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39 Results Found

  • Article
  • Open Access
23 Citations
8,210 Views
11 Pages

As the prevalence of Lyme disease increases across Canada, it is imperative that the educational needs of at-risk groups be identified. The current study compared the level of knowledge and the knowledge needs about Lyme disease among individuals tha...

(This article belongs to the Special Issue Ticks and Tick Vectored Diseases—Biology to Society)
  • Article
  • Open Access
2 Citations
3,555 Views
33 Pages

26 October 2023

Ticks are acarids that can transmit diseases, such as Lyme borreliosis, to human beings. They have often been considered from an ecological perspective (the environments in which they live) or from a medical one (diagnosis and treatment), while relat...

(This article belongs to the Special Issue Contemporary Local Governance, Wellbeing and Sustainability)
  • Article
  • Open Access
2 Citations
2,483 Views
14 Pages

8 August 2025

Background/Objectives: Tick-borne diseases (TBDs) are a significant public health problem and are expanding to formerly naive areas of the United States, such as the lower Midwest. To counter TBDs, many researchers apply the Knowledge, Attitudes, Pra...

(This article belongs to the Section Health Assessments)
  • Review
  • Open Access
19 Citations
6,380 Views
31 Pages

Baggio–Yoshinari Syndrome (BYS) is an emerging Brazilian tick-borne infectious disease that clinically mimics Lyme Disease (LD) present in the Northern Hemisphere. LD is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato com...

(This article belongs to the Special Issue Lyme Borreliosis and tick-borne infections)
  • Review
  • Open Access
4 Citations
4,699 Views
8 Pages

Examining Infant and Child Neurodevelopmental Outcomes After Lyme Disease During Pregnancy

  • Meagan E. Williams,
  • David A. Schwartz,
  • Roberta L. DeBiasi and
  • Sarah B. Mulkey

22 November 2024

Lyme disease is the most common vector-borne disease in the United States. Recent environmental and socioecological changes have led to an increased incidence of Lyme and other tick-borne diseases, which enhances the urgency of identifying and mitiga...

(This article belongs to the Special Issue The Future of Vector-Borne Diseases in a Changing World)
  • Review
  • Open Access
18 Citations
13,200 Views
13 Pages

Lyme Disease: A Review with Emphasis on Latin America

  • Vanina Lucca,
  • Sandra Nuñez,
  • María Belen Pucheta,
  • Nilda Radman and ,
  • Teresita Rigonatto,
  • Graciela Sánchez,
  • Beatriz Del Curto,
  • Dolores Oliva,
  • Betina Mariño and
  • Nestor Oscar Stanchi
  • + 8 authors+ 3 authors

The spirochete Borrelia burgdorferi sensu lato (Lyme Group) is the causative agent of Lyme disease, transmitted to humans through tick bites carrying the bacteria. Common symptoms include fever, headache, fatigue, and the characteristic erythema migr...

(This article belongs to the Special Issue Borreliosis and Other Tick-Borne Diseases in the Northern and Southern Hemispheres)
  • Article
  • Open Access
1 Citations
7,078 Views
15 Pages

Lyme disease patient organizations have formed to challenge a health system that is failing Canadians who suffer from a disease that is ambiguous in its symptomology and trajectory. The framework of an embodied health movement illustrates the importa...

  • Article
  • Open Access
1 Citations
3,200 Views
11 Pages

College Students’ Knowledge of Ticks in Oklahoma: Assessment and Insights

  • Elise Knowlton,
  • Justin L. Talley,
  • Bruce H. Noden and
  • William Wyatt Hoback

20 July 2021

Ticks (Arachnida: Acari) are common in Oklahoma and may transmit tick-borne diseases (TBDs) to people. Due to the difficulty in reducing tick populations, awareness of tick bite prevention, proper tick removal, and knowledge of when to seek medical t...

  • Review
  • Open Access
143 Citations
8,822 Views
52 Pages

Lyme Disease in Humans

  • Justin D. Radolf,
  • Klemen Strle,
  • Jacob E. Lemieux and
  • Franc Strle

11 December 2020

Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread throughout the Northern Hemisphere, continues to increase globally due to m...

  • Review
  • Open Access
23 Citations
10,900 Views
14 Pages

Lyme borreliosis is the most prevalent tick-borne disease in the United States, infecting ~476,000 people annually. Borrelia spp. spirochetal bacteria are the causative agents of Lyme disease in humans and are transmitted by Ixodes spp ticks. Clinica...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Review
  • Open Access
52 Citations
14,833 Views
17 Pages

Lyme disease (LD) has become the most common vector-borne illness in the northern hemisphere. The causative agent, Borrelia burgdorferi sensu lato, is capable of establishing a persistent infection within the host. This is despite the activation of b...

(This article belongs to the Special Issue The Twists and Turns of Pathogenic Spirochetes: Novel Insights for Prevention, Diagnosis and Treatment)
  • Review
  • Open Access
10 Citations
11,586 Views
25 Pages

Lyme disease (LD) is an increasingly prevalent, climate change-accelerated, vector-borne infectious disease with significant morbidity and cost in a proportion of patients who experience ongoing symptoms after antibiotic treatment, a condition known...

(This article belongs to the Special Issue Antibiotics Resistance of Borrelia)
  • Review
  • Open Access
2 Citations
3,486 Views
17 Pages

Tick-borne co-infections are an increasingly recognized and clinically important aspect of Lyme borreliosis, particularly in regions where Ixodes ticks transmit a wide range of bacterial, protozoan, and viral pathogens. In addition to Borrelia burgdo...

(This article belongs to the Special Issue Emerging Perspectives in Lyme Disease: Microbial Interactions, Host Responses, and Therapeutic Innovations)
  • Communication
  • Open Access
3 Citations
3,105 Views
9 Pages

Middle-School Student Engagement in a Tick Testing Community Science Project

  • Amy Prunuske,
  • Cole Fisher,
  • Jhomary Molden,
  • Amarpreet Brar and ,
  • Ryan Ragland and
  • Jesse vanWestrienen
  • + 1 author+ 0 author

18 December 2021

Studies of tickborne illness have benefited from interactions between scientists and community members. Most participants in community science projects are well-educated adults, but there are anticipated benefits from engaging younger students in res...

(This article belongs to the Special Issue Citizen Science Approaches to Vector Surveillance)
  • Review
  • Open Access
20 Citations
12,400 Views
21 Pages

22 June 2021

Lyme disease is the most common vector-borne illness in North America and Europe. Its causative agents are spirochetes of the Borrelia burgdorferi sensu latu complex. Infection with borreliae can manifest in different tissues, most com...

(This article belongs to the Special Issue Advances in the Biology of Leptospira, Borrelia and Other Spirochetes)
  • Article
  • Open Access
14 Citations
4,061 Views
12 Pages

Lyme borreliosis is one of the most prevalent tick-borne infectious zoonotic diseases caused by spirochetes of the Borrelia burgdorferi sensu lato group. The present study assessed the risk factors and prevalence of Lyme borreliosis in ticks parasiti...

(This article belongs to the Special Issue Advance in Tick-Borne Diseases Research)
  • Review
  • Open Access
25 Citations
6,811 Views
17 Pages

Ecology of Ixodes pacificus Ticks and Associated Pathogens in the Western United States

  • Molly McVicar,
  • Isabella Rivera,
  • Jeremiah B. Reyes and
  • Monika Gulia-Nuss

13 January 2022

Lyme disease is the most important vector-borne disease in the United States and is increasing in incidence and geographic range. In the Pacific west, the western black-legged tick, Ixodes pacificus Cooley and Kohls, 1943 is an important vector of th...

(This article belongs to the Special Issue Current Research on Hard Tick-Borne Diseases)
  • Article
  • Open Access
1 Citations
1,700 Views
16 Pages

Experience of a Romanian Lyme Borreliosis Centre in the Multidisciplinary Management of Patients Evaluated for Suspected Lyme Neuroborreliosis

  • Violeta Briciu,
  • Angela Monica Ionicǎ,
  • Simona Mureşan,
  • Astrid Binder and ,
  • Cristina Cismaru,
  • Oana Stan,
  • Blanca Szolga,
  • Cǎtǎlina Hǎpǎianu,
  • Mirela Flonta and
  • Mihaela Lupşe
  • + 5 authors+ 0 author

Lyme neuroborreliosis (LNB) may mimic other neurological diseases, while neurological diseases may be misdiagnosed as LNB. The aims of the study were to contribute to the knowledge regarding the epidemiology and clinical manifestations of LNB, discus...

(This article belongs to the Special Issue Infectious Disease Surveillance in Romania: Second Edition)
  • Review
  • Open Access
7 Citations
5,755 Views
35 Pages

Silent Carriers: The Role of Rodents in the Emergence of Zoonotic Bacterial Threats

  • Shereen Basiouni,
  • Alfonso J. Rodriguez-Morales,
  • Awad A. Shehata and
  • Phelipe Magalhães Duarte

15 September 2025

Rodents are recognized as significant reservoirs for a broad range of zoonotic pathogens, including bacteria, viruses, and parasites, many of which have substantial implications for human and animal health. The intensifying interaction between humans...

(This article belongs to the Special Issue New Insights into Zoonotic Intracellular Pathogens)
  • Review
  • Open Access
7 Citations
7,069 Views
34 Pages

28 September 2023

Human Lyme borreliosis (LB) represents a multisystem disorder that can progress in stages. The causative agents are transmitted by hard ticks of the Ixodes ricinus complex that have been infected with the spirochete Borrelia burgdorferi sensu lato. T...

(This article belongs to the Special Issue Pathogenesis, Epidemiology, Host Response and Control of Lyme Disease and Other Tick-Borne Diseases)
  • Article
  • Open Access
37 Citations
10,549 Views
19 Pages

Using the Gravity Model to Estimate the Spatial Spread of Vector-Borne Diseases

  • José Miguel Barrios,
  • Willem W. Verstraeten,
  • Piet Maes,
  • Jean-Marie Aerts and ,
  • Jamshid Farifteh and
  • Pol Coppin
  • + 1 author+ 0 author

The gravity models are commonly used spatial interaction models. They have been widely applied in a large set of domains dealing with interactions amongst spatial entities. The spread of vector-borne diseases is also related to the intensity of inter...

(This article belongs to the Special Issue Environmental Determinants of Infectious Disease Transmission)
  • Article
  • Open Access
49 Citations
6,039 Views
11 Pages

Impacts of Deciduous Leaf Litter and Snow Presence on Nymphal Ixodes scapularis (Acari: Ixodidae) Overwintering Survival in Coastal New England, USA

  • Megan A. Linske,
  • Kirby C. Stafford,
  • Scott C. Williams,
  • Charles B. Lubelczyk and ,
  • Margret Welch and
  • Elizabeth F. Henderson
  • + 1 author+ 0 author

30 July 2019

Blacklegged ticks (Ixodes scapularis Say) are the vector for pathogens that cause more cases of human disease than any other arthropod. Lyme disease is the most common, caused by the bacterial spirochete Borrelia burgdorferi (Johnson, Schmid, Hyde, S...

(This article belongs to the Special Issue Tick Surveillance and Tick-borne Diseases)
  • Article
  • Open Access
9 Citations
3,232 Views
12 Pages

Knowledge, Attitudes, and Behaviors Regarding Lyme Borreliosis Prevention in the Endemic Area of Northeastern Poland

  • Marta Wozinska,
  • Kacper Toczylowski,
  • Dawid Lewandowski,
  • Ewa Bojkiewicz and
  • Artur Sulik

16 December 2022

(1) Background: The incidence of Lyme borreliosis (LB) is increasing in Europe. The new LB vaccine is still in clinical development, thus the dissemination of knowledge about the disease is essential. We assessed the knowledge, attitudes and preventi...

(This article belongs to the Section Epidemiology and Vaccination)
  • Article
  • Open Access
1 Citations
1,346 Views
15 Pages

The Challenge of Lyme Borreliosis: Knowledge, Attitudes, and Practices in France

  • Cynthia Philibert,
  • Joana Ferrolho,
  • Mark S. Gibson,
  • Sérgio Ramalho de Sousa and ,
  • Hugo Vilhena and
  • Sofia Anastácio
  • + 1 author+ 0 author

17 September 2025

Lyme borreliosis (LB), a zoonotic disease caused by Borrelia burgdorferi sensu lato and transmitted by Ixodes ricinus, is increasingly relevant in France, yet data on public awareness and prevention are limited. This cross-sectional study assessed th...

(This article belongs to the Section Microbiology)
  • Review
  • Open Access
49 Citations
17,993 Views
16 Pages

4 April 2020

Spirochetes can be distinguished from other flagellated bacteria by their long, thin, spiral (or wavy) cell bodies and endoflagella that reside within the periplasmic space, designated as periplasmic flagella (PFs). Some members of the spirochetes ar...

(This article belongs to the Special Issue Perspectives on Bacterial Flagellar Motor)
  • Article
  • Open Access
17 Citations
4,179 Views
8 Pages

Molecular Detection of Novel Borrelia Species, Candidatus Borrelia javanense, in Amblyomma javanense Ticks from Pangolins

  • Bao-Gui Jiang,
  • Ai-Qiong Wu,
  • Jia-Fu Jiang,
  • Ting-Ting Yuan and ,
  • Qiang Xu,
  • Chen-Long Lv,
  • Jin-Jin Chen,
  • Yi Sun,
  • Li-Qun Fang and
  • Teng-Cheng Que
  • + 6 authors+ 1 author

A novel Borrelia species, Candidatus Borrelia javanense, was found in ectoparasite ticks, Amblyomma javanense, from Manis javanica pangolins seized in anti-smuggling operations in southern China. Overall, 12 tick samples in 227 (overall prevalence 5....

(This article belongs to the Special Issue Ticks and Tick-Borne Pathogens at the Wildlife–Domestic Interface)
  • Review
  • Open Access
75 Citations
9,125 Views
12 Pages

One Health Approach to Tick and Tick-Borne Disease Surveillance in the United Kingdom

  • Nicholas Johnson,
  • Lawrence Paul Phipps,
  • Kayleigh M. Hansford,
  • Arran J. Folly and ,
  • Anthony R. Fooks,
  • Jolyon M. Medlock and
  • Karen L. Mansfield
  • + 2 authors+ 0 author

Where ticks are found, tick-borne diseases can present a threat to human and animal health. The aetiology of many of these important diseases, including Lyme disease, bovine babesiosis, tick-borne fever and louping ill, have been known for decades wh...

  • Article
  • Open Access
4 Citations
2,564 Views
20 Pages

Multiple-Perspective Data-Driven Analysis of Online Health Communities

  • Rana Alnashwan,
  • Adrian O’Riordan and
  • Humphrey Sorensen

12 October 2023

The growth of online health communities and socially generated health-related content has the potential to provide considerable value for patients and healthcare providers alike. For example, members of the public can acquire medical knowledge and in...

(This article belongs to the Special Issue Data Mining and Sentiment Analysis in Healthcare)
  • Article
  • Open Access
928 Views
21 Pages

3 December 2025

Monitoring the occurrence of Borreliaceae spirochetes in ticks may provide an indication of the risks of acquiring Lyme borreliosis (LB) and Borrelia miyamotoi disease (BMD). All ticks obtained in our study from humans in the years 2018–2022 (n...

(This article belongs to the Section Ticks)
  • Review
  • Open Access
41 Citations
18,772 Views
14 Pages

Do Tick Attachment Times Vary between Different Tick-Pathogen Systems?

  • Stephanie L. Richards,
  • Ricky Langley,
  • Charles S. Apperson and
  • Elizabeth Watson

Improvements to risk assessments are needed to enhance our understanding of tick-borne disease epidemiology. We review tick vectors and duration of tick attachment required for pathogen transmission for the following pathogens/toxins and diseases: (1...

(This article belongs to the Special Issue Human Exposure to Environmental Contaminants)
  • Article
  • Open Access
41 Citations
6,668 Views
16 Pages

Hedgehogs, Squirrels, and Blackbirds as Sentinel Hosts for Active Surveillance of Borrelia miyamotoi and Borrelia burgdorferi Complex in Urban and Rural Environments

  • Karolina Majerová,
  • Václav Hönig,
  • Michal Houda,
  • Petr Papežík and ,
  • Manoj Fonville,
  • Hein Sprong,
  • Natalie Rudenko,
  • Maryna Golovchenko,
  • Barbora Černá Bolfíková and
  • David Modrý
  • + 9 authors+ 4 authors

Lyme borreliosis (LB), caused by spirochetes of the Borrelia burgdorferi sensu lato (s.l.) complex, is one of the most common vector-borne zoonotic diseases in Europe. Knowledge about the enzootic circulation of Borrelia pathogens between ticks and t...

(This article belongs to the Special Issue Zoonotic Pathogens: A One Health Approach)
  • Article
  • Open Access
3 Citations
3,912 Views
11 Pages

9 August 2023

Will a warmer world be a sicker world? What is it about the New England landscape that supports the proliferation of Lyme disease? How are local wildlife trade and global species invasions contributors to emerging diseases such as the 2003 outbreak o...

(This article belongs to the Special Issue Planetary Health: Building the Field and Growing the Movement (Including Manuscripts 2022 Planetary Health Annual Meeting and Festival))
  • Review
  • Open Access
37 Citations
35,715 Views
23 Pages

There is increasing evidence and recognition that Lyme borreliosis (LB) causes mental symptoms. This article draws from databases, search engines and clinical experience to review current information on LB. LB causes immune and metabolic effects that...

(This article belongs to the Special Issue Lyme Disease: The Role of Big Data, Companion Diagnostics and Precision Medicine)
  • Brief Report
  • Open Access
14 Citations
3,799 Views
7 Pages

9 November 2021

Ticks are vectors that spread pathogenic bacteria, viruses, and protozoa. As the number of ticks increases due to climate change, the importance of the study of tick-borne pathogens has also increased. This study was conducted to investigate the dist...

(This article belongs to the Special Issue Vector-Borne Infections: From Ecology to Vector-Microbe-Host Interactions)
  • Article
  • Open Access
4 Citations
3,613 Views
12 Pages

Twenty Years of Lyme Borreliosis in the Netherlands: Temporal Trends in Seroprevalence and Risk Factors

  • B. J. A. Hoeve-Bakker,
  • Oda E. van den Berg,
  • H. S. Doppenberg,
  • Fiona R. M. van der Klis and ,
  • Cees C. van den Wijngaard,
  • Jan A. J. W. Kluytmans,
  • Steven F. T. Thijsen and
  • Karen Kerkhof
  • + 3 authors+ 0 author

Lyme borreliosis (LB) is not notifiable in many European countries, and the patchwork of surveillance strategies in Europe perpetuates knowledge gaps. In the Netherlands, LB incidence has been estimated from recurring general practitioner surveys sin...

(This article belongs to the Special Issue Borreliosis and Other Tick-Borne Diseases in the Northern and Southern Hemispheres)
  • Article
  • Open Access
6 Citations
4,813 Views
13 Pages

Knowledge, Attitudes and Behaviors regarding Tick-Borne Encephalitis Vaccination and Prevention of Tick-Borne Diseases among Primary Care Physicians in Bavaria and Baden-Wuerttemberg, Germany, May–September 2022

  • Liza Coyer,
  • Aylin Sogan-Ekinci,
  • Benedikt Greutélaers,
  • Julia Kuhn and ,
  • Franziska S. Saller,
  • Jana Hailer,
  • Stefanie Böhm,
  • Rainer Brosch,
  • Christiane Wagner-Wiening and
  • Merle M. Böhmer
  • + 5 authors+ 0 author

In 2020, a record number of tick-borne encephalitis (TBE) cases was reported in major endemic areas in Germany, i.e., the southern federal states of Baden-Wuerttemberg and Bavaria. Most cases were unvaccinated. Other tick-borne diseases (TBDs), inclu...

(This article belongs to the Section Public Health Microbiology)
  • Article
  • Open Access
5 Citations
2,688 Views
9 Pages

Antibodies against Borrelia burgdorferi Sensu Lato in Clinically Healthy and Sick Horses: First Report from the Czech Republic

  • Nikola Kašpárková,
  • Eva Bártová,
  • Alena Žákovská,
  • Marie Budíková and
  • Kamil Sedlák

Lyme disease, caused by some strains of bacterial spirochetes Borrelia burgdorferi sensu lato (Bbsl), affects humans but also domestic animals including horses. The primary pathogens in horses in Europe are B. afzelii, B. garinii and B. bur...

(This article belongs to the Special Issue Ticks and Tick-Borne Diseases in Animals)
  • Article
  • Open Access
2 Citations
2,899 Views
13 Pages

Barriers and Predictors of Lyme Disease Vaccine Acceptance: A Cross-Sectional Study in Poland

  • Dawid Lewandowski,
  • Artur Sulik,
  • Filip Raciborski,
  • Milena Krasnodebska and ,
  • Joanna Gebarowska,
  • Aleksandra Stalewska and
  • Kacper Toczylowski
  • + 2 authors+ 0 author

10 January 2025

Background/Objectives: Lyme disease (LD) is a major public health problem in Europe and the United States, with increasing incidence and not many prevention options. Vaccine hesitancy might be a significant barrier to successful vaccination campaigns...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
  • Article
  • Open Access
2 Citations
4,482 Views
10 Pages

Pediatric Lyme Disease in Northern Italy: An 18-Year Single-Center Case Series

  • Federica Forlanini,
  • Raffaella Di Tonno,
  • Roberta Caiazzo,
  • Daniela David and ,
  • Maria Sole Valentino,
  • Sara Giordana Rimoldi,
  • Gian Vincenzo Zuccotti,
  • Giusto Trevisan,
  • Francesca Wanda Basile and
  • Vania Giacomet
  • + 5 authors+ 0 author

Tracing the profile of pediatric Lyme borreliosis (LB) in Europe is difficult due to the interregional variation in its incidence and lack in notifications. Moreover, the identification of LB can be challenging. This study is an 18-year case series o...

(This article belongs to the Special Issue Borreliosis and Other Tick-Borne Diseases in the Northern and Southern Hemispheres)