157,917 Results Found

Recent studies showed that Fatty Acid Synthase (FASN), a lipogenic enzyme overexpressed in several carcinomas, plays an important role in drug resistance. Furthermore, the enrichment of Breast Cancer Stem Cell (BCSC) features has been found in breast...

Fifth-generation (5G) technology is anticipated to allow a slew of novel applications across a variety of industries. The wireless communication of the 5G and Beyond-5G (B5G) networks will accommodate a wide variety of services and user expectations,...

Background and Aims: Lactose intolerance (LI) is a global problem affecting more than half of the world’s population. An ultra-purified, high-concentration galacto-oligosaccharide, RP-G28, is being developed as a treatment for patients with LI....

As the deployment of 5G mobile radio networks gains momentum across the globe, the wireless research community is already planning the successor of 5G. In this paper, we highlight the shortcomings of 5G in meeting the needs of more data-intensive, lo...

Tuberculosis (TB) has various clinical presentations; pulmonary TB (PTB) affects only the lungs, whereas extrapulmonary TB involves other organs, including pleural TB (PLTB). Immunological studies of patients with extrapulmonary TB primarily focus on...

In a prior issue of the Journal of Intelligence, I argued that the most important scientific issue in intelligence research was to identify specific abilities with validity beyond g (i.e., variance common to mental tests) (Coyle, T.R. Predictive vali...

Genomic DNA methylation is involved in many diseases and is expected to be a specific biomarker for even the pre-symptomatic diagnosis of many diseases. Thus, a rapid and inexpensive detection method is required for disease diagnosis. We have previou...

As many as 700,000 unique sequences in the human genome are predicted to fold into G-quadruplexes (G4s), non-canonical structures formed by Hoogsteen guanine–guanine pairing within G-rich nucleic acids. G4s play both physiological and pathologi...

The 3rd Generation Partnership Project (3GPP) evolution of mobile communication technologies from 5G to 6G has been a transformative journey spanning a decade, shaped by six releases from Release 15 to Release 20. This article provides a retrospectiv...

The coronavirus disease 2019 (COVID-19) pandemic has severely affected people’s lives worldwide in an unexpected manner. According to the World Health Organization (WHO), several viral epidemics continue to occur and pose a significant public h...

In this paper, emerging 5G mobile services are investigated and categorized from the perspective of not service providers, but end-users. The development of 5G mobile services is based on an intensive analysis of the global trends in mobile services....

The guanine base in nucleic acids is, among the other bases, the most susceptible to being converted into 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) when exposed to reactive oxygen species. In double-helix DNA, 8-oxodG can pair with adenine;...

Determining the position of ourselves or our assets has always been important to humans. Technology has helped us, from sextants to outdoor global positioning systems, but real-time indoor positioning has been a challenge. Among the various solutions...

Smart farming and precision agriculture rely on the different components of IoT, such as sensors, drones, and robotic devices. IoT in agriculture is the network of interconnected devices that corresponds in real time, simultaneously, to gather, analy...

This article provides an overview of the fifth generation of cellular communications (5G) and beyond. It presents the transmission techniques of current 5G communications and those expected of future developments, namely a brief study of non-orthogon...

This study investigates the impact of factors (network coverage, customer service, video calls, and downloading Speed) of 3G and 4G telecommunication services performance on customer satisfaction in the Punjab region of Pakistan. This research indica...

The Fifth generation (5G) network is projected to support large amount of data traffic and massive number of wireless connections. Different data traffic has different Quality of Service (QoS) requirements. 5G mobile network aims to address the limit...

The 5G cellular network comes with a promise to provide a very high data rate at low latency, which is becoming critical for advancing technologies. Mobile operators are currently deploying the 5G cellular network worldwide. However, because of limit...

Cytosine methylation within the 5′-C-phosphate-G-3′ sequence of nucleotides (called CpG methylation) is a well-known epigenetic modification of genomic DNA that plays an important role in gene expression and development. CpG methylation i...

This paper analyzes practical solutions for implementing 5G/6G and Digital Terrestrial Television (DTT) network coexistence in the UHF band. Two potential scenarios are explored using the case study of a nationwide DTT network: spectrum splitting and...

Engineering of fragment crystallizable (Fc) domains of therapeutic immunoglobulin (IgG) antibodies to eliminate their immune effector functions while retaining other Fc characteristics has numerous applications, including blocking antigens on Fc gamm...

Fifth-generation (5G) and sixth-generation (6G) wireless communications aim to achieve significantly higher data speeds, remarkably low latency, and substantial improvements in the efficiency of base stations. With the rapid increase in the utilizati...

This comment argues that an important issue in intelligence research is to identify constructs with validity beyond g, and that non-g residuals of tests represent a promising target.

The classification of services in 5G/B5G (Beyond 5G) networks has become important for telecommunications service providers, who face the challenge of simultaneously offering a better Quality of Service (QoS) in their networks and a better Quality of...

Pseudorabies, also known as Aujezsky’s disease, is an acute viral infection caused by pseudorabies virus (PRV). Swine are one of the natural hosts of pseudorabies and the disease causes huge economic losses in the pig industry. The establishmen...

Background: The differential diagnosis of immunoglobulin G4-sclerosing cholangitis (IgG4-SC) from primary sclerosing cholangitis (PSC) or cholangiocarcinoma (CCA) is important. In this study, we aimed to find the best combinations of serum IgG subcla...

The terahertz (THz) frequency bands are being explored as a potential means of enabling an ultra-high transmission capacity in sixth-generation (6G) radio-access networks (RAN) because higher frequencies offer broader bandwidths. When utilized in wir...

G-quadruplex (G4) oligonucleotides are higher-order DNA and RNA secondary structures of enormous relevance due to their implication in several biological processes and pathological states in different organisms. Strategies aiming at modulating human...

Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to i...

APOBEC3G (A3G) restricts HIV-1 replication primarily by reducing viral cDNA and inducing G-to-A hypermutations in viral cDNA. HIV-1 encodes virion infectivity factor (Vif) to counteract A3G primarily by excluding A3G viral encapsidation. Even though...

Mature B cells notably diversify immunoglobulin (Ig) production through class switch recombination (CSR), allowing the junction of distant “switch” (S) regions. CSR is initiated by activation-induced deaminase (AID), which targets cytosin...

Kaposi’s sarcoma herpesvirus (KSHV) is associated with a significant disease burden, in particular in Sub-Sahara Africa. A KSHV vaccine would be highly desirable, but the mechanisms underlying neutralizing antibody responses against KSHV remain...

G-quadruplexes are four-stranded nucleic acid structures occurring in the genomes of all living organisms and viruses. It is increasingly evident that these structures play important molecular roles; generally, by modulating gene expression and overa...

G-quadruplex (G4) structures are critical epigenetic regulatory elements, which usually form in guanine-rich regions in DNA. However, predicting the formation of G4 structures within living cells remains a challenge. Here, we present an ultra-robust...

The quantum leap in mobile data traffic and high density of wireless electronic devices, coupled with the advancements in industrial radio monitoring and autonomous systems, have created great challenges for smooth wireless network operations. The fi...

The 3rd generation partnership project (3GPP) has been enhancing the security of the 5G AKA (authentication and key agreement) protocol. However, there may still be some shortcomings in the latest version of the 5G AKA protocol. According to the anal...

Due to the rapid development of the fifth-generation (5G) applications, and increased demand for even faster communication networks, we expected to witness the birth of a new 6G technology within the next ten years. Many references suggested that the...

Background: Recently, based on HOMA-IR, we estimated empirical optimal cut-off values for SHBG levels of ≤41.5 nmol/L in women with PCOS. Other proposed markers of insulin resistance include triglyceride and glucose levels, and anthropometric meas...

5G acts as a highway enabling innovative digital transformation and the Fourth Industrial Revolution in our lives. It is undeniable that the success of such a paradigm shift hinges on robust security measures. Foremost among these is primary authenti...

DNA methylation is a major epigenetic mark with important roles in genetic regulation. Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non-CpG sites (CpA, CpT, and CpC). The general functions of CpG and non-CpG me...

In this paper, the $(G^{\prime }/G,1/G)$ -expansion method is applied to acquire some new, exact solutions of certain interesting, nonlinear, fractional-order partial differential equations arising in mathematical physics. The considered...

(1) Background: To analyze the association between long-term changes in serum IgG4 levels and the clinical course of patients with IgG4-related ophthalmic disease (IgG4-ROD). (2) Methods: Retrospective analysis of 25 patients with IgG4-ROD. (3) Resul...

5G, the fifth-generation mobile network, is predicted to significantly increase the traditional trajectory of energy consumption. It now uses four times as much energy as 4G, the fourth-generation mobile network. As a result, compared to previous gen...

In the evolving landscape of Industry 4.0, the integration of advanced wireless technologies into manufacturing processes holds the promise of unprecedented connectivity and efficiency. In particular, the data transmission in a heavy industry environ...

The transition from Fifth Generation (5G) New Radio (NR) systems to Beyond 5G (B5G) and Sixth Generation (6G) networks requires innovative architectures capable of supporting ultra-high data rates, sub-millisecond latency, and massive connection dens...

The deployment of the 5G mobile network is currently booming, offering commercially available services that improve network performance metrics by minimizing network latency in countries such as the USA, China, and Korea. However, many countries arou...

Next-generation communication systems and wearable technologies aim to achieve high data rates, low energy consumption, and massive connections because of the extensive increase in the number of Internet-of-Things (IoT) and wearable devices. These de...

This paper presents the functional expansion approach as a generalized method for finding traveling wave solutions of various nonlinear partial differential equations. The approach can be seen as a combination of the Kudryashov and $G^{\prime }/G$ solving...

Currently, 5G and the forthcoming 6G mobile communication systems are the most promising cellular generations expected to beat the growing hunger for bandwidth and enable the fully connected world presented by the Internet of Everything (IoE). The cl...

Guanine-rich sequences in the genomes of herpesviruses can fold into G-quadruplexes. Compared with the widely-studied G₃-quadruplexes, the dynamic G₂-quadruplexes are more sensitive to the cell microenvironment, but they attract less attention. Pseud...