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148 Results Found

  • Article
  • Open Access
8 Citations
2,870 Views
11 Pages

21 September 2022

This paper is focused on the issue of preparing the cutting edge microgeometry of cutting inserts made of cubic boron nitride (CBN). The aim of this research was to investigate the possibilities of rotary ultrasonic machining (RUM) for preparing asym...

  • Article
  • Open Access
23 Citations
3,413 Views
14 Pages

Estimation of Drag Finishing Abrasive Effect for Cutting Edge Preparation in Broaching Tool

  • Cristian F. Pérez-Salinas,
  • Ander del Olmo and
  • L. Norberto López de Lacalle

24 July 2022

In recent years, cutting edge preparation became a topic of high interest in the manufacturing industry because of the important role it plays in the performance of the cutting tool. This paper describes the use of the drag finishing DF cutting edge...

  • Article
  • Open Access
15 Citations
2,702 Views
18 Pages

Preparation of Cemented Carbide Insert Cutting Edge by Flexible Fiber-Assisted Shear Thickening Polishing Method

  • Lanying Shao,
  • Yu Zhou,
  • Wei Fang,
  • Jiahuan Wang,
  • Xu Wang,
  • Qianfa Deng and
  • Binghai Lyu

29 September 2022

Reasonable cutting edge preparation can eliminate microscopic defects and improve the performance of a cutting tool. The flexible fiber-assisted shear thickening polishing method was used for the preparation of cemented carbide insert cutting edge. T...

  • Article
  • Open Access
8 Citations
2,763 Views
15 Pages

To improve the cutting performance of the core drill, the flexible fiber assisted shear-thickening polishing (FF-STP) for cutting edge preparation was proposed to eliminate the microscopic defect and obtain proper radius of the cutting edge of the co...

  • Article
  • Open Access
2 Citations
1,626 Views
14 Pages

Experimental Study on Chemical–Mechanical Synergistic Preparation for Cemented Carbide Insert Cutting Edge

  • Changjiang Qin,
  • Jian Pan,
  • Lei Guo,
  • Chi Zhang,
  • Wanli Chen,
  • Zihua Hu,
  • Shengqiang Jiang,
  • Xiaogao Chen and
  • Meijiao Mao

21 December 2023

Typical edge defects in the edge region of a new cemented carbide insert without edge preparation include burrs, poor surface quality, micro-breakages, and irregularities along the edge. To address the problems in new cemented carbide inserts without...

  • Article
  • Open Access
25 Citations
3,645 Views
18 Pages

5 February 2020

Nanocomposite AlCrSiN hard coatings were deposited on the cemented carbide substrates with a negative substrate bias voltage within the range of −80 to −120 V using the cathodic arc evaporation system. The effect of variation in the bias...

  • Article
  • Open Access
3 Citations
1,956 Views
16 Pages

4 April 2024

Cutting edge preparation is a precision machining process that improves the surface quality of cutting tools through the relative movement of abrasives and the tool. Research on removing materials in drag finishing can be greatly beneficial to tool m...

  • Article
  • Open Access
1 Citations
2,307 Views
16 Pages

Simulation and Experimental Study on the Effect of Edge Radius on the Cutting Condition of Carbide Inserts

  • Shitao Chen,
  • Zhiyuan Bao,
  • Yuhong Yan,
  • Binghai Lyu,
  • Hongyu Chen,
  • Wei Hang,
  • Jinhu Wang,
  • Wenhong Zhao,
  • Julong Yuan and
  • Xu Wang

23 March 2024

Carbide tools are extensively used in the automotive, aerospace, and marine industries. However, an unsuitable tool-edge treatment can affect the cutting performance of carbide tools. In the tool-cutting process, the cutting edge radius is one of the...

  • Article
  • Open Access
7 Citations
5,793 Views
16 Pages

Influence of End Mill Manufacturing on Cutting Edge Quality and Wear Behavior

  • Berend Denkena,
  • Alexander Krödel-Worbes,
  • Sascha Beblein and
  • Markus Hein

One of the decisive factors for the performance of milling tools is the quality of the cutting edge. The latter results from the process control of the individual steps along the tool manufacturing process chain, which generally includes the sinterin...

  • Article
  • Open Access
42 Citations
6,549 Views
16 Pages

Effects of Cutting Edge Microgeometry on Residual Stress in Orthogonal Cutting of Inconel 718 by FEM

  • Qi Shen,
  • Zhanqiang Liu,
  • Yang Hua,
  • Jinfu Zhao,
  • Woyun Lv and
  • Aziz Ul Hassan Mohsan

14 June 2018

Service performance of components such as fatigue life are dramatically influenced by the machined surface and subsurface residual stresses. This paper aims at achieving a better understanding of the influence of cutting edge microgeometry on machine...

  • Article
  • Open Access
37 Citations
6,686 Views
12 Pages

The Influence of Surface Treatment of PVD Coating on Its Quality and Wear Resistant

  • Tomas Zlamal,
  • Ivan Mrkvica,
  • Tomas Szotkowski and
  • Sarka Malotova

The article deals with a determination of the influence of a cutting edge preparation on the quality and wear resistance of coated cutting tools. Cutting inserts made from a sintered carbide with a deposited layer of PVD coating were selected for mea...

  • Article
  • Open Access
1,003 Views
21 Pages

29 September 2025

Tool edge preparation is the process aimed at eliminating edge defects and optimizing the micro-geometric parameters of cutting tools. Drag finishing, the primary engineering method, subjects tools to planetary motion (simultaneous revolution and rot...

  • Article
  • Open Access
6 Citations
2,647 Views
25 Pages

23 October 2022

This paper presents a numerical investigation of the effects of chamfered and sharp cemented carbide tools using finite element method-based DEFORM-2D software and cutting parameters on different machining characteristics during the orthogonal cuttin...

  • Article
  • Open Access
6,602 Views
8 Pages

Due to increasing demands on cutting tools, cutting edge preparation is of high priority because of its influence on the tool life. Current cutting edge preparation processes are mostly limited to generating simple roundings on the cutting edge. Mult...

  • Communication
  • Open Access
6 Citations
3,026 Views
8 Pages

Cemented Carbide End-Mill Edge Preparation Using Dry-Electropolishing

  • Guiomar Riu-Perdrix,
  • Andrea Valencia-Cadena,
  • Luis Llanes and
  • Joan Josep Roa

Precision edge preparation techniques for cemented carbides enable optimization of the geometry of tools’ cutting edges. These techniques are frequently used in high-stress environments, resulting in substantial improvements in tools’ cut...

  • Article
  • Open Access
14 Citations
3,049 Views
18 Pages

Research on Using an Unconventional Tool for Increasing Tool Life by Selective Exchange of Worn Cutting Edge

  • Tadeusz Mikolajczyk,
  • Tomasz Paczkowski,
  • Mustafa Kuntoglu,
  • Abhishek D. Patange and
  • Rüstem Binali

29 December 2022

This paper proposes a novel scheme titled ‘selective exchange of the worn cutting edge (SEWCE),’ which uses the cutting edge for an extended time by replacing the worn-out edge. This possibility was investigated for single-edge cutting to...

  • Article
  • Open Access
3 Citations
2,838 Views
16 Pages

MIG and TIG Joining of AA1070 Aluminium Sheets with Different Surface Preparations

  • Elisa Fracchia,
  • Jana Bidulská,
  • Róbert Bidulský and
  • Marco Actis Grande

6 January 2022

In this work, AA1070 aluminium alloy sheets are joined using TIG and MIG welding after three different edge preparations. Shearing, water jet and plasma-cut processes were used to cut sheets, subsequently welded using ER5356 and ER4043 filler metals...

  • Article
  • Open Access
26 Citations
5,334 Views
21 Pages

Machinability Study of Hardened 1045 Steel When Milling with Ceramic Cutting Inserts

  • Mohamed Shnfir,
  • Oluwole A. Olufayo,
  • Walid Jomaa and
  • Victor Songmene

30 November 2019

Intermittent machining using ceramic tools such as hard milling is a challenging task due to the severe mechanical shock that the inserts undergo during machining and the brittleness of ceramic inserts. This study investigates the machinability of ha...

  • Article
  • Open Access
1 Citations
2,640 Views
15 Pages

This investigation sought to characterize the combined influence of cutting-edge microgeometry and cooling/lubricating strategies on process thermo-mechanics and the resultant surface integrity in orthogonal machining of the Ti-6Al-4V alloy. Reverse...

  • Article
  • Open Access
1,111 Views
34 Pages

New Approach to High-Speed Multi-Coordinate Milling Based on Kinematic Cutting Parameters and Acoustic Signals

  • Petr M. Pivkin,
  • Mikhail P. Kozochkin,
  • Artem A. Ershov,
  • Ludmila A. Uvarova,
  • Alexey B. Nadykto and
  • Sergey N. Grigoriev

In this work, a new approach to high-speed multi-coordinate milling was developed. The new approach is based on a new model of trochoidal machining; this is, in turn, based on the theoretical thickness of a chip and its ratio to the cutting edge&rsqu...

  • Article
  • Open Access
1 Citations
2,348 Views
13 Pages

23 December 2024

The Ms58 brass material was machined dry by the lathe’s external cylindrical surface turning method. Three different feeds (0.155, 0.088, and 0.028 mm/rev), 3 different cutting-edge angles (70°, 80°, and 90°), and three-spindle speeds (480, 630, and...

  • Article
  • Open Access
884 Views
15 Pages

The Cutting Edge Geometric Optimization of the PCBN Tool for the Machining of Cast Iron

  • Xian Wu,
  • Zhiqin Su,
  • Chao Zhang,
  • Xuefeng Zhao,
  • Hongfei Yao and
  • Feng Jiang

26 August 2025

The turning process is the main machining task in brake disc production, and the PCBN tool is the most suitable type of cutting tools in the machining of brake discs made of cast iron. The edge geometric optimization of the PCBN tool is the key facto...

  • Article
  • Open Access
3 Citations
1,875 Views
15 Pages

11 October 2021

Sintered zinc oxide (ZnO) ceramic is a fragile and difficult-to-cut material, so finishing operations demand handling cautious and accurate surface tolerances by polishing, grinding, or machining. The conventional machining methods based on grinding...

  • Article
  • Open Access
9 Citations
6,529 Views
27 Pages

Research on Chip Shear Angle and Built-Up Edge of Slow-Rate Machining EN C45 and EN 16MnCr5 Steels

  • Katarina Monkova,
  • Peter Pavol Monka,
  • Adriana Sekerakova,
  • Jozef Tkac,
  • Martin Bednarik,
  • Juraj Kovac and
  • Andrej Jahnatek

30 August 2019

One of the phenomena that accompanies metal cutting is extensive plastic deformation and fracture. The excess material is plastically deformed, fractured, and removed from the workpiece in the form of chips, the formation of which depends on the type...

  • Article
  • Open Access
679 Views
9 Pages

Femtosecond Laser-Assisted Donor and Recipient Preparation for Bowman Layer Transplantation

  • Rosemarie Schlosser,
  • Annekatrin Rickmann,
  • Peter Szurman,
  • Silke Wahl,
  • Berthold Seitz,
  • Philip Wakili,
  • Lisa Julia Müller,
  • Philipp Ken Roberts and
  • Karl Thomas Boden

19 June 2025

Objectives: A Ziemer LDV Z8 femtosecond laser (FSL) was used to obtain optimal cutting parameters with precise settings for donor and recipient preparations for Bowman layer transplantation. Methods: Of 48 human research corneas examined, 32 were use...

  • Article
  • Open Access
3 Citations
3,017 Views
18 Pages

Effect of Machining Conditions on Temperature and Vickers Microhardness of Chips during Planing

  • Peter Pavol Monka,
  • Katarina Monkova,
  • Martin Vasina,
  • Milena Kubisova,
  • Martin Korol and
  • Adriana Sekerakova

26 September 2022

For the machining of long and narrow surfaces and when processing multiple pieces, planing technology is used, the productivity of which can be higher than that of milling, although it is relatively slow machining. The article aims to study the degre...

  • Article
  • Open Access
1 Citations
3,110 Views
13 Pages

Quality Variation of Pork Bellies by Cutting Manner and Quality Grade

  • Pil-Nam Seong,
  • Jeong-Ah Lee,
  • Dong-Heon Song,
  • Hyun-Wook Kim,
  • Dong-Gun Kim,
  • Samooel Jung and
  • Van-Ba Hoa

30 September 2024

In the meat industry, the quality grading system is commonly applied to classify carcasses based on quality and value. Presently, to facilitate consumer convenience, pork bellies are prepared into slices and retailed in supermarkets and butchers. The...

  • Article
  • Open Access
11 Citations
4,133 Views
12 Pages

Obtaining Various Shapes of Machined Surface Using a Tool with a Multi-Insert Cutting Edge

  • Tadeusz Mikolajczyk,
  • Danil Yurievich Pimenov,
  • Catalin Iulian Pruncu,
  • Karali Patra,
  • Hubert Latos,
  • Grzegorz Krolczyk,
  • Mozammel Mia,
  • Adam Klodowski and
  • Munish Kumar Gupta

1 March 2019

A novel design of a universal form tool is presented for machining complex planar and axisymmetric surfaces. The geometric and kinematic flexibility (GKF) of this tool type means that it can machine a wide range of profiles using a single setup. The...

  • Feature Paper
  • Article
  • Open Access
10 Citations
4,064 Views
14 Pages

7 November 2022

The presented article deals with the influence of the heat treatment of C45 steel on the surface quality after turning. Turning is a machining technology used to prepare specific geometrical characteristics of surface and dimensional quality. In the...

  • Article
  • Open Access
10 Citations
2,688 Views
15 Pages

Self-Grinding Silage Knife Strengthened with Ni–WC Alloy Prepared by Laser Cladding

  • Lingfeng Xu,
  • Zhanhua Song,
  • Mingxiang Li,
  • Fade Li,
  • Jing Guo and
  • Ming Gao

1 November 2021

The working environment of agricultural cutting tools is poor, and the operational quality and efficiency are reduced after they become blunt. This study aimed to develop a high wear-resistant agriculture knife with a long life. A Ni–WC alloy, wear-r...

  • Article
  • Open Access
1 Citations
764 Views
13 Pages

15 September 2025

Microtextured cutting tools are widely used because of their excellent performance in cutting difficult-to-machine materials. The cutting performance of cutting tools largely depends on the size parameters of the microtextures used. This study focuse...

  • Article
  • Open Access
20 Citations
3,188 Views
16 Pages

Assessments of Process Parameters on Cutting Force and Surface Roughness during Drilling of AA7075/TiB2 In Situ Composite

  • S. Parasuraman,
  • I. Elamvazuthi,
  • G. Kanagaraj,
  • Elango Natarajan and
  • A. Pugazhenthi

31 March 2021

Reinforced aluminum composites are the basic class of materials for aviation and transport industries. The machinability of these composites is still an issue due to the presence of hard fillers. The current research is aimed to investigate the drill...

  • Feature Paper
  • Article
  • Open Access
22 Citations
3,356 Views
13 Pages

WC-High Entropy Alloy Reinforced Long Life Self-Grinding Silage Knife Prepared by Laser Cladding

  • Lingfeng Xu,
  • Mingxiang Li,
  • Zhanhua Song,
  • Fade Li,
  • Jing Guo and
  • Ming Gao

19 March 2022

The working environment of agricultural knives is bad, which makes the knives wear out easily. A wear resistant layer of AlCoCrFeNi high entropy alloy (HEA) reinforced by tungsten carbide (WC) was prepared by laser cladding on one side of the cutting...

  • Article
  • Open Access
2 Citations
1,611 Views
25 Pages

Design and Optimization of Power Harrow Soil Crushing Components for Coastal Saline–Alkali Land

  • Nan Xu,
  • Zhenbo Xin,
  • Jin Yuan,
  • Zenghui Gao,
  • Yu Tian,
  • Chao Xia,
  • Xuemei Liu and
  • Dongwei Wang

In China, there are approximately 36.7 million hectares of available saline–alkali land. The quality of land preparation significantly influences the yield of crops grown in saline–alkali soil. However, saline–alkali soil is highly...

  • Article
  • Open Access
2 Citations
1,994 Views
15 Pages

Thermodynamic Analysis Based on the ZL205A Alloy Milling Force Model Study

  • Jing Cui,
  • Xingquan Shen,
  • Zhijie Xin,
  • Huihu Lu,
  • Yanhao Shi,
  • Xiaobin Huang and
  • Baoyu Sun

11 September 2023

The ZL205A aluminum alloy is mostly used in automobiles, aircraft, aerospace, and other mechanical components, but now, it focuses on the study of its casting performance, and there is still a lack of research on its cutting performance. In this pape...

  • Article
  • Open Access
12 Citations
2,908 Views
14 Pages

Preparation of Micro-Pit-Textured PCD Tools and Micro-Turning Experiment on SiCp/Al Composites

  • Xu Wang,
  • Valentin L. Popov,
  • Zhanjiang Yu,
  • Yiquan Li,
  • Jinkai Xu,
  • Qiang Li and
  • Huadong Yu

19 July 2022

Serious tool wear occurs very often during machining due to the reinforcing phases in the workpiece. In this study, micro-pit-textures were prepared on the surfaces of PCD tools with a nanosecond laser to improve their cutting performance on SiCp/Al...

  • Article
  • Open Access
3,337 Views
13 Pages

Laser Beam Welding under Vacuum of Hot-Dip Galvanized Constructional Steel

  • Christian Frey,
  • Ole Stocks,
  • Simon Olschok,
  • Ronny Kühne,
  • Markus Feldmann and
  • Uwe Reisgen

Hot-dip galvanized components offer a great potential for corrosion protection of up to 100 years, while laser beam welding in vacuum (LaVa) has the advantage of high penetration depths Combined, this process chain can be economically used in steel c...

  • Review
  • Open Access
49 Citations
9,236 Views
40 Pages

Properties, Preparation and Applications of Low Dimensional Transition Metal Dichalcogenides

  • Lei Yang,
  • Chenggen Xie,
  • Juncheng Jin,
  • Rai Nauman Ali,
  • Chao Feng,
  • Ping Liu and
  • Bin Xiang

Low-dimensional layered transition metal dichalcogenides (TMDs) have recently emerged as an important fundamental research material because of their unique structural, physical and chemical properties. These novel properties make these TMDs a suitabl...

  • Article
  • Open Access
6 Citations
4,002 Views
18 Pages

The Chip Formation Process When Cutting High-Speed Steels and Ti3SiC2 Ceramics

  • Borislav Savkovic,
  • Pavel Kovac,
  • Leposava Sidjanin and
  • Dragan Rajnovic

The paper presents the microstructural characterization of the chip roots in high-speed steels and ceramic Ti3SiC2. The process of chip formation and the obtaining of adequate samples were carried out using the quick-stop method. The tests were carri...

  • Article
  • Open Access
15 Citations
6,724 Views
11 Pages

This article presents a cost-effective and reliable method for welding 30 mm thick sheets of shipbuilding steel EH36. The method proposes to perform butt welding in a two-run technique using hybrid laser arc welding (HLAW) and submerged arc welding (...

  • Article
  • Open Access
1,001 Views
14 Pages

Combined Lithium-Rich Czochralski Growth and Diffusion Method for Z-Cut Near-Stoichiometric Lithium Niobate Crystals and the Study of Periodic Domain Structures

  • Xuefeng Xiao,
  • Yan Zhang,
  • Han Zhang,
  • Jiayi Chen,
  • Yan Huang,
  • Jiashun Si,
  • Shuaijie Liang,
  • Qingyan Xu,
  • Huan Zhang and
  • Xuefeng Zhang
  • + 1 author

16 August 2025

This paper presents the preparation of Z-cut near-stoichiometric lithium niobate (NSLN) wafers using a combined process of the lithium-rich Czochralski growth and diffusion methods. The fabricated Z-cut NSLN wafers exhibited outstanding comprehensive...

  • Review
  • Open Access
19 Citations
13,201 Views
27 Pages

Ethosomes: A Promising Drug Delivery Platform for Transdermal Application

  • Bo Zhan,
  • Jiawen Wang,
  • Hongyu Li,
  • Kexin Xiao,
  • Xiaohua Fang,
  • Yajun Shi and
  • Yanyan Jia

13 September 2024

In recent years, transdermal drug delivery systems have gained considerable attention for their ability to enhance patient compliance and provide consistent drug release. However, the barrier function of the skin’s outermost layer remains the f...

  • Article
  • Open Access
2 Citations
1,303 Views
15 Pages

19 July 2024

Micro-pyramid copper molds are critical components in the preparation of high-precision optical elements, such as light-trapping films and reflective films. Their surfaces are composed of micro-pyramid arrays (MPAs). The surface roughness and edge bu...

  • Article
  • Open Access
36 Citations
4,001 Views
20 Pages

Investigation on Surface Integrity in Hard Turning of AISI 4140 Steel with SPPP-AlTiSiN Coated Carbide Insert under Nano-MQL

  • Smita Padhan,
  • Naresh Kumar Wagri,
  • Lalatendu Dash,
  • Anshuman Das,
  • Sudhansu Ranjan Das,
  • Mohammad Rafighi and
  • Priyaranjan Sharma

The machined surface integrity in the turning of hardened steels is adversely influenced by heat generation and friction which requires pacification of the temperature by the effective cooling-lubrication approach and cutting tool performance. The pr...

  • Viewpoint
  • Open Access
3 Citations
2,336 Views
10 Pages

Revamping Non-Small Cell Lung Cancer Treatments in Stages II and III: Preparing Healthcare for Cutting-Edge Immuno-Oncology Regimens

  • Luca Bertolaccini,
  • Monica Casiraghi,
  • Claudia Bardoni,
  • Cristina Diotti,
  • Matteo Chiari,
  • Antonio Mazzella,
  • Filippo de Marinis and
  • Lorenzo Spaggiari

14 August 2024

Non-small cell lung cancer (NSCLC) poses a significant challenge in clinical oncology, necessitating continual refinement of treatment approaches in stages II and III. Recent advancements have highlighted the potential of neoadjuvant therapy in optim...

  • Article
  • Open Access
20 Citations
4,570 Views
13 Pages

SEM-EDX Analysis of Metal Particles Deposition from Surgical Burs after Implant Guided Surgery Procedures

  • Giovanni Falisi,
  • Giordano Foffo,
  • Marco Severino,
  • Carlo Di Paolo,
  • Serena Bianchi,
  • Sara Bernardi,
  • Davide Pietropaoli,
  • Sofia Rastelli,
  • Roberto Gatto and
  • Gianluca Botticelli

12 February 2022

The preparation of the implant site in guided surgery procedure takes place without irrigation, which could lead to increased friction of the drills with the formation and release of debris or metal particles. The presence of metal particles in the p...

  • Review
  • Open Access
9 Citations
6,409 Views
24 Pages

Controllable Preparation and Strengthening Strategies towards High-Strength Carbon Nanotube Fibers

  • Yukang Zhu,
  • Hongjie Yue,
  • Muhammad Junaid Aslam,
  • Yunxiang Bai,
  • Zhenxing Zhu and
  • Fei Wei

5 October 2022

Carbon nanotubes (CNTs) with superior mechanical properties are expected to play a role in the next generation of critical engineering mechanical materials. Crucial advances have been made in CNTs, as it has been reported that the tensile strength of...

  • Protocol
  • Open Access
1 Citations
3,487 Views
12 Pages

An Efficient Method to Prepare Barcoded cDNA Libraries from Plant Callus for Long-Read Sequencing

  • Daniela Cordeiro,
  • Alexandra Camelo,
  • Ana Carolina Pedrosa,
  • Inês Brandão,
  • Jorge Canhoto,
  • Christophe Espírito Santo and
  • Sandra Correia

Long-read sequencing methods allow a comprehensive analysis of transcriptomes in identifying full-length transcripts. This revolutionary method represents a considerable breakthrough for non-model species since it allows enhanced gene annotation and...

  • Article
  • Open Access
1 Citations
3,115 Views
22 Pages

Special Type Routing Problems in Plane Graphs

  • Tatiana Makarovskikh and
  • Anatoly Panyukov

2 March 2022

We considered routing problems for plane graphs to solve control problems of cutting machines in the industry. According to the cutting plan, we form its homeomorphic image in the form of a plane graph G. We determine the appropriate type of route fo...

  • Abstract
  • Open Access
1,292 Views
2 Pages

Molecularly Imprinted Nanogels for Spike S1 Protein Recognition

  • Iulia Elena Neblea,
  • Anamaria Zaharia,
  • Tanța-Verona Iordache,
  • Anita-Laura Chiriac,
  • Ana-Mihaela Gavrilă,
  • Sorin-Viorel Dolana,
  • Andreea Miron,
  • Ana-Lorena Neagu,
  • Mircea Teodorescu and
  • François-Xavier Perrin

In the context of the global COVID-19 pandemic caused by the highly transmissible SARS-CoV-2 virus, molecularly imprinted polymers (MIPs) have emerged as a cutting-edge solution for the specific recognition of the Spike S1 protein, a crucial element...

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