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A Scoping Review of Modifiable Risk Factors in Pediatric Onset Multiple Sclerosis: Building for the Future
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Children 2019, 6(2), 21; https://doi.org/10.3390/children6020021

Cognitive Functioning in Patients with Pediatric-Onset Multiple Sclerosis, an Updated Review and Future Focus

1
Department of Neurology, Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, 1001 Main St., Buffalo, NY 14203, USA
2
Department of Psychology, Roosevelt University, 430 S Michigan Ave, Chicago, IL 60605, USA
*
Author to whom correspondence should be addressed.
Received: 2 January 2018 / Revised: 28 January 2019 / Accepted: 31 January 2019 / Published: 4 February 2019
(This article belongs to the Special Issue Multiple Sclerosis and Demyelinating Disorders in Children)
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PDF [299 KB, uploaded 4 February 2019]
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Abstract

Pediatric-onset multiple sclerosis (POMS) is relatively rare, but as technology and neuroimaging advance, an increasing number of cases are identified, and our understanding of how multiple sclerosis (MS) impacts the developing brain improves. There are consistent findings in the literature highlighting the impact of MS and other demyelinating diseases on cognitive functioning and cognitive development. We also have a better understanding of how POMS impacts psychosocial functioning and functional outcomes in daily living. This paper hopes to review findings associated with cognitive and psychosocial functioning in patients with POMS, as well as explore more recent advances in the field and how they relate to cognitive and psychosocial outcomes. We also discuss the ongoing need for future studies with a focus on better understanding deficits and disease correlates, but also preventative measures and potential rehabilitation. View Full-Text
Keywords: multiple sclerosis; demyelinating disorder; pediatric; cognitive; neuropsychology; psychosocial multiple sclerosis; demyelinating disorder; pediatric; cognitive; neuropsychology; psychosocial
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Parrish, J.B.; Fields, E. Cognitive Functioning in Patients with Pediatric-Onset Multiple Sclerosis, an Updated Review and Future Focus. Children 2019, 6, 21.

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