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Various On-Chip Sensors with Microfluidics for Biological Applications

Department of Electrical Engineering, University at Buffalo, State University of New York (SUNY at Buffalo), Buffalo, NY 14260, USA
Author to whom correspondence should be addressed.
Sensors 2014, 14(9), 17008-17036;
Received: 15 July 2014 / Revised: 29 August 2014 / Accepted: 10 September 2014 / Published: 12 September 2014
(This article belongs to the Special Issue On-Chip Sensors)
In this paper, we review recent advances in on-chip sensors integrated with microfluidics for biological applications. Since the 1990s, much research has concentrated on developing a sensing system using optical phenomena such as surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) to improve the sensitivity of the device. The sensing performance can be significantly enhanced with the use of microfluidic chips to provide effective liquid manipulation and greater flexibility. We describe an optical image sensor with a simpler platform for better performance over a larger field of view (FOV) and greater depth of field (DOF). As a new trend, we review consumer electronics such as smart phones, tablets, Google glasses, etc. which are being incorporated in point-of-care (POC) testing systems. In addition, we discuss in detail the current optical sensing system integrated with a microfluidic chip. View Full-Text
Keywords: SPR; SERS; image sensor; smart phone; microfluidic chip SPR; SERS; image sensor; smart phone; microfluidic chip
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MDPI and ACS Style

Lee, H.; Xu, L.; Koh, D.; Nyayapathi, N.; Oh, K.W. Various On-Chip Sensors with Microfluidics for Biological Applications. Sensors 2014, 14, 17008-17036.

AMA Style

Lee H, Xu L, Koh D, Nyayapathi N, Oh KW. Various On-Chip Sensors with Microfluidics for Biological Applications. Sensors. 2014; 14(9):17008-17036.

Chicago/Turabian Style

Lee, Hun; Xu, Linfeng; Koh, Domin; Nyayapathi, Nikhila; Oh, Kwang W. 2014. "Various On-Chip Sensors with Microfluidics for Biological Applications" Sensors 14, no. 9: 17008-17036.

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