You are currently on the new version of our website. Access the old version .

1,852 Results Found

  • Article
  • Open Access
17 Citations
2,989 Views
10 Pages

5 August 2021

Corneal thickness measurement is important for assessing intraocular pressure in patients with glaucoma. This study investigated the changes in corneal epithelial thickness (CET) induced by antiglaucoma medications and explored the factors affecting...

  • Article
  • Open Access
2 Citations
2,037 Views
11 Pages

22 January 2024

Background: This study analyzed the effects of topical anti-glaucoma medications on the surgical outcomes of endoscopic dacryocystorhinostomy (EDCR) in nasolacrimal duct obstruction (NLDO). Methods: This retrospective study included patients who unde...

  • Review
  • Open Access
34 Citations
5,189 Views
17 Pages

30 July 2020

The coronavirus disease 2019 (COVID-19) represents a global concern of public health caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its clinical manifestations are characterized by a heterogeneous group of symptoms and pictur...

  • Review
  • Open Access
18 Citations
8,826 Views
25 Pages

Advanced Strategies of Drug Delivery via Oral, Topical, and Parenteral Administration Routes: Where Do Equine Medications Stand?

  • Yunmei Song,
  • Candace M. Day,
  • Franklin Afinjuomo,
  • Jin-Quan E. Tan,
  • Stephen W. Page and
  • Sanjay Garg

While the global market for veterinary products has been expanding rapidly, there is still a lack of specialist knowledge of equine pharmaceutics. In many cases, the basic structure of the gastrointestinal tract (GIT) and integumentary system of the...

  • Feature Paper
  • Review
  • Open Access
11 Citations
7,381 Views
17 Pages

Emerging Research Topics in Drone Healthcare Delivery

  • Hamish A. Campbell,
  • Vanya Bosiocic,
  • Aliesha Hvala,
  • Mark Brady,
  • Mariana A. Campbell,
  • Kade Skelton and
  • Osmar J. Luiz

12 June 2024

The application of drones to assist with healthcare delivery has grown rapidly over the last decade. This industry is supported by a growing research field, and we have undertaken a systematic review of the published literature. Web-based searches re...

  • Article
  • Open Access
28 Citations
4,614 Views
19 Pages

Mobile medicine plays a significant role in optimizing medical resource allocation, improving medical efficiency, etc. Identifying and analyzing user concern elements from active online reviews can help to improve service quality and enhance product...

  • Article
  • Open Access
4 Citations
5,547 Views
12 Pages

4 September 2019

Background: Fitness to practise (FtP) impairment (failure of a healthcare professional to demonstrate skills, knowledge, character and/or health required for their job) can compromise patient safety, the profession’s reputation, and an individu...

  • Systematic Review
  • Open Access
18 Citations
6,500 Views
26 Pages

Efficacy of Topical Treatments for the Management of Symptomatic Oral Lichen Planus: A Systematic Review

  • Giorgio Serafini,
  • Alberto De Biase,
  • Luca Lamazza,
  • Giulia Mazzucchi and
  • Marco Lollobrigida

Oral lichen planus (OLP) is a chronic mucosal inflammatory disease associated with T-cell-mediated immunological dysfunction. Symptomatic OLP is a painful condition, and complete healing is often not achieved. The aim of this systematic review was to...

  • Article
  • Open Access
479 Views
14 Pages

23 November 2025

The medical discourse entails the analysis of the modalities, which are far from unbiased, by which hypotheses and results are laid out in the dissemination of findings in scientific publications. This gives different emphases on the background, rele...

  • Article
  • Open Access
1 Citations
3,270 Views
12 Pages

Influence of Clinical and Psychosocial Factors on the Adherence to Topical Treatment in Psoriasis

  • Ana Teixeira,
  • Maribel Teixeira,
  • Rita Gaio,
  • Tiago Torres,
  • Sofia Magina,
  • Maria Alzira Pimenta Dinis,
  • José Sousa-Lobo,
  • Isabel Almeida,
  • Miguel Peixoto and
  • Vera Almeida

(1) Background: Psoriasis is a common chronic inflammatory skin disease with different manifestations, affecting the quality of life at social, emotional, and professional dimensions and requiring long-term treatment. This study aimed to investigate...

  • Article
  • Open Access
2 Citations
2,948 Views
8 Pages

Evaluation of the Efficacy Duration of Topical Therapies in Eyes with Primary Open-Angle Glaucoma

  • Michele Lanza,
  • Angelo Leone,
  • Gabriele Scognamiglio,
  • Luigi Serra,
  • Clemente Maria Iodice,
  • Paolo Melillo and
  • Francesca Simonelli

19 October 2022

Background: To investigate the efficacy interval of the topical therapies available for primary open-angle glaucoma (POAG) and the ocular and systemic features potentially associated. Methods: This retrospective study included 190 patients with POAG...

  • Systematic Review
  • Open Access
8 Citations
8,452 Views
24 Pages

Managing Ocular Surface Disease in Glaucoma Treatment: A Systematic Review

  • Özlem Evren Kemer,
  • Priya Mekala,
  • Bhoomi Dave and
  • Karanjit Singh Kooner

Ocular surface disease (OSD) is a frequent disabling challenge among patients with glaucoma who use benzalkonium chloride (BAK)-containing topical glaucoma medications for prolonged periods. In this comprehensive review, we evaluated the prevalence o...

  • Review
  • Open Access
233 Views
26 Pages

Topical antibiotics have long been used for the prevention and treatment of superficial skin and soft tissue infections; however, increasing evidence indicates that their clinical value is undermined by rising antimicrobial resistance, high rates of...

  • Article
  • Open Access
19 Citations
8,438 Views
13 Pages

Alerts in Clinical Decision Support Systems (CDSS): A Bibliometric Review and Content Analysis

  • Shuo-Chen Chien,
  • Ya-Lin Chen,
  • Chia-Hui Chien,
  • Yen-Po Chin,
  • Chang Ho Yoon,
  • Chun-You Chen,
  • Hsuan-Chia Yang and
  • Yu-Chuan (Jack) Li

A clinical decision support system (CDSS) informs or generates medical recommendations for healthcare practitioners. An alert is the most common way for a CDSS to interact with practitioners. Research about alerts in CDSS has proliferated over the pa...

  • Review
  • Open Access
663 Views
21 Pages

Substance-Based Medical Device in Wound Care: Bridging Regulatory Clarity and Therapeutic Innovation

  • Daiana Ianev,
  • Michela Mori,
  • Barbara Vigani,
  • Caterina Valentino,
  • Marco Ruggeri,
  • Giuseppina Sandri and
  • Silvia Rossi

31 December 2025

Substance-based medical devices (SBMDs) are increasingly used in wound care due to their favorable safety profile, physicochemical mechanisms of action, and therapeutic effectiveness. These products often incorporate biopolymers such as hyaluronic ac...

  • Article
  • Open Access
44 Citations
3,548 Views
21 Pages

Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management

  • Amany Belal,
  • Mohamed A. Elanany,
  • Eman Y. Santali,
  • Ahmed A. Al-Karmalawy,
  • Moustafa O. Aboelez,
  • Ali H. Amin,
  • Magda H. Abdellattif,
  • Ahmed B. M. Mehany and
  • Hazem Elkady

Keratoconus (KC) is a serious disease that can affect people of any race or nationality, although the exact etiology and pathogenic mechanism are still unknown. In this study, thirty-two FDA-approved ophthalmic drugs were exposed to virtual screening...

  • Article
  • Open Access
3 Citations
1,684 Views
9 Pages

28 December 2023

This study aims to report the disparity between the ideal and actual quantities of eyedrops prescribed to individual glaucoma patients. This retrospective observational study included 676 patients receiving treatment with antiglaucoma topical medicat...

  • Review
  • Open Access
27 Citations
7,409 Views
21 Pages

This review focuses on the improved topical treatment of various medical skin conditions by the use of drugs delivered from carriers containing phospholipid soft vesicles. Topical drug delivery has many advantages over other ways of administration, h...

  • Article
  • Open Access
3,358 Views
9 Pages

An Innovative Topical Medical Device with Hyaluronic Acid and Polypeptides in Patients with Reduced Knee Function

  • Tommaso Bonanzinga,
  • Alice Giulia De Sensi,
  • Beatrice Balzarini,
  • Gian Luca Doro,
  • Luca Bertolino,
  • Luca Forte and
  • Elizaveta Kon

A topical medical device, AI500®, constituted of a single-chain polypeptide embedded in hyaluronic acid, was tested and evaluated in patients with reduced knee function due to osteoarthritis and other knee conditions. A total of 35 participants w...

  • Review
  • Open Access
6 Citations
6,333 Views
16 Pages

Translational paediatric drug development includes the exchange between basic, clinical and population-based research to improve the health of children. This includes the assessment of treatment related risks and their management. The objectives of t...

  • Article
  • Open Access
17 Citations
5,759 Views
16 Pages

Tensor-Based Semantically-Aware Topic Clustering of Biomedical Documents

  • Georgios Drakopoulos,
  • Andreas Kanavos,
  • Ioannis Karydis,
  • Spyros Sioutas and
  • Aristidis G. Vrahatis

Biomedicine is a pillar of the collective, scientific effort of human self-discovery, as well as a major source of humanistic data codified primarily in biomedical documents. Despite their rigid structure, maintaining and updating a considerably-size...

  • Article
  • Open Access
5 Citations
3,164 Views
18 Pages

Estimation of the Overuse of Preoperative Chest X-rays According to “Choosing Wisely”, “No Hacer”, and “Essencial” Initiatives: Are They Equally Applicable and Comparable?

  • Jorge Vicente-Guijarro,
  • José Lorenzo Valencia-Martín,
  • Paloma Moreno-Nunez,
  • Pedro Ruiz-López,
  • José Joaquín Mira-Solves,
  • Jesús María Aranaz-Andrés and
  • SOBRINA Working Group

Background: Overuse reduces the efficiency of healthcare systems and compromises patient safety. Different institutions have issued recommendations on the indication of preoperative chest X-rays, but the degree of compliance with these recommendation...

  • Article
  • Open Access
12 Citations
6,940 Views
16 Pages

The Efficacy and Biopharmaceutical Properties of a Fixed-Dose Combination of Disulfiram and Benzyl Benzoate

  • Maria Lajarin-Reinares,
  • Elia Martinez-Esteve,
  • Eloy Pena-Rodríguez,
  • Mariona Cañellas-Santos,
  • Sanja Bulut,
  • Kostas Karabelas,
  • Adam Clauss,
  • Carles Nieto,
  • Mireia Mallandrich and
  • Francisco Fernandez-Campos

19 September 2022

Scabies and hair lice are parasitic diseases that affect human skin and hair, respectively. The incidence and resistances of these infections are increasing. Tenutex® (disulfiram and benzyl benzoate emulsion) is an alternative to standard insecti...

  • Review
  • Open Access
1 Citations
2,200 Views
13 Pages

Preserved Ophthalmic Anti-Allergy Medication in Cumulatively Increasing Risk Factors of Corneal Ectasia

  • Tom Paterson,
  • Serap Azizoglu,
  • Moneisha Gokhale,
  • Madeline Chambers and
  • Cenk Suphioglu

22 July 2023

The prevalence of allergies is rising every year. For those who suffer from it, ocular inflammation and irritation can be inconvenient and unpleasant. Anti-allergy eyedrops are a readily available treatment for symptoms of ocular allergy (OA) and can...

  • Brief Report
  • Open Access
5 Citations
2,240 Views
7 Pages

19 January 2024

Background: During endotracheal intubation, there is a 10% incidence of difficult laryngoscopy, which may result in serious complications. It is important to obtain as much information about the visibility of laryngeal structures before the patient i...

  • Article
  • Open Access
2 Citations
2,044 Views
11 Pages

Outcomes of Endoscopic Endonasal Dacryocystorhinostomy in Glaucoma Patients

  • Gian Marco Pace,
  • Francesco Giombi,
  • Giovanna Muci,
  • Gianmarco Giunta,
  • Francesca Pirola,
  • Egidio Serra,
  • Jessica Zuppardo,
  • Fabio Ferreli,
  • Paolo Vinciguerra and
  • Luca Malvezzi
  • + 2 authors

27 March 2024

Background: Anti-glaucoma eye drops have been investigated due to their production of fibrotic changes on the conjunctival surface, undermining the functioning of the upper lacrimal drainage system. We aimed to assess whether these effects may impair...

  • Article
  • Open Access
2,871 Views
21 Pages

Efficacy Study of Propolis Eutectic Extract in Gel Formulations for the Treatment of Bacterial Skin Diseases in Dogs

  • Dovilė Svetikienė,
  • Monika Jokubaite,
  • Gintaras Zamokas,
  • Lina Babickaite,
  • Rita Šiugždiniene and
  • Kristina Ramanauskiene

15 May 2025

Skin infections are common in veterinary practice and are often treated with topical agents. Superficial pyoderma (superficial bacterial folliculitis) is a common cause of skin disease in dogs and a reason for treatment, most caused by Staphylococcus...

  • Article
  • Open Access
1,439 Views
8 Pages

10 September 2025

Background: Topical anaesthesia of the nasal mucosa is essential for comfortable and effective nasal instrumentation. However, current methods often result in uneven anaesthesia, which can cause discomfort. This study evaluates the clinical performan...

  • Article
  • Open Access
3 Citations
3,085 Views
12 Pages

12 March 2020

In a previous work, a parsimonious topic model (PTM) was proposed for text corpora. In that work, unlike LDA, the modeling determined a subset of salient words for each topic, with topic-specific probabilities, with the rest of the words in the dicti...

  • Review
  • Open Access
52 Citations
12,609 Views
32 Pages

Making Medicines Baby Size: The Challenges in Bridging the Formulation Gap in Neonatal Medicine

  • Fiona O’Brien,
  • David Clapham,
  • Kamelia Krysiak,
  • Hannah Batchelor,
  • Peter Field,
  • Grazia Caivano,
  • Marisa Pertile,
  • Anthony Nunn and
  • Catherine Tuleu

The development of age-appropriate formulations should focus on dosage forms that can deliver variable yet accurate doses that are safe and acceptable to the child, are matched to his/her development and ability, and avoid medication errors. However,...

  • Feature Paper
  • Article
  • Open Access
5 Citations
5,392 Views
11 Pages

Design of an Emulgel for Psoriasis Focused on Patient Preferences

  • Rita Sanches Oliveira,
  • Diva Ferraz da Silva,
  • Sandra Mota,
  • Jorge Garrido,
  • Ermelinda Manuela Garrido,
  • José Manuel Sousa Lobo and
  • Isabel Filipa Almeida

23 March 2022

Adherence to topical treatments is low and is known to be influenced by the vehicle properties. Betamethasone dipropionate (BD) is an anti-inflammatory steroid, used in psoriasis treatment in the form of an ointment, cream, or solution. The aim of th...

  • Article
  • Open Access
3 Citations
2,402 Views
9 Pages

Topical Treatment of Elevated Intraocular Pressure in Patients with Graves’ Orbitopathy

  • Magdalena Gumińska,
  • Roman Goś,
  • Janusz Śmigielski and
  • Michał S. Nowak

Purpose: In this study, we evaluated the efficacy of topical hypotensive treatment and/or systemic corticosteroids therapy in patients with elevated intraocular pressure and Graves’ orbitopathy (GO). Methods: We included 172 eyes in 86 individu...

  • Review
  • Open Access
9 Citations
7,643 Views
15 Pages

Treatment Options for Troublesome Itch

  • Sumika Toyama,
  • Mitsutoshi Tominaga and
  • Kenji Takamori

19 August 2022

Itch (or pruritus) is an unpleasant sensation, inducing the desire to scratch. It is also a major and distressing symptom of many skin and systemic diseases. The involvement of histamine, which is a major itch mediator, has been extensively examined....

  • Systematic Review
  • Open Access
8 Citations
18,182 Views
23 Pages

Evaluating the Reliability of ChatGPT for Health-Related Questions: A Systematic Review

  • Mohammad Beheshti,
  • Imad Eddine Toubal,
  • Khuder Alaboud,
  • Mohammed Almalaysha,
  • Olabode B. Ogundele,
  • Hamza Turabieh,
  • Nader Abdalnabi,
  • Suzanne A. Boren,
  • Grant J. Scott and
  • Butros M. Dahu

The rapid advancement of large language models like ChatGPT has significantly impacted natural language processing, expanding its applications across various fields, including healthcare. However, there remains a significant gap in understanding the...

  • Article
  • Open Access
12 Citations
5,063 Views
11 Pages

14 February 2022

A reverse-phase high-performance liquid chromatography method was developed to determine and quantify capsaicin (trans-8-methyl-N-vanillyl-6- nonenamid), dihydrocapsaicin (8-methyl-N-vanillylnonanamide), and camphor (trimethylbicyclo[2.2.1]heptan-2-o...

  • Article
  • Open Access
7 Citations
5,047 Views
24 Pages

Menopausal Hormone Therapy, an Ever-Present Topic: A Pilot Survey about Women’s Experience and Medical Doctors’ Approach

  • Carmen Imma Aquino,
  • Viviana Stampini,
  • Elena Osella,
  • Libera Troìa,
  • Clarissa Rocca,
  • Maurizio Guida,
  • Fabrizio Faggiano,
  • Valentino Remorgida and
  • Daniela Surico

Background and Objective: Menopause can be associated with many clinical manifestations: vasomotor symptoms, urogenital problems, and additional psychological disturbances, such as anxiety, mood changes, and sleep alterations. The prolonged lack of h...

  • Article
  • Open Access
590 Views
19 Pages

Relevance of Social Medicine Skills and the Role of Teaching Formats in the Perception of Medical Students: A Retrospective Trend Study

  • Sibylle Hildenbrand,
  • Joachim Graf,
  • Martina Michaelis,
  • Anke Wagner,
  • Susanne Völter-Mahlknecht,
  • Elisabeth Simoes and
  • Monika A. Rieger

20 October 2025

During medical school, students in Germany acquire knowledge, abilities, competencies, and skills in social medicine. The aim of this study was to investigate how human medicine students perceive the relevance of selected social medical issues and th...

  • Article
  • Open Access
1 Citations
1,936 Views
12 Pages

Antimicrobial Prescribing Preparedness of Croatian Medical Students—Did It Change between 2015 and 2019?

  • Dora Palčevski,
  • Andrej Belančić,
  • Ivan Mikuličić,
  • Eduard Oštarijaš,
  • Robert Likić,
  • Oliver Dyar and
  • Vera Vlahović-Palčevski

Background: Antimicrobials are some of the most prescribed drugs by junior doctors, but studies suggest most medical graduates feel unprepared for their future prescribing tasks. The aim of the present study was to compare the self-reported preparedn...

  • Article
  • Open Access
2 Citations
3,762 Views
15 Pages

24 September 2024

Background/Objectives: This study aimed to identify the main issues related to public patient safety campaigns reflected in Korean online news. This study utilized a text-mining method to identify keywords and topics related to patient safety campaig...

  • Article
  • Open Access
6 Citations
3,537 Views
11 Pages

Medical curricula need to prepare doctors for emerging health issues and increased public health roles. With medical schools spread over a vast geographical region of Indonesia, ensuring that all schools meet appropriate standards in the quality of s...

  • Article
  • Open Access
6 Citations
3,857 Views
12 Pages

Medical Students and Childhood Obesity: Health Disparity and Implication for Education

  • Shinduk Lee,
  • Matthew Lee Smith,
  • Laura Kromann and
  • Marcia G. Ory

This study aimed at examining the relationship between medical students’ perceptions about health disparity and childhood obesity care. A cross-sectional survey (n = 163) was used to examine medical students’ characteristics and perceptio...

  • Article
  • Open Access
2 Citations
2,865 Views
14 Pages

Therapeutic Effect of Liquiritin Carbomer Gel on Topical Glucocorticoid-Induced Skin Inflammation in Mice

  • Yun Zhang,
  • Sijia Li,
  • Yanfang Huang,
  • Congjing Song,
  • Weiqiang Chen and
  • Yiling Yang

Glucocorticoids are often used and highly effective anti-inflammatory medications, but prolonged topical application may alter the epidermis’ normal structure and function, potentially resulting in a number of adverse effects. Topical glucocort...

  • Article
  • Open Access
1,805 Views
13 Pages

2015 versus 2021: Self-Reported Preparedness to Prescribe Antibiotics Prudently among Final Year Medical Students in Sweden

  • Jasmine Al-Nasir,
  • Andrej Belančić,
  • Dora Palčevski,
  • Oliver J. Dyar and
  • on behalf of Student-PREPARE Sweden Working Group

Cross-sectional surveys have found variations in how prepared medical students feel to prescribe antibiotics responsibly, but insights are lacking on the stability of these outcomes. In a 2015 survey, final-year Swedish medical students reported very...

  • Review
  • Open Access
12 Citations
3,756 Views
32 Pages

30 March 2024

The Internet of Things (IoT) is still a relatively new field of research, and its potential to be used in the healthcare and medical sectors is enormous. In the last five years, IoT has been a go-to option for various applications such as using senso...

  • Article
  • Open Access
15 Citations
4,482 Views
15 Pages

26 November 2021

With the outbreak of COVID-19 that has prompted an increased focus on self-care, more and more people hope to obtain disease knowledge from the Internet. In response to this demand, medical question answering and question generation tasks have become...

  • Article
  • Open Access
2 Citations
8,414 Views
20 Pages

Health Use Cases of AI Chatbots: Identification and Analysis of ChatGPT Prompts in Social Media Discourses

  • Amir Karami,
  • Zhilei Qiao,
  • Xiaoni Zhang,
  • Hadi Kharrazi,
  • Parisa Bozorgi and
  • Ali Bozorgi

The popularity of ChatGPT has raised questions surrounding AI’s potential for health use cases. Since the release of ChatGPT in 2022, social media users have shared their prompts and ChatGPT responses on different topics such as health. Despite...

  • Review
  • Open Access
43 Citations
21,656 Views
8 Pages

1 September 2021

Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus...

  • Article
  • Open Access
1,341 Views
10 Pages

Variation in Quality of Women’s Health Topic Information from Systematic Internet Searches

  • Bianca Kyrie Wanamaker,
  • Ashley N. Tomlinson,
  • Alivia R. Abernathy,
  • Vanessa Cordova,
  • Anika D. Baloun and
  • Benjamin D. Duval

8 October 2025

Background/Objectives: The internet has unquestionably altered how people acquire health information. Instead of consulting with a medical professional, billions of pages of information can be accessed by anyone with a smartphone. Women’s healt...

  • Review
  • Open Access
394 Citations
39,817 Views
19 Pages

Survey of Explainable AI Techniques in Healthcare

  • Ahmad Chaddad,
  • Jihao Peng,
  • Jian Xu and
  • Ahmed Bouridane

5 January 2023

Artificial intelligence (AI) with deep learning models has been widely applied in numerous domains, including medical imaging and healthcare tasks. In the medical field, any judgment or decision is fraught with risk. A doctor will carefully judge whe...

of 38