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292 Results Found

  • Review
  • Open Access
14 Citations
11,829 Views
19 Pages

Optical and Electric Multifunctional CMOS Image Sensors for On-Chip Biosensing Applications

  • Takashi Tokuda,
  • Toshihiko Noda,
  • Kiyotaka Sasagawa and
  • Jun Ohta

29 December 2010

In this review, the concept, design, performance, and a functional demonstration of multifunctional complementary metal-oxide-semiconductor (CMOS) image sensors dedicated to on-chip biosensing applications are described. We developed a sensor archite...

  • Article
  • Open Access
7 Citations
2,538 Views
17 Pages

14 September 2021

The on-chip integration of multiple biochemical sensors based on field-effect electrolyte-insulator-semiconductor capacitors (EISCAP) is challenging due to technological difficulties in realization of electrically isolated EISCAPs on the same Si chip...

  • Article
  • Open Access
5 Citations
6,837 Views
13 Pages

13 January 2019

This paper proposes a CMOS front-end readout-integrated circuit (ROIC) with on-chip non-uniformity compensation technique for a diode-based uncooled infrared image sensor. Two techniques are adopted to achieve on-chip non-uniformity compensation: a r...

  • Review
  • Open Access
59 Citations
12,215 Views
24 Pages

Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism

  • Mostafa Azimzadeh,
  • Patricia Khashayar,
  • Meitham Amereh,
  • Nishat Tasnim,
  • Mina Hoorfar and
  • Mohsen Akbari

22 December 2021

Oxygen (O2) quantification is essential for assessing cell metabolism, and its consumption in cell culture is an important indicator of cell viability. Recent advances in microfluidics have made O2 sensing a crucial feature for organ-on-chip (OOC) de...

  • Article
  • Open Access
47 Citations
13,751 Views
14 Pages

Obstacle Recognition Based on Machine Learning for On-Chip LiDAR Sensors in a Cyber-Physical System

  • Fernando Castaño,
  • Gerardo Beruvides,
  • Rodolfo E. Haber and
  • Antonio Artuñedo

14 September 2017

Collision avoidance is an important feature in advanced driver-assistance systems, aimed at providing correct, timely and reliable warnings before an imminent collision (with objects, vehicles, pedestrians, etc.). The obstacle recognition library is...

  • Article
  • Open Access
5 Citations
3,985 Views
11 Pages

15 July 2019

A novel on-chip integration of pressure plus 2-axis (X/Z) acceleration composite sensors for upgraded production of automobile tire pressure monitoring system (TPMS) is proposed, developed, and characterized. Herein, the X-axis accelerometer is with...

  • Data Descriptor
  • Open Access
3 Citations
2,476 Views
16 Pages

28 April 2024

Legitimate identification of devices is crucial to ensure the security of present and future IoT ecosystems. In this regard, AI-based systems that exploit intrinsic hardware variations have gained notable relevance. Within this context, on-chip senso...

  • Review
  • Open Access
59 Citations
16,081 Views
29 Pages

Various On-Chip Sensors with Microfluidics for Biological Applications

  • Hun Lee,
  • Linfeng Xu,
  • Domin Koh,
  • Nikhila Nyayapathi and
  • Kwang W. Oh

12 September 2014

In this paper, we review recent advances in on-chip sensors integrated with microfluidics for biological applications. Since the 1990s, much research has concentrated on developing a sensing system using optical phenomena such as surface plasmon reso...

  • Article
  • Open Access
51 Citations
4,002 Views
14 Pages

Tuning Multiple Fano Resonances for On-Chip Sensors in a Plasmonic System

  • Shilin Yu,
  • Tonggang Zhao,
  • Jianguo Yu and
  • Dafa Pan

31 March 2019

This paper proposed a plasmonic resonator system, consisting of a metal-insulator-metal structure and two stubs, and a Fano resonance arose in its transmittance, which resulted from the coupling between the two stubs. On the basis of the proposed str...

  • Communication
  • Open Access
17 Citations
5,263 Views
10 Pages

25 June 2021

This paper presents an optoelectronic receiver (Rx) IC with an on-chip avalanche photodiode (APD) realized in a 0.18-μm CMOS process for the applications of home-monitoring light detection and ranging (LiDAR) sensors, where the on-chip CMOS P+/N-well...

  • Article
  • Open Access
6 Citations
5,697 Views
11 Pages

7 March 2018

To improve the reference potential stability of on-chip amperometric sensors, we propose a novel integrated Ag/AgCl reference electrode structure. This structure can refresh the saturated potassium chloride filling solution surrounding the Ag/AgCl el...

  • Article
  • Open Access
16 Citations
11,133 Views
20 Pages

A CMOS Smart Temperature and Humidity Sensor with Combined Readout

  • Clemens Eder,
  • Virgilio Valente,
  • Nick Donaldson and
  • Andreas Demosthenous

16 September 2014

A fully-integrated complementary metal-oxide semiconductor (CMOS) sensor for combined temperature and humidity measurements is presented. The main purpose of the device is to monitor the hermeticity of micro-packages for implanted integrated circuits...

  • Article
  • Open Access
4 Citations
2,401 Views
18 Pages

Accurate On-Chip Thermal Peak Detection Based on Heuristic Algorithms and Embedded Temperature Sensors

  • Djallel Eddine Touati,
  • Aziz Oukaira,
  • Ahmad Hassan,
  • Mohamed Ali,
  • Ahmed Lakhssassi and
  • Yvon Savaria

The reliability and lifetime of systems-on-chip (SoCs) are being seriously threatened by thermal issues. In modern SoCs, dynamic thermal management (DTM) uses the thermal data captured by thermal sensors to constantly track the hot spots and thermal...

  • Communication
  • Open Access
35 Citations
6,936 Views
9 Pages

Graphene-Based Sensing Platform for On-Chip Ochratoxin A Detection

  • Nikita Nekrasov,
  • Dmitry Kireev,
  • Aleksei Emelianov and
  • Ivan Bobrinetskiy

20 September 2019

In this work, we report an on-chip aptasensor for ochratoxin A (OTA) toxin detection that is based on a graphene field-effect transistor (GFET). Graphene-based devices are fabricated via large-scale technology, allowing for upscaling the sensor fabri...

  • Article
  • Open Access
8 Citations
2,474 Views
17 Pages

10 February 2023

A refractive index sensor based on an on-chip silicon nitride (Si3N4) ridge waveguide long-range surface plasmon polariton (LRSPP) is theoretically designed. The waveguide sensor consists of a gold film to enable the plasmonic resonance on top of a C...

  • Article
  • Open Access
24 Citations
4,366 Views
11 Pages

24 March 2019

Optical whispering-gallery-mode (WGM) microresonator-based sensors with high sensitivity and low detection limit down to single unlabeled biomolecules show high potential for disease diagnosis and clinical application. However, most WGM microresonato...

  • Article
  • Open Access
34 Citations
9,644 Views
13 Pages

31 March 2017

In recent years, efforts in the development of lab-on-a-chip (LoC) devices for point-of-care (PoC) applications have increased to bring affordable, portable, and sensitive diagnostics to the patients’ bedside. To reach this goal, research has shifted...

  • Article
  • Open Access
1 Citations
4,721 Views
12 Pages

14 October 2016

This paper presents an all-digital low-power oscillator for reference clocks in wireless body area network (WBAN) applications. The proposed on-chip complementary metal-oxide-semiconductor (CMOS) oscillator provides low-frequency clock signals with l...

  • Article
  • Open Access
490 Views
11 Pages

Integrated Quasi-Optical Terahertz Liquid Sensor Leveraging Mode-Parity-Dependent Interaction with a Capillary-Confined Analyte

  • Andreas K. Klein,
  • Julian Webber,
  • Guillermo Carpintero,
  • Masayuki Fujita and
  • Daniel Headland

17 November 2025

The integration of terahertz (THz) sensing technology into compact, on-chip platforms is essential to the advancement of high-precision chemical and biomedical analysis, promising to bring analytics closer to the point of care and to enable in situ a...

  • Article
  • Open Access
24 Citations
8,030 Views
18 Pages

A CMOS Low Pass Filter for SoC Lock-in-Based Measurement Devices

  • Jorge Pérez-Bailón,
  • Belén Calvo and
  • Nicolás Medrano

26 November 2019

This paper presents a fully integrated Gm–C low pass filter (LPF) based on a current steering Gm reduction-tuning technique, specifically designed to operate as the output stage of a SoC lock-in amplifier. To validate this proposal, a first-ord...

  • Article
  • Open Access
809 Views
11 Pages

Thermal management is an area of study in electronics focused on managing temperature to improve reliability and efficiency. When temperatures are too high, cooling systems are activated to prevent overheating, which can lead to reliability issues. T...

  • Article
  • Open Access
9 Citations
8,668 Views
20 Pages

27 February 2023

This paper introduces a digital interface application-specific integrated circuit (ASIC) for a micro-electromechanical systems (MEMS) vibratory gyroscope. The driving circuit of the interface ASIC uses an automatic gain circuit (AGC) module instead o...

  • Article
  • Open Access
1 Citations
3,462 Views
18 Pages

On-Chip Structures for Fmax Binning and Optimization

  • Dongrong Zhang,
  • Qiang Ren and
  • Donglin Su

11 February 2022

Process variations during manufacturing lead to differences in the performance of the chips. In order to better utilize the performance of the chips, it is necessary to perform maximum operation frequency (Fmax) tests to place the chips into differen...

  • Article
  • Open Access
2 Citations
1,699 Views
14 Pages

This paper presents a novel high-precision 11-bit single-slope/successive approximation register analog-to-digital converter (SS/SAR ADC) architecture specifically designed for CMOS image sensors (CISs). The proposed design solves critical challenges...

  • Proceeding Paper
  • Open Access
2,228 Views
4 Pages

On-Chip Temperature Compensation for Thermal Impedance Sensors

  • Martin Jaegle,
  • Hans-Fridtjof Pernau,
  • Marcus Pfützner,
  • Mike Benkendorf,
  • Xinke Li,
  • Markus Bartel,
  • Susanne Drost and
  • Jürgen Wöllenstein

27 November 2018

Electrical impedance spectroscopy is a widespread characterization method for solids or fluids in industrial applications. We here report on its thermal equivalent, the “thermal impedance spectroscopy”, improved by using a temperature compensation me...

  • Article
  • Open Access
16 Citations
8,302 Views
14 Pages

30 January 2016

This paper proposes the first all-digital on-chip linearity enhancement technique for improving the accuracy of the time-domain complementary metal-oxide semiconductor (CMOS) smart temperature sensor. To facilitate on-chip application and intellectua...

  • Proceeding Paper
  • Open Access
2,525 Views
4 Pages

Evanescent Waveguide Sensor for On-Chip Biomolecular Detection

  • Giampiero de Cesare,
  • Rita Asquini,
  • Alessio Buzzin and
  • Domenico Caputo

This work presents analysis and development of an evanescent waveguide sensor system, which integrates an amorphous silicon photodiode and a glass-diffused waveguide. Design of the system includes a study of thickness and refractive index of the tran...

  • Article
  • Open Access
17 Citations
13,159 Views
16 Pages

Laser Doppler Blood Flow Imaging Using a CMOS Imaging Sensor with On-Chip Signal Processing

  • Diwei He,
  • Hoang C. Nguyen,
  • Barrie R. Hayes-Gill,
  • Yiqun Zhu,
  • John A. Crowe,
  • Cally Gill,
  • Geraldine F. Clough and
  • Stephen P. Morgan

18 September 2013

The first fully integrated 2D CMOS imaging sensor with on-chip signal processing for applications in laser Doppler blood flow (LDBF) imaging has been designed and tested. To obtain a space efficient design over 64 × 64 pixels means that standard proc...

  • Article
  • Open Access
27 Citations
16,846 Views
16 Pages

MW-PPG Sensor: An on-Chip Spectrometer Approach

  • Cheng-Chun Chang,
  • Chien-Ta Wu,
  • Byung Il Choi and
  • Tong-Jing Fang

26 August 2019

Multi-wavelength photoplethysmography (MW-PPG) sensing technology has been known to be superior to signal-wavelength photoplethysmography (SW-PPG) sensing technology. However, limited by the availability of sensing detectors, many prior studies can o...

  • Article
  • Open Access
10 Citations
12,228 Views
14 Pages

An Impedance-Based Mold Sensor with on-Chip Optical Reference

  • Poornachandra Papireddy Vinayaka,
  • Sander Van den Driesche,
  • Roland Blank,
  • Muhammad Waseem Tahir,
  • Mathias Frodl,
  • Walter Lang and
  • Michael J. Vellekoop

28 September 2016

A new miniaturized sensor system with an internal optical reference for the detection of mold growth is presented. The sensor chip comprises a reaction chamber provided with a culture medium that promotes the growth of mold species from mold spores....

  • Article
  • Open Access
46 Citations
18,185 Views
24 Pages

6 March 2015

An ultra-low power CMOS image sensor with on-chip energy harvesting and power management capability is introduced in this paper. The photodiode pixel array can not only capture images but also harvest solar energy. As such, the CMOS image sensor chip...

  • Feature Paper
  • Article
  • Open Access
5 Citations
4,180 Views
17 Pages

A Reactive and On-Chip Sensor Circuit for NBTI and PBTI Resilient SRAM Design

  • Nandakishor Yadav,
  • Youngbae Kim,
  • Mahmoud Alashi and
  • Kyuwon Ken Choi

Process Variation (PV), Bias Temperature Instability (BTI) and Time-Dependent Dielectric Breakdown (TDDB) are the critical factors that affect the reliability of semiconductor chip design. They cause the system to be unstable and increase the soft er...

  • Article
  • Open Access
3 Citations
3,063 Views
14 Pages

Highly Sensitive On-Chip Grating-Based Optical Sensor on Glass Substrate: Cost-Effective Design

  • Hesham A. Attia,
  • Mulan E. Ahmed,
  • Adel Shaaban Awad Elsharkawi and
  • Mohamed A. Swillam

22 February 2024

This paper presents a novel on-chip optical sensing system using ion exchange technology and phase-shifted Bragg grating design. The sensor geometry has been optimized using a finite difference time domain (FDTD) solver to achieve maximum sensitivity...

  • Article
  • Open Access
1 Citations
7,884 Views
17 Pages

This paper presents an on-chip temperature sensor circuit for dynamic thermal management in VLSI systems. The sensor directly senses the threshold voltage that contains temperature information using a single PMOS device. This simple structure enables...

  • Article
  • Open Access
3 Citations
6,342 Views
17 Pages

13 February 2015

An all-digital on-chip delay sensor (OCDS) circuit with high delay-measurement resolution and low supply-voltage sensitivity for efficient detection and diagnosis in high-performance electronic system applications is presented. Based on the proposed...

  • Article
  • Open Access
7 Citations
6,184 Views
18 Pages

A High-Speed Low-Cost VLSI System Capable of On-Chip Online Learning for Dynamic Vision Sensor Data Classification

  • Wei He,
  • Jinguo Huang,
  • Tengxiao Wang,
  • Yingcheng Lin,
  • Junxian He,
  • Xichuan Zhou,
  • Ping Li,
  • Ying Wang,
  • Nanjian Wu and
  • Cong Shi

21 August 2020

This paper proposes a high-speed low-cost VLSI system capable of on-chip online learning for classifying address-event representation (AER) streams from dynamic vision sensor (DVS) retina chips. The proposed system executes a lightweight statistic al...

  • Article
  • Open Access
36 Citations
10,223 Views
24 Pages

Design and Characterization of a Sensorized Microfluidic Cell-Culture System with Electro-Thermal Micro-Pumps and Sensors for Cell Adhesion, Oxygen, and pH on a Glass Chip

  • Sebastian M. Bonk,
  • Marco Stubbe,
  • Sebastian M. Buehler,
  • Carsten Tautorat,
  • Werner Baumann,
  • Ernst-Dieter Klinkenberg and
  • Jan Gimsa

30 July 2015

We combined a multi-sensor glass-chip with a microfluidic channel grid for the characterization of cellular behavior. The grid was imprinted in poly-dimethyl-siloxane. Mouse-embryonal/fetal calvaria fibroblasts (MC3T3-E1) were used as a model system....

  • Article
  • Open Access
1 Citations
7,196 Views
16 Pages

39 fJ/bit On-Chip Identification ofWireless Sensors Based on Manufacturing Variation

  • Jonathan F. Bolus,
  • Benton H. Calhoun and
  • Travis N. Blalock

A 39 fJ/bit IC identification system based on FET mismatch is presented and implemented in a 130 nm CMOS process. ID bits are generated based on the ΔVT between identically drawn NMOS devices due to manufacturing variation, and the ID cell structure...

  • Article
  • Open Access
16 Citations
10,460 Views
9 Pages

7 February 2011

The application of a waveguide-ring resonator based on dielectric-loaded surface plasmon-polariton waveguides as a temperature sensor is demonstrated in this paper and the influence of temperature change to the transmission through the waveguide-ring...

  • Article
  • Open Access
9 Citations
4,159 Views
12 Pages

13 December 2022

Blood testing is a clinical diagnostic tool to evaluate physiological conditions, the immune system response, or the presence of infection from whole blood samples. Although conventional blood testing can provide rich biological information, it usual...

  • Article
  • Open Access
1 Citations
1,790 Views
21 Pages

2 October 2024

This paper presents a thorough robust Class-AB power amplifier design and its application in pressure-mode sensor-on-chip nonlinearity correction. Considering its use in piezoresistive sensing applications, a gain-boosting-aided folded cascode struct...

  • Article
  • Open Access
17 Citations
10,718 Views
21 Pages

Statistical Analysis of the Random Telegraph Noise in a 1.1 μm Pixel, 8.3 MP CMOS Image Sensor Using On-Chip Time Constant Extraction Method

  • Calvin Yi-Ping Chao,
  • Honyih Tu,
  • Thomas Meng-Hsiu Wu,
  • Kuo-Yu Chou,
  • Shang-Fu Yeh,
  • Chin Yin and
  • Chih-Lin Lee

23 November 2017

A study of the random telegraph noise (RTN) of a 1.1 μm pitch, 8.3 Mpixel CMOS image sensor (CIS) fabricated in a 45 nm backside-illumination (BSI) technology is presented in this paper. A noise decomposition scheme is used to pinpoint the noise sour...

  • Article
  • Open Access
3 Citations
1,554 Views
13 Pages

In this work, we developed 3D ionic liquid (IL) functionalized graphene assemblies (GAs) decorated by ultrafine RuCu alloy nanoparticles (RuCu-ANPs) via a one-step synthesis process, and integrated it into a microfluidic sensor chip for in situ elect...

  • Article
  • Open Access
9 Citations
3,655 Views
13 Pages

Polymer Waveguide Sensor Based on Evanescent Bragg Grating for Lab-on-a-Chip Applications

  • Zhenyu Zhang,
  • Ahmad Abdalwareth,
  • Günter Flachenecker,
  • Martin Angelmahr and
  • Wolfgang Schade

15 February 2024

In this work, an evanescent Bragg grating sensor inscribed in a few-mode planar polymer waveguide was integrated into microchannel structures and characterized by various chemical applications. The planar waveguide and the microchannels consisted of...

  • Article
  • Open Access
17 Citations
10,653 Views
21 Pages

26 August 2016

The remarkable advantages micro-chip platforms offer over cumbersome, time-consuming equipment currently in use for bio-analysis are well documented. In this research, a micro-chip that includes a unique magnetic actuator (MA) for the manipulation of...

  • Article
  • Open Access
14 Citations
3,823 Views
20 Pages

Smart homes assist users by providing convenient services from activity classification with the help of machine learning (ML) technology. However, most of the conventional high-performance ML algorithms require relatively high power consumption and m...

  • Article
  • Open Access
2 Citations
2,341 Views
12 Pages

A Microfluidic-Based Sensing Platform for Rapid Quality Control on Target Cells from Bioreactors

  • Alessia Foscarini,
  • Fabio Romano,
  • Valeria Garzarelli,
  • Antonio Turco,
  • Alessandro Paolo Bramanti,
  • Iolena Tarantini,
  • Francesco Ferrara,
  • Paolo Visconti,
  • Giuseppe Gigli and
  • Maria Serena Chiriacò

16 November 2024

We investigated the design and characterization of a Lab-On-a-Chip (LoC) cell detection system primarily designed to support immunotherapy in cancer treatment. Immunotherapy uses Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) to fight...

  • Article
  • Open Access
3 Citations
4,109 Views
18 Pages

7 November 2022

Platinum dissolution in PEM fuel cells is an increasingly important indicator for the state-of-health and lifetime prediction of fuel cells in real applications. For this reason, portable online analysis tools are needed that can detect and quantify...

  • Article
  • Open Access
1 Citations
4,528 Views
17 Pages

12 August 2022

The surveillance cameras we focus on target the volume zone, and area reduction is a top priority. However, by simplifying the ADC comparator, we face a new RUSH current issue, for which we propose a circuit solution. This paper proposes two novel te...

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