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1,209 Results Found

  • Article
  • Open Access
3 Citations
2,623 Views
13 Pages

Previous research has indicated that Pseudomonas aurantiaca ST-TJ4 possesses a notable antagonistic impact on Phytophthora cinnamomi and holds promising potential for biocontrol. In this study, a combination of a single-factor experiment, a Plackett&...

  • Review
  • Open Access
55 Citations
11,806 Views
25 Pages

Fermentation of Organic Residues to Beneficial Chemicals: A Review of Medium-Chain Fatty Acid Production

  • Panagiota Stamatopoulou,
  • Juliet Malkowski,
  • Leandro Conrado,
  • Kennedy Brown and
  • Matthew Scarborough

28 November 2020

Medium-chain fatty acids (MCFAs) have a variety of uses in the production of industrial chemicals, food, and personal care products. These compounds are often produced through palm refining, but recent work has demonstrated that MCFAs can also be pro...

  • Article
  • Open Access
2,138 Views
13 Pages

Coenzyme Q10 (CoQ10) has attracted widespread attention in recent years due to its momentous physiological functions. Microbial fermentation is the major method in CoQ10 industrial production, and Rhodobacter sphaeroides is the main strain for the pr...

  • Article
  • Open Access
4 Citations
2,904 Views
11 Pages

This study focused on applying a patented medium-chain fatty acids (MCFAs) mixture at the end of alcoholic fermentation and monitoring its residues. MCFAs are a promising agent that has the potential to increase the efficiency of sulfur dioxide and u...

  • Article
  • Open Access
33 Citations
5,131 Views
17 Pages

Improved Neomycin Sulfate Potency in Streptomyces fradiae Using Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis and Fermentation Medium Optimization

  • Fei Yu,
  • Min Zhang,
  • Junfeng Sun,
  • Fang Wang,
  • Xiangfei Li,
  • Yan Liu,
  • Zhou Wang,
  • Xinrui Zhao,
  • Jianghua Li and
  • Zhenglian Xue
  • + 2 authors

To improve the screening efficiency of high-yield neomycin sulfate (NM) Streptomyces fradiae strains after mutagenesis, a high-throughput screening method using streptomycin resistance prescreening (8 μg/mL) and a 24-deep well plates/microplate re...

  • Article
  • Open Access
214 Views
15 Pages

Utilization of Quinoa Post-Fermentation Waste as a Medium for Carotenoid Production by Yeast

  • Ewa Kulczyk-Małysa,
  • Elżbieta Bogusławska-Wąs,
  • Patrycja Jaroszek,
  • Katarzyna Szkolnicka and
  • Artur Rybarczyk

18 January 2026

Carotenoids are a diverse group of isoprenoid compounds found in nature. As natural pigments and bioactive compounds, carotenoids are used in various industries as functional additives. The increasing knowledge about the disadvantages of synthetic ca...

  • Article
  • Open Access
4 Citations
2,704 Views
14 Pages

Evaluation of the In Vitro and In Vivo Antitumor Efficacy of Peanut Sprout Extracts Cultivated with Fermented Sawdust Medium Against Bladder Cancer

  • Hongbeom Park,
  • Jun-Hui Song,
  • Byungdoo Hwang,
  • BoKyung Moon,
  • Seok-Joong Yun,
  • Wun-Jae Kim and
  • Sung-Kwon Moon

7 December 2020

Peanut sprout extracts reportedly exhibit numerous beneficial effects; however, there are few investigations on the biological effects of peanut sprout extracts cultivated with fermented sawdust medium (PSEFS). Here, we examined whether PSEFS demonst...

  • Article
  • Open Access
115 Citations
12,971 Views
13 Pages

27 November 2020

The growing need for Lactobacillus bacteria usage in industry and the expending probiotic market led to a search for new cost-efficient fermentation media from which a high yield of these bacteria could be obtained. The following study aimed to elabo...

  • Article
  • Open Access
20 Citations
6,114 Views
13 Pages

Grape Pomace Extracts as Fermentation Medium for the Production of Potential Biopreservation Compounds

  • Maxwell Mewa-Ngongang,
  • Heinrich W. du Plessis,
  • Seteno K. O. Ntwampe,
  • Boredi S. Chidi,
  • Ucrecia F. Hutchinson,
  • Lukhanyo Mekuto and
  • Neil P. Jolly

2 February 2019

Microbial spoilage causes food losses in the food industry and as such, the use of synthetic chemical preservatives is still required. The current study proposes the use of agro-waste, i.e., grape pomace extracts (GPE), as production medium for biopr...

  • Article
  • Open Access
8 Citations
3,724 Views
15 Pages

Screening and Optimization of Fermentation Medium for Bacillus velezensis BP-1 and Its Biocontrol Effects against Peyronellaea arachidicola

  • Taswar Ahsan,
  • Chunhao Liang,
  • Shuyi Yu,
  • Xue Pei,
  • Jinhui Xie,
  • Ying Lin,
  • Xiaozhou Liu,
  • Muhammad Umair and
  • Chaoqun Zang

7 April 2023

In the submerged fermentation process, the introduction of novel nutrient media as sources of carbon and nitrogen can enhance antifungal activity. In this study, we used a submerged fermentation process to find the optimal media for the Bacillus vele...

  • Article
  • Open Access
3 Citations
3,149 Views
21 Pages

Optimization of Fermentation Culture Medium for Sanghuangporus alpinus Using Response-Surface Methodology

  • Yuhan Gao,
  • Xiaomin Li,
  • Hui Xu,
  • Huijuan Sun,
  • Junli Zhang,
  • Xiaoping Wu and
  • Junsheng Fu

The newly identified Sanghuangporus alpinus species of the Sanghuang mushroom genus has been found to possess significant medical benefits. However, the current artificial cultivation technology has not reached the requisite maturity. The response-su...

  • Article
  • Open Access
7 Citations
6,231 Views
13 Pages

Development of a Molasses-Based Medium for Agrobacterium tumefaciens Fermentation for Application in Plant-Based Recombinant Protein Production

  • Nisit Watthanasakphuban,
  • Luan Van Nguyen,
  • Yu-Shen Cheng,
  • Pau-Loke Show,
  • Malinee Sriariyanun,
  • Mattheos Koffas and
  • Kittipong Rattanaporn

The Agrobacterium-mediated transient gene expression system is a rapid and efficient method for heterologous recombinant protein expression in plants. The fermentation of genetically modified Agrobacterium tumefaciens is an important step in increasi...

  • Article
  • Open Access
7 Citations
2,861 Views
17 Pages

5 October 2022

There are a variety of amino acids and polysaccharides contained in Pleurotus eryngii that can improve immunity and prevent cancer in humans. The purpose of this research was to investigate the improved quality hypha of P. eryngii-3, which could shor...

  • Article
  • Open Access
9 Citations
5,929 Views
16 Pages

Two-Step Optimization for Improving Prodigiosin Production Using a Fermentation Medium for Serratia marcescens and an Extraction Process

  • Xin Wang,
  • Zhihao Cui,
  • Zongyu Zhang,
  • Jiacheng Zhao,
  • Xiaoquan Liu,
  • Guangfan Meng,
  • Jing Zhang and
  • Jie Zhang

Prodigiosin (PG) is a secondary metabolite produced by Serratia marcescens which has a promising future in food, textile, and other industries due to its bright color and diverse biological activities. Currently, the production of PG is mainly restri...

  • Article
  • Open Access
1 Citations
6,291 Views
17 Pages

Optimization of a Bacterial Cultivation Medium via a Design-of-Experiment Approach in a Sartorius Ambr® 15 Fermentation Microbioreactor System

  • Antonio Baccante,
  • Pasquale Petruccelli,
  • Giovanni Saudino,
  • Elena Ragnoni,
  • Erik Johansson,
  • Vito Di Cioccio and
  • Kleanthis Mazarakis

27 November 2023

In the evolving landscape of sustainable biopharmaceutical process development, the utilization of bacteria in the production of various compounds via fermentation has attracted extensive attention from scientists. A successful fermentation process a...

  • Feature Paper
  • Review
  • Open Access
141 Citations
13,921 Views
32 Pages

Medium Chain Carboxylic Acids from Complex Organic Feedstocks by Mixed Culture Fermentation

  • Vicky De Groof,
  • Marta Coma,
  • Tom Arnot,
  • David J Leak and
  • Ana B Lanham

22 January 2019

Environmental pressures caused by population growth and consumerism require the development of resource recovery from waste, hence a circular economy approach. The production of chemicals and fuels from organic waste using mixed microbial cultures (M...

  • Article
  • Open Access
5 Citations
8,715 Views
15 Pages

A major economic obstacle in lignocellulosic ethanol production is the low sugar concentrations in the hydrolysate and subsequent fermentation to economically distillable ethanol concentrations. We have previously demonstrated a two-stage fermentatio...

  • Article
  • Open Access
8 Citations
2,148 Views
10 Pages

Economical Production of Phenazine-1-carboxylic Acid from Glycerol by Pseudomonas chlororaphis Using Cost-Effective Minimal Medium

  • Yu-Xuan Li,
  • Sheng-Jie Yue,
  • Yi-Fan Zheng,
  • Peng Huang,
  • Yan-Fang Nie,
  • Xiang-Rui Hao,
  • Hong-Yan Zhang,
  • Wei Wang,
  • Hong-Bo Hu and
  • Xue-Hong Zhang

27 September 2023

Phenazine compounds are widely used in agricultural control and the medicine industry due to their high inhibitory activity against pathogens and antitumor activity. The green and sustainable method of synthesizing phenazine compounds through microbi...

  • Article
  • Open Access
6 Citations
2,339 Views
12 Pages

To improve the yield of the therapeutic agent N-methylsansalvamide (SA), optimization of stationary liquid fermentation conditions was conducted on an endophytic strain, Fusarium sp. R1, at flask level. Using a One-Factor-At-a-Time approach, the ferm...

  • Article
  • Open Access
4 Citations
4,202 Views
11 Pages

2 March 2022

Organic acids, including acetic acid, are the metabolic products of many microorganisms. Acetic acid is a target product useful in the fermentation process. However, acetic acid has an inhibitory effect on microorganisms and limits fermentation. Thus...

  • Article
  • Open Access
11 Citations
4,795 Views
10 Pages

Influence of the Initial Sugar Concentration and Supplementation with Yeast Extract on Succinic Acid Fermentation in a Lactose-Based Medium

  • Christiane Terboven,
  • Christian Abendroth,
  • Janin Laumer,
  • Christiane Herrmann,
  • Roland Schneider,
  • Patrice Ramm,
  • Joachim Venus and
  • Matthias Plöchl

The aim of this study was to investigate the production of succinic acid from lactose concentrate, a by-product of cheese-making, using Actinobacillus succinogenes and Basfia succiniciproducens. Although the ability of these strains to metabolize dif...

  • Article
  • Open Access
19 Citations
7,054 Views
17 Pages

Medium Optimization and Fermentation Kinetics for κ-Carrageenase Production by Thalassospira sp. Fjfst-332

  • Juanjuan Guo,
  • Longtao Zhang,
  • Xu Lu,
  • Shaoxiao Zeng,
  • Yi Zhang,
  • Hui Xu and
  • Baodong Zheng

5 November 2016

Effective degradation of κ-carrageenan by isolated Thalassospira sp. fjfst-332 is reported for the first time in this paper. It was identified by 16S rDNA sequencing and morphological observation using Transmission Electron Microscopy (TEM). Based on...

  • Review
  • Open Access
9 Citations
2,731 Views
17 Pages

Research on the Resource Recovery of Medium-Chain Fatty Acids from Municipal Sludge: Current State and Future Prospects

  • Yuhao Liu,
  • Yacong Duan,
  • Long Chen,
  • Ziyan Yang,
  • Xiaoli Yang,
  • Shuli Liu and
  • Gangfu Song

The production of municipal sludge is steadily increasing in line with the production of sewage. A wealth of organic contaminants, including nutrients and energy, are present in municipal sludge. Anaerobic fermentation can be used to extract useful r...

  • Article
  • Open Access
862 Views
13 Pages

Cycloheptylprodigiosin exhibits potent anticancer activity through a unique mechanism involving the induction of severe Golgi stress, a previously unrecognized cell death pathway. To increase the prodiginine production from the marine bacterium Spart...

  • Article
  • Open Access
17 Citations
5,977 Views
10 Pages

RETRACTED: In-Situ Yeast Fermentation Medium in Fortifying Protein and Lipid Accumulations in the Harvested Larval Biomass of Black Soldier Fly

  • Chung Yiin Wong,
  • Yeek Chia Ho,
  • Jun Wei Lim,
  • Pau Loke Show,
  • Siewhui Chong,
  • Yi Jing Chan,
  • Chii Dong Ho,
  • Mardawani Mohamad,
  • Ta Yeong Wu and
  • Guan Ting Pan
  • + 1 author

14 March 2020

Recently, worldwide researchers have been focusing on exploiting of black soldier fly larval (BSFL) biomass to serve as the feed mediums for farmed animals, including aquaculture farming, in order to assuage the rising demands for protein sources. In...

  • Article
  • Open Access
2,529 Views
16 Pages

30 September 2025

The fermentation performance of Lactobacillus acidophilus is constrained by factors such as low cell density and fastidious nutritional and environmental requirements, which greatly limit its industrial-scale applications. This study aimed to develop...

  • Article
  • Open Access
6 Citations
3,368 Views
13 Pages

14 July 2022

L-serine is an industrially valuable amino acid that is widely used in the food, cosmetics and pharmaceutical industries. In this study, transcriptome sequencing technology was applied to analyze the changes in gene expression levels during the synth...

  • Communication
  • Open Access
1 Citations
5,334 Views
10 Pages

Biological Stoichiometric Analysis during Substrate Utilization and Secondary Metabolite Production by Non-Saccharomyces Yeasts Using Grape Pomace Extract as Fermentation Medium

  • Maxwell Mewa-Ngongang,
  • Heinrich W. du Plessis,
  • Seteno K. O. Ntwampe,
  • Enoch A. Akinpelu,
  • Ucrecia F. Hutchinson,
  • Boredi S. Chidi,
  • Vincent I. Okudoh and
  • Neil P. Jolly

The emerging interest in the search for alternatives to synthetic preservatives has led to various successful research studies exploring the use of yeasts as potential biological control agents and producers of biopreservatives. The findings that yea...

  • Article
  • Open Access
13 Citations
3,248 Views
14 Pages

26 July 2021

Emodin is a widely distributed anthraquinone derivative with a variety of biological activities, one that can be efficiently produced by marine-derived fungus Aspergillus favipes HN4-13. However, its relatively low fermentation yield limits further d...

  • Article
  • Open Access
18 Citations
4,788 Views
17 Pages

20 November 2022

A novel Bacillus amyloliquefaciens BAM strain, with novel fermentation nutrient mediums and compositions, could produce potent antifungal secondary metabolites, as the existing strains face resistance from fungus pathogens. In the current study, we i...

  • Article
  • Open Access
1,228 Views
22 Pages

Soybean, as a globally important economic crop, is severely threatened by Sclerotinia sclerotiorum, the causative agent of Sclerotinia stem rot (SSR), a major disease in soybean production worldwide, leading to significant yield losses and quality de...

  • Article
  • Open Access
8 Citations
3,510 Views
11 Pages

31 January 2022

Interest in using clays in the diets of ruminants to improve health and performance is increasing. The microbial fermentation of 65:35 (HC) or 35:65 (HF) concentrate:forage feeds, alone or with zeolite (Z), bentonite (B), or sepiolite (S), was studie...

  • Article
  • Open Access
8 Citations
2,718 Views
10 Pages

4 December 2020

This study deals with the effects of the use of a mixture of medium-chain fatty acids (MCFA) at the end of the alcohol fermentation process on the content of carbonyl compounds in wine. During the experiment, the effects of the addition of MCFA at do...

  • Article
  • Open Access
4 Citations
3,087 Views
18 Pages

Lactic acid bacteria (LAB) fermentation is a viable approach for producing plant-based flavour compounds; however, little is understood about the impact of different LAB strains and medium compositions on the production of volatile organic compounds...

  • Article
  • Open Access
6 Citations
4,210 Views
18 Pages

Lichenysin, an amphiphilic biosurfactant with structural and physicochemical properties similar to surfactin, is produced by Bacillus licheniformis. Its low toxicity, good environmental compatibility, solubilization, foaming, emulsification and deter...

  • Article
  • Open Access
16 Citations
6,035 Views
18 Pages

Gas fermentation by acetogens of the genus Clostridium is an attractive technology since it affords the production of biochemicals and biofuels from industrial waste gases while contributing to mitigate the carbon cycle alterations. The acetogenic mo...

  • Article
  • Open Access
2 Citations
1,660 Views
12 Pages

A Comprehensive Investigation of Lipid Profile During the Solid-State Fermentation of Rice by Monascus purpureus

  • Lan Lan,
  • Yimin Cao,
  • Jiajia Yuan,
  • Rui Feng,
  • Huiqin Pan,
  • Xiuhong Mao,
  • Shen Ji,
  • Qing Hu and
  • Heng Zhou

6 February 2025

Red yeast rice is a nutraceutical fermented product used worldwide for the symptomatic relief of dyslipidemia and cardiovascular disease. However, the fermentation-induced lipid transformation from rice to red yeast rice remains unclear. Herein, an u...

  • Article
  • Open Access
1 Citations
2,497 Views
20 Pages

Lactic acid bacteria (LAB) fermentation has been claimed as an effective way of modifying the sensory properties of plant-based foods. However, not much has been published on the influence of different LAB strains on the flavour of the volatile organ...

  • Article
  • Open Access
18 Citations
16,357 Views
10 Pages

Optimization of Sporulation Conditions for Bacillus subtilis BSNK-5

  • Zhiliang Tian,
  • Lizhen Hou,
  • Miao Hu,
  • Yaxin Gao,
  • Danfeng Li,
  • Bei Fan,
  • Fengzhong Wang and
  • Shuying Li

6 June 2022

Bacillus subtilis spores have important biological applications; however, high spore-cell densities and sporulation efficiencies in fermentation is poorly reported. This study systematically analyzed the spore densities and formation efficiency of B....

  • Article
  • Open Access
523 Views
20 Pages

Caproate Production from Yellow Water Fermentation: The Decisive Roles of Electron Donors

  • Kai Shen,
  • Xing Chen,
  • Jiasheng Shi,
  • Xuedong Zhang,
  • Yaya Sun,
  • He Liu,
  • Salma Tabassum and
  • Hongbo Liu

Caproate is a valuable medium-chain fatty acid (MCFA) that is found to be extensively used in biofuel production, food preservation, and the pharmaceutical industries. Short-chain fatty acids (SCFAs) from waste streams can be upgraded sustainably thr...

  • Retraction
  • Open Access
1,754 Views
2 Pages

RETRACTED: Wong et al. In-Situ Yeast Fermentation Medium in Fortifying Protein and Lipid Accumulations in the Harvested Larval Biomass of Black Soldier Fly. Processes 2020, 8, 337

  • Chung Yiin Wong,
  • Yeek Chia Ho,
  • Jun Wei Lim,
  • Pau Loke Show,
  • Siewhui Chong,
  • Yi Jing Chan,
  • Chii Dong Ho,
  • Mardawani Mohamad,
  • Ta Yeong Wu and
  • Guan Ting Pan
  • + 1 author

5 July 2024

The Processes Editorial Office retracts the article titled “RETRACTED: In-Situ Yeast Fermentation Medium in Fortifying Protein and Lipid Accumulations in the Harvested Larval Biomass of Black Soldier Fly” [...]

  • Article
  • Open Access
1 Citations
1,142 Views
18 Pages

Enhancing Gas Fermentation Efficiency via Bioaugmentation with Megasphaera sueciensis and Clostridium carboxidivorans

  • Clemens Hiebl,
  • Dominik Pinner,
  • Hannes Konegger,
  • Franziska Steger,
  • Dina Mohamed and
  • Werner Fuchs

Gas fermentation aims to fix CO2 into higher-value compounds, such as short or medium-chain fatty acids or alcohols. In this context, the use of mixed microbial consortia presents numerous advantages, including increased resilience and adaptability....

  • Article
  • Open Access
14 Citations
4,017 Views
12 Pages

27 October 2020

The strains capable of degrading cellulose have attracted much interest because of their applications in straw resource utilization in solid-state fermentation (SSF). However, achieving high spore production in SSF is rarely reported. The production...

  • Article
  • Open Access
7 Citations
2,340 Views
13 Pages

Optimization of Medium Composition and Fluidized Bed Drying Conditions for Efficient Production of Dry Yeast

  • Hyun-Jin Kang,
  • Hwan Hee Yu,
  • Chang-Won Cho,
  • Young Kyung Rhee,
  • Tae-Wan Kim and
  • Young-Wook Chin

Yeast formulations such as dry yeast are essential for supplying microbial starters to the alcoholic beverage industry. In Korea, the expensive freeze-drying method is used to manufacture brewer’s dry yeast, and therefore an economical process...

  • Article
  • Open Access
3 Citations
1,699 Views
19 Pages

Optimized Liquid Medium Formulation for Sanghuangporus vaninii and Biological Activity of the Exopolysaccharides

  • Haichen Huang,
  • Xiaomin Li,
  • Qi Lu,
  • Hui Xu,
  • Huijuan Sun,
  • Junli Zhang,
  • Xiaoping Wu and
  • Junsheng Fu

8 November 2024

Aims: Sanghuangporus vaninii (S. vaninii) is a rare medicinal mushroom that is rich in polysaccharides, triterpenes, flavonoids, and other bioactive compounds. It has good potential development value. Methods and Results: We performed single factor e...

  • Article
  • Open Access
10 Citations
3,392 Views
15 Pages

This study focuses on the impact of new methods for inhibiting malolactic fermentation in white wines on their analytical and sensory properties. Enological preparations with different mechanisms of effect were tested: fumaric acid, chitosan, Estaan...

  • Article
  • Open Access
1 Citations
2,196 Views
14 Pages

Modifications of Constitutive Promoter to Large-Scale Synthesize Porcine Myoglobin in Komagataella phaffii

  • Danni Sun,
  • Yunpeng Wang,
  • Jingwen Zhou,
  • Jianghua Li,
  • Jian Chen,
  • Guocheng Du and
  • Xinrui Zhao

Myoglobin (MG) is a heme-binding protein and can be used as a color and flavor additive for artificial meat. After the selection of stable constitutive expression, although the synthesis of porcine myoglobin (pMG) was achieved through the application...

  • Article
  • Open Access
2 Citations
2,832 Views
14 Pages

Screening and Selection of a New Medium for Diosgenin Production via Microbial Biocatalysis of Fusarium sp.

  • Wancang Liu,
  • Haibo Xiang,
  • Tao Zhang,
  • Xu Pang,
  • Jing Su,
  • Hongyu Liu,
  • Baiping Ma and
  • Liyan Yu

21 April 2021

Steroidal saponins are widely used as starting precursors and medical intermediates for the semi-/total-synthesis of hundreds of steroidal drugs. One such steroidal saponin is diosgenin, which has attracted significant attention due to the huge marke...

  • Article
  • Open Access
27 Citations
5,664 Views
18 Pages

18 November 2020

Production of medium chain carboxylic acids (MCCA) as renewable feedstock bio-chemicals, from food waste (FW), requires complicated reactor configurations and supplementation of chemicals to achieve product selectivity. This study evaluated the manip...

  • Article
  • Open Access
3,233 Views
20 Pages

The biotechnological production of carotenoids offers a promising alternative to their chemical synthesis or extraction from plants. Mycolicibacterium species have shown potential as pigment-producing microorganisms. However, bacterial strains typica...

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