Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Long-Acting Antiretrovirals
edited by Camilla Muccini and Antonella Castagna
submission deadline 15 Jun 2025 | Viewed by 267 | Submission Open
Keywords: HIV infection; HIV prevention; long-acting; antiretroviral therapy; clinical studies
(This special issue belongs to the Section Human Virology and Viral Diseases)
Bacteriophage Lytic Proteins
edited by
submission deadline 20 Jun 2025 | 3 articles | Viewed by 5860 | Submission Open
Keywords: bacteriophage; phage lysis; holins; endolysins; spanins; mycolil esterases; antimicrobials
(This special issue belongs to the Section Bacterial Viruses)
Dengue, Zika and Yellow Fever Virus Replication
edited by
submission deadline 25 Jun 2025 | Viewed by 404 | Submission Open
Keywords: flavivirus; dengue; Zika; yellow fever; virus replication; virus entry; genome replication; host cell factors; replication structures
(This special issue belongs to the Section Invertebrate Viruses)
Canine Distemper Virus
edited by Monica G. Candela and
submission deadline 30 Jun 2025 | 9 articles | Viewed by 12922 | Submission Open
Keywords: CDV taxonomy (lineages); new hosts of CDV; CDV pathogenesis; CDV epidemiology (risk factors; distribution; and prevalence); CDV prevention/risk mitigation
(This special issue belongs to the Section Animal Viruses)
Controlling Zoonotic Viral Diseases from One Health Perspective 2025
edited by and Erika Schwarz-Collins
submission deadline 30 Jun 2025 | 4 articles | Viewed by 10586 | Submission Open
Keywords: one health; viral zoonoses; control; vaccine; surveillance; epidemiology
(This special issue belongs to the Section Animal Viruses)
Viral Sepsis: Pathogenesis, Diagnostics and Therapeutics submission deadline 30 Jun 2025 | 6 articles | Viewed by 10274 | Submission Open
Keywords: viral sepsis; HIV; HBV; HCV; EBV; HDV; HEV; CMV; HSV; HPV; influenza; RSV; COVID-19; SARS-CoV-2; other viruses; viral infection; sepsis; pathogenesis; diagnosis; therapy; biomarkers; vaccination
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Advances in Alphavirus and Flavivirus Research, 2nd Edition submission deadline 30 Jun 2025 | 9 articles | Viewed by 9889 | Submission Open
Keywords: arbovirus; alphavirus; flavivirus; Chikungunya; Mayaro; Zika; dengue; diagnostics; surveillance; vaccine; antivirals; animal models
(This special issue belongs to the Section General Virology)
Vertical Transmission of Human Papillomavirus Infections
edited by
submission deadline 30 Jun 2025 | 3 articles | Viewed by 9866 | Submission Open
(This special issue belongs to the Section Animal Viruses)
Cellular Restriction Factors against Viral Infection
edited by
submission deadline 30 Jun 2025 | 2 articles | Viewed by 9513 | Submission Open
Keywords: cellular restriction factors; antiviral proteins; viral antagonists; intrinsic immunity; interferon response; innate immunity; evolution of restriction factors; evolution of viral antagonists; viral antagonists as druggable targets
(This special issue belongs to the Section General Virology)
Immune Modulation by Human Cytomegalovirus
edited by
submission deadline 30 Jun 2025 | 6 articles | Viewed by 9097 | Submission Open
Keywords: human cytomegalovirus (CMV); molecular and cellular mechanisms; cell-intrinsic immunity; adaptive immunity; innate immunity
(This special issue belongs to the Section Human Virology and Viral Diseases)
Viral Hepatitis and Liver Diseases
edited by
submission deadline 30 Jun 2025 | 7 articles | Viewed by 8482 | Submission Open
Keywords: chronic viral infection; viral hepatitis; liver fibrosis; hepatocellular carcinoma; hepatitis B virus; hepatitis C virus; hepatitis delta virus co-infection; hepatitis E virus; flavivirus; molecular mechanisms; epidemiological investigations
(This special issue belongs to the Section Human Virology and Viral Diseases)
Coronaviruses and Influenza Viruses: Evolution, Cross-Species Transmission, and Recombination
edited by
submission deadline 30 Jun 2025 | 4 articles | Viewed by 5148 | Submission Open
Keywords: coronaviruses; influenza viruses; highly pathogenic influenza viruses; species jump; avian coronaviruses; porcine coronaviruses; vaccines; diagnostic assays; one health; virus/host interaction.
(This special issue belongs to the Section Coronaviruses)
Diversity and Coinfections of Plant or Fungal Viruses, 3rd Edition submission deadline 30 Jun 2025 | 3 articles | Viewed by 4886 | Submission Open
Keywords: diagnosis; surveillance; molecular mechanism; viroid; subviral agents; mycoviruses; biological control; pesticide resistance; antiviral defense mechanism; population genetics; recombination; gene expressions; host range
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Plant Virus Spillovers
edited by and
submission deadline 30 Jun 2025 | 3 articles | Viewed by 4789 | Submission Open
Keywords: spillover; emergence; replication; wild-plant virus; transmission; virus-cell interaction; vector
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Viruses and Eye Diseases
edited by Homayon Ghiasi and
submission deadline 30 Jun 2025 | 3 articles | Viewed by 4240 | Submission Open
Keywords: ocular health; herpesviruses; herpes simplex virus (HSV); varicella zoster virus (VZV); adenovirus; respiratory viruses; Zika virus; cytomegalovirus (CMV); virus– ocular tissue interactions
(This special issue belongs to the Section Human Virology and Viral Diseases)
Interplay Between Influenza Virus and Host Factors
edited by
submission deadline 30 Jun 2025 | 2 articles | Viewed by 3383 | Submission Open
Keywords: influenza virus; host factors; proviral host factors; antiviral host factors; host adaptation; virus entry; virus assembly; virus release; innate antiviral response; interferon-stimulated genes; post-translational protein modifications
(This special issue belongs to the Section Animal Viruses)
Zoonotic Viral Diseases: Drivers, Causes, Prevention and Cure, 2nd Edition
edited by
submission deadline 30 Jun 2025 | 4 articles | Viewed by 3272 | Submission Open
Keywords: zoonotic viral diseases; drivers of emergence; disease mechanism and pathogenesis in reservoir host and end host; prevention mitigation measures; treatment
(This special issue belongs to the Section Animal Viruses)
Molecular Virus-Insect Interactions, 2nd Edition
edited by Li-Long Pan
submission deadline 30 Jun 2025 | 3 articles | Viewed by 3220 | Submission Open
Keywords: plant virus-insect vector interactions; virus transmission; entomopathogenic virus-insect host interactions; insect-specific viruses; induction and suppression of immune responses
(This special issue belongs to the Section Invertebrate Viruses)
HIV Protease
edited by
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2436 | Submission Open
Keywords: HIV protease; antiretroviral therapy; drug resistance; inhibitor development; viral maturation; viral co-evolution; natural polymorphism
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Interferon Signaling in Viral Pathogenesis
edited by Lishan Su
submission deadline 30 Jun 2025 | 1 articles | Viewed by 764 | Submission Open
Keywords: type I  interferons; virus replication; viral pathogenesis; autoimmune diseases; inflamation-induced cancer; immunotherapy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Virological and Immunological Factors Underlying HBV Functional Cure and HBV Reactivation
edited by
submission deadline 30 Jun 2025 | Viewed by 559 | Submission Open
Keywords: HBV persistence; HBV functional cure; cccDNA; immunology of HBV; HBV reactivation; immune-escape mutations
(This special issue belongs to the Section Human Virology and Viral Diseases)
Bacteriophage Diversity, 2nd Edition
edited by Bert Ely
submission deadline 30 Jun 2025 | 1 articles | Viewed by 494 | Submission Open
Keywords: bacteriophages phage; diversity genome; evolution; new genera; phage-host interactions
(This special issue belongs to the Section Bacterial Viruses)
Viral Manipulation of Plant Stress Responses
edited by and Manuel Miras
submission deadline 30 Jun 2025 | Viewed by 487 | Submission Open
Keywords: virus– plant interactions; virus– host– vector interactions; immune responses; hormone signaling; evolutionary adaptations; crop protection; stress responses
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Epigenetic Modifications in Viral Infections, Volume II submission deadline 1 Jul 2025 | Viewed by 360 | Submission Open
Keywords: viral pathogenesis; virus– host interaction; epigenetic modifications; acetylation; methylation; proteomics; genomics
(This special issue belongs to the Section General Virology)
Glycans in Virus-Host Interactions
edited by Rahul Raman
submission deadline 15 Jul 2025 | 4 articles | Viewed by 14260 | Submission Open
Keywords: glycoeptiope; glycan receptors; viruses; antibodies; lectins
(This special issue belongs to the Section Animal Viruses)
Unraveling the Pathogenesis of Persistent Virus Infection
edited by and Mie Kobayashi-Ishihara
submission deadline 15 Jul 2025 | 6 articles | Viewed by 12150 | Submission Open
Keywords: pathophysiology; persistent virus infections; chronic diseases; latency; reactivation
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Flow Virometry: A New Tool for Studying Viruses
edited by John Yin
submission deadline 15 Jul 2025 | 5 articles | Viewed by 8630 | Submission Open
Keywords: flow virometry; virus particle detection; virus counting; virus labeling/staining; virus-like particles; scanning ion occlusion sensing
(This special issue belongs to the Section General Virology)
Arboviral Diseases in Livestock submission deadline 15 Jul 2025 | 2 articles | Viewed by 2026 | Submission Open
Keywords: arbovirus; epidemiology; diagnostics; vaccines
(This special issue belongs to the Section Animal Viruses)
Advances in Small-Molecule Viral Inhibitors
edited by Chiara Bertagnin
submission deadline 15 Jul 2025 | Viewed by 176 | Submission Open
Keywords: small-molecule inhibitors; PROTACs; antiviral compounds; drug discovery; protein– protein interaction inhibitors; enzymatic inhibitors
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Spumaretroviruses: Research and Applications
edited by , Marcelo A. Soares, and Martin Löchelt
submission deadline 30 Jul 2025 | Viewed by 630 | Submission Open
Keywords: ancient retroviruses; antivirals; complex retroviruses; endogenous elements; foamy viruses; foamy virus-host interactions; foamy virus prevalence; foamy virus vectors; immune responses; molecular biology and replication; natural infections; nonhuman primates and non-primates; restriction factors spumaretroviruses; structural biology; taxonomy; viral proteins; virus detection assays; zoonoses
(This special issue belongs to the Section Animal Viruses)
COVID-19 Complications and Co-infections
edited by Amir Sohail, and
submission deadline 31 Jul 2025 | 16 articles | Viewed by 26970 | Submission Open
Keywords: SARS-CoV-2; COVID-19; complications; co-infections; hospitalization
(This special issue belongs to the Section Coronaviruses)
Bovine Influenza
edited by Dan Wang and
submission deadline 31 Jul 2025 | 5 articles | Viewed by 16162 | Submission Open
Keywords: cattle; influenza viruses; avian influenza; replication; virulence; transmission; host adaptation; reservoir; epidemiology; one health; vaccine; immune response
(This special issue belongs to the Section Animal Viruses)
Herpesviruses and Associated Diseases
edited by
submission deadline 31 Jul 2025 | 11 articles | Viewed by 12952 | Submission Open
Keywords: human herpesviruses; animal herpesviruses; viral latency and reactivation; immune evasion strategies; herpesvirus– host interactions; herpesvirus biology and pathogenesis; herpesvirus diagnosis; environmental factors; herpesvirus-associated diseases; prevention and treatment strategies; antiviral therapies; vaccine development
(This special issue belongs to the Section Human Virology and Viral Diseases)
Saliva in the Diagnosis of Viral Diseases submission deadline 31 Jul 2025 | 6 articles | Viewed by 11590 | Submission Open
Keywords: saliva; diagnosis; pathogen detection; immunity; biomarkers
(This special issue belongs to the Section Human Virology and Viral Diseases)
The Application of Viruses to Biotechnology 3.0 submission deadline 31 Jul 2025 | 5 articles | Viewed by 10891 | Submission Open
Keywords: viral vectors; plant protection; gene therapy; virus-based vaccines; viral nanotechnology; phage display; viral gene delivery; virus-mediated gene editing; virus-like particles (VLPs)
(This special issue belongs to the Section General Virology)
Evolution and Adaptation of Avian Viruses submission deadline 31 Jul 2025 | 4 articles | Viewed by 8132 | Submission Open
Keywords: virus; poultry; evolution; genetics; diagnosis; host; epidemiology; control; vaccine
(This special issue belongs to the Section Animal Viruses)
Virus Assembly and Genome Packaging submission deadline 31 Jul 2025 | 2 articles | Viewed by 4220 | Submission Open
Keywords: viral assembly; genome packaging; viral structural proteins; host protein; viral– host interactions; antiviral therapies
(This special issue belongs to the Section General Virology)
Novel Strategies to Identify and Eliminate Latent HIV Cells submission deadline 31 Jul 2025 | 1 articles | Viewed by 3085 | Submission Open
Keywords: HIV; HIV-1 infection; antiretroviral therapy (ART); HIV single cell analysis; HIV reservoir; HIV cure  
(This special issue belongs to the Section Human Virology and Viral Diseases)
Virus-Host Protein Interactions
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 2936 | Submission Open
Keywords: protein– protein interactions; antiviral drug discovery; protein target inhibitors
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Resistance submission deadline 31 Jul 2025 | 2 articles | Viewed by 2409 | Submission Open
Keywords: antiviral drugs; resistance; mechanism; mutations; viral escape; viral adaptation; variability; combination therapy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
HIV Assembly, Release and Maturation
edited by Siddhartha Datta
submission deadline 31 Jul 2025 | 1 articles | Viewed by 2168 | Submission Open
Keywords: HIV assembly and maturation; capsid stability; inositol hexakisphosphate (IP6); genome recognition; endogenous reverse transcription; reorganization; maturation inhibitors; flexibility and dynamics
(This special issue belongs to the Section Human Virology and Viral Diseases)
SARS-CoV-2 Neutralizing Antibodies 3rd Edition
edited by Youchun Wang
submission deadline 31 Jul 2025 | 2 articles | Viewed by 2045 | Submission Open
Keywords: SARS-CoV-2; neutralizing antibodies; neutralization assays; standards; monoclonal antibodies; vaccines; viral variants
(This special issue belongs to the Section Coronaviruses)
An Update on Enterovirus Research, 2nd Edition
edited by
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1458 | Submission Open
Keywords: antivirals; enteroviruses; picornavirus; diagnostics; emerging and re-emerging diseases; viral proteins; virus replication; viral targets; virus– host interactions; vaccine development
(This special issue belongs to the Section Human Virology and Viral Diseases)
Biosecurity and Plant Viruses: A Call to Action for a Sustainable Future submission deadline 31 Jul 2025 | 1 articles | Viewed by 881 | Submission Open
Keywords: biosecurity; viral disease; sustainable agriculture; emerging plant viruses; quarantine regulations
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Cascade of Care for HIV, Hepatitis and Sexually Transmitted Infections submission deadline 31 Jul 2025 | 1 articles | Viewed by 705 | Submission Open
Keywords: HIV; AIDS; cascade; linkage; HCV; HBV; sexually transmitted infections
(This special issue belongs to the Section Human Virology and Viral Diseases)
Multiple Hosts of SARS-CoV-2, 3rd Edition
edited by and Santhamani Ramasamy
submission deadline 31 Jul 2025 | 1 articles | Viewed by 621 | Submission Open
Keywords: SARS-CoV-2; animal– human interface; animal reservoirs; One Health; pathogenicity and pathogenesis; spillover and spillback; surveillance; virus evolution and adaptation; zoonoses and reverse zoonoses
(This special issue belongs to the Section Coronaviruses)
Viral Diseases of Major Crops
edited by Zaifeng Fan and Yan Shi
submission deadline 31 Jul 2025 | Viewed by 430 | Submission Open
Keywords: viral infection; viral pathogenicity; virus movement; replication; RNA silencing suppressor; host response; host factors; molecular plant– virus– vector interactions
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Maternal to Child Transmission of HIV and the Effects on Pregnancy
edited by Marta López, and
submission deadline 31 Jul 2025 | Viewed by 422 | Submission Open
Keywords: maternal to child transmission; perinatal transmission; pregnancy outcomes; HIV in pregnancy; antiretroviral treatment; preventive strategies; adverse perinatal outcome; prematurity and low birthweight
(This special issue belongs to the Section Human Virology and Viral Diseases)
Synanthropy and Zoonotic Viral Spillover
edited by
submission deadline 31 Jul 2025 | Viewed by 391 | Submission Open
Keywords: zoonoses; synanthropic interactions; virus; emergence; spillover
(This special issue belongs to the Section Animal Viruses)
Human Adenovirus (HAdV) Infection in Children
edited by Adriana Kajon and
submission deadline 31 Jul 2025 | Viewed by 338 | Submission Open
Keywords: epidemiology; pediatric; transplant recipients; antivirals; outbreak; acute respiratory illness; gastroenteritis
(This special issue belongs to the Section Human Virology and Viral Diseases)
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