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135 Results Found

  • Article
  • Open Access
2 Citations
1,599 Views
20 Pages

11 October 2024

One of the most significant applications of mathematical numerical methods in biology is the theoretical description of the convectional reaction–diffusion of chemical compounds. Initial biological objects must be appropriately mimicked by digi...

  • Article
  • Open Access
8 Citations
3,088 Views
8 Pages

A synthetic phantom model is typically utilized to evaluate the initial performance of a photoacoustic image reconstruction algorithm. The characteristics of the phantom model (structural, optical, and acoustic) are required to be very similar to tho...

  • Article
  • Open Access
2 Citations
3,353 Views
18 Pages

Quantitative and objective evaluation tools are essential for assessing the performance of machine learning (ML)-based magnetic resonance imaging (MRI) reconstruction methods. However, the commonly used fidelity metrics, such as mean squared error (M...

  • Article
  • Open Access
1 Citations
3,691 Views
16 Pages

The Use of Digital Coronary Phantoms for the Validation of Arterial Geometry Reconstruction and Computation of Virtual FFR

  • Giulia Pederzani,
  • Krzysztof Czechowicz,
  • Nada Ghorab,
  • Paul D. Morris,
  • Julian P. Gunn,
  • Andrew J. Narracott,
  • David Rodney Hose and
  • Ian Halliday

11 June 2022

We present computational fluid dynamics (CFD) results of virtual fractional flow reserve (vFFR) calculations, performed on reconstructed arterial geometries derived from a digital phantom (DP). The latter provides a convenient and parsimonious descri...

  • Article
  • Open Access
6 Citations
3,466 Views
12 Pages

Generation of Digital Brain Phantom for Machine Learning Application of Dopamine Transporter Radionuclide Imaging

  • Wenyi Shao,
  • Kevin H. Leung,
  • Jingyan Xu,
  • Jennifer M. Coughlin,
  • Martin G. Pomper and
  • Yong Du

While machine learning (ML) methods may significantly improve image quality for SPECT imaging for the diagnosis and monitoring of Parkinson’s disease (PD), they require a large amount of data for training. It is often difficult to collect a lar...

  • Article
  • Open Access
6 Citations
2,994 Views
13 Pages

5 August 2023

In recent years, photoacoustic (PA) imaging has rapidly grown as a non-invasive screening technique for breast cancer detection using three-dimensional (3D) hemispherical arrays due to their large field of view. However, the development of breast ima...

  • Article
  • Open Access
1 Citations
3,238 Views
9 Pages

6 December 2022

The purpose of this study was to compare non-uniform image quality caused by the anode heel effect between two radiographic systems using a circular step-wedge (CSW) phantom and the normalized mutual information (nMI) metric. Ten repeated radiographi...

  • Article
  • Open Access
2,102 Views
17 Pages

A Novel Phantom for Standardized Microcalcification Detection Developed Using a Crystalline Growth System

  • Dee H. Wu,
  • Caroline Preskitt,
  • Natalie Stratemeier,
  • Hunter Lau,
  • Sreeja Ponnam and
  • Supriya Koya

27 February 2025

Background/Objectives: The accurate detection of microcalcifications in mammograms is critical for the early detection of breast cancer. However, the variability between different manufacturers is significant, particularly with digital breast tomosyn...

  • Article
  • Open Access
1 Citations
2,527 Views
16 Pages

A Novel Method to Model Image Creation Based on Mammographic Sensors Performance Parameters: A Theoretical Study

  • Nektarios Kalyvas,
  • Anastasia Chamogeorgaki,
  • Christos Michail,
  • Aikaterini Skouroliakou,
  • Panagiotis Liaparinos,
  • Ioannis Valais,
  • George Fountos and
  • Ioannis Kandarakis

20 February 2023

Background: Mammographic digital imaging is based on X-ray sensors with solid image quality characteristics. These primarily include (a) a response curve that yields high contrast and image latitude, (b) a frequency response given by the Modulation T...

  • Article
  • Open Access
10 Citations
6,283 Views
10 Pages

Proper Management of the Clinical Exposure Index Based on Body Thickness Using Dose Optimization Tools in Digital Chest Radiography: A Phantom Study

  • Yongsu Yoon,
  • Hyemin Park,
  • Jungmin Kim,
  • Jungsu Kim,
  • Younghoon Roh,
  • Nobukazu Tanaka and
  • Junji Morishita

In radiography, the exposure index (EI), as per the International Electrotechnical Commission standard, depends on the incident beam quality and exposure dose to the digital radiography system. Today automatic exposure control (AEC) systems are commo...

  • Article
  • Open Access
1 Citations
2,533 Views
15 Pages

Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy

  • Ji-Won Choi,
  • Ji-Young Choi,
  • Hanil Jang,
  • Kyung-Kwang Joo and
  • Byoung-Chan Kim

28 June 2022

We synthesized an alcohol-based liquid scintillator (AbLS), and we implemented an auxiliary monitoring system with short calibration intervals using AbLS for particle therapy. The commercial liquid scintillator used in previous studies did not allow...

  • Article
  • Open Access
7 Citations
3,498 Views
16 Pages

Incorporating Robustness to Imaging Physics into Radiomic Feature Selection for Breast Cancer Risk Estimation

  • Raymond J. Acciavatti,
  • Eric A. Cohen,
  • Omid Haji Maghsoudi,
  • Aimilia Gastounioti,
  • Lauren Pantalone,
  • Meng-Kang Hsieh,
  • Emily F. Conant,
  • Christopher G. Scott,
  • Stacey J. Winham and
  • Despina Kontos
  • + 3 authors

1 November 2021

Digital mammography has seen an explosion in the number of radiomic features used for risk-assessment modeling. However, having more features is not necessarily beneficial, as some features may be overly sensitive to imaging physics (contrast, noise,...

  • Article
  • Open Access
56 Citations
9,993 Views
19 Pages

7 August 2020

In recent years, the use of unmanned aerial vehicles (UAVs) has received increasing attention in remote sensing, vegetation monitoring, vegetation index (VI) mapping, precision agriculture, etc. It has many advantages, such as high spatial resolution...

  • Article
  • Open Access
4 Citations
3,426 Views
18 Pages

Evaluating the Quality of Patient-Specific Deformable Image Registration in Adaptive Radiotherapy Using a Digitally Enhanced Head and Neck Phantom

  • Elisabetta Cagni,
  • Andrea Botti,
  • Matteo Orlandi,
  • Marco Galaverni,
  • Cinzia Iotti,
  • Mauro Iori,
  • Geraint Lewis and
  • Emiliano Spezi

22 September 2022

Despite the availability of national and international guidelines, an accurate and efficient, patient-specific, deformable image registration (DIR) validation methodology is not yet established, and several groups have found an incompatibility of the...

  • Article
  • Open Access
18 Citations
5,265 Views
22 Pages

Realistic 3D Phantoms for Validation of Microwave Sensing in Health Monitoring Applications

  • Mariella Särestöniemi,
  • Daljeet Singh,
  • Rakshita Dessai,
  • Charline Heredia,
  • Sami Myllymäki and
  • Teemu Myllylä

20 March 2024

The development of new medical-monitoring applications requires precise modeling of effects on the human body as well as the simulation and the emulation of realistic scenarios and conditions. The first aim of this paper is to develop realistic and a...

  • Article
  • Open Access
102 Citations
14,219 Views
21 Pages

8 September 2020

Unmanned Aerial Vehicles (UAVs) have revolutionised the availability of high resolution topographic data in many disciplines due to their relatively low-cost and ease of deployment. Consumer-grade Real Time Kinematic Global Navigation Satellite Syste...

  • Article
  • Open Access
3 Citations
4,624 Views
23 Pages

Main Uncertainties in the RF Ultrasound Scanning Simulation of the Standard Ultrasound Phantoms

  • Monika Makūnaitė,
  • Rytis Jurkonis,
  • Arūnas Lukoševičius and
  • Mindaugas Baranauskas

28 June 2021

Ultrasound echoscopy technologies are continuously evolving towards new modalities including quantitative parameter imaging, elastography, 3D scanning, and others. The development and analysis of new methods and algorithms require an adequate digital...

  • Article
  • Open Access
5 Citations
5,461 Views
11 Pages

25 April 2021

Anode heel effects are known to cause non-uniform image quality, but no method has been proposed to evaluate the non-uniform image quality caused by the heel effect. Therefore, the purpose of this study was to evaluate non-uniform image quality in di...

  • Article
  • Open Access
6 Citations
3,509 Views
14 Pages

Low-complexity ultrasound systems are increasingly desired for both wearable, point-of-care ultrasound and high-end massive-channel ultrasound for 3-D matrix imaging. However, the imaging capabilities, including spatial resolution and contrast, could...

  • Article
  • Open Access
7 Citations
3,566 Views
17 Pages

Accurate and Fast Deep Learning Dose Prediction for a Preclinical Microbeam Radiation Therapy Study Using Low-Statistics Monte Carlo Simulations

  • Florian Mentzel,
  • Jason Paino,
  • Micah Barnes,
  • Matthew Cameron,
  • Stéphanie Corde,
  • Elette Engels,
  • Kevin Kröninger,
  • Michael Lerch,
  • Olaf Nackenhorst and
  • Susanna Guatelli
  • + 6 authors

4 April 2023

Microbeam radiation therapy (MRT) utilizes coplanar synchrotron radiation beamlets and is a proposed treatment approach for several tumor diagnoses that currently have poor clinical treatment outcomes, such as gliosarcomas. Monte Carlo (MC) simulatio...

  • Article
  • Open Access
23 Citations
3,530 Views
14 Pages

23 October 2020

Although conventional denoising filters have been developed for noise reduction from digital images, these filters simultaneously cause blurring in the images. To address this problem, we proposed the fast non-local means (FNLM) denoising algorithm w...

  • Article
  • Open Access
322 Views
11 Pages

Chest Radiography Optimization: Identifying the Optimal kV for Image Quality in a Phantom Study

  • Ioannis Antonakos,
  • Kyriakos Kokkinogoulis,
  • Maria Giannopoulou and
  • Efstathios P. Efstathopoulos

21 January 2026

Chest radiography remains one of the most frequently performed imaging examinations, highlighting the need for optimization of acquisition parameters to balance image quality and radiation dose. This study presents a phantom-based quantitative evalua...

  • Article
  • Open Access
6 Citations
3,475 Views
20 Pages

Exploring Microphone Technologies for Digital Auscultation Devices

  • Matteo Zauli,
  • Lorenzo Mistral Peppi,
  • Luca Di Bonaventura,
  • Valerio Antonio Arcobelli,
  • Alberto Spadotto,
  • Igor Diemberger,
  • Valerio Coppola,
  • Sabato Mellone and
  • Luca De Marchi

12 November 2023

The aim of this work is to present a preliminary study for the design of a digital auscultation system, i.e., a novel wearable device for patient chest auscultation and a digital stethoscope. The development and testing of the electronic stethoscope...

  • Article
  • Open Access
15 Citations
7,987 Views
18 Pages

A Parametric EIT System Spice Simulation with Phantom Equivalent Circuits

  • Christos Dimas,
  • Nikolaos Uzunoglu and
  • Paul Peter Sotiriadis

In this paper a number of LT Spice simulations have been carried out on an Electrical Impedance Tomography (EIT) system, which includes the whole analog and digital circuitry as well as the subject to be examined (phantom model). The aim of this stud...

  • Data Descriptor
  • Open Access
4 Citations
3,068 Views
10 Pages

16 August 2022

The World Health Organization indicates the top cause of death is heart disease. These diseases can be detected using several imaging modalities, especially cardiac computed tomography (CT), whose images have imperfections associated with noise and c...

  • Article
  • Open Access
2 Citations
2,214 Views
16 Pages

Qualitative and Quantitative Evaluation of a Deep Learning-Based Reconstruction for Accelerated Cardiac Cine Imaging

  • Junjie Ma,
  • Xucheng Zhu,
  • Suryanarayanan Kaushik,
  • Eman Ali,
  • Liangliang Li,
  • Kavitha Manickam,
  • Ke Li and
  • Martin A. Janich

Two-dimensional (2D) cine imaging is essential in routine clinical cardiac MR (CMR) exams for assessing cardiac structure and function. Traditional cine imaging requires patients to hold their breath for extended periods and maintain consistent heart...

  • Article
  • Open Access
6 Citations
3,394 Views
13 Pages

Currently, breast cancer is the most commonly diagnosed type of cancer worldwide. Digital Breast Tomosynthesis (DBT) has been widely accepted as a stand-alone modality to replace Digital Mammography, particularly in denser breasts. However, the image...

  • Proceeding Paper
  • Open Access
3 Citations
3,226 Views
6 Pages

FPGA Implementation of ECG Signal Processing for Use in a Neonatal Heart Rate Monitoring System

  • Henry Dore,
  • Rodrigo Aviles-Espinosa and
  • Elizabeth Rendon-Morales

1 November 2022

A field-programmable gate array (FPGA) based system for digital filtering in a neonatal heart rate monitoring system is presented. The system employs electric potential sensors (EPS) and contains a single hardware filter stage for antialiasing. The r...

  • Article
  • Open Access
5 Citations
10,315 Views
10 Pages

Detecting Breast Cancer with a Dual-Modality Device

  • Kamila Padia,
  • Tania S. Douglas,
  • Lydia L. Cairncross,
  • Roland V. Baasch and
  • Christopher L. Vaughan

Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography...

  • Article
  • Open Access
1,824 Views
16 Pages

Safety Assessment of Microwave Breast Imaging: Heating Analysis on Digital Breast Phantoms

  • Alessandra Ronca,
  • Luca Zilberti,
  • Oriano Bottauscio,
  • Gianluigi Tiberi and
  • Alessandro Arduino

12 April 2025

The impact of breast cancer on public health is serious, and due to risk/benefit assessment, screening programs are usually restricted to women older than 49 years. Microwave imaging devices offer advantages such as non-ionizing radiation, low cost,...

  • Article
  • Open Access
3 Citations
3,978 Views
17 Pages

13 March 2024

Auscultation is a fundamental diagnostic technique that provides valuable diagnostic information about different parts of the body. With the increasing prevalence of digital stethoscopes and telehealth applications, there is a growing trend towards d...

  • Article
  • Open Access
3 Citations
7,286 Views
11 Pages

The Effects of Body Position on Pelvic Tilt Angles Measured with a Smartphone-Based Navigated Ultrasound System in Symptom-Free Young Adults

  • Carlos Marques,
  • Tobias Martin,
  • Franziska Fiedler,
  • Mathias Weber,
  • Frank Lampe,
  • Viktor Breul and
  • Josef Kozak

The study aimed to investigate whether pelvic tilt (PT) angles differ between the supine and upright position in symptom-free young adults. Additionally, the concurrent validity of the measurement system was tested on a pelvis phantom against a digit...

  • Proceeding Paper
  • Open Access
1 Citations
2,100 Views
5 Pages

Respiratory Inductive Plethysmography System for Knitted Helical Coils

  • Kevin Kiener,
  • Aishwarya Anand,
  • William Fobelets and
  • Kristel Fobelets

Three-dimensional knitted helical coils are very sensitive inductive sensors that can be used to monitor breathing. Their inductance is high and the quality factor relatively low. A read-out circuit is designed and tested to track the inductance vari...

  • Article
  • Open Access
12 Citations
4,483 Views
21 Pages

13 February 2021

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in the clinical setting, enhancing the quality...

  • Article
  • Open Access
5 Citations
1,120 Views
20 Pages

Assessment of the Mechanical Properties of Soft Tissue Phantoms Using Impact Analysis

  • Arthur Bouffandeau,
  • Anne-Sophie Poudrel,
  • Chloé Brossier,
  • Giuseppe Rosi,
  • Vu-Hieu Nguyen,
  • Charles-Henri Flouzat-Lachaniette,
  • Jean-Paul Meningaud and
  • Guillaume Haïat

22 February 2025

Skin physiopathological conditions have a strong influence on its biomechanical properties. However, it remains difficult to accurately assess the surface stiffness of soft tissues. The aim of this study was to evaluate the performances of an impact-...

  • Article
  • Open Access
36 Citations
6,879 Views
15 Pages

Portable Ultrasound Research System for Use in Automated Bladder Monitoring with Machine-Learning-Based Segmentation

  • Marc Fournelle,
  • Tobias Grün,
  • Daniel Speicher,
  • Steffen Weber,
  • Mehmet Yilmaz,
  • Dominik Schoeb,
  • Arkadiusz Miernik,
  • Gerd Reis,
  • Steffen Tretbar and
  • Holger Hewener

28 September 2021

We developed a new mobile ultrasound device for long-term and automated bladder monitoring without user interaction consisting of 32 transmit and receive electronics as well as a 32-element phased array 3 MHz transducer. The device architecture is ba...

  • Article
  • Open Access
4,205 Views
16 Pages

Optimization of Breast Tomosynthesis Visualization through 3D Volume Rendering

  • Ana M. Mota,
  • Matthew J. Clarkson,
  • Pedro Almeida and
  • Nuno Matela

3D volume rendering may represent a complementary option in the visualization of Digital Breast Tomosynthesis (DBT) examinations by providing an understanding of the underlying data at once. Rendering parameters directly influence the quality of rend...

  • Article
  • Open Access
8 Citations
3,266 Views
9 Pages

Simulation and Training of Needle Puncture Procedure with a Patient-Specific 3D Printed Gluteal Artery Model

  • Paweł Rynio,
  • Aleksander Falkowski,
  • Jan Witowski,
  • Arkadiusz Kazimierczak,
  • Łukasz Wójcik and
  • Piotr Gutowski

The puncture of the gluteal artery (GA) is a rare and difficult procedure. Less experienced clinicians do not always have the opportunity to practice and prepare for it, which creates a need for novel training tools. We aimed to investigate the feasi...

  • Article
  • Open Access
12 Citations
3,487 Views
18 Pages

14 February 2022

In this study, we evaluated the improvement of image quality in digital breast tomosynthesis under low-radiation dose conditions of pre-reconstruction processing using conditional generative adversarial networks [cGAN (pix2pix)]. Pix2pix pre-reconstr...

  • Article
  • Open Access
155 Citations
11,310 Views
16 Pages

Low-Cost UAV for High-Resolution and Large-Scale Coastal Dune Change Monitoring Using Photogrammetry

  • Quentin Laporte-Fauret,
  • Vincent Marieu,
  • Bruno Castelle,
  • Richard Michalet,
  • Stéphane Bujan and
  • David Rosebery

In this paper, coastal dune data are collected at Truc Vert, SW France, using photogrammetry via Unmanned Aerial Vehicles (UAVs). A low-cost GoPro-equipped DJI Phantom 2 quadcopter and a 20 MPix camera-equipped DJI Phantom 4 Pro quadcopter UAVs were...

  • Article
  • Open Access
4 Citations
5,443 Views
14 Pages

11 October 2018

In this paper we propose a novel method for tracking the respiratory phase and 3D tumor position in real time during treatment. The method uses planning four-dimensional (4D) computed tomography (CT) obtained through the respiratory phase, and a kV p...

  • Article
  • Open Access
1,401 Views
23 Pages

This study compares the mapping accuracy of a non-RTK ultra-lightweight drone (DJI Mini2) with two survey-grade RTK-enabled drones (DJI Mavic3E and Phantom4) in three different sites. Flight parameters and weather conditions were the same on each sit...

  • Article
  • Open Access
24 Citations
8,292 Views
14 Pages

Unmanned Aerial Vehicles (UAVs) also known as drones have created many challenges to the digital forensic field. These challenges are introduced in all processes of the digital forensic investigation (i.e., identification, preservation, examination,...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,402 Views
15 Pages

17 August 2021

Background: Time-of-Flight (TOF) is a leading technological development of Positron Emission Tomography (PET) scanners. It reduces noise at the Maximum-Likelihood solution, depending on the coincidence–timing–resolution (CTR). However, in clinical ap...

  • Article
  • Open Access
18 Citations
6,357 Views
18 Pages

Time-Domain Functional Diffuse Optical Tomography System Based on Fiber-Free Silicon Photomultipliers

  • Andrea Farina,
  • Susanna Tagliabue,
  • Laura Di Sieno,
  • Edoardo Martinenghi,
  • Turgut Durduran,
  • Simon Arridge,
  • Fabrizio Martelli,
  • Alessandro Torricelli,
  • Antonio Pifferi and
  • Alberto Dalla Mora

29 November 2017

Based on recent developments in both single-photon detectors and timing electronic circuits, we designed a compact and cost effective time-domain diffuse optical tomography system operated at 1 Hz acquisition rate, based on eight silicon photomultipl...

  • Article
  • Open Access
18 Citations
5,308 Views
17 Pages

19 January 2021

Unmanned aerial vehicles (UAV) have long been well established as a reliable way to construct highly accurate, up-to-date digital elevation models (DEM). However, the territories which were modeled by the results of UAV surveys can be characterized a...

  • Article
  • Open Access
13 Citations
3,214 Views
20 Pages

6 September 2021

In this study, a novel combination of hybrid generative adversarial networks (GANs) comprising cycle-consistent GAN, pix2pix, and (mask pyramid network) MPN (CGpM-metal artifact reduction [MAR]), was developed using projection data to reduce metal ar...

  • Article
  • Open Access
5 Citations
4,684 Views
12 Pages

A Novel Markerless Lung Tumor-Tracking Method Using Treatment MV Beam Imaging

  • Timothy Rozario,
  • Tsuicheng D. Chiu,
  • Mingli Chen,
  • Xun Jia,
  • Weiguo Lu,
  • Sergey Bereg and
  • Weihua Mao

6 December 2018

A novel method was developed to track lung tumor motion in real time during radiation therapy with the purpose to allow target radiation dose escalation while simultaneously reducing the dose to sensitive structures, thereby increasing local control...

  • Article
  • Open Access
30 Citations
11,169 Views
12 Pages

Design and Implementation of a New Wireless Carotid Neckband Doppler System with Wearable Ultrasound Sensors: Preliminary Results

  • Ilseob Song,
  • Jongmin Yoon,
  • Jinbum Kang,
  • Min Kim,
  • Won Seuk Jang,
  • Na-Young Shin and
  • Yangmo Yoo

29 May 2019

Noninvasive monitoring of blood flow in the carotid artery is important for evaluating not only cerebrovascular but also cardiovascular diseases. In this paper, a wireless neckband ultrasound Doppler system, in which two 2.5-MHz ultrasonic sensors ar...

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