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20,009 Results Found

  • Article
  • Open Access
6 Citations
3,460 Views
18 Pages

12 November 2021

Various studies on latency in remote mixed reality collaborations (remote MR collaboration) have been conducted, but studies related to interaction latency are scarce. Interaction latency in a remote MR collaboration occurs because action detection (...

(This article belongs to the Special Issue Augmented Reality: Trends, Challenges and Prospects)
  • Article
  • Open Access
18 Citations
3,898 Views
17 Pages

Vehicle Interaction Behavior Prediction with Self-Attention

  • Linhui Li,
  • Xin Sui,
  • Jing Lian,
  • Fengning Yu and
  • Yafu Zhou

7 January 2022

The structured road is a scene with high interaction between vehicles, but due to the high uncertainty of behavior, the prediction of vehicle interaction behavior is still a challenge. This prediction is significant for controlling the ego-vehicle. W...

(This article belongs to the Section Vehicular Sensing)
  • Article
  • Open Access
1,395 Views
21 Pages

Drug–Target Interaction Prediction via Dual-Interaction Fusion

  • Xingyang Li,
  • Zepeng Li,
  • Bo Wei and
  • Yuni Zeng

31 January 2026

Accurate prediction of drug–target interaction (DTI) is crucial for modern drug discovery. However, experimental assays are costly, and many existing computational models still face challenges in capturing multi-scale features, fusing cross-mod...

  • Article
  • Open Access
2 Citations
2,985 Views
25 Pages

Machine learning research focuses on the improvement of prediction performance. Progress was made with black-box models that flexibly adapt to the given data. However, due to their increased complexity, black-box models are more difficult to interpre...

(This article belongs to the Section Learning)
  • Review
  • Open Access
283 Citations
23,732 Views
15 Pages

Machine Learning for Drug-Target Interaction Prediction

  • Ruolan Chen,
  • Xiangrong Liu,
  • Shuting Jin,
  • Jiawei Lin and
  • Juan Liu

31 August 2018

Identifying drug-target interactions will greatly narrow down the scope of search of candidate medications, and thus can serve as the vital first step in drug discovery. Considering that in vitro experiments are extremely costly and time-consuming, h...

(This article belongs to the Special Issue Molecular Computing and Bioinformatics)
  • Article
  • Open Access
4 Citations
3,177 Views
20 Pages

12 September 2023

Trajectory prediction aims to predict the movement intention of traffic participants in the future based on the historical observation trajectories. For traffic scenarios, pedestrians, vehicles and other traffic participants have social interaction o...

(This article belongs to the Section Vehicular Sensing)
  • Article
  • Open Access
4 Citations
4,991 Views
15 Pages

10 December 2022

Click-through rate prediction is a critical task for computational advertising and recommendation systems, where the key challenge is to model feature interactions between different feature domains. At present, the main click-through rate prediction...

(This article belongs to the Section Sensor Networks)
  • Feature Paper
  • Article
  • Open Access
5 Citations
3,516 Views
17 Pages

Bio-Inspired Mamba for Antibody–Antigen Interaction Prediction

  • Xuan Liu,
  • Haitao Fu,
  • Yuqing Yang and
  • Jian Zhang

Antibody lead discovery, crucial for immunotherapy development, requires identifying candidates with potent binding affinities to target antigens. Recent advances in protein language models have opened promising avenues to tackle this challenge by pr...

(This article belongs to the Special Issue Computational Intelligence in Structure and Function Prediction and Modeling of Proteins—2nd Edition)
  • Article
  • Open Access
6 Citations
3,021 Views
25 Pages

GPU-Accelerated Interaction-Aware Motion Prediction

  • Juan Luis Hortelano,
  • Vinicius Trentin,
  • Antonio Artuñedo and
  • Jorge Villagra

5 September 2023

Before their massive deployment, autonomous vehicles need to prove in complex scenarios such that they can reach human driving proficiency while guaranteeing higher safety levels. One of the most important human traits to negotiating traffic is the a...

(This article belongs to the Section Electrical and Autonomous Vehicles)
  • Article
  • Open Access
921 Views
24 Pages

Pedestrian trajectory prediction remains a challenging task, particularly in long-tail scenarios where goal distributions are sparse and inter-agent behaviors are uncertain. In this work, we propose to disentangle the trajectory prediction task into...

(This article belongs to the Section AI-Driven Innovations)
  • Article
  • Open Access
2 Citations
5,878 Views
24 Pages

26 March 2024

Click-through rate (CTR) prediction plays a crucial role in online services and applications, such as online shopping and advertising. The performance of CTR prediction can have a direct impact on user experience and the revenue of the online platfor...

  • Article
  • Open Access
1 Citations
884 Views
18 Pages

Hierarchical Contrastive Learning for Protein–Protein Interaction Prediction Across Organisms

  • Shiyi Liu,
  • Buwen Liang,
  • Yuetong Fang,
  • Zixuan Jiang and
  • Renjing Xu

With advances in biomedical technologies and the continued expansion of experimental resources, biological data are growing rapidly in both scale and complexity. Contrastive learning provides an effective framework for integrating heterogeneous biolo...

(This article belongs to the Special Issue Artificial Intelligence and Deep Learning in Biomedical and Molecular Research)
  • Article
  • Open Access
2 Citations
2,075 Views
24 Pages

Construction of Virtual Interaction Location Prediction Model Based on Distance Cognition

  • Zhenghong Liu,
  • Huiliang Zhao,
  • Jian Lv,
  • Qipeng Chen and
  • Qiaoqiao Xiong

17 October 2022

Due to the difference in distance cognition between virtual and real symmetric space, it is difficult for users to accurately interact with the target in the Digital Twin system. In order to study the cross-effects of interaction task, target size an...

(This article belongs to the Section F: Engineering and Materials)
  • Article
  • Open Access
55 Citations
7,990 Views
14 Pages

21 February 2022

Concurrent use of multiple drugs can lead to unexpected adverse drug reactions. The interaction between drugs can be confirmed by routine in vitro and clinical trials. However, it is difficult to test the drug–drug interactions widely and effec...

(This article belongs to the Special Issue Disease Prediction and Prevention: From Computational Biology and Artificial Intelligence to Epidemiology and Clinical Sciences)
  • Article
  • Open Access
188 Views
16 Pages

18 October 2026

Genotype, environment, and their interactions collectively determine crop phenotypes. While integrating genotypic and environmental data has the potential to improve genomic prediction performance, most existing methods do not adequately incorporate...

(This article belongs to the Section Crop Genetics, Genomics and Breeding)
  • Article
  • Open Access
83 Citations
7,816 Views
14 Pages

Non-coding RNAs (ncRNAs) play crucial roles in multiple fundamental biological processes, such as post-transcriptional gene regulation, and are implicated in many complex human diseases. Mostly ncRNAs function by interacting with corresponding RNA-bi...

(This article belongs to the Special Issue Computational Models in Non-Coding RNA and Human Disease)
  • Article
  • Open Access
7 Citations
3,505 Views
12 Pages

Prediction of Protein–ligand Interaction Based on Sequence Similarity and Ligand Structural Features

  • Dmitry Karasev,
  • Boris Sobolev,
  • Alexey Lagunin,
  • Dmitry Filimonov and
  • Vladimir Poroikov

31 October 2020

Computationally predicting the interaction of proteins and ligands presents three main directions: the search of new target proteins for ligands, the search of new ligands for targets, and predicting the interaction of new proteins and new ligands. W...

(This article belongs to the Special Issue Medical Genetics, Genomics and Bioinformatics – 2020)
  • Review
  • Open Access
8 Citations
6,971 Views
31 Pages

16 September 2025

Aberrant protein–protein interactions (PPIs) underpin a plethora of human diseases, and disruption of these harmful interactions constitute a compelling treatment avenue. Advances in computational approaches to PPI prediction have closely follo...

(This article belongs to the Section Cellular Biophysics)
  • Article
  • Open Access
36 Citations
6,363 Views
23 Pages

Combining drugs, a phenomenon often referred to as polypharmacy, can induce additional adverse effects. The identification of adverse combinations is a key task in pharmacovigilance. In this context, in silico approaches based on machine learning are...

(This article belongs to the Special Issue The Prediction of Pharmacokinetics/Pharmacodynamics Using In-Silico Modeling)
  • Article
  • Open Access
9 Citations
2,158 Views
20 Pages

9 February 2024

With the rapid development of the web service market, the number of web services shows explosive growth. QoS is an important factor in the recommendation scene; how to accurately recommend a high-quality service for users among the massive number of...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
40 Citations
8,236 Views
21 Pages

22 December 2021

Protein–protein interactions (PPIs) perform various functions and regulate processes throughout cells. Knowledge of the full network of PPIs is vital to biomedical research, but most of the PPIs are still unknown. As it is infeasible to discove...

(This article belongs to the Special Issue Protein-Protein Interactions 2021)
  • Article
  • Open Access
7 Citations
3,022 Views
11 Pages

Pantograph–Catenary Interaction Prediction Model Based on SCSA-RBF Network

  • Mengzhen Wu,
  • Xianghong Xu,
  • Haochen Zhang,
  • Rui Zhou and
  • Jianshan Wang

4 January 2024

As a traditional numerical simulation method for pantograph–catenary interaction research, the pantograph–catenary finite element model cannot be applied to the real-time monitoring of pantograph–catenary contact force, and the comp...

  • Article
  • Open Access
43 Citations
9,746 Views
19 Pages

9 August 2021

Predicting the trajectories of surrounding vehicles by considering their interactions is an essential ability for the functioning of autonomous vehicles. The subsequent movement of a vehicle is decided based on the multiple maneuvers of surrounding v...

(This article belongs to the Topic Intelligent Transportation Systems)
  • Article
  • Open Access
9 Citations
3,008 Views
15 Pages

26 September 2025

Background: Drug–drug interactions (DDIs) involve pharmacokinetic or pharmacodynamic changes that occur when multiple drugs are co-administered, potentially leading to reduced efficacy or adverse effects. As polypharmacy becomes more prevalent,...

(This article belongs to the Section Drug Discovery, Development and Delivery)
  • Article
  • Open Access
22 Citations
4,079 Views
16 Pages

24 October 2022

Cellular functions are governed by proteins, and, while some proteins work independently, most work by interacting with other proteins. As a result it is crucially important to know the interaction sites that facilitate the interactions between the p...

(This article belongs to the Section Molecular Informatics)
  • Article
  • Open Access
12 Citations
5,349 Views
17 Pages

27 September 2021

The global growing population is experiencing challenges to satisfy the food chain supply in a world that faces rapid changes in environmental conditions complicating the development of stable cultivars. Emergent methodologies aided by molecular mark...

(This article belongs to the Section Crop Genetics, Genomics and Breeding)
  • Article
  • Open Access
813 Views
26 Pages

Deep learning methods have been extensively used for drug–drug interaction (DDI) prediction, aiding the development of effective and safe combination therapies. Most studies focus on either the internal molecular structure or external contextua...

  • Article
  • Open Access
7 Citations
2,528 Views
20 Pages

18 October 2024

Accurate pedestrian trajectory prediction is crucial in many fields. This requires the full use and learning of pedestrians’ social interactions, movements, and environmental information. In view of the current research on pedestrian trajectory...

(This article belongs to the Special Issue Advanced, Smart, and Sustainable Transportation)
  • Article
  • Open Access
5 Citations
4,884 Views
19 Pages

2 September 2022

Potential drug toxicities and drug interactions of redundant compounds of plant complexes may cause unexpected clinical responses or even severe adverse events. On the other hand, super-additivity of drug interactions between natural products and syn...

(This article belongs to the Special Issue Computational Studies of Drugs and Biomolecules)
  • Article
  • Open Access
16 Citations
3,121 Views
22 Pages

Weather Interaction-Aware Spatio-Temporal Attention Networks for Urban Traffic Flow Prediction

  • Hua Zhong,
  • Jian Wang,
  • Cai Chen,
  • Jianlong Wang and ,
  • Dong Li and
  • Kailin Guo
  • + 1 author+ 0 author

29 February 2024

As the cornerstone of intelligent transportation systems, accurate traffic prediction can reduce the pressure of urban traffic, reduce the cost of residents’ travel time, and provide a reference basis for urban construction planning. Existing t...

(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
  • Article
  • Open Access
12 Citations
4,190 Views
11 Pages

Prediction of Protein–Ligand Interaction Based on the Positional Similarity Scores Derived from Amino Acid Sequences

  • Dmitry Karasev,
  • Boris Sobolev,
  • Alexey Lagunin,
  • Dmitry Filimonov and
  • Vladimir Poroikov

The affinity of different drug-like ligands to multiple protein targets reflects general chemical–biological interactions. Computational methods estimating such interactions analyze the available information about the structure of the targets,...

(This article belongs to the Special Issue Medical Genetics, Genomics and Bioinformatics)
  • Article
  • Open Access
12 Citations
3,307 Views
15 Pages

12 August 2022

Nowadays, drug–target interactions (DTIs) prediction is a fundamental part of drug repositioning. However, on the one hand, drug–target interactions prediction models usually consider drugs or targets information, which ignore prior knowl...

(This article belongs to the Section Computational and Theoretical Chemistry)
  • Review
  • Open Access
16 Citations
4,569 Views
15 Pages

22 January 2019

Prediction of walking turns allows to improve human factors such as comfort and perceived safety in human-robot interaction. The current state-of-the-art suggests that upper body kinematics can be used for that purpose and contains evidence about the...

  • Article
  • Open Access
1 Citations
873 Views
23 Pages

12 March 2026

As the maritime industry transitions towards green shipping, operational sustainability and energy efficiency are increasingly crucial for long-endurance Unmanned Surface Vehicle (USV) missions. To this end, proactively adjusting driving strategies b...

  • Article
  • Open Access
26 Citations
6,009 Views
13 Pages

Variable Admittance Control Based on Trajectory Prediction of Human Hand Motion for Physical Human-Robot Interaction

  • Yu Wang,
  • Yuanyuan Yang,
  • Baoliang Zhao,
  • Xiaozhi Qi and ,
  • Ying Hu,
  • Bing Li,
  • Lining Sun,
  • Lihai Zhang and
  • Max Q.-H. Meng
  • + 4 authors+ 0 author

18 June 2021

In order to achieve effective physical human–robot interaction, human dynamic characteristics needs to be considered in admittance control. This paper proposes a variable admittance control method for physical human–robot interaction based on traject...

(This article belongs to the Section Mechanical Engineering)
  • Article
  • Open Access
28 Citations
4,862 Views
19 Pages

20 November 2018

The interaction between the gird and wind farms has significant impact on the power grid, therefore prediction of the interaction between gird and wind farms is of great significance. In this paper, a wind turbine-gird interaction prediction model ba...

(This article belongs to the Special Issue Solar and Wind Energy Forecasting)
  • Article
  • Open Access
2 Citations
2,039 Views
19 Pages

Se-xDeepFEFM: Combining Low-Order Feature Refinement and Interaction Intensity Evaluation for Click-Through Rate Prediction

  • Guangli Li,
  • Guangxin Xu,
  • Guangting Wu,
  • Yiyuan Ye and ,
  • Chuanxiu Li,
  • Hongbin Zhang and
  • Donghong Ji
  • + 2 authors+ 0 author

12 October 2022

Click-through rate (CTR) prediction can provide considerable economic and social benefits. Few studies have considered the importance of low-order features, usually employing a simple feature interaction method. To address these issues, we propose a...

(This article belongs to the Section A: Computer Science)
  • Article
  • Open Access
8 Citations
3,428 Views
15 Pages

9 January 2023

Drug-target interaction prediction provides important information that could be exploited for drug discovery, drug design, and drug repurposing. Chemogenomic approaches for predicting drug-target interaction assume that similar receptors bind to simi...

  • Article
  • Open Access
14 Citations
3,583 Views
17 Pages

NFSA-DTI: A Novel Drug–Target Interaction Prediction Model Using Neural Fingerprint and Self-Attention Mechanism

  • Feiyang Liu,
  • Huang Xu,
  • Peng Cui,
  • Shuo Li and ,
  • Hongbo Wang and
  • Ziye Wu
  • + 1 author+ 0 author

3 November 2024

Existing deep learning methods have shown outstanding performance in predicting drug–target interactions. However, they still have limitations: (1) the over-reliance on locally extracted features by some single encoders, with insufficient consi...

(This article belongs to the Special Issue Molecular Computer Science and Artificial Intelligence for Drug Discovery)
  • Article
  • Open Access
57 Citations
8,043 Views
16 Pages

The treatment of complex diseases by using multiple drugs has become popular. However, drug-drug interactions (DDI) may give rise to the risk of unanticipated adverse effects and even unknown toxicity. Therefore, for polypharmacy safety it is crucial...

(This article belongs to the Section Computational and Theoretical Chemistry)
  • Article
  • Open Access
8 Citations
3,367 Views
31 Pages

19 November 2022

Traditional building energy consumption prediction methods lack the description of occupant behaviors. The interactions between occupants and equipment have great influence on building energy consumption, which cause a large deviation between the pre...

(This article belongs to the Special Issue Building Energy System Planning and Operation)
  • Article
  • Open Access
9 Citations
3,335 Views
24 Pages

5 September 2025

Reliable prediction of chemical–protein interactions (CPIs) remains a key challenge in drug discovery, especially under sparse or noisy biological data. We present MM-TCoCPIn, a Multi-Modal Topology-aware Chemical–Protein Interaction Netw...

(This article belongs to the Section Molecular Informatics)
  • Article
  • Open Access
3 Citations
3,193 Views
10 Pages

Prediction of Intact N-Glycopeptide Retention Time Windows in Hydrophilic Interaction Liquid Chromatography

  • Petr Kozlik,
  • Katarina Molnarova,
  • Tomas Jecmen,
  • Tomas Krizek and
  • Zuzana Bosakova

Analysis of protein glycosylation is challenging due to micro- and macro-heterogeneity of the attached glycans. Hydrophilic interaction liquid chromatography (HILIC) is a mode of choice for separation of intact glycopeptides, which are inadequately r...

(This article belongs to the Special Issue Protein Analysis by Mass Spectrometry)
  • Article
  • Open Access
5 Citations
1,760 Views
23 Pages

17 December 2025

Vehicle trajectory prediction is a pivotal technology in intelligent transportation systems. Existing methods encounter challenges in effectively modeling lane topology and dynamic interaction relationships in complex traffic scenarios, limiting pred...

(This article belongs to the Special Issue Autonomous Vehicles: Sensing, Mapping, and Positioning)
  • Article
  • Open Access
799 Views
25 Pages

18 June 2026

Existing drug–target interaction (DTI) prediction methods still face challenges caused by sparse interaction data, complex multi-source relationships, and imbalanced information contributions among different nodes. In this study, we propose NAF...

(This article belongs to the Special Issue Computational Pharmacology: Advances in Computational Modeling of Drug–Receptor Interactions and Pharmacokinetics)
  • Article
  • Open Access
12 Citations
4,558 Views
16 Pages

24 December 2023

As a link connecting the environmental perception system and the decision-making system, accurate obstacle trajectory prediction provides a reliable guarantee of correct decision-making by autonomous vehicles. Oriented toward a mixed human-driven and...

(This article belongs to the Special Issue Novel Methods and Technologies for Intelligent Vehicles: 2nd Edition)
  • Feature Paper
  • Article
  • Open Access
8 Citations
3,080 Views
14 Pages

Genomic Prediction Accuracy of Stripe Rust in Six Spring Wheat Populations by Modeling Genotype by Environment Interaction

  • Kassa Semagn,
  • Muhammad Iqbal,
  • Diego Jarquin,
  • Harpinder Randhawa and ,
  • Reem Aboukhaddour,
  • Reka Howard,
  • Izabela Ciechanowska,
  • Momna Farzand,
  • Raman Dhariwal and
  • Dean Spaner
  • + 8 authors+ 3 authors

30 June 2022

Some previous studies have assessed the predictive ability of genome-wide selection on stripe (yellow) rust resistance in wheat, but the effect of genotype by environment interaction (GEI) in prediction accuracies has not been well studied in diverse...

(This article belongs to the Special Issue Biotechnological Resources for Improvement of Disease Resistance and Nutritional Quality in Staple Crops)
  • Review
  • Open Access
1,931 Views
36 Pages

Machine Learning and Deep Learning Frameworks for Human–Virus Protein–Protein Interaction Prediction: Emerging Architectures, Methods, Benchmarks, and Challenges

  • Subhadeep Basu,
  • Dipanwita Adhikary,
  • Kuntal Ghosh,
  • Swarup Chattopadhyay and ,
  • Shramana Deb,
  • Ritwick Mondal,
  • Jayanta Roy,
  • Anjan Chowdhury and
  • Julián Benito-León
  • + 4 authors+ 0 author

The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged as one of the most significant global health crises in recent history. Coronaviruses are a diverse group of RNA v...

(This article belongs to the Special Issue 25th Anniversary of IJMS: Updates and Advances in Molecular Informatics)
  • Article
  • Open Access
2 Citations
530 Views
28 Pages

Software defect prediction (SDP) aims to identify defect-prone modules before testing, but severe class imbalance and redundant software metrics often limit prediction performance. Many conventional feature selection methods estimate feature relevanc...

(This article belongs to the Special Issue Next-Generation Imbalanced Learning: Trustworthiness, Scalability, and Representation: A Special Issue Dedicated to the Memory of Prof. Barbara Pes)
  • Article
  • Open Access
292 Views
26 Pages

Graph-Interaction-Prediction-Based Planning of Safe Flight Intervals and Dynamic 3D Paths for UAVs

  • Haiming Sun,
  • Shangju She,
  • Feng Peng,
  • Chuan Sun and ,
  • Haoran Li and
  • Xiaoqiu Zheng
  • + 1 author+ 0 author

6 October 2026

To address the challenge of directly translating predicted distributions of dynamic obstacles into three-dimensional (3D) planning constraints during unmanned aerial vehicle (UAV) flight, we propose Torch GIP-RB-SI-3DA*, a graph-interaction-predictio...

(This article belongs to the Topic Data-Driven Optimization for Smart Urban Mobility)

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