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  • Brief Report
  • Open Access
12 Citations
1,453 Views
7 Pages

Aneurysm Wall Enhancement in Black Blood Mri Correlates with Aneurysm Size. Black Blood Mri Could Serve As an Objective Criterion of Aneurysm Stability in Near Future

  • Athanasios K. Petridis,
  • Andreas Filis,
  • Elias Chasoglou,
  • Igor Fischer,
  • Maxine Dibué-Adjei,
  • Richard Bostelmann,
  • Hans Jakob Steiger,
  • Bernd Turowski and
  • Rebecca May

27 July 2018

The increasing number of incidental intracranial aneurysms creates a dilemma of which aneurysms to treat and which to observe. Clinical scoring systems consider risk factors for aneurysm rupture however objective parameters for assessment of aneurysm...

  • Article
  • Open Access
8 Citations
2,386 Views
10 Pages

11 February 2022

The current stratification model of aneurysm rupture seems to be insufficient in some clinical cases. In our study, we determined the differences in wall structure between ruptured and unruptured aneurysms. We obtained computed tomography angiograms...

  • Article
  • Open Access
1 Citations
1,863 Views
7 Pages

Aneurysm Sac Pressure during Branched Endovascular Aneurysm Repair versus Multilayer Flow Modulator Implantation in Patients with Thoracoabdominal Aortic Aneurysm

  • Maciej Antkiewicz,
  • Wiktor Kuliczkowski,
  • Marcin Protasiewicz,
  • Tomasz Zubilewicz,
  • Piotr Terlecki,
  • Magdalena Kobielarz and
  • Dariusz Janczak

Open thoracoabdominal repair is the gold standard in the TAAA treatment. However, there are endovascular techniques, that sometimes may be an alternative, such as branched endovascular aneurysm repair (BEVAR) or implantation of the multilayer flow mo...

  • Article
  • Open Access
8 Citations
2,424 Views
7 Pages

Arterial Aneurysm Localization Is Sex-Dependent

  • Daniel Körfer,
  • Caspar Grond-Ginsbach,
  • Maani Hakimi,
  • Dittmar Böckler and
  • Philipp Erhart

27 April 2022

The aim of this study was to investigate sex-dependent aneurysm distributions. A total of 3107 patients with arterial aneurysms were diagnosed from 2006 to 2016. Patients with anything other than true aneurysms, hereditary connective tissue disorders...

  • Article
  • Open Access
7 Citations
2,271 Views
11 Pages

Relationship between Gut, Blood, Aneurysm Wall and Thrombus Microbiome in Abdominal Aortic Aneurysm Patients

  • Éva Nemes-Nikodém,
  • Gergő Péter Gyurok,
  • Zsuzsanna A. Dunai,
  • Nóra Makra,
  • Bálint Hofmeister,
  • Dóra Szabó,
  • Péter Sótonyi,
  • László Hidi,
  • Ágnes Szappanos and
  • Eszter Ostorházi
  • + 1 author

14 August 2024

Previous research confirmed gut dysbiosis and translocation of selected intestinal bacteria into the vessel wall in abdominal aortic aneurysm patients. We studied the stool, blood, thrombus and aneurysm microbiomes of 21 abdominal aortic aneurysm pat...

  • Article
  • Open Access
1,000 Views
18 Pages

Pitfalls in Intracranial Aneurysm Clipping: How to Avoid and How to Get out of Them

  • Lara Brunasso,
  • Biagia La Pira,
  • Rina Di Bonaventura,
  • Carmelo Lucio Sturiale,
  • Enrico Marchese,
  • Giovanni Sabatino and
  • Alessio Albanese

12 December 2025

Background/Objectives: Surgical clipping remains a fundamental treatment modality for intracranial aneurysms, particularly in complex cases and those not amenable to endovascular approaches. However, it is associated with several technical challenges...

  • Article
  • Open Access
5 Citations
2,451 Views
12 Pages

The Windkessel model, which is known as a successful model for explaining the hemodynamic circulation, is a mathematical model with a direct correspondence with the electric circuit. We propose a theoretical model for the intracranial aneurysm based...

  • Review
  • Open Access
157 Views
18 Pages

Structural Weakness: Collagen Alterations in Cerebral Aneurysm Development

  • Brenda Hranec,
  • Luke Hudson,
  • Sophia Kermet,
  • Meghana Bomma,
  • Madison Patrick,
  • Matthew Lawson and
  • Narlin Beaty

Background/Objectives: Aneurysms develop secondary to progressive weakening of arterial walls and remain a major cause of morbidity and mortality worldwide. Collagen, particularly fibrillar types I and III, is the primary tensile load-bearing compone...

  • Case Report
  • Open Access
1 Citations
3,209 Views
6 Pages

20 June 2024

Background: A mycotic aortic aneurysm is a rare type of aortic aneurysm that can have disastrous outcomes. Most mycotic aneurysms originate from infectious sources, such as trauma, vegetation in the heart, and adjacent infectious sources. If a mycoti...

  • Review
  • Open Access
36 Citations
5,984 Views
16 Pages

Preclinical Intracranial Aneurysm Models: A Systematic Review

  • Fabio Strange,
  • Basil E Grüter,
  • Javier Fandino and
  • Serge Marbacher

27 February 2020

Intracranial aneurysms (IA) are characterized by weakened cerebral vessel walls that may lead to rupture and subarachnoid hemorrhage. The mechanisms behind their formation and progression are yet unclear and warrant preclinical studies. This systemat...

  • Case Report
  • Open Access
2 Citations
3,056 Views
6 Pages

Beaded Coronary Aneurysm in Kawasaki Disease

  • I-Hsin Tai,
  • Kai-Sheng Hsieh and
  • Ho-Chang Kuo

24 September 2022

Kawasaki disease (KD) is a febrile systemic vasculitis that mainly affects children aged under five years old. The aneurysm formation of the coronary artery is the most common complication after KD. We report a case with multiple coronary aneurysm fo...

  • Case Report
  • Open Access
2 Citations
2,571 Views
11 Pages

Traumatic Aneurysm Involving the Posterior Communicating Artery

  • Gabriele Napoletano,
  • Nicola Di Fazio,
  • Giuseppe Delogu,
  • Fabio Del Duca and
  • Aniello Maiese

13 January 2024

Traumatic intracranial aneurysms (TICAs) are rare, accounting for less than 1% of all intracranial aneurysms. However, they are associated with a mortality rate of over 50%. The case presented herein focuses on a posterior communicating artery TICA c...

  • Article
  • Open Access
6 Citations
3,418 Views
11 Pages

Comparison of Aneurysm Patency and Mural Inflammation in an Arterial Rabbit Sidewall and Bifurcation Aneurysm Model under Consideration of Different Wall Conditions

  • Basil Erwin Grüter,
  • Stefan Wanderer,
  • Fabio Strange,
  • Sivani Sivanrupan,
  • Michael von Gunten,
  • Hans Rudolf Widmer,
  • Daniel Coluccia,
  • Lukas Andereggen,
  • Javier Fandino and
  • Serge Marbacher

Background: Biological processes that lead to aneurysm formation, growth and rupture are insufficiently understood. Vessel wall inflammation and degeneration are suggested to be the driving factors. In this study, we aimed to investigate the natural...

  • Case Report
  • Open Access
1 Citations
1,708 Views
8 Pages

Endovascular Treatment of “Donut-Shaped” Aneurysm—A Case Series

  • Dragoslav Nestorovic,
  • Igor Nikolic,
  • Ana Stankovic,
  • Mladen Bila,
  • Vladimir Cvetic,
  • Marko Miletic,
  • Vladimir Jovanovic and
  • Goran Tasic

9 July 2024

Background and Objectives: Partially thrombosed aneurysms represent a subset primarily found within large and giant aneurysms. The presence of an intraluminal thrombus can cause an aneurysm to present in different shapes upon angiographic examination...

  • Article
  • Open Access
9 Citations
4,479 Views
13 Pages

Vascular Deformation Mapping of Abdominal Aortic Aneurysm

  • Drew J. Braet,
  • Jonathan Eliason,
  • Yunus Ahmed,
  • Pieter A. J. van Bakel,
  • Jiayang Zhong,
  • Zhangxing Bian,
  • Carlos Alberto Figueroa and
  • Nicholas S. Burris

13 May 2021

Abdominal aortic aneurysm (AAA) is a complex disease that requires regular imaging surveillance to monitor for aneurysm stability. Current imaging surveillance techniques use maximum diameter, often assessed by computed tomography angiography (CTA),...

  • Article
  • Open Access
1 Citations
3,160 Views
11 Pages

Is Abdominal Aortic Aneurysm Behavior after Endovascular Repair Associated with Aneurysm Wall Density on Computed Tomography Angiography?

  • Arminas Skrebūnas,
  • Givi Lengvenis,
  • Inga Urtė Builytė,
  • Rūta Žulpaitė,
  • Rytis Bliūdžius,
  • Petras Purlys,
  • Tomas Baltrūnas,
  • Nerijus Misonis,
  • Mindaugas Matačiūnas and
  • Donatas Vajauskas
  • + 1 author

25 July 2019

Background and objectives: Abdominal aortic aneurysm (AAA) growth is unpredictable after the endovascular aneurysm repair (EVAR). Continuing aortic wall degradation and weakening due to hypoxia may have a role in post-EVAR aneurysm sac growth. We aim...

  • Case Report
  • Open Access
1 Citations
885 Views
2 Pages

Huge Aneurysm of the Proper Hepatic Artery

  • Mohamed Amine Attaoui,
  • Rached Bayar,
  • Zeineb Mzoughi,
  • Sahir Omrani,
  • Lassaad Gharbi and
  • Mohamed Taher Khalfallah

Hepatic artery aneurysms are rarely diagnosed. It is mainly because of non specific symptoms. They are generally an incidental findings during imaging studies. They are usually detected in the sixth decade, predominantly in men. We report herein a ca...

  • Article
  • Open Access
1,073 Views
19 Pages

Automated Aneurysm Boundary Detection and Volume Estimation Using Deep Learning

  • Alireza Bagheri Rajeoni,
  • Breanna Pederson,
  • Susan M. Lessner and
  • Homayoun Valafar

Background/Objective: Precise aneurysm volume measurement offers a transformative edge for risk assessment and treatment planning in clinical settings. Currently, clinical assessments rely heavily on manual review of medical imaging, a process that i...

  • Feature Paper
  • Review
  • Open Access
20 Citations
4,618 Views
10 Pages

Saccular Aneurysm Models Featuring Growth and Rupture: A Systematic Review

  • Serge Marbacher,
  • Stefan Wanderer,
  • Fabio Strange,
  • Basil E. Grüter and
  • Javier Fandino

13 February 2020

Background. Most available large animal extracranial aneurysm models feature healthy non-degenerated aneurysm pouches with stable long-term follow-ups and extensive healing reactions after endovascular treatment. This review focuses on a small subgro...

  • Review
  • Open Access
9 Citations
4,966 Views
15 Pages

Biomarkers in EndoVascular Aneurysm Repair (EVAR) and Abdominal Aortic Aneurysm: Pathophysiology and Clinical Implications

  • Francesco Stilo,
  • Vincenzo Catanese,
  • Antonio Nenna,
  • Nunzio Montelione,
  • Francesco Alberto Codispoti,
  • Emanuele Verghi,
  • Teresa Gabellini,
  • Mohamad Jawabra,
  • Massimo Chello and
  • Francesco Spinelli

Circulating biomarkers have been recently investigated among patients undergoing endovascular aortic aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA). Considering the plethora of small descriptive studies reporting potential associations be...

  • Review
  • Open Access
8 Citations
5,185 Views
18 Pages

Implantable Pressure-Sensing Devices for Monitoring Abdominal Aortic Aneurysms in Post-Endovascular Aneurysm Repair

  • Nuno P. Silva,
  • Bilal Amin,
  • Eoghan Dunne,
  • Niamh Hynes,
  • Martin O’Halloran and
  • Adnan Elahi

30 May 2024

Over the past two decades, there has been extensive research into surveillance methods for the post-endovascular repair of abdominal aortic aneurysms, highlighting the importance of these technologies in supplementing or even replacing conventional i...

  • Article
  • Open Access
14 Citations
2,680 Views
10 Pages

Are Thoracic Aortic Aneurysm Patients at Increased Risk for Cardiovascular Diseases?

  • Onur B. Dolmaci,
  • Sulayman El Mathari,
  • Antoine H. G. Driessen,
  • Robert J. M. Klautz,
  • Robert E. Poelmann,
  • Jan H. N. Lindeman and
  • Nimrat Grewal

29 December 2022

Objectives: Abdominal aortic aneurysms are associated with a sharply increased cardiovascular risk. Cardiovascular risk management is therefore recommended in prevailing guidelines for abdominal aneurysm patients. It has been hypothesized that associ...

  • Article
  • Open Access
6 Citations
3,440 Views
11 Pages

Clinical and Hemodynamic Features of Aneurysm Rupture in Coil Embolization of Intracranial Aneurysms

  • Tomoaki Suzuki,
  • Hitoshi Hasegawa,
  • Kohei Shibuya,
  • Hidemoto Fujiwara and
  • Makoto Oishi

Intraprocedural rupture (IPR) during coil embolization (CE) of an intracranial aneurysm is a significant clinical concern that necessitates a comprehensive understanding of its clinical and hemodynamic predictors. Between January 2012 and December 20...

  • Article
  • Open Access
1 Citations
2,417 Views
14 Pages

Endovascular Aneurysm Sac Embolization for Treatment of Ruptured Aneurysms in the Aortoiliac Segment Using N-Butyl-Cyanoacrylate

  • Karim Mostafa,
  • Marie Schierenbeck,
  • Jens Trentmann,
  • Hannes Gottschalk,
  • Julian Andersson,
  • Julian Pfarr,
  • Malte Sieren,
  • Olav Jansen and
  • Philipp J. Schäfer

31 March 2023

Background Aneurysmal rupture in the aortoiliac segment is a severe, life-threatening condition. Nowadays, in addition to surgical treatment, the implantation of a covered stent graft constitutes a feasible, minimally invasive treatment option. A nov...

  • Article
  • Open Access
3 Citations
2,915 Views
9 Pages

Obstructive Sleep Apnea and Its Influence on Intracranial Aneurysm

  • Tae Young Jung,
  • Eunkyu Lee,
  • Minhae Park,
  • Jin-Young Lee,
  • Yun Soo Hong,
  • Juhee Cho,
  • Eliseo Guallar,
  • Sang Duk Hong,
  • Yong Gi Jung and
  • Hyo Yeol Kim
  • + 5 authors

27 December 2023

Obstructive sleep apnea syndrome (OSAS) is associated with cerebrovascular disease, which can lead to life-threatening outcomes. The purpose of the study was to investigate the relationship between OSAS and comorbid intracranial aneurysms. We retrosp...

  • Article
  • Open Access
4 Citations
2,610 Views
14 Pages

Background: A ruptured abdominal aortic aneurysm is a severe condition associated with high mortality. Currently, the most important criterion used to estimate the risk of its rupture is the size of the aneurysm, but due to patients’ anatomical...

  • Review
  • Open Access
18 Citations
7,960 Views
16 Pages

Telomere Biology and Thoracic Aortic Aneurysm

  • Thomas Aschacher,
  • Olivia Salameh,
  • Florian Enzmann,
  • Barbara Messner and
  • Michael Bergmann

Ascending aortic aneurysms are mostly asymptomatic and present a great risk of aortic dissection or perforation. Consequently, ascending aortic aneurysms are a source of lethality with increased age. Biological aging results in progressive attrition...

  • Review
  • Open Access
3 Citations
3,713 Views
20 Pages

Cerebral Aneurysm: Filling the Gap Between Pathophysiology and Nanocarriers

  • Corneliu Toader,
  • Mugurel Petrinel Radoi,
  • Christian-Adelin Covlea,
  • Razvan-Adrian Covache-Busuioc,
  • Milena Monica Ilie,
  • Luca-Andrei Glavan,
  • Antonio-Daniel Corlatescu,
  • Horia-Petre Costin,
  • Maria-Daria Gica and
  • Nicolae Dobrin

5 November 2024

Intracranial aneurysms, characterized by abnormal dilations of cerebral arteries, pose significant health risks due to their potential to rupture, leading to subarachnoid hemorrhage with high mortality and morbidity rates. This paper aim is to explor...

  • Article
  • Open Access
30 Citations
7,311 Views
14 Pages

Aneurysm-Specific miR-221 and miR-146a Participates in Human Thoracic and Abdominal Aortic Aneurysms

  • Premakumari Venkatesh,
  • Julie Phillippi,
  • Sasanka Chukkapalli,
  • Mercedes Rivera-Kweh,
  • Irina Velsko,
  • Thomas Gleason,
  • Paul VanRyzin,
  • Seyed Hossein Aalaei-Andabili,
  • Ravi Kiran Ghanta and
  • Lakshmyya Kesavalu
  • + 2 authors

Altered microRNA expression is implicated in cardiovascular diseases. Our objective was to determine microRNA signatures in thoracic aortic aneurysms (TAAs) and abdominal aortic aneurysms (AAAs) compared with control non-aneurysmal aortic specimens....

  • Review
  • Open Access
3 Citations
1,008 Views
17 Pages

Simultaneous Endovascular Abdominal Aortic Aneurysm Repair and Open Repair of Common Femoral Artery Aneurysm: Short Case Series and Current Review

  • Spyros Papadoulas,
  • Melina Stathopoulou,
  • Andreas Tsimpoukis,
  • Chrysanthi Papageorgopoulou,
  • Konstantinos Nikolakopoulos,
  • Nikolaos Krinos,
  • Aliki Skandali,
  • Petros Zampakis,
  • Petraq Mustaqe and
  • Vasileios Leivaditis
  • + 2 authors

11 November 2025

Background: Common femoral artery aneurysms are rare and are usually associated with aneurysms at other sites, mainly the aorta, iliac, popliteal, superficial femoral, and profunda femoral artery. This combination poses the challenge of synchronous r...

  • Article
  • Open Access
7 Citations
2,823 Views
15 Pages

Association of Aneurysm Tissue Neutrophil Mediator Levels with Intraluminal Thrombus Thickness in Patients with Abdominal Aortic Aneurysm

  • Aldona Siennicka,
  • Monika Adamowicz,
  • Natalie Grzesch,
  • Magdalena Kłysz,
  • Jarosław Woźniak,
  • Miłosław Cnotliwy,
  • Katarzyna Galant and
  • Maria Jastrzębska

4 February 2022

An intraluminal thrombus (ILT), which accumulates large numbers of neutrophils, plays a key role in abdominal aortic aneurysm (AAA) pathogenesis. This study aimed to compare levels of selected neutrophil inflammatory mediators in thick and thin ILT,...

  • Hypothesis
  • Open Access
1 Citations
2,444 Views
11 Pages

Dynamic Loading—A New Marker for Abdominal Aneurysm Growth?

  • John Friesen,
  • Lucas Stein,
  • Farzin Adili and
  • Peter F. Pelz

19 February 2023

The growing possibilities of non-invasive heart rate and blood pressure measurement with mobile devices allow vital data to be continuously collected and used to assess patients’ health status. When it comes to the risk assessment of abdominal...

  • Article
  • Open Access
7 Citations
2,724 Views
7 Pages

Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery

  • Bedjan Behmanesh,
  • Florian Gessler,
  • Elisabeth Adam,
  • Ulrich Strouhal,
  • Sae-Yeon Won,
  • Daniel Dubinski,
  • Volker Seifert,
  • Juergen Konczalla and
  • Christian Senft

7 December 2021

Background. The use and effectiveness of intraoperative cell salvage has been analyzed in many surgical specialties. Until now, no data exist evaluating the efficacy of intraoperative cell salvage in cerebral aneurysm surgery. Aim. To evaluate the ef...

  • Case Report
  • Open Access
10 Citations
2 Views
3 Pages

Streptococcus pyogenes aortic aneurysm infection: forgotten but not gone

  • Bradley J. Gardiner,
  • Joy Wong,
  • Ming Yii,
  • Timothy Buckenham and
  • Tony M. Korman

Historically, Streptococcus pyogenes was a common cause of endocarditis and infected aortic aneurysm. Today, endovascular infections due to this organism have become exceedingly rare. We report the first case of aortic aneurysm infection due to S. py...

  • Interesting Images
  • Open Access
3 Citations
1,417 Views
4 Pages

Coanda Effect Displayed in a Giant Intracranial Aneurysm

  • Corneliu Toader,
  • Petrinel Mugurel Rădoi,
  • Ghaith Saleh R. Aljboor,
  • Luca-Andrei Glavan,
  • Razvan-Adrian Covache-Busuioc,
  • Milena-Monica Ilie and
  • Alexandru Vlad Ciurea

5 September 2024

The Coanda effect is a fluid dynamics phenomenon in which a fluid jet adheres to a convex or flat surface. This effect occurs when a liquid or gas jet emerging from an orifice clings to an adjacent surface and entrains the surrounding fluid, creating...

  • Communication
  • Open Access
19 Citations
4,181 Views
10 Pages

Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth

  • Emily R. Nordahl,
  • Susheil Uthamaraj,
  • Kendall D. Dennis,
  • Alena Sejkorová,
  • Aleš Hejčl,
  • Jaroslav Hron,
  • Helena Švihlová,
  • Kent D. Carlson,
  • Yildirim Bora Suzen and
  • Dan Dragomir-Daescu

Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance wi...

  • Article
  • Open Access
15 Citations
6,140 Views
18 Pages

Hemodynamic Investigation of the Flow Diverter Treatment of Intracranial Aneurysm

  • Maria Antonietta Boniforti,
  • Roberto Magini and
  • Tania Orosco Salinas

24 June 2023

Flow diverter stents (FDS) are increasingly used for the treatment of complex intracranial aneurysms such as fusiform, giant, or wide-neck aneurysms. The primary goal of these devices is to reconstruct the diseased vascular segment by diverting blood...

  • Article
  • Open Access
9 Citations
4,664 Views
20 Pages

The Hemodynamics of Aneurysms Treated with Flow-Diverting Stents Considering both Stent and Aneurysm/Artery Geometries

  • Paulo R. Cillo-Velasco,
  • Rafaello D. Luciano,
  • Michael E. Kelly,
  • Lissa Peeling,
  • Donald J. Bergstrom,
  • Xiongbiao Chen and
  • Mauro Malvè

29 July 2020

Flow diverting stents are deployed to reduce the blood flow into the aneurysm, which would thereby induce thrombosis in the aneurysm sac; the stents prevent its rupture. The present study aimed to examine and quantify the impacts of different flow st...

  • Interesting Images
  • Open Access
3 Citations
2,949 Views
5 Pages

An Unruptured True Aneurysm of the Uterine Artery during Pregnancy

  • Charuwan Tantipalakorn,
  • Suchaya Luewan,
  • Sirinart Sirilert and
  • Theera Tongsong

11 October 2022

The antenatal diagnosis of an unruptured true aneurysm of the uterine artery is extremely rare and has never been reported, whereas pseudoaneurysms associated with previous trauma or cesarean section have been reported several times. True aneurysms o...

  • Review
  • Open Access
38 Citations
9,239 Views
44 Pages

Insights on the Pathogenesis of Aneurysm through the Study of Hereditary Aortopathies

  • Tyler J. Creamer,
  • Emily E. Bramel and
  • Elena Gallo MacFarlane

27 January 2021

Thoracic aortic aneurysms (TAA) are permanent and localized dilations of the aorta that predispose patients to a life-threatening risk of aortic dissection or rupture. The identification of pathogenic variants that cause hereditary forms of TAA has d...

  • Case Report
  • Open Access
1 Citations
4,494 Views
8 Pages

28 January 2020

Severe spontaneous subarachnoid hemorrhage (SAH) is predominantly caused by aneurysm rupture, with non-aneurysmal vascular lesions representing only a minority of possible causes. We present the case of a 58-year old lady with a coincidental posterio...

  • Article
  • Open Access
16 Citations
4,995 Views
21 Pages

Cycloastragenol Inhibits Experimental Abdominal Aortic Aneurysm Progression

  • Leander Gaarde Melin,
  • Julie Husted Dall,
  • Jes S. Lindholt,
  • Lasse B. Steffensen,
  • Hans Christian Beck,
  • Sophie L. Elkrog,
  • Pernille D. Clausen,
  • Lars Melholt Rasmussen and
  • Jane Stubbe

The pathogenesis of abdominal aortic aneurysm involves vascular inflammation and elastin degradation. Astragalusradix contains cycloastragenol, which is known to be anti-inflammatory and to protect against elastin degradation. We hypothesized that cy...

  • Article
  • Open Access
472 Views
13 Pages

4 November 2025

Background and Objectives: To evaluate factors affecting aneurysm rupture, present our surgical experience with intracranial aneurysms, specifically using the picket-fence clipping technique for giant aneurysms, and highlight the complementary roles...

  • Review
  • Open Access
4 Citations
4,362 Views
14 Pages

Pharmaceutical Modulation of Intracranial Aneurysm Development and Rupture

  • Alex Crane,
  • Regan M. Shanahan,
  • Joseph S. Hudson,
  • Kamil W. Nowicki,
  • Zachary C. Gersey,
  • Prateek Agarwal,
  • Rachel C. Jacobs,
  • Michael J. Lang and
  • Bradley Gross

5 June 2024

Management of intracranial aneurysms (IAs) is determined by patient age, risk of rupture, and comorbid conditions. While endovascular and microsurgical interventions offer solutions to mitigate the risk of rupture, pharmacological management strategi...

  • Case Report
  • Open Access
9 Citations
1,509 Views
8 Pages

Navigating the Rare and Dangerous: Successful Clipping of a Superior Cerebellar Artery Aneurysm Against the Odds of Uncontrolled Hypertension

  • Corneliu Toader,
  • Matei Serban,
  • Razvan-Adrian Covache-Busuioc,
  • Mugurel Petrinel Radoi,
  • Ghaith Saleh Radi Aljboor,
  • Luca-Andrei Glavan,
  • Antonio Daniel Corlatescu,
  • Milena-Monica Ilie and
  • Radu M. Gorgan

6 December 2024

Background/Objectives: Superior cerebellar artery (SCA) aneurysms are exceedingly rare, posing unique diagnostic and management challenges due to their complex anatomical location within the posterior circulation. The proximity of the SCA to vital st...

  • Article
  • Open Access
4 Citations
1,514 Views
12 Pages

Aneurysmal Wall Enhancement of Non-Ruptured Intracranial Aneurysms after Endovascular Treatment Correlates with Higher Aneurysm Reperfusion Rates, but Only in Large Aneurysms

  • Valentin Ladenhauf,
  • Malik Galijasevic,
  • Milovan Regodic,
  • Raimund Helbok,
  • Verena Rass,
  • Christian Freyschlag,
  • Ondra Petr,
  • Johannes Deeg,
  • Leonhard Gruber and
  • Astrid Ellen Grams
  • + 2 authors

Introduction: Aneurysmal wall enhancement (AWE) of non-ruptured sacular intracranial aneurysms (IA) after endovascular treatment (ET) is a frequently observed imaging finding using AWE-sequences in brain magnetic resonance imaging (MRI). So far, its...

  • Article
  • Open Access
4 Citations
3,621 Views
16 Pages

Biomechanical Modeling of Cerebral Aneurysm Progression to Estimate Rupture Risk

  • Prem Nath Yadav,
  • Gurpreet Singh,
  • Shubham Gupta and
  • Arnab Chanda

A cerebral aneurysm is a medical condition described as the bulging out of the cerebral artery under adverse pressure conditions. Patients with such medical conditions have a mortality of 20% and additional morbidity of 30–40% due to aneurysm r...

  • Article
  • Open Access
837 Views
16 Pages

Microsurgical Clipping of Unruptured Anterior Communicating Artery Aneurysm—A Single-Center Experience

  • Nico Stroh-Holly,
  • Stefan Aspalter,
  • Milan Slavomir Vosko,
  • Benjamin Laudien,
  • Philipp Hermann,
  • Helga Wagner,
  • Michael Sonnberger,
  • Maria Gollwitzer,
  • Philip Rauch and
  • Matthias Gmeiner
  • + 2 authors

27 November 2025

Background/Objectives: Unruptured aneurysms of the anterior communicating artery (AComA) are associated with a higher risk of rupture and present unique anatomical challenges. Although endovascular techniques have advanced considerably, microsurgical...

  • Communication
  • Open Access
5 Citations
2,405 Views
8 Pages

The aim of this study was to investigate histopathological differences in abdominal aortic aneurysms (AAAs) between patients with multiple and single arterial aneurysms, as we suspect that there are different underlying mechanisms in aneurysm formati...

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