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881 Results Found

  • Article
  • Open Access
9 Citations
2,158 Views
12 Pages

22 June 2023

Starch-like polymers can be created through the use of enzymatic modification with glycogen branching enzymes (GBEs). GBEs are categorized in the glycoside hydrolase (GH) family 13 and 57. Both GH13 and GH57 GBEs exhibit branching and hydrolytic acti...

  • Article
  • Open Access
5 Citations
3,459 Views
38 Pages

8 October 2023

This paper incorporates flexible facility capacity and government subsidy factors into the consideration of the design of a closed-loop supply chain(CLSC) network based on an uncertain environment. Considering the minimization of economic cost and ca...

  • Review
  • Open Access
4 Citations
8,738 Views
42 Pages

2 July 2025

The rapid advancement of flexible sensor technology has profoundly transformed neural interface research, enabling multimodal information acquisition, real-time neurochemical and electrophysiological signal monitoring, and adaptive closed-loop regula...

  • Article
  • Open Access
4 Citations
4,412 Views
15 Pages

Simple Selection Procedure to Distinguish between Static and Flexible Loops

  • Karolina Mitusińska,
  • Tomasz Skalski and
  • Artur Góra

Loops are the most variable and unorganized elements of the secondary structure of proteins. Their ability to shift their shape can play a role in the binding of small ligands, enzymatic catalysis, or protein–protein interactions. Due to the lo...

  • Article
  • Open Access
1 Citations
1,182 Views
20 Pages

28 September 2025

This paper presents a hardware-in-the-loop (HIL) simulation case study on the application of High-Order Sliding Mode Control (HOSMC) to a flexible-link robotic arm. The developed HIL platform combines physical hardware components with a simulated pla...

  • Article
  • Open Access
11 Citations
5,683 Views
18 Pages

Exploring the Conformational Space of Bcl-2 Protein Variants: Dynamic Contributions of the Flexible Loop Domain and Transmembrane Region

  • Luis A. Caro-Gómez,
  • Jorge L. Rosas-Trigueros,
  • Edgar Mixcoha,
  • José L. Vique-Sánchez,
  • Humberto Gasperin-Sánchez,
  • Claudia G. Benítez-Cardoza and
  • Absalom Zamorano-Carillo

29 October 2019

Members of the Bcl-2 protein family regulate apoptosis through interactions with several proteins. A critical intrinsically disordered region (IDR) present in some members of the Bcl-2 family is essential for their function. Also, the structural and...

  • Article
  • Open Access
239 Views
14 Pages

28 January 2026

Lactulose, a valuable functional disaccharide with pharmaceutical and food applications, is efficiently synthesized via enzymatic isomerization of lactose. This study developed an integrated strategy combining protein engineering of cellobiose 2-epim...

  • Article
  • Open Access
1 Citations
1,628 Views
14 Pages

The fiber-optical current transformer (FOCT) is the core measuring equipment of the flexible DC converter station, which affects the operation control of the system. In order to solve the problem of the influence of the abnormal FOCT on the operation...

  • Article
  • Open Access
8 Citations
3,420 Views
9 Pages

3 June 2021

This work presents a simple and flexible method for theoretical calculation of the main structural parameter of weft-knitted fabrics’—the loop length and one of the main characteristics of textile fabrics—area density, which combines physical and eco...

  • Article
  • Open Access
10 Citations
3,412 Views
17 Pages

A Flexible Single Loop Setup for Water-Borne Transient Electromagnetic Sounding Applications

  • Lukas Aigner,
  • Philipp Högenauer,
  • Matthias Bücker and
  • Adrián Flores Orozco

5 October 2021

Water-borne transient electromagnetic (TEM) soundings provide the means necessary to investigate the geometry and electrical properties of rocks and sediments below continental water bodies, such as rivers and lakes. Most water-borne TEM systems depl...

  • Article
  • Open Access
1 Citations
3,838 Views
12 Pages

Flexible Theoretical Calculation of Loop Length and Area Density of Weft-Knitted Structures: Part II

  • Edgaras Arbataitis,
  • Daiva Mikucioniene,
  • Tetiana Ielina and
  • Liudmyla Halavska

31 August 2021

A simple and flexible method for theoretical calculation of the main structural parameters of various weft-knitted fancy and combined patterns is presented in this article. It is especially important for patterns containing different elements, such a...

  • Article
  • Open Access
14 Citations
4,207 Views
17 Pages

Proving a Concept of Flexible Under-Frequency Load Shedding with Hardware-in-the-Loop Testing

  • Denis Sodin,
  • Rajne Ilievska,
  • Andrej Čampa,
  • Miha Smolnikar and
  • Urban Rudez

13 July 2020

It is widely recognized that in the transition from conventional electrical power systems (EPSs) towards smart grids, electrical voltage frequency will be greatly affected. This is why this research is extremely valuable, especially since rate-of-cha...

  • Article
  • Open Access
2,036 Views
12 Pages

29 April 2024

Addressing peripheral nerve disorders with electronic medicine poses significant challenges, especially in replicating the dynamic mechanical properties of nerves and understanding their functionality. In the field of electronic medicine, it is cruci...

  • Article
  • Open Access
9 Citations
2,232 Views
18 Pages

Evolution of Intrinsic Disorder in Protein Loops

  • Fizza Mughal and
  • Gustavo Caetano-Anollés

14 October 2023

Intrinsic disorder accounts for the flexibility of protein loops, molecular building blocks that are largely responsible for the processes and molecular functions of the living world. While loops likely represent early structural forms that served as...

  • Proceeding Paper
  • Open Access
1,887 Views
8 Pages

In this paper, a novel technique called a “loop fragment” (LF) is developed for structural analysis. A simple method is sufficient for establishing the loop system of framed structures using an original idea, the LF of the loop resultant...

  • Article
  • Open Access
6 Citations
2,869 Views
15 Pages

A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation

  • Claudia Firrito,
  • Cinzia Bertelli,
  • Annachiara Rosa,
  • Ajit Chande,
  • Swetha Ananth,
  • Hannah van Dijk,
  • Oliver T. Fackler,
  • Charlotte Stoneham,
  • Rajendra Singh and
  • Massimo Pizzato
  • + 1 author

28 February 2023

The host transmembrane protein SERINC5 is incorporated into retrovirus particles and inhibits HIV-1 infectivity. The lentiviral Nef protein counteracts SERINC5 by downregulating it from the cell surface and preventing its incorporation into virions....

  • Article
  • Open Access
1 Citations
1,269 Views
14 Pages

To mitigate voltage limit issues in the operation of a novel electromagnetic voltage regulation device, this paper presents a flexible loop-closing control strategy with voltage optimization. The approach uses a two-stage path optimization: in the fi...

  • Article
  • Open Access
9 Citations
2,478 Views
31 Pages

A Novel Control Strategy in Grid-Integrated Photovoltaic System for Power Quality Enhancement

  • Mpho Sam Nkambule,
  • Ali N. Hasan,
  • Ahmed Ali and
  • Thokozani Shongwe

4 August 2022

The integration of solar photovoltaic (PV) systems and utility grids has gradually gained significant interest in improving the sustainability of clean power supply for society. However, power quality remains a challenge due to partial shading condit...

  • Article
  • Open Access
17 Citations
3,812 Views
20 Pages

20 January 2022

As space exploration activities are developing rapidly, spacecraft with large antennas have gained wide acceptance in providing reliable telecommunications and astrophysical observations. In this paper, the dynamic responses and control strategy for...

  • Article
  • Open Access
839 Views
31 Pages

29 August 2025

In order to solve the problem that it is difficult to take into account the performance constraints between the core functions of insulation, current flow and arc extinguishing of high-voltage vacuum circuit breakers at the same time, this paper prop...

  • Article
  • Open Access
3 Citations
1,230 Views
18 Pages

30 March 2025

The anisotropic magnetoresistance (AMR) effect is widely used in microscale and nanoscale magnetic sensors. In this study, we investigate the correlation between AMR and the crystal structure, epitaxial relationship, and magnetic properties of Co50Fe...

  • Feature Paper
  • Article
  • Open Access
2 Citations
1,737 Views
29 Pages

29 July 2025

This work presents an innovative hydrothermal approach for fabricating flexible piezoelectric PZT thin films on 20 μm titanium foil substrates using TiO2 and SrTiO3 (STO) interlayers. Three heterostructures (Ti/PZT, Ti/TiO2/PZT, and Ti/TiO2/STO/PZ...

  • Article
  • Open Access
1,080 Views
15 Pages

Novel Single-Core Phase-Shifting Transformer: Configuration, Analysis and Application in Loop Closing

  • Yong Xu,
  • Fangchen Huang,
  • Yu Diao,
  • Chongze Bi,
  • Xiaokuan Jin and
  • Jianhua Wang

24 August 2025

Phase-shifting transformers (PST) are widely used to control power flows. However, conventional designs can vary only the phase angle, leaving the voltage magnitude unaffected or requiring structurally complex devices. This study proposes a compact P...

  • Article
  • Open Access
10 Citations
3,412 Views
13 Pages

4 September 2023

High-voltage flexible power systems, with their intrinsic characteristics, play an increasingly important role in electronic power systems. Synchronization between the inverter and the grid needs to be achieved by a phase-locked loop (PLL), the perfo...

  • Article
  • Open Access
4 Citations
2,894 Views
22 Pages

Structural and Functional Characterization of Drosophila melanogaster α-Amylase

  • Moez Rhimi,
  • Jean-Luc Da Lage,
  • Richard Haser,
  • Georges Feller and
  • Nushin Aghajari

11 July 2023

Insects rely on carbohydrates such as starch and glycogen as an energy supply for growth of larvae and for longevity. In this sense α-amylases have essential roles under extreme conditions, e.g., during nutritional or temperature stress, thereb...

  • Article
  • Open Access
1 Citations
1,685 Views
18 Pages

15 December 2022

Aiming to achieve fault ride-through (FRT) in a microgrid under the condition of an asymmetric power grid, this paper proposes a scheme that applies the cascaded H-bridge flexible fault current limiter to realize both voltage regulation and current l...

  • Review
  • Open Access
27 Citations
4,941 Views
32 Pages

Solar, Wind and Their Hybridization Integration for Multi-Machine Power System Oscillation Controllers Optimization: A Review

  • Aliyu Sabo,
  • Bashir Yunus Kolapo,
  • Theophilus Ebuka Odoh,
  • Musa Dyari,
  • Noor Izzri Abdul Wahab and
  • Veerapandiyan Veerasamy

20 December 2022

Massive growth in global electrical energy demand has necessitated a genuine exploration and integration of solar and wind energy into the electrical power mix. This incorporation goes a long way in improving the cumulative generated power capacity o...

  • Article
  • Open Access
3 Citations
1,499 Views
16 Pages

A High-Sensitivity Inkjet-Printed Flexible Resonator for Monitoring Dielectric Changes in Meat

  • Jamal Abounasr,
  • Mariam El Gharbi,
  • Raúl Fernández García and
  • Ignacio Gil

22 February 2025

This paper introduces a flexible loop antenna-based sensor optimized for real-time monitoring of meat quality by detecting changes in dielectric properties over a six-day storage period. Operating within the 2.4 GHz ISM band, the sensor is designed u...

  • Article
  • Open Access
22 Citations
5,310 Views
22 Pages

Structural and Functional Analyses of Human ChaC2 in Glutathione Metabolism

  • Yen T. K. Nguyen,
  • Joon Sung Park,
  • Jun Young Jang,
  • Kyung Rok Kim,
  • Tam T. L. Vo,
  • Kyu-Won Kim and
  • Byung Woo Han

24 December 2019

Glutathione (GSH) degradation plays an essential role in GSH homeostasis, which regulates cell survival, especially in cancer cells. Among human GSH degradation enzymes, the ChaC2 enzyme acts on GSH to form 5-l-oxoproline and Cys-Gly specifically in...

  • Article
  • Open Access
3 Citations
3,634 Views
14 Pages

27 November 2018

This note presents an estimation error based disturbance observer (EEDOB) to reduce the effects of external disturbances. In the proposed control structure, a difference between an estimator output and a plant output is considered as an equivalent di...

  • Article
  • Open Access
1 Citations
4,182 Views
15 Pages

Looping Flexible Fluoropolymer Microcapillary Film Extends Analysis Times for Vertical Microfluidic Blood Testing

  • Rüya Meltem Sarıyer,
  • Kirandeep K. Gill,
  • Sarah H. Needs,
  • Nuno M. Reis,
  • Chris I. Jones and
  • Alexander Daniel Edwards

10 September 2024

The microfluidic measurement of capillary flow can be used to evaluate the response of biological samples to stimulation, where distance and velocity are altered. Melt-extruded multi-bored microfluidic capillaries allow for high-throughput testing wi...

  • Article
  • Open Access
5 Citations
6,787 Views
17 Pages

Closing the Loop between Plastic Waste Management and Energy Cogeneration: An Innovative Design for a Flexible Pyrolysis Small-Scale Unit

  • Dimitrios-Aristotelis Koumpakis,
  • Alexandra V. Michailidou,
  • Christos Vlachokostas and
  • Christos Mertzanakis

This study proposes a simplified unit that can be employed in an industrial facility for the utilization of its own abundant plastic waste, primarily from discarded packaging, to achieve full or partial energy autonomy. By converting this waste into...

  • Article
  • Open Access
5 Citations
3,070 Views
15 Pages

Development of a Hardware-in-the-Loop Platform for a Teleoperation Flexibility Robotic System

  • Duc Thien Tran,
  • Tien Dat Nguyen,
  • Minh Khiem Tran and
  • Kyoung Kwan Ahn

6 March 2024

A control method for a cable-driven robot in a teleoperation system is proposed using the hardware-in-the-loop (HIL) simulation technique. The main components of the teleoperated robotic system are a haptic device, also called a delta robot, and a ca...

  • Article
  • Open Access
12 Citations
3,923 Views
15 Pages

Cysteine Mutations in the Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding by Increasing the Flexibility of a Lipid-Binding Loop

  • Kristen A. Johnson,
  • Nisha Bhattarai,
  • Melissa R. Budicini,
  • Carolyn M. LaBonia,
  • Sarah Catherine B. Baker,
  • Bernard S. Gerstman,
  • Prem P. Chapagain and
  • Robert V. Stahelin

15 July 2021

Ebolavirus (EBOV) is a negative-sense RNA virus that causes severe hemorrhagic fever in humans. The matrix protein VP40 facilitates viral budding by binding to lipids in the host cell plasma membrane and driving the formation of filamentous, pleomorp...

  • Article
  • Open Access
6 Citations
3,128 Views
14 Pages

21 November 2023

(1) Lipases are catalysts widely applied in industrial fields. To sustain the harsh treatments in industries, optimizing lipase activities and thermal stability is necessary to reduce production loss. (2) The thermostability of Thermomyces lanuginosu...

  • Article
  • Open Access
4 Citations
3,167 Views
15 Pages

25 September 2022

This study explores how school buildings can be exploited more efficiently in the future, since, at present, they remain unused for a substantial amount of time. One possibility to tackle this inefficiency, is to involve the local community more clos...

  • Article
  • Open Access
8 Citations
3,641 Views
17 Pages

2 February 2021

Due to the micro-vibration of flywheels, the imaging quality of a high-resolution optical remote sensing satellite will be deteriorated, and the micro-vibration effect on the payload is complicated, so it is essential to establish a reasonable and ac...

  • Article
  • Open Access
461 Views
18 Pages

31 March 2025

The rest-to-rest control of a robotic structure having one or more flexible modes while performing a slew maneuver is a challenging problem. In fact, quite a few articles discussed the optimal rest-to-rest slewing solution for various systems. Howeve...

  • Review
  • Open Access
6 Citations
8,959 Views
18 Pages

22 February 2011

Rapid progress of theoretical methods and computer calculation resources has turned in silico methods into a conceivable tool to predict the 3D structure of macromolecular assemblages, starting from the structure of their separate elements. Still, so...

  • Review
  • Open Access
109 Citations
15,799 Views
24 Pages

25 November 2016

Posttranslational modifications are an important feature of most proteases in higher organisms, such as the conversion of inactive zymogens into active proteases. To date, little information is available on the role of glycosylation and functional im...

  • Article
  • Open Access
57 Citations
8,170 Views
29 Pages

27 June 2023

This paper provides a classification of manufacturing types in terms of new technological tools provided in the Industry 5.0 framework. The manufacturing types agile, holonic, flexible and reconfigurable benefit from and are potentially changed by In...

  • Communication
  • Open Access
3,937 Views
4 Pages

4 January 2017

An algorithm is presented for the simulation of two partially flexible macromolecules where the interaction between the flexible parts and rigid parts is represented by energy grids associated with the rigid part of each macromolecule. The proposed a...

  • Review
  • Open Access
15 Citations
6,397 Views
30 Pages

Technological Challenges in the Development of Optogenetic Closed-Loop Therapy Approaches in Epilepsy and Related Network Disorders of the Brain

  • Bram Vandekerckhove,
  • Jeroen Missinne,
  • Kristl Vonck,
  • Pieter Bauwens,
  • Rik Verplancke,
  • Paul Boon,
  • Robrecht Raedt and
  • Jan Vanfleteren

31 December 2020

Epilepsy is a chronic, neurological disorder affecting millions of people every year. The current available pharmacological and surgical treatments are lacking in overall efficacy and cause side-effects like cognitive impairment, depression, tremor,...

  • Review
  • Open Access
20 Citations
10,284 Views
29 Pages

Recycling of Polyurethane Foams via Glycolysis: A Review

  • Kinga Wieczorek,
  • Przemysław Bukowski,
  • Krystian Stawiński and
  • Iwona Ryłko

20 September 2024

Polyurethane foams constitute highly problematic waste due to their low density and consequently large volume. Among the most promising recycling approaches, the glycolysis of polyurethane waste stands out and was extensively discussed in this articl...

  • Article
  • Open Access
791 Views
41 Pages

4 October 2025

Dihydroorotase (DHOase) catalyzes the reversible cyclization of N-carbamoyl-L-aspartate to dihydroorotate, a key step in de novo pyrimidine biosynthesis. A flexible active site loop in DHOase undergoes conformational switching between loop-in and loo...

  • Article
  • Open Access
2,955 Views
8 Pages

The Grimus–Neufeld Model with FlexibleSUSY at One-Loop

  • Simonas Draukšas,
  • Vytautas Dūdėnas,
  • Thomas Gajdosik,
  • Andrius Juodagalvis,
  • Paulius Juodsnukis and
  • Darius Jurčiukonis

16 November 2019

The Grimus–Neufeld model can explain the smallness of measured neutrino masses by extending the Standard Model with a single heavy neutrino and a second Higgs doublet, using the seesaw mechanism and radiative mass generation. The Grimus–L...

  • Article
  • Open Access
1 Citations
2,067 Views
21 Pages

Research on Flexible Braking Control of a Crawler Crane during the Free-Fall Hook Process

  • Wei Gao,
  • Shiheng Song,
  • Guisheng Yang,
  • Chunyi Wang,
  • Yong Wang,
  • Lijuan Chen,
  • Wenqiang Xu and
  • Chao Ai

24 January 2024

Due to the large inertia and strong impact accompanying the free-falling hook process of crawler cranes, it is difficult to meet the demand for flexible and smooth braking control under different weight load conditions. Therefore, this paper takes th...

  • Article
  • Open Access
2 Citations
1,246 Views
18 Pages

Role of Non-Binding T63 Alteration in IL-18 Binding

  • Chariya Peeyatu,
  • Napat Prompat,
  • Supayang Piyawan Voravuthikunchai,
  • Niran Roongsawang,
  • Surasak Sangkhathat,
  • Pasarat Khongkow,
  • Jirakrit Saetang and
  • Varomyalin Tipmanee

3 December 2024

Engineered interleukin-18 (IL-18) has attracted interest as a cytokine-based treatment. However, knowledge-based mutagenesis of IL-18 has been reported for only a few regions of the protein structures, including binding sites I and II. When coupled w...

  • Article
  • Open Access
2,220 Views
19 Pages

25 November 2025

This paper presents a high-voltage step-up DC-DC converter with an active flexible loop based on the Boost topology. By combining interleaved technology, magnetic integration technology, and voltage doubling capacitor technology, the voltage step-up...

  • Article
  • Open Access
8 Citations
6,012 Views
21 Pages

25 November 2021

RuBisCO is the most abundant enzyme on earth; it regulates the organic carbon cycle in the biosphere. Studying its structural evolution will help to develop new strategies of genetic improvement in order to increase food production and mitigate CO2 e...

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