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2,515 Results Found

  • Article
  • Open Access
2 Citations
2,477 Views
10 Pages

6 November 2020

The cyclic stress response behavior of Ti-3Al-8V-6Cr-4Mo-4Zr alloy with three different microstructures has been systematically studied. The cyclic stress response was highly related to the applied strain amplitude and precipitated phase. At low stra...

  • Article
  • Open Access
114 Citations
6,627 Views
22 Pages

Cyclic Response of Steel Fiber Reinforced Concrete Slender Beams: An Experimental Study

  • Constantin E. Chalioris,
  • Parthena-Maria K. Kosmidou and
  • Chris G. Karayannis

29 April 2019

Reinforced concrete (RC) beams under cyclic loading usually suffer from reduced aggregate interlock and eventually weakened concrete compression zone due to severe cracking and the brittle nature of compressive failure. On the other hand, the additio...

  • Article
  • Open Access
1 Citations
2,614 Views
15 Pages

17 November 2022

Oxygen plays important roles in regulating various biological activities under physiological and pathological conditions. However, the response of cells facing temporal variation in oxygen microenvironments has seldom been studied due to technical li...

  • Article
  • Open Access
2 Citations
1,541 Views
18 Pages

Adjacent cyclic explosions significantly impact the stability of underground anchored caverns. Based on the similar model test of the vault explosion of the anchored cavern, the dynamic analysis finite element software ANSYS/LSDYNA(18.0) was used to...

  • Article
  • Open Access
1 Citations
864 Views
23 Pages

12 September 2025

Dynamic fatigue of rocks under repeated cyclic impact is a nonconservative property, as surrounding rocks in real environments subjects them to variable impact disturbances, and the degree of damage varies under different energy level loads. To evalu...

  • Article
  • Open Access
8 Citations
2,655 Views
17 Pages

The shear behavior and dynamic response of a steel–silt interface are significant for the safety and stability of offshore structures in the Yellow River Delta. A series of steel–silt interface cyclic shear tests under constant normal loa...

  • Review
  • Open Access
31 Citations
9,399 Views
27 Pages

Bacillus cyclic lipopeptides (CLP), part of the three main families—surfactins, iturins, and fengycins—are secondary metabolites with a unique chemical structure that includes both peptide and lipid components. Being amphiphilic compounds...

  • Article
  • Open Access
14 Citations
3,302 Views
22 Pages

2 September 2022

The shape and internal dynamic response characteristics of the plastic zone near the fatigue crack tip region, especially the cyclic plastic zone (CPZ), are the main factors affecting the fatigue crack initiation and propagation behaviors of ductile...

  • Article
  • Open Access
1 Citations
1,827 Views
13 Pages

15 November 2024

Cyclic polymers have many interesting properties compared to their linear analogs, but there are very few examples of their synthesis. This is because most cyclic polymers have been synthesized by stepwise processes, including synthesizing homo- or h...

  • Communication
  • Open Access
4 Citations
2,213 Views
9 Pages

17 September 2021

Smart hollow polymeric microspheres have been widely applied in various fields such as controlled release, drug delivery, catalysis, and so on. Herein, a facile, green and one-step template-free method is introduced for preparing pH-responsive hollow...

  • Article
  • Open Access
1,008 Views
12 Pages

Response Analysis of PLC Optical Splitters Under Force Cyclic Loading

  • Lianqiong Jiang,
  • Yu Zheng,
  • Ke Zeng and
  • Xin Tang

10 April 2025

In order to better understand the damage phenomenon and failure mechanism of planar lightwave circuit (PLC) optical splitters under force cycling, this paper established an online test experimental platform to study their optical and mechanical perfo...

  • Article
  • Open Access
17 Citations
5,464 Views
18 Pages

26 June 2020

Efforts to isolate a broad-spectrum antimicrobial peptide (AMP) from microbial sources have been on the rise recently. Here, we report the identification, the optimization of the culture conditions, and the characterization of an efficient AMP from t...

  • Article
  • Open Access
4 Citations
3,159 Views
21 Pages

Systems Biology Analysis of Temporal Dynamics That Govern Endothelial Response to Cyclic Stretch

  • Michael W. Lai,
  • Nathan Chow,
  • Antonio Checco,
  • Balvir Kunar,
  • David Redmond,
  • Shahin Rafii and
  • Sina Y. Rabbany

8 December 2022

Endothelial cells in vivo are subjected to a wide array of mechanical stimuli, such as cyclic stretch. Notably, a 10% stretch is associated with an atheroprotective endothelial phenotype, while a 20% stretch is associated with an atheroprone endothel...

  • Article
  • Open Access
62 Citations
8,353 Views
12 Pages

3 February 2014

The mechanical behavior of the adhesive interface between the fiber-reinforced polymer (FRP) strip and the concrete substrate often controls the response of FRP-strengthened reinforced concrete (RC) members. Plenty of studies devoted to understanding...

  • Article
  • Open Access
12 Citations
4,247 Views
21 Pages

28 October 2021

This paper presents cyclic behaviour of bolted and hybrid–combined bolted and bonded fibre reinforced polymer (FRP) beam-to-column joints between I-shaped members using steel and FRP cleats. Five full-scale cyclic tests are carried out to study momen...

  • Article
  • Open Access
13 Citations
4,571 Views
19 Pages

Dynamic Response of Offshore Open-Ended Pile under Lateral Cyclic Loadings

  • Junwei Liu,
  • Zhen Guo,
  • Na Zhu,
  • Hui Zhao,
  • Ankit Garg,
  • Longfei Xu,
  • Tao Liu and
  • Changchun Fu

Foundations for offshore wind turbines (OWTs) are mainly open-ended piles that are subjected to cyclic loadings caused by winds, waves and currents. This study aims to investigate the dynamic responses of open-ended pipe pile under lateral cyclic loa...

  • Article
  • Open Access
12 Citations
1,893 Views
26 Pages

Precursors of Cyclic Loading and Unloading Sandstone Failure Based on “Acoustic-Thermal” Loading–Unloading Response Ratio

  • Hao Xu,
  • Liqiang Ma,
  • Kewang Cao,
  • Naseer Muhammad Khan,
  • Sajjad Hussain,
  • Dongdong Niu,
  • Saad S. Alarifi and
  • Sher Bacha

26 June 2023

Coal mining often causes periodic disruption in the rock mass around the stope. The study of the deformation and failure characteristics of cyclic loading and unloading sandstone is very critical for gaining a thorough understanding of the mechanisms...

  • Article
  • Open Access
4 Citations
2,183 Views
18 Pages

Mechanical and Acoustic Response of Low-Permeability Sandstone under Multilevel Cyclic Loading-Unloading Stress Paths

  • Hongying Tan,
  • Hejuan Liu,
  • Xilin Shi,
  • Hongling Ma,
  • Xiaosong Qiu,
  • Yintong Guo and
  • Shengnan Ban

26 September 2023

Low-permeability sandstone reservoirs have been widely used as a gas storage medium worldwide. Compared with the high porosity and high permeability of sandstone, low-permeability sandstone may present different mechanical (deformation, damage or fai...

  • Article
  • Open Access
1,550 Views
25 Pages

9 December 2024

Extreme marine environmental cyclic loading significantly affects the serviceability of monopiles applied for the foundation of offshore wind turbines (OWTs). Existing research has primarily used p-y methods or total stress-based models to investigat...

  • Article
  • Open Access
3 Citations
3,386 Views
15 Pages

A Simplified Calculation Method for Cyclic Response of Laterally Loaded Piles Based on Strain Wedge Model in Soft Clay

  • Xin Liu,
  • Zhongyuan Yao,
  • Wenbo Zhu,
  • Yu Zhang,
  • Shu Yan,
  • Xiaojiang Guo and
  • Guoliang Dai

2 November 2022

This paper proposed a simplified calculation method to analyze the cyclic response of large-diameter single piles based on the modified strain wedge model. Firstly, the pile–soft clay interaction above the pile-rotating point is represented by...

  • Article
  • Open Access
16 Citations
2,885 Views
17 Pages

30 April 2022

Natural granular materials widely used in building and infrastructure development consume a considerable number of natural resources. To avoid depleting natural granular materials, recycled concrete aggregates (RCA) from construction and demolition w...

  • Article
  • Open Access
207 Views
28 Pages

This study investigates the cyclic behaviour of demountable steel–concrete composite extended end-plate reduced web section (RWS) connections for the first time, aiming to facilitate post-seismic beam replacement. A validated high-fidelity fini...

  • Article
  • Open Access
22 Citations
5,773 Views
28 Pages

18 April 2020

The 2008 Wenchuan-China earthquake showed the importance of considering the bidirectional seismic action as a cause of failure in column hinge mechanisms. Subsequently, the large 2011 Tohoku-Japan earthquake revealed that Special Moment Frames buildi...

  • Article
  • Open Access
1 Citations
2,086 Views
28 Pages

10 February 2024

A cyclic plasticity constitutive model was developed for materials with asymmetric cyclic behavior to explain the stabilized stress–strain response under variable amplitude loading. The proposed constitutive model incorporated the von Mises yie...

  • Article
  • Open Access
8 Citations
2,799 Views
12 Pages

4 August 2022

Based on the twin bridge shear specimen, the cyclic shear experiments were performed on 1.2 mm thin plates of 316L metastable austenitic stainless steel with different strain amplitudes from 1 to 5% at ambient temperature. The fatigue behavior of 316...

  • Article
  • Open Access
10 Citations
2,676 Views
21 Pages

18 November 2020

Past earthquakes demonstrate that non-structural elements could be vulnerable to a relatively low intensity ground shaking which induces negligible structural damage. The study aims to improve previously developed macro-models of cold-formed steel (C...

  • Article
  • Open Access
8 Citations
3,709 Views
29 Pages

Assessing Effectiveness of Shape Memory Alloys on the Response of Bolted T-Stub Connections Subjected to Cyclic Loading

  • Ahmadreza Torabipour,
  • Nima Asghari,
  • Homa Haghighi,
  • Shaghayegh Yaghoubi and
  • Girum Urgessa

30 January 2023

This study presents finite element analysis of double split tee (DST) connections with high-strength steel bolts and coupled split tee sections, to evaluate various cyclic response parameters and elements. The investigation included quantifying conne...

  • Article
  • Open Access
749 Views
16 Pages

13 July 2025

This paper primarily investigates the response and failure behavior of 6063-T5 aluminum alloy square tubes with varying outer side lengths under symmetric curvature-controlled cyclic bending in different bending directions. The response is characteri...

  • Article
  • Open Access
6 Citations
3,456 Views
15 Pages

26 November 2020

Cyclic response and fatigue behavior are sensitive to the microstructure of material induced by heat treatment. In this paper, three sets of high-temperature superalloy Inconel 718 with different heat treatment, namely annealed, aged, and directly ag...

  • Article
  • Open Access
10 Citations
3,396 Views
17 Pages

In the process of geotechnical engineering excavation, wet and water-filled rock masses are inevitable. To obtain the mechanical properties of these rocks, indoor tests are required, and most of the rock tests rock tests are dry or nearly dry. They c...

  • Article
  • Open Access
16 Citations
3,652 Views
20 Pages

27 July 2019

The response ranges of three principal mechanical parameters were measured following cyclic compressive loading of three types of concrete specimen to a pre-defined number of cycles. Thus, compressive strength, compressive modulus of elasticity, and...

  • Article
  • Open Access
15 Citations
4,284 Views
17 Pages

15 February 2017

In this paper, the synergistic effects of stress rupture and cyclic loading on the strain response of fiber-reinforced ceramic-matrix composites (CMCs) at elevated temperature in air have been investigated. The stress-strain relationships considering...

  • Article
  • Open Access
6 Citations
4,512 Views
9 Pages

11 June 2019

Mouse Leydig Tumor cells (mLTC), transiently expressing cAMP-dependent luciferase, were used to study the influence of sexual steroids and of adiponectin (ADPN) on the cAMP response to luteinizing hormones (LH). While testosterone and progesterone ha...

  • Article
  • Open Access
4 Citations
2,832 Views
21 Pages

24 July 2023

The inelastic response of reinforced concrete (RC) frames under seismic loading is influenced by mechanical and geometrical properties and by the reinforcement arrangement of the beam–column members. In this paper, the seismic response and rece...

  • Article
  • Open Access
7 Citations
3,973 Views
14 Pages

Evolution Prediction of Hysteresis Behavior of Sand under Cyclic Loading

  • Pingxin Xia,
  • Longtan Shao,
  • Wen Deng and
  • Chao Zeng

29 April 2022

Soil cyclic degradation is a serious issue that should be considered in engineering design and maintenance. The hysteretic response causes strength degradation and excessive settlement of soil structure in engineered and natural geosystems. Hysteresi...

  • Article
  • Open Access
7 Citations
3,342 Views
12 Pages

19 October 2022

This paper investigates the fatigue cyclic deformation behavior of mid-carbon steel. Uniaxial tensile loading tests and fatigue tests under constant and multi-step amplitude loading steps are performed to characterize the influence of loading history...

  • Article
  • Open Access
1,433 Views
11 Pages

24 June 2024

This paper aims to investigate the response and fracture of EMT carbon steel round-hole tubes (EMT carbon steel RHTs) under cyclic bending loads. The study considers four different hole orientations (0°, 30°, 60°, and 90°) and five di...

  • Article
  • Open Access
14 Citations
4,438 Views
23 Pages

Cyclic Tetra-Adenylate (cA4) Recognition by Csa3; Implications for an Integrated Class 1 CRISPR-Cas Immune Response in Saccharolobus solfataricus

  • Alexander A. Charbonneau,
  • Debra M. Eckert,
  • Colin C. Gauvin,
  • Nathanael G. Lintner and
  • C. Martin Lawrence

9 December 2021

Csa3 family transcription factors are ancillary CRISPR-associated proteins composed of N-terminal CARF domains and C-terminal winged helix-turn-helix domains. The activity of Csa3 transcription factors is thought to be controlled by cyclic oligoadeny...

  • Article
  • Open Access
20 Citations
7,891 Views
12 Pages

24 April 2012

NW-G01, produced by Streptomyces alboflavus 313, is a novel cyclic hexapeptide antibiotic with many potential applications, including antimicrobial activity and antitumor agents. This study developed a system for optimizing medium components in order...

  • Article
  • Open Access
80 Citations
4,596 Views
30 Pages

Effect of Steel Fibers on the Hysteretic Performance of Concrete Beams with Steel Reinforcement—Tests and Analysis

  • Violetta K. Kytinou,
  • Constantin E. Chalioris,
  • Chris G. Karayannis and
  • Anaxagoras Elenas

29 June 2020

The use of fibers as mass reinforcement to delay cracking and to improve the strength and the post-cracking performance of reinforced concrete (RC) beams has been well documented. However, issues of common engineering practice about the beneficial ef...

  • Article
  • Open Access
13 Citations
6,973 Views
21 Pages

3 June 2017

Simulation of a large number of deformable bodies is often difficult because complex high-level modeling is required to address both multi-body contact and viscoelastic deformation. This necessitates the combined use of a discrete element method (DEM...

  • Article
  • Open Access
13 Citations
4,246 Views
11 Pages

15 April 2019

The storage and utilization of waste heat in low and medium temperature ranges using phase change materials (PCMs) is an effective technology to improve energy utilization efficiency in combined cooling, heating, and power (CCHP) systems. In this pap...

  • Article
  • Open Access
22 Citations
5,778 Views
21 Pages

Validation of a Modal Work Approach for Forced Response Analysis of Bladed Disks

  • Lorenzo Pinelli,
  • Francesco Lori,
  • Michele Marconcini,
  • Roberto Pacciani and
  • Andrea Arnone

11 June 2021

The paper describes a numerical method based on a modal work approach to evaluate the forced response of bladed disks and its validation against numerical results obtained by a commercial FEM code. Forcing functions caused by rotor–stator interaction...

  • Article
  • Open Access
15 Citations
4,411 Views
22 Pages

25 July 2022

The corrosion of steel reinforcement negatively influences the mechanical performance of reinforced concrete (RC) elements reducing both their strength capacity and ductility. Especially in seismic prone areas, the degradation of the cyclic behavior...

  • Article
  • Open Access
1 Citations
2,322 Views
23 Pages

Influence of Exogenous Neuropeptides on the Astrocyte Response Under Conditions of Continuous and Cyclic Hypoxia and Red Blood Cell Lysate

  • Klaudyna Kojder,
  • Magdalena Gąssowska-Dobrowolska,
  • Wojciech Żwierełło,
  • Patrycja Kłos,
  • Katarzyna Piotrowska,
  • Agata Wszołek,
  • Agnieszka Maruszewska,
  • Izabela Gutowska,
  • Dariusz Chlubek and
  • Irena Baranowska-Bosiacka

Acute brain injury includes different pathologies: stroke, traumatic injury, subarachnoidale haemorhhage. In the pathophysiology of acute brain injury, secondary injury with hyperactivation of glia plays a crucial role. Activated glial cells induce p...

  • Article
  • Open Access
1 Citations
3,120 Views
23 Pages

ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines

  • Petr Daniel,
  • Kamila Balušíková,
  • Radka Václavíková,
  • Karolína Šeborová,
  • Šárka Ransdorfová,
  • Marie Valeriánová,
  • Longfei Wei,
  • Michael Jelínek,
  • Tereza Tlapáková and
  • Jan Kovář
  • + 4 authors

23 January 2023

A limited number of studies are devoted to regulating TRIP6 expression in cancer. Hence, we aimed to unveil the regulation of TRIP6 expression in MCF-7 breast cancer cells (with high TRIP6 expression) and taxane-resistant MCF-7 sublines (manifesting...

  • Article
  • Open Access
511 Views
15 Pages

21 October 2025

Reinforced soil retaining walls (RSWs) for railways are key subgrade structures that bear cyclic loads from trains, and their long-term durability directly affects railway operation safety. The mechanical behavior of RSWs under cyclic loading has bee...

  • Article
  • Open Access
5 Citations
2,585 Views
17 Pages

21 November 2019

The ratcheting behavior of a steel pipe with assembly parts was examined under internal pressure and a cyclic bending load, which has not been seen in previous research. An experimentally validated and three dimensional (3D) elastic-plastic finite el...

  • Feature Paper
  • Article
  • Open Access
2 Citations
3,245 Views
14 Pages

Real Cyclic Load-Bearing Test of a Ceramic-Reinforced Slab

  • Albert Albareda-Valls,
  • Alicia Rivera-Rogel,
  • Ignacio Costales-Calvo and
  • David García-Carrera

4 March 2020

Ceramic-reinforced slabs were widely used in Spain during the second half of the 20th century, especially for industrial buildings. This solution was popular due to the lack of materials at that time, as it requires almost no concrete and low ratios...

  • Article
  • Open Access
34 Citations
12,006 Views
20 Pages

11 February 2014

In this paper, the superelastic shape memory alloy (SMA) slit damper system as an alternative design approach for steel structures is intended to be evaluated with respect to inelastic behavior simulated by refined finite element (FE) analyses. Altho...

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