- Review
Mechanisms Involved in the Adverse Cardiovascular Effects of Selective Cyclooxygenase-2 Inhibitors
- Oscar Jesus Leal-Ramos,
- Luis Felipe Arias-Ruiz,
- José Miguel Huerta-Velázquez,
- José Pablo Lamoreaux-Aguayo,
- Dalton Butcher,
- Asela Berenice López-Cuellar,
- Karina Iveth Orozco-Jiménez and
- Olivia Torres-Bugarín
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for managing inflammation, but they are associated with gastrointestinal and renal toxicity upon long-term use. Selective cyclooxygenase-2 (COX-2) inhibitors, or coxibs, were developed to...

