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11,927 Results Found

  • Article
  • Open Access
1 Citations
2,764 Views
20 Pages

27 June 2023

Coastal social–ecological systems (SES), particularly in large bays, are critical for fisheries, transportation, and disaster prevention in island and coastal countries. To achieve the sustainability of such bays, public involvement is recently...

  • Article
  • Open Access
6 Citations
3,309 Views
11 Pages

Views of the Future of Partners of People with Multiple Sclerosis Who Attended a Lifestyle Modification Workshop: A Qualitative Analysis of Perspectives and Experiences

  • Sandra L. Neate,
  • Keryn L. Taylor,
  • Nupur Nag,
  • George A. Jelinek,
  • Steve Simpson-Yap,
  • William Bevens and
  • Tracey J. Weiland

People with multiple sclerosis (PwMS) often experience uncertainty and fear about their futures. Partners of PwMS may share their concerns and experience fears about their own futures, limitations on their lives, ability to work, and becoming a carer...

  • Article
  • Open Access
26 Citations
3,232 Views
26 Pages

21 August 2022

In the Industrial Internet of Things (IIoT), non-orthogonal multiple access (NOMA) has emerged as a viable multiple access method due to its superior efficiency. In this paper, a new power allocation technique for NOMA-enabled IIoT devices is present...

  • Review
  • Open Access
38 Citations
9,261 Views
14 Pages

17 October 2016

Using the term of progressive multiple sclerosis (PMS), we considered a combined population of persons with secondary progressive MS (SPMS) and primary progressive MS (PPMS). These forms of MS cannot be challenged with efficacy by the licensed therap...

  • Article
  • Open Access
1 Citations
3,399 Views
16 Pages

16 October 2023

The concept of Future Work-Salience (FWSS) plays a pivotal role in ensuring sustainable employability. Previous studies on FWSS have primarily focused on career-related outcomes, neglecting the broader domain of proactive behaviors. Furthermore, the...

  • Review
  • Open Access
28 Citations
6,368 Views
26 Pages

Risk Assessment of Combined Exposure to Multiple Chemicals at the European Food Safety Authority: Principles, Guidance Documents, Applications and Future Challenges

  • Irene Cattaneo,
  • Alexander D. Kalian,
  • Matteo R. Di Nicola,
  • Bruno Dujardin,
  • Sara Levorato,
  • Luc Mohimont,
  • Alexis V. Nathanail,
  • Edoardo Carnessechi,
  • Maria Chiara Astuto and
  • Jose V. Tarazona
  • + 7 authors

4 January 2023

Human health and animal health risk assessment of combined exposure to multiple chemicals use the same steps as single-substance risk assessment, namely problem formulation, exposure assessment, hazard assessment and risk characterisation. The main u...

  • Article
  • Open Access
18 Citations
5,022 Views
15 Pages

The Multi-Aspect Criterion in the PMADM Outline and Its Possible Application to Sustainability Assessment

  • Sarfaraz Hashemkhani Zolfani,
  • Edmundas Kazimieras Zavadskas,
  • Payam Khazaelpour and
  • Fausto Cavallaro

27 November 2018

Over the past few centuries, the process of decision-making has become more complicated in different respects. Since the initial phase of Multiple Criteria Decision Making (MCDM) around fifty years ago, Multiple Attribute Decision Making (MADM) has c...

  • Article
  • Open Access
57 Citations
16,520 Views
21 Pages

Using Scenario Visioning and Participatory System Dynamics Modeling to Investigate the Future: Lessons from Minnesota 2050

  • Laura K. Schmitt Olabisi,
  • Anne R. Kapuscinski,
  • Kris A. Johnson,
  • Peter B. Reich,
  • Brian Stenquist and
  • Kathryn J. Draeger

24 August 2010

Both scenario visioning and participatory system dynamics modeling emphasize the dynamic and uncontrollable nature of complex socio-ecological systems, and the significance of multiple feedback mechanisms. These two methodologies complement one anoth...

  • Article
  • Open Access
3 Citations
2,834 Views
17 Pages

20 September 2024

As urban expansion continues, the intensifying land surface temperature (LST) underscores the critical need for accurate predictions of future thermal environments. However, no study has investigated which method can most effectively and consistently...

  • Article
  • Open Access
6 Citations
4,118 Views
27 Pages

Foresight Based on MADM-Based Scenarios’ Approach: A Case about Comprehensive Sustainable Health Financing Models

  • Sarfaraz Hashemkhani Zolfani,
  • Reza Dehnavieh,
  • Atousa Poursheikhali,
  • Olegas Prentkovskis and
  • Payam Khazaelpour

27 December 2019

As indicated by a worldwide common perspective about health and sustainable health systems, the health structure as a part of public health is a key theme of many societies. The future is shaped by probable future scenarios, for which dealing practic...

  • Article
  • Open Access
4 Citations
1,773 Views
21 Pages

Against the backdrop of increasing financialization of grain markets, the cross-cycle and cross-market contagion among commodities has been intensifying. To investigate the risk spillover among commodities across different cycles, this study selected...

  • Article
  • Open Access
4 Citations
3,306 Views
18 Pages

9 October 2021

The governance of the global marine ecological environment is closely related to human life and needs to adopt a multisubject co-governance system. There is a lack of understanding of the need for co-governance by multiple subjects for global marine...

  • Review
  • Open Access
43 Citations
7,574 Views
44 Pages

Multi-Objective Planning Techniques in Distribution Networks: A Composite Review

  • Syed Ali Abbas Kazmi,
  • Muhammad Khuram Shahzad and
  • Dong Ryeol Shin

12 February 2017

Distribution networks (DNWs) are facing numerous challenges, notably growing load demands, environmental concerns, operational constraints and expansion limitations with the current infrastructure. These challenges serve as a motivation factor for va...

  • Article
  • Open Access
5 Citations
4,528 Views
25 Pages

27 December 2017

We employ the DEMATEL-based analytic network process (D-ANP) to evaluate the weight of various factors on S&P 500 index futures. The general regression method is employed to prove the result. We then employed grey relational analysis (GRA) to exa...

  • Review
  • Open Access
22 Citations
10,685 Views
26 Pages

Neurorehabilitation in Multiple Sclerosis—A Review of Present Approaches and Future Considerations

  • Carmen Adella Sîrbu,
  • Dana-Claudia Thompson,
  • Florentina Cristina Plesa,
  • Titus Mihai Vasile,
  • Dragoș Cătălin Jianu,
  • Marian Mitrica,
  • Daniela Anghel and
  • Constantin Stefani

27 November 2022

Multiple sclerosis is an increasingly prevalent disease, representing the leading cause of non-traumatic neurological disease in Europe and North America. The most common symptoms include gait deficits, balance and coordination impairments, fatigue,...

  • Article
  • Open Access
424 Views
27 Pages

SWIPT Enabled Wavelet Cooperative NOMA: Energy-Efficient Design Under Imperfect SIC

  • Uzma Mushtaq,
  • Asim Ali Khan,
  • Sobia Baig,
  • Muneeb Ahmad and
  • Moisés V. Ribeiro

11 November 2025

In new wireless ecosystems, simultaneous wireless information and power transfer (SWIPT) and cooperative non-orthogonal multiple access (CNOMA) together make a potential design model. These systems enhance spectral efficiency (SE), energy efficiency...

  • Article
  • Open Access
7 Citations
4,369 Views
17 Pages

This article investigates the effectiveness of TAIEX (Taiwan Stock Exchange) futures, Taiwan 50 futures, and nonfinance nonelectronics subindex (NFNE) futures for cross hedging the price risk of stock sector indices traded on the Taiwan stock exchang...

  • Article
  • Open Access
12 Citations
7,526 Views
19 Pages

25 April 2014

This study proposes a multiple kernel learning (MKL)-based regression model for crude oil spot price forecasting and trading. We used a well-known trend-following technical analysis indicator, the moving average convergence and divergence (MACD) indi...

  • Review
  • Open Access
19 Citations
5,164 Views
17 Pages

Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research

  • Claudia Massarotti,
  • Elvira Sbragia,
  • Irene Gazzo,
  • Sara Stigliani,
  • Matilde Inglese and
  • Paola Anserini

19 November 2021

Multiple sclerosis is a chronic disease that may lead to different types of symptoms and disabilities. with the better quality of life and decreased disability due to early diagnosis and the availability of disease-modifying therapies (DMTs), the tre...

  • Review
  • Open Access
26 Citations
6,356 Views
27 Pages

Past, Present, and a Glance into the Future of Multiple Myeloma Treatment

  • Weam Othman Elbezanti,
  • Kishore B. Challagundla,
  • Subash C. Jonnalagadda,
  • Tulin Budak-Alpdogan and
  • Manoj K. Pandey

Multiple myeloma (MM) is a challenging hematological cancer which typically grows in bone marrow. MM accounts for 10% of hematological malignancies and 1.8% of cancers. The recent treatment strategies have significantly improved progression-free surv...

  • Perspective
  • Open Access
27 Citations
7,856 Views
13 Pages

Tremor in Multiple Sclerosis—An Overview and Future Perspectives

  • Karim Makhoul,
  • Rechdi Ahdab,
  • Naji Riachi,
  • Moussa A. Chalah and
  • Samar S. Ayache

12 October 2020

Tremor is an important and common symptom in patients with multiple sclerosis (MS). It constituted one of the three core features of MS triad described by Charcot in the last century. Tremor could have a drastic impact on patients’ quality of life. T...

  • Review
  • Open Access
5 Citations
4,893 Views
27 Pages

The present paper reviews available background information for studying multiple stressor effects of radon (222Rn) and phthalates in children and provides insights on future directions. In realistic situations, living organisms are collectively subje...

  • Review
  • Open Access
10 Citations
5,376 Views
15 Pages

Future Directions in Maintenance Therapy in Multiple Myeloma

  • Sarah A. Holstein,
  • Vera J. Suman,
  • Jens Hillengass and
  • Philip L. McCarthy

24 May 2021

Autologous stem cell transplantation (ASCT) has been a backbone of therapy for newly diagnosed patients with multiple myeloma eligible for high-dose therapy for decades. Survival outcomes have continued to improve over time, in part because of the in...

  • Article
  • Open Access
338 Views
29 Pages

MTP-STG: Spatio-Temporal Graph Transformer Networks for Multiple Future Trajectory Prediction in Crowds

  • Zichen Zhang,
  • Xingwen Cao,
  • Yi Song,
  • Wenjie Gong,
  • Liyu Zhang,
  • Yanzhen Zhang,
  • Yingxiang Li and
  • Haoran Zhang

8 December 2025

Predicting multiple future pedestrian trajectories is a challenging task for real-world applications like autonomous driving and robotic motion planning. Existing methods primarily focus on immediate spatial interactions among pedestrians, often over...

  • Review
  • Open Access
52 Citations
16,926 Views
13 Pages

The global incidence of multiple sclerosis (MS) appears to be increasing. Although it may not be associated with a high mortality rate, this disease has a high morbidity rate which affects the quality of life of patients and reduces their ability to...

  • Review
  • Open Access
17 Citations
12,426 Views
32 Pages

Imaging of Multiple Myeloma: Present and Future

  • Víctor Rodríguez-Laval,
  • Blanca Lumbreras-Fernández,
  • Beatriz Aguado-Bueno and
  • Nieves Gómez-León

2 January 2024

Multiple myeloma (MM) is the second most common adult hematologic malignancy, and early intervention increases survival in asymptomatic high-risk patients. Imaging is crucial for the diagnosis and follow-up of MM, as the detection of bone and bone ma...

  • Review
  • Open Access
5 Citations
3,362 Views
14 Pages

Current and Future PET Imaging for Multiple Myeloma

  • Mariko Ishibashi,
  • Miwako Takahashi,
  • Taiga Yamaya and
  • Yoichi Imai

7 August 2023

Positron emission tomography (PET) is an imaging modality used for the noninvasive assessment of tumor staging and response to therapy. PET with 18F labeled fluorodeoxyglucose (18F-FDG PET) is widely used to assess the active and inactive lesions in...

  • Perspective
  • Open Access
3 Citations
8,921 Views
13 Pages

20 February 2023

Salt intake is associated with multiple sclerosis; however, controversial findings that challenge this association rely primarily on methods that do not measure total sodium storage within the body, such as food surveys and urinary sodium excretion....

  • Article
  • Open Access
655 Views
17 Pages

20 July 2025

Our study focused on identifying the evolution of soil erosion and its key drivers under multiple future scenarios in the Yiluo River Basin. Integrating the Universal Soil Loss Equation (USLE), future land use and vegetation cover simulation methods,...

  • Article
  • Open Access
14 Citations
7,048 Views
17 Pages

4 February 2019

Pediatric-onset multiple sclerosis (POMS) is relatively rare, but as technology and neuroimaging advance, an increasing number of cases are identified, and our understanding of how multiple sclerosis (MS) impacts the developing brain improves. There...

  • Review
  • Open Access
6 Citations
3,171 Views
13 Pages

Bortezomib Pharmacogenetic Biomarkers for the Treatment of Multiple Myeloma: Review and Future Perspectives

  • Antonio Sanz-Solas,
  • Jorge Labrador,
  • Raquel Alcaraz,
  • Beatriz Cuevas,
  • Raquel Vinuesa,
  • María Victoria Cuevas and
  • Miriam Saiz-Rodríguez

20 April 2023

Multiple myeloma (MM) is a hematological neoplasm for which different chemotherapy treatments are used with several drugs in combination. One of the most frequently used drugs for the treatment of MM is the proteasome inhibitor bortezomib. Patients t...

  • Article
  • Open Access
7 Citations
3,057 Views
10 Pages

Suicide is listed in the top ten causes of death in Taiwan. Previous studies have pointed out that psychiatric patients having suicide attempts in their history are more likely to attempt suicide again than non-psychiatric patients. Therefore, how to...

  • Perspective
  • Open Access
9 Citations
6,956 Views
23 Pages

4 February 2025

Colorectal cancer (CRC) is the third most common cancer and is associated with a poor prognosis. The mutation profile and related involved pathways of CRC have been, in broad terms, analyzed. The main current therapeutic approaches have been comprehe...

  • Review
  • Open Access
9 Citations
4,778 Views
11 Pages

26 August 2022

Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease of the central nervous system, often presenting with brain atrophy and cognitive impairment (CI). In the relapsing–remitting phenotype, cognitive performance is increasing...

  • Review
  • Open Access
2 Citations
4,291 Views
12 Pages

17 January 2023

Urban systems include complex interactions and interdependencies with adjoining landscapes and regions. The pressures of change are complex, constant, and increasing. Declining biodiversity, ecosystem function, social institutions, and climate change...

  • Review
  • Open Access
2,903 Views
56 Pages

Multiple Myeloma and Precursor Plasma Cell Disorders: From Emerging Driver Mutations to Current and Future Therapeutic Strategies

  • Henry Sutanto,
  • Pradana Zaky Romadhon,
  • Vembi Rizky Fatmawati,
  • Alief Waitupu,
  • Bagus Aditya Ansharullah,
  • Betty Rachma,
  • Elisa Elisa,
  • Laras Pratiwi and
  • Galih Januar Adytia

18 August 2025

Multiple myeloma (MM) is a malignant plasma cell disorder that evolves from precursor conditions including monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). Understanding the biological continuum and the...

  • Review
  • Open Access
19 Citations
9,050 Views
19 Pages

Lenalidomide in Multiple Myeloma: Review of Resistance Mechanisms, Current Treatment Strategies and Future Perspectives

  • Piotr Kulig,
  • Sławomir Milczarek,
  • Estera Bakinowska,
  • Laura Szalewska,
  • Bartłomiej Baumert and
  • Bogusław Machaliński

2 February 2023

Multiple myeloma (MM) is the second most common hematologic malignancy, accounting for approximately 1% of all cancers. Despite the initial poor prognosis for MM patients, their life expectancy has improved significantly with the development of novel...

  • Review
  • Open Access
11 Citations
5,814 Views
11 Pages

A Scoping Review of Modifiable Risk Factors in Pediatric Onset Multiple Sclerosis: Building for the Future

  • Julie Pétrin,
  • Maximillian D.J. Fiander,
  • Prenitha Mercy Ignatius Arokia Doss and
  • E. Ann Yeh

26 October 2018

Knowledge of the effect of modifiable lifestyle factors in the pediatric multiple sclerosis (MS) population is limited. We therefore conducted a scoping review, following the framework provided by Arksey and O’Malley. Four databases were searched for...

  • Article
  • Open Access
7 Citations
3,105 Views
8 Pages

15 April 2021

The purpose was to study the risk of rupture of unruptured intracranial aneurysms (UIAs) of patients with multiple intracranial aneurysms after subarachnoid hemorrhage (SAH), in a long-term follow-up study, from variables known at baseline. Future ru...

  • Review
  • Open Access
1 Citations
2,016 Views
18 Pages

Reducing Stigma, Enhancing Psychological Well-Being and Identity in Multiple Sclerosis: A Narrative Review of Current Practices and Future Directions

  • Cristina Montesano,
  • Giulia Liberali,
  • Gianluca Azzali,
  • Cosme Buzzachera,
  • Sonia Angilletta,
  • Marco Alessandria,
  • Laura Guidetti and
  • Andrea De Giorgio

Background: Stigma is a pervasive, though understudied, psychosocial factor affecting people with multiple sclerosis. This review synthesizes the literature on the impact of perceived, enacted, and internalized stigma on psychological health and illn...

  • Review
  • Open Access
9 Citations
9,285 Views
32 Pages

This paper offers an in-depth review of the latest advancements in the automatic generation of medical case-based multiple-choice questions (MCQs). The automatic creation of educational materials, particularly MCQs, is pivotal in enhancing teaching e...

  • Article
  • Open Access
5 Citations
4,395 Views
16 Pages

30 May 2020

Biogas is expected to contribute 10% of the total renewable energy use in Europe in 2030. This expectation largely depends on the use of several biomass byproducts and wastes as feedstocks. However, the current development of a biobased economy requi...

  • Article
  • Open Access
10 Citations
2,600 Views
18 Pages

27 December 2023

Climate change and land use/cover change (LUCC) are two major factors that alter hydrological processes. The upper reaches of the Tarim River, situated in the northwest region of China, experience a dry and less rainy climate and are significantly in...

  • Article
  • Open Access
10 Citations
3,109 Views
26 Pages

14 February 2022

The integration of future grid customers, e.g., electric vehicles, heat pumps, or photovoltaic modules, will challenge existing low-voltage power grids in the upcoming years. Hence, distribution system operators must quantify future grid reinforcemen...

  • Article
  • Open Access
19 Citations
8,121 Views
43 Pages

Artificial intelligence-enabled adaptive learning systems (AI-ALS) have been increasingly utilized in education. Schools are usually afforded the freedom to deploy the AI-ALS that they prefer. However, even before artificial intelligence autonomously...

  • Review
  • Open Access
104 Citations
13,163 Views
27 Pages

Current and Future Biomarkers in Multiple Sclerosis

  • Jennifer Yang,
  • Maysa Hamade,
  • Qi Wu,
  • Qin Wang,
  • Robert Axtell,
  • Shailendra Giri and
  • Yang Mao-Draayer

Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of effective treatment for the progressive form of MS, partly due to insensitive readout for neurodegeneration. The recent development of sensitive assays for n...

  • Editorial
  • Open Access
1 Citations
1,912 Views
5 Pages

8 July 2023

Multiple sclerosis (MS) is one of the most common inflammatory neurological diseases which leads to a highly heterogeneous set of symptoms and signs due to the differential involvement of the motor, sensory, visual, and autonomic systems [...]

  • Editorial
  • Open Access
3 Citations
1,821 Views
3 Pages

Multiple Sclerosis and Demyelinating Disorders: Past, Present, and Future

  • Christos Bakirtzis,
  • Maria Elephteria Evangelopoulos and
  • Nikolaos Grigoriadis

22 September 2024

In the past two decades, there has been a considerable increase of our knowledge with regards to the pathophysiology and management of various demyelinating diseases of the central nervous system [...]

  • Article
  • Open Access
13 Citations
4,718 Views
16 Pages

Projection of Future Drought Characteristics under Multiple Drought Indices

  • Muhammad Imran Khan,
  • Xingye Zhu,
  • Xiaoping Jiang,
  • Qaisar Saddique,
  • Muhammad Saifullah,
  • Yasir Niaz and
  • Muhammad Sajid

29 April 2021

Drought is a natural phenomenon caused by the variability of climate. This study was conducted in the Songhua River Basin of China. The drought events were estimated by using the Reconnaissance Drought Index (RDI) and Standardized Precipitation Index...

  • Review
  • Open Access
16 Citations
7,746 Views
36 Pages

27 October 2023

The landscape of therapeutic measures to treat multiple myeloma has undergone a seismic shift since the dawn of the current century. This has been driven largely by the introduction of new classes of small molecules, such as proteasome blockers (e.g....

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