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Special Issue "Lyme Disease: The Role of Big Data, Companion Diagnostics and Precision Medicine"
A special issue of Healthcare (ISSN 2227-9032).
Deadline for manuscript submissions: closed (30 June 2018).
Lyme disease, caused by the spirochete Borrelia burgdorferi, has become a major worldwide epidemic. Studies based on Big Data registries show that >300,000 people are diagnosed with Lyme disease each year in the USA alone, and up to two-thirds of individuals infected with B. burgdorferi will fail conventional 30-year-old antibiotic therapy. Recent studies have highlighted metabolic and molecular persistence mechanisms that allow the Lyme spirochete to survive in the face of immunological and antibiotic challenges. Consequently, improved companion diagnostic tests and novel treatment approaches for Lyme disease are urgently needed to combat the epidemic. In particular, therapies based on the principles of precision medicine could be modeled on successful “designer drug” treatment for other diseases. This Special Issue of Healthcare examines the use of Big Data registries, companion diagnostics and precision medicine that will revolutionize the diagnosis and treatment of Lyme disease in the coming years.
Dr. Raphael B. Stricker
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Lyme disease
- Borrelia burgdorferi
- tickborne diseases
- persistent infection