Raman spectroscopy plays a critical role in planetary exploration by providing detailed analysis of mineralogical and chemical compositions. However, the conventional point-focused Raman systems, while precise, are limited by their time-consuming nat...
This article summarizes the field of focused ultrasound for use in neuromodulation and discusses different ways of targeting, delivering, and validating focused ultrasound. A discussion is focused on parameter space and different ongoing theories of...
Beauty treatment for skin requires a high-intensity focused ultrasound (HIFU) transducer to generate coagulative necrosis in a small focal volume (e.g., 1 mm3) placed at a shallow depth (3–4.5 mm from the skin surface). For this, it is desirable to m...
We present a single element-based dual focused photoacoustic microscopy (PAM) that shows improved signal-to-noise ratio and lateral resolution compared to conventional single focused PAM in the out-of-focus region. This dual focused PAM is based on t...
Focused ultrasound (FUS) has emerged as a promising noninvasive therapeutic modality for treating atherosclerotic arterial disease. High-intensity focused ultrasound (HIFU), a noninvasive and precise modality that generates high temperatures at speci...
18 December 2020
The health problems of North Korean (NK) refugees living a new life after surviving the dangers of life and death traumas is an issue that must be taken very seriously. Adolescent refugees may be particularly vulnerable to adverse physical and mental...
Sarcomas are tumors of mesenchymal origin that are generally resistant to systemic therapies and prone to local recurrence despite current multimodal treatment approaches. Focused ultrasound (FUS) is a noninvasive therapeutic technology that may enha...
Temporal intent is an important component of events. It plays an important role in collecting them from the web with focused crawlers. However, traditionally focused crawlers usually only consider factors such as topic keywords, web page content, and...
In this paper, diffraction of scalar waves by a screen with a circular aperture is explored, considering the incidence of either a collimated beam or a focused wave, a historical review of the development of the theory is presented, and the introduct...
Employing the full arsenal of therapeutics to treat brain tumors is limited by the relative impermeability of the blood–brain and blood–tumor barriers. In physiologic states, the blood–brain barrier serves a protective role by passi...
Focused ultrasound is a novel technique for the treatment of aggressive brain tumors that uses both mechanical and thermal mechanisms. This non-invasive technique can allow for both the thermal ablation of inoperable tumors and the delivery of chemot...
Infiltrating gliomas are challenging to treat, as the blood-brain barrier significantly impedes the success of therapeutic interventions. While some clinical trials for high-grade gliomas have shown promise, patient outcomes remain poor. Microbubble-...
For 80 years, high-intensity focused ultrasound (HIFU) has been the subject of interest in medical research. It is a non-invasive procedure that causes the death of cells in a very select area through one of two mechanisms, either heat or cavitation....
Medical product sponsors are encouraged to include the patient perspective in their medical product development strategy to inform product design, augment regulatory submissions, argue for alternative clinical trial designs, or to support indications...
Submerged horizontal plates are widely employed in research of wave structure interaction as a simplification of coastal and ocean engineering structures. The hydrodynamic performance of submerged horizontal plates under focused waves has been seldom...
For the more efficient application of ultrasound in future therapies, fundamental research is needed on the mode of action of ultrasound on biological systems using therapeutic frequencies. To address this need, a new versatile high-throughput platfo...
Traditional cancer treatments have not significantly improved the survival rates for individuals with colorectal cancer. As a result, there is a dire need to explore novel treatment modalities that can target cancer-specific niches, transform cold co...
Simultaneous spatial and temporal focusing (SSTF) of femtosecond laser pulses gives rise to strong suppression of nonlinear self-focusing during the propagation of the femtosecond laser beam. In this paper, we begin with an introduction of the princi...
Recent works on focused ultrasound (FUS) have shown great promise for cancer therapy. Researchers are continuously trying to improve system performance, which is resulting in an increased complexity that is more apparent when using multi-element phas...
Ultrasound hyperthermia is a medical treatment used to increase temperature of tissues. It can be used independently or as a supportive method for an anticancer treatment. The therapeutic efficacy of focused ultrasound hyperthermia can be improved us...
Background: It is unclear as to where we stand with respect to utilizing emerging focused ultrasound (FUS) technology in the setting of brain tumor treatment in pediatric patients, such as malignant diffuse intrinsic pontine glioma, and various adult...
In this contribution, we compare the performance of Focused Electron Beam-induced Deposition (FEBID) and Focused Ion Beam-induced Deposition (FIBID) at room temperature and under cryogenic conditions (the prefix “Cryo” is used here for cryogenic). Un...
We present a modeling study of photoinitiated polymerization in a thick polymer-absorbing medium using a focused UV laser. Transient profiles of the initiator concentration at various focusing conditions are analyzed to define the polymerization boun...
Transcranial MR-guided Focused ultrasound (tcMRgFUS) is a surgical procedure that adopts focused ultrasounds beam towards a specific therapeutic target through the intact skull. The convergence of focused ultrasound beams onto the target produces tis...
The focused ion beam (FIB) is a powerful piece of technology which has enabled scientific and technological advances in the realization and study of micro- and nano-systems in many research areas, such as nanotechnology, material science, and the mic...
We consider the use of focused incident near-field (NF) beams to interrogate the object of interest (OI) in NF microwave imaging (MWI). To this end, we first discuss how focused NF beams can be advantageously utilized to suppress scattering effects f...
Focused electron beam induced deposition (FEBID) is a direct-write nanofabrication technique able to pattern three-dimensional magnetic nanostructures at resolutions comparable to the characteristic magnetic length scales. FEBID is thus a powerful to...
Place name is an important ingredient of borderlands situation information and plays a significant role in collecting them from the Internet with focused crawlers. However, current focused crawlers treat place name in the same way as any other common...
Since its discovery in 1911, superconductivity has represented an equally inciting and fascinating field of study in several areas of physics and materials science, ranging from its most fundamental theoretical understanding, to its practical applica...
All-in-focused image combination is a fusion technique used to acquire related data from a set of focused images at different depth levels, which suggests that one can determine objects in the foreground and background regions. When attempting to rec...
Chemotherapy as an adjuvant therapy that has largely failed to significantly improve outcomes for aggressive brain tumors; some reasons include a weak blood brain barrier penetration and tumor heterogeneity. Recently, there has been interest in desig...
Liposomes are microspheres produced by placing phospholipids in aqueous solutions. Liposomes have the advantage of being able to encapsulate both hydrophilic and hydrophobic functional substances and are thus important mediators used in cosmetics and...
In this paper, enhanced rotational circulation in a circular microfluidic chamber driven by dual focused surface-acoustic-wave (SAW) beams is presented. To characterize the resonant frequency and focusing effect, we simulate the focused SAW field exc...
In this work, a focused ultrasonic radiator is proposed for cooling the electrical heating elements in the focal region, and its working characteristics are investigated. The analyses of the FEM computational and flow field visualization test results...
A focused crawler automatically retrieves, organizes, and extracts specific topic-related information from the internet for analysis and application. Currently, most focused crawlers assess the relevance of web pages to a given topic through methods...
Since December 2019, the new SARS-CoV-2-related COVID-19 disease has caused a global pandemic and shut down the public life worldwide. Several proteins have emerged as potential therapeutic targets for drug development, and we sought out to review th...
Traditional oncological interventions have failed to improve survival for pancreatic cancer patients significantly. Novel treatment modalities able to release cancer-specific antigens, render immunologically “cold” pancreatic tumours &ldq...
Skeletal muscle consists of long plurinucleate and contractile structures, able to regenerate and repair tissue damage by their resident stem cells: satellite cells (SCs). Reduced skeletal muscle regeneration and progressive atrophy are typical featu...
Amid the strain related to the necessity of distance learning and related organizational adjustments in higher education institutions (HEIs), this paper re-examines the problem-focused coping strategy and its efficiency in addressing work-related str...
Vaginal laxity (VL) and genitourinary syndromes of menopause (GSM) create physical, psychological, and functional problem for women and their partners. We aimed to evaluate the efficacy and safety of micro-focused ultrasound (MFU) therapy performed t...
The availability of miniaturized ultrasound machines has changed our approach to many cardiovascular diseases. Handheld ultrasound imaging can be performed at the bedside, it is easy to use, and the information provided, although limited, is of unque...
This review provides an introduction to high-intensity focused ultrasound (HIFU) and reviews its historical and current use in urological surgery. Current and historical literature (1927–2020), including that describing trials and review articles in...
A wide range of strategies have been developed to modulate dysfunctional brain activities. This narrative review provides a comparative analysis of biophysical, genetic, and biological neuromodulation approaches with an emphasis on their known or unk...
Focused ultrasound (FUS) is an emerging noninvasive technology with significant therapeutic potential across various clinical domains. FUS enables precise targeting of tissues using mechanisms like thermoablation, mechanical disruption, and neuromodu...
The energy of a focused acoustic field is quite concentrated, and the ability of an acoustic vortex formed by a concave focusing transducer array to capture objects in a flowing medium remains to be investigated. In this paper, the focused pressure d...
29 May 2022
Very little is known about the cognitive functioning of people with body-focused repetitive behaviours and the few existing studies provide mixed findings. The aim of this study was to investigate the interplay between attentional control, negative a...
While emotion-focused therapy (EFT) offers clinically useful information to Christian practitioners, its underlying worldview, epistemology, and emphasis present challenges for Christian therapists. This article advocates that Christian practitioners...
Gasification of peat and lignite under a focused light flow was observed in a wide range of fuel moisture (up to 65 wt.%). The initial water content in the fuels under study had a different influence on the chemical composition of the synthesis gas (...
Background: Compassion-focused therapy (CFT) has been attracting attention in mental health practice and research. CFT is effective in reducing a variety of negative mental health symptoms. Positive mental health (PMH) focuses on an individual’...
This article reviews the state-of-the -art of mechanical material properties and measurement methods of nanostructures obtained by two nanoscale additive manufacturing methods: gas-assisted focused electron and focused ion beam-induced deposition usi...
of 2,628