Access publishing in Europe, and improves MDPI’s collaboration with national OA infrastructures such as the Open Access Monitor Austria. Such long-term agreements show how MDPI’s growth is increasingly built on institutional trust, collaboration, and shared commitment to Open Access.
A big thank-you to the IOAP team and everyone involved in supporting this partnership.
Closing Thoughts
Celebrating the Next Generation of Scholars: MDPI’s 2024 Best PhD Thesis Awards
One of the privileges of working in scholarly publishing is supporting the beginning of new scientific journeys. We recently announced the recipients of MDPI’s 2024 Best PhD Thesis Awards, recognizing some of the most promising emerging researchers across disciplines.
These awards do more than celebrate academic excellence. They reflect something deeper about our mission: supporting the next generation of authors and the future of Open Science.
Recognition of Excellence
This year, we made awards to 55 early-career researchers across seven fields:
- Biology and Life Sciences
- Chemistry and Materials Science
- Computer Science and Mathematics
- Engineering
- Environmental and Earth Sciences
- Medicine and Pharmacology
- Interdisciplinary ‘Other’ fields
For those of you who have completed a PhD, you’ll know first-hand that behind each number is a story of perseverance, curiosity, and sustained effort. These researchers represent institutions around the world, with thesis topics spanning:
- Brain–machine interfaces and neural engineering
- Sustainable materials and next-generation batteries
- Cancer genomics, tumour microenvironments, and immunotherapy
- AI-driven image analysis, robotics, and computational models
- Climate change monitoring and environmental risk assessment
- Regenerative medicine, biomaterials, and drug development
These dissertations are early signs of the scientific directions that will shape the coming decade.
“Our mission is about building a global community of authors”
Why this is important
Every year, millions of scholars begin their research careers with limited visibility and few platforms for sharing their work. By recognizing outstanding PhD theses, we elevate authors early in their academic journeys, build MDPI’s connection to the global research community, reinforce our commitment to quality and rigor, and highlight the depth and breadth of scholarship published across our portfolio (from biology to materials science to mathematics).
A foretaste of the future
These 55 awardees represent the next generation of researchers whose work will influence science, policy, and society in the years ahead. What we support today helps shape the scientific ecosystem of tomorrow. Our mission goes beyond publishing papers. It is about building a global community of authors who will define the next era of scientific discovery.
To explore more about MDPI Awards, including current and upcoming Best PhD Thesis Awards, please click here.
Thank you to the editors, reviewers, and teams across MDPI who make these awards possible each year.
Everything we achieved this year was made possible by the collective effort of our global teams and the trust placed in us by the scholarly community. Thank you again, and here’s to the successful continuation of our collaboration in 2026!
Chief Executive Officer
MDPI AG
31 December 2025
Viruses | Selected Papers on Antiviral Strategies and Drug Resistance
1. “Prevalence of Emergent Dolutegravir Resistance Mutations in People Living with HIV: A Rapid Scoping Review”
by Carolyn Chu, Kaiming Tao, Vinie Kouamou, Ava Avalos, Jake Scott, Philip M. Grant, Soo-Yon Rhee, Suzanne M. McCluskey, Michael R. Jordan, Rebecca L. Morgan et al.
Viruses 2024, 16(3), 399; https://doi.org/10.3390/v16030399
Available online: https://www.mdpi.com/1999-4915/16/3/399
2. “Recent Advances on Targeting Proteases for Antiviral Development”
by Pedro Henrique Oliveira Borges, Sabrina Baptista Ferreira and Floriano Paes Silva
Viruses 2024, 16(3), 366; https://doi.org/10.3390/v16030366
Available online: https://www.mdpi.com/1999-4915/16/3/366
3. “Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance”
by Haydar Witwit, Beatrice Cubitt, Roaa Khafaji, Esteban M. Castro, Miguel Goicoechea, Maria M. Lorenzo, Rafael Blasco, Luis Martinez-Sobrido and Juan C. de la Torre
Viruses 2025, 17(1), 92; https://doi.org/10.3390/v17010092
Available online: https://www.mdpi.com/1999-4915/17/1/92
4. “Combinations of Bacteriophage Are Efficacious against Multidrug-Resistant Pseudomonas aeruginosa and Enhance Sensitivity to Carbapenem Antibiotics”
by Christopher J. Kovacs, Erika M. Rapp, William R. Rankin, Sophia M. McKenzie, Brianna K. Brasko, Katherine E. Hebert, Beth A. Bachert, Andrew R. Kick, F. John Burpo and Jason C. Barnhill
Viruses 2024, 16(7), 1000; https://doi.org/10.3390/v16071000
Available online: https://www.mdpi.com/1999-4915/16/7/1000
5. “Nirmatrelvir Resistance in an Immunocompromised Patient with Persistent Coronavirus Disease 2019”
by Chie Yamamoto, Masashi Taniguchi, Keitaro Furukawa, Toru Inaba, Yui Niiyama, Daisuke Ide, Shinsuke Mizutani, Junya Kuroda, Yoko Tanino, Keisuke Nishioka et al.
Viruses 2024, 16(5), 718; https://doi.org/10.3390/v16050718
Available online: https://www.mdpi.com/1999-4915/16/5/718
6. “Trends in and Risk Factors for Drug Resistance in Mycobacterium tuberculosis in HIV-Infected Patients”
by Xiaoqin Le, Xueqin Qian, Li Liu, Jianjun Sun, Wei Song, Tangkai Qi, Zhenyan Wang, Yang Tang, Shuibao Xu, Junyang Yang et al.
Viruses 2024, 16(4), 627; https://doi.org/10.3390/v16040627
Available online: https://www.mdpi.com/1999-4915/16/4/627
7. “Increase of Synergistic Secondary Antiviral Mutations in the Evolution of A(H1N1)pdm09 Influenza Virus Neuraminidases”
by Susanne C. Duwe, Jeanette Milde, Alla Heider, Marianne Wedde, Brunhilde Schweiger and Ralf Dürrwald
Viruses 2024, 16(7), 1109; https://doi.org/10.3390/v16071109
Available online: https://www.mdpi.com/1999-4915/16/7/1109
8. “SARS-CoV-2 Infection and Antiviral Strategies: Advances and Limitations”
by Vinicius Cardoso Soares, Isabela Batista Gonçalves Moreira and Suelen Silva Gomes Dias
Viruses 2025, 17(8), 1064; https://doi.org/10.3390/v17081064
Available online: https://www.mdpi.com/1999-4915/17/8/1064
9. “Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal”
by Victor Pimentel, Marta Pingarilho, Cruz S. Sebastião, Mafalda Miranda, Fátima Gonçalves, Joaquim Cabanas, Inês Costa, Isabel Diogo, Sandra Fernandes, Olga Costa et al.
Viruses 2024, 16(4), 622; https://doi.org/10.3390/v16040622
Available online: https://www.mdpi.com/1999-4915/16/4/622
10. “The Synergistic Effect of Baloxavir and Neuraminidase Inhibitors against Influenza Viruses In Vitro”
by Xiaojia Guo, Lei Zhao, Wei Li, Ruiyuan Cao and Wu Zhong
Viruses 2024, 16(9), 1467; https://doi.org/10.3390/v16091467
Available online: https://www.mdpi.com/1999-4915/16/9/1467
31 December 2025
Viruses | Selected Papers on Viral Ecology and One Health
1. “Sosuga Virus Detected in Egyptian Rousette Bats (Rousettus aegyptiacus) in Sierra Leone”
by Brian R. Amman, Alusine H. Koroma, Amy J. Schuh, Immah Conteh, Tara K. Sealy, Ibrahim Foday, Jonathan Johnny, Ibrahim A. Bakarr, Shannon L. M. Whitmer, Emily A. Wright et al.
Viruses 2024, 16(4), 648; https://doi.org/10.3390/v16040648
Available online: https://www.mdpi.com/1999-4915/16/4/648
2. “Serological Evidence of Cryptic Rift Valley Fever Virus Transmission Among Humans and Livestock in Central Highlands of Kenya”
by Silvia Situma, Evans Omondi, Luke Nyakarahuka, Raymond Odinoh, Marshal Mweu, Marianne W. Mureithi, Martin M. Mulinge, Erin Clancey, Jeanette Dawa, Isaac Ngere et al.
Viruses 2024, 16(12), 1927; https://doi.org/10.3390/v16121927
Available online: https://www.mdpi.com/1999-4915/16/12/1927
3. “Perpetuation of Avian Influenza from Molt to Fall Migration in Wild Swan Geese (Anser cygnoides): An Agent-Based Modeling Approach”
by John Y. Takekawa, Chang-Yong Choi, Diann J. Prosser, Jeffery D. Sullivan, Nyambayar Batbayar and Xiangming Xiao
Viruses 2025, 17(2), 196; https://doi.org/10.3390/v17020196
Available online: https://www.mdpi.com/1999-4915/17/2/196
4. “Hantavirus Expansion Trends in Natural Host Populations in Brazil”
by José Henrique Fortes Mello, Renata L. Muylaert and Carlos Eduardo Viveiros Grelle
Viruses 2024, 16(7), 1154; https://doi.org/10.3390/v16071154
Available online: https://www.mdpi.com/1999-4915/16/7/1154
5. “Community Structure, Drivers, and Potential Functions of Different Lifestyle Viruses in Chaohu Lake”
by Yu Zheng, Zihao Gao, Shuai Wu and Aidong Ruan
Viruses 2024, 16(4), 590; https://doi.org/10.3390/v16040590
Available online: https://www.mdpi.com/1999-4915/16/4/590
6. “A Critical Review of Bovine Viral Diarrhea Virus: Spotlights on Host Plasticity and Potential Spillover Events”
by Eaftekhar Ahmed Rana, M. Asaduzzaman Prodhan, Joshua W. Aleri, Syeda Hasina Akter, Henry Annandale, Sam Abraham, Subir Sarker, Jully Gogoi-Tiwari and Jasim Muhammad Uddin
Viruses 2025, 17(9), 1221; https://doi.org/10.3390/v17091221
Available online: https://www.mdpi.com/1999-4915/17/9/1221
7. “Experimental Infection of Rats with Influenza A Viruses: Implications for Murine Rodents in Influenza A Virus Ecology”
by Long Li, Rirong Chen, Zhigang Yan, Qinglong Cai, Yi Guan and Huachen Zhu
Viruses 2025, 17(4), 495; https://doi.org/10.3390/v17040495
Available online: https://www.mdpi.com/1999-4915/17/4/495
8. “Influenza A Viruses in the Swine Population: Ecology and Geographical Distribution”
by Nailya Klivleyeva, Nurbol Saktaganov, Tatyana Glebova, Galina Lukmanova, Nuray Ongarbayeva and Richard Webby
Viruses 2024, 16(11), 1728; https://doi.org/10.3390/v16111728
Available online: https://www.mdpi.com/1999-4915/16/11/1728
9. “Epidemiology and Ecology of Toscana Virus Infection and Its Global Risk Distribution”
by Xue-Geng Hong, Mei-Qi Zhang, Fang Tang, Si-Hui Song, Jia-Yi Wang, Zhen-Yu Hu, Li-Ming Liu, Xiao-Ai Zhang, Yi Sun, Li-Qun Fang et al.
Viruses 2025, 17(1), 15; https://doi.org/10.3390/v17010015
Available online: https://www.mdpi.com/1999-4915/17/1/15
10. “Monitoring of Astroviruses, Brno-Hantaviruses, Coronaviruses, Influenza Viruses, Bornaviruses, Morbilliviruses, Lyssaviruses and Pestiviruses in Austrian Bats”
by Sasan Fereidouni, Sinan Julian Keleş, Kore Schlottau, Zoltán Bagó, Guido Reiter, Markus Milchram and Bernd Hoffmann
Viruses 2024, 16(8), 1232; https://doi.org/10.3390/v16081232
Available online: https://www.mdpi.com/1999-4915/16/8/1232
30 December 2025
Viruses | Top-Cited Papers from 2025
1. “Latin America’s Dengue Outbreak Poses a Global Health Threat”
by Michelle Teixeira de Almeida, Davi Gabriel Salustiano Merighi, Aline Biazola Visnardi, Cauê Augusto Boneto Gonçalves, Vitor Martins de Freitas Amorim, Anielle Salviano de Almeida Ferrari, Anacleto Silva de Souza and Cristiane Rodrigues Guzzo
Viruses 2025, 17(1), 57; https://doi.org/10.3390/v17010057
Available online: https://www.mdpi.com/1999-4915/17/1/57
2. “Self-Amplifying RNA: Advantages and Challenges of a Versatile Platform for Vaccine Development”
by Thomas Vallet and Marco Vignuzzi
Viruses 2025, 17(4), 566; https://doi.org/10.3390/v17040566
Available online: https://www.mdpi.com/1999-4915/17/4/566
3. “A Comprehensive Review of the Neglected and Emerging Oropouche Virus”
by Fengwei Bai, Prince M. D. Denyoh, Cassandra Urquhart, Sabin Shrestha and Donald A. Yee
Viruses 2025, 17(3), 439; https://doi.org/10.3390/v17030439
Available online: https://www.mdpi.com/1999-4915/17/3/439
4. “Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance”
by Haydar Witwit, Beatrice Cubitt, Roaa Khafaji, Esteban M. Castro, Miguel Goicoechea, Maria M. Lorenzo, Rafael Blasco, Luis Martinez-Sobrido and Juan C. de la Torre
Viruses 2025, 17(1), 92; https://doi.org/10.3390/v17010092
Available online: https://www.mdpi.com/1999-4915/17/1/92
5. “Current Dengue Virus Vaccine Developments and Future Directions”
by Govindaraj Anumanthan, Bikash Sahay and Ayalew Mergia
Viruses 2025, 17(2), 212; https://doi.org/10.3390/v17020212
Available online: https://www.mdpi.com/1999-4915/17/2/212
6. “Adeno-Associated Virus Vectors: Principles, Practices, and Prospects in Gene Therapy”
by Limor Zwi-Dantsis, Saira Mohamed, Giulia Massaro and Emad Moeendarbary
Viruses 2025, 17(2), 239; https://doi.org/10.3390/v17020239
Available online: https://www.mdpi.com/1999-4915/17/2/239
7. “Long Non-Coding RNA THRIL Promotes Influenza Virus Replication by Inhibiting the Antiviral Innate Immune Response”
by Mengying Chen, Jingyun Hu, Xinni Zhou, Ming Gao, Ning Li, Guihong Yang, Xiaojuan Chi and Song Wang
Viruses 2025, 17(2), 153; https://doi.org/10.3390/v17020153
Available online: https://www.mdpi.com/1999-4915/17/2/153
8. “Colorimetric Reverse Transcription Loop-Mediated Isothermal Amplification with Xylenol Orange Targeting Nucleocapsid Gene for Detection of Feline Coronavirus Infection”
by Kotchaporn Khumtong, Witsanu Rapichai, Wichayet Saejung, Piyamat Khamsingnok, Nianrawan Meecharoen, Siriluk Ratanabunyong, Hieu Van Dong, Supansa Tuanthap, Amonpun Rattanasrisomporn, Kiattawee Choowongkomon et al.
Viruses 2025, 17(3), 418; https://doi.org/10.3390/v17030418
Available online: https://www.mdpi.com/1999-4915/17/3/418
9. “Antagonistic Trends Between Binding Affinity and Drug-Likeness in SARS-CoV-2 Mpro Inhibitors Revealed by Machine Learning”
by Anacleto Silva de Souza, Vitor Martins de Freitas Amorim, Eduardo Pereira Soares, Robson Francisco de Souza and Cristiane Rodrigues Guzzo
Viruses 2025, 17(7), 935; https://doi.org/10.3390/v17070935
Available online: https://www.mdpi.com/1999-4915/17/7/935
10. “Transcriptional Upregulation of HERV-env Genes Under Simulated Microgravity”
by Seyedesomaye Jasemi, Elena Rita Simula, Antonella Pantaleo and Leonardo A. Sechi
Viruses 2025, 17(3), 306; https://doi.org/10.3390/v17030306
Available online: https://www.mdpi.com/1999-4915/17/3/306
30 December 2025
Viruses | Top-Read Articles from 2025
1. “Targeting Latent HIV Reservoirs: Effectiveness of Combination Therapy with HDAC and PARP Inhibitors”
by Hasset Tibebe, Dacia Marquez, Aidan McGraw, Sophia Gagliardi, Cailyn Sullivan, Grace Hillmer, Kedhar Narayan, Coco Izumi, Adleigh Keating and Taisuke Izumi
Viruses 2025, 17(3), 400; https://doi.org/10.3390/v17030400
Available online: https://www.mdpi.com/1999-4915/17/3/400
2. “Insights into Persistent SARS-CoV-2 Reservoirs in Chronic Long COVID”
by Swayam Prakash, Sweta Karan, Yassir Lekbach, Delia F. Tifrea, Cesar J. Figueroa, Jeffrey B. Ulmer, James F. Young, Greg Glenn, Daniel Gil, Trevor M. Jones et al.
Viruses 2025, 17(10), 1310; https://doi.org/10.3390/v17101310
Available online: https://www.mdpi.com/1999-4915/17/10/1310
3. “The In Situ Structure of T-Series T1 Reveals a Conserved Lambda-Like Tail Tip”
by Yuan Chen, Hao Xiao, Junquan Zhou, Zeng Peng, Yuning Peng, Jingdong Song, Jing Zheng and Hongrong Liu
Viruses 2025, 17(3), 351; https://doi.org/10.3390/v17030351
Available online: https://www.mdpi.com/1999-4915/17/3/351
4. “Phytomedical Properties of Carica papaya for Boosting Human Immunity Against Viral Infections”
by Rashmi Srivastava, Neeshma Jaiswal, Harsha Kharkwal, Neeraj Kumar Dubey and Rakesh Srivastava
Viruses 2025, 17(2), 271; https://doi.org/10.3390/v17020271
Available online: https://www.mdpi.com/1999-4915/17/2/271
5. “Molecular Dissection of Symptom Determinants in Tomato Leaf Curl New Delhi Virus in Zucchini Through Mechanical Transmission”
by Thuy T. B. Vo, Eui-Joon Kil, Marjia Tabassum, Bupi Nattanong, Muhammad Amir Qureshi, Hyo-Jin Im, Giuseppe Parrella, Taek-Kyun Lee and Sukchan Lee
Viruses 2025, 17(3), 294; https://doi.org/10.3390/v17030294
Available online: https://www.mdpi.com/1999-4915/17/3/294
6. “Medicinal Mushrooms, Probiotics and Combination of Natural Compounds in the Management of HPV: A Comparative Look at Viral Clearance and Lesion Resolution”
by Giuseppina Porcaro, Marco Calcagno and Andrea Tinelli
Viruses 2025, 17(7), 942; https://doi.org/10.3390/v17070942
Available online: https://www.mdpi.com/1999-4915/17/7/942
7. “Acute HIV-1 Infection: Paradigm and Singularity”
by Antoine Chéret
Viruses 2025, 17(3), 366; https://doi.org/10.3390/v17030366
Available online: https://www.mdpi.com/1999-4915/17/3/366
8. “Structural Virology: The Key Determinants in Development of Antiviral Therapeutics”
by Tanuj Handa, Ankita Saha, Aarthi Narayanan, Elsa Ronzier, Pravindra Kumar, Jitin Singla and Shailly Tomar
Viruses 2025, 17(3), 417; https://doi.org/10.3390/v17030417
Available online: https://www.mdpi.com/1999-4915/17/3/417
9. “La Jolla Virus: The Pathology and Transmission in Its Host Drosophila suzukii”
by Ibrahim Abdelhafiz, Tobias Kessel, Andreas Vilcinskas and Kwang-Zin Lee
Viruses 2025, 17(3), 408; https://doi.org/10.3390/v17030408
Available online: https://www.mdpi.com/1999-4915/17/3/408
10. “Impacts of Antiretroviral Therapy on the Oral Microbiome and Periodontal Health of Feline Immunodeficiency Virus-Positive Cats”
by Laura Bashor, Jennifer E. Rawlinson, Christopher P. Kozakiewicz, Elisa Behzadi, Craig Miller, Jeffrey Kim, Megan Cierzan, Mary Nehring, Scott Carver, Zaid Abdo et al.
Viruses 2025, 17(2), 257; https://doi.org/10.3390/v17020257
Available online: https://www.mdpi.com/1999-4915/17/2/257
25 December 2025
International Day of Epidemic Preparedness, 27 December 2025
International Day of Epidemic Preparedness is an annual observance aimed at enhancing awareness of epidemic prevention, preparedness and response, fostering a deeper recognition of the urgency to strengthen global resilience against infectious disease outbreaks, while also drawing attention to the widespread health, economic and social burdens that epidemics impose—especially on vulnerable populations and under-resourced regions. This day highlights the pivotal role that collective action plays in advancing epidemic surveillance, early warning systems, vaccine and therapeutic development, and equitable access to medical supplies and care, thereby reinforcing the imperative for robust and proactive epidemic preparedness.
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Biology & Life Sciences |
Medicine & Pharmacology |
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Environmental & Earth Sciences |
“Structural Insights into the SARS-CoV-2 Spike Protein and Its Implications for Antibody Resistance”
by Yuichiro Yamamoto and Kohji Noguchi
Biomolecules 2025, 15(11), 1489; https://doi.org/10.3390/biom15111489
“HSP60 and SARS-CoV-2: Les Liaisons Dangereuses”
by Adelaide Carista, Melania Ionelia Gratie, Francesco Cappello and Stefano Burgio
Biology 2025, 14(9), 1281; https://doi.org/10.3390/biology14091281
“Impact of Obesity on Immunity to the Influenza Virus: Gut Microbiota, Mechanisms, and Novel Therapeutic Strategies”
by Xiaoyue Ji and Jing Sun
Diseases 2025, 13(8), 267; https://doi.org/10.3390/diseases13080267
“Immunological Strategies for Enhancing Viral Neutralization and Protection in Antibody-Guided Vaccine Design”
by Dimitrina Miteva, Maria Kokudeva, Latchesar Tomov, Hristiana Batselova and Tsvetelina Velikova
Biologics 2025, 5(3), 21; https://doi.org/10.3390/biologics5030021
“Manifestations of Post-COVID Syndrome in Healthcare Workers in Northeast England”
by Rachael K. Raw, Jon Rees, Deborah Wilson, Sharon Gowans, Ng Cho Ee and David Chadwick
COVID 2025, 5(6), 91; https://doi.org/10.3390/covid5060091
“Aptamer Development for SARS-CoV-2 and Omicron Variants Using the Spike Protein Receptor Binding Domain as a Potential Diagnostic Tool and Therapeutic Agent”
by Prasanna V. Shekar, Anuj Kumar, Nirmitee Mulgaonkar, Samneet Kashyap, Gourav Choudhir, Sandun Fernando and Sachin Rustgi
Biomolecules 2025, 15(6), 805; https://doi.org/10.3390/biom15060805
“The Global Burden of Multidrug-Resistant Bacteria”
by Andrea Marino, Antonino Maniaci, Mario Lentini, Salvatore Ronsivalle, Giuseppe Nunnari, Salvatore Cocuzza, Federica Maria Parisi, Bruno Cacopardo, Salvatore Lavalle and Luigi La Via
Epidemiologia 2025, 6(2), 21; https://doi.org/10.3390/epidemiologia6020021
“Intricacies of Global Tuberculosis Management—EndTB-2035 on the Fence?”
by Radha Gopalaswamy and Selvakumar Subbian
J. Respir. 2025, 5(1), 4; https://doi.org/10.3390/jor5010004
“Long COVID: General Perceptions and Challenges in Diagnosis and Management”
by Katia Ozanic, Aripuana Sakurada Aranha Watanabe, Alesandra Barbosa Ferreira Machado, Vania Lucia da Silva, Vanessa Cordeiro Dias and Claudio Galuppo Diniz
COVID 2025, 5(3), 41; https://doi.org/10.3390/covid5030041
“An Increase in Aspartate Aminotransferase Can Predict Worsening Disease Severity in Japanese Patients with COVID-19”
by Kengo Matsumoto, Tsutomu Nishida, Dai Nakamatsu, Masashi Yamamoto, Koji Fukui, Osamu Morimura, Kinya Abe, Yukiyoshi Okauchi, Hiromi Iwahashi and Masami Inada
Clin. Pract. 2024, 14(4), 1601-1614; https://doi.org/10.3390/clinpract14040129
“Arbovirus Transmission in Australia from 2002 to 2017”
by Elvina Viennet, Francesca D. Frentiu, Emilie McKenna, Flavia Torres Vasconcelos, Robert L. P. Flower and Helen M. Faddy
Biology 2024, 13(7), 524; https://doi.org/10.3390/biology13070524
“Host Innate Antiviral Response to Influenza A Virus Infection: From Viral Sensing to Antagonism and Escape”
by Wenlong An, Simran Lakhina, Jessica Leong, Kartik Rawat and Matloob Husain
Pathogens 2024, 13(7), 561; https://doi.org/10.3390/pathogens13070561
“Colchicine—The Divine Medicine against COVID-19”
by Vanyo Mitev
J. Pers. Med. 2024, 14(7), 756; https://doi.org/10.3390/jpm14070756
“Towards Improved XAI-Based Epidemiological Research into the Next Potential Pandemic”
by Hamed Khalili and Maria A. Wimmer
Life 2024, 14(7), 783; https://doi.org/10.3390/life14070783
“Antimicrobial Efficacy of a Portable UV-C-Based Coating Activation Device against Candida albicans Biofilm and SARS-CoV-2 as an Additional Feature: An In Vitro Study”
by Adityakrisna Yoshi Putra Wigianto, Megumi Watanabe, Yuki Iwawaki, Takaharu Goto, Tamaki Otsuki and Tetsuo Ichikawa
Hygiene 2024, 4(1), 93-102; https://doi.org/10.3390/hygiene4010006
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“Clinical and Epidemiological Study of Mycoses” |
“Genetics of Host–Pathogen Interactions” |
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“Microorganisms in Neglected Tropical Diseases” |
“Ecology and Evolution of Viral Pathogens: From Wildlife to Human Infections” |
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“Epidemiology of Zoonotic Virus Transmission: Pathways, Host Factors, and Public Health Strategies” |
“Advances in Coronaviruses Research: Pathogenesis, Immunity, and Antivirals” |
11 December 2025
Article Layout and Template Revised for Future Volumes
