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618 Results Found

  • Article
  • Open Access
10 Citations
2,859 Views
15 Pages

15 August 2021

Enterovirus A71 (EV-A71) is a major neurovirulent agent capable of causing severe hand, foot and mouth disease (HFMD) associated with neurological complications and death. Currently, no FDA-approved antiviral is available for the treatment of EV-A71...

  • Review
  • Open Access
26 Citations
7,505 Views
21 Pages

12 June 2018

Enterovirus 71 (EV-A71) is a major etiological agent of hand, foot and mouth disease (HFMD) that mainly affects young children less than five years old. The onset of severe HFMD is due to neurological complications bringing about acute flaccid paraly...

  • Systematic Review
  • Open Access
9 Citations
6,532 Views
13 Pages

Effectiveness of EV-A71 Vaccine and Its Impact on the Incidence of Hand, Foot and Mouth Disease: A Systematic Review

  • Quanman Hu,
  • Yaqi Xie,
  • Fucang Ji,
  • Fei Zhao,
  • Xiaoru Song,
  • Saiwei Lu,
  • Zijie Li,
  • Juan Geng,
  • Haiyan Yang and
  • Jinzhao Long
  • + 3 authors

8 September 2024

Background: Vaccination is a highly effective strategy for the prevention of enterovirus A71 (EV-A71)—hand, foot, and mouth disease (HFMD). Three inactivated EV-A71 vaccines in China have demonstrated remarkable efficacy against EV-A71-HFMD dur...

  • Article
  • Open Access
8 Citations
4,267 Views
25 Pages

Characterization of Plaque Variants and the Involvement of Quasi-Species in a Population of EV-A71

  • Madiiha Bibi Mandary,
  • Malihe Masomian,
  • Seng-Kai Ong and
  • Chit Laa Poh

17 June 2020

Viral plaque morphologies in human cell lines are markers for growth capability and they have been used to assess the viral fitness and selection of attenuated mutants for live-attenuated vaccine development. In this study, we investigate whether the...

  • Article
  • Open Access
389 Views
21 Pages

STING Restricts EV-A71 Infection by Regulating T Cell Development and Enhancing Immune Cell Effector Function

  • Huiqiang Wang,
  • Ya Wang,
  • Shuo Wu,
  • Lijun Qiao,
  • Wen Sheng,
  • Haiyan Yan,
  • Kun Wang,
  • Ge Yang,
  • Jiandong Jiang and
  • Yuhuan Li

26 November 2025

Previous studies have reported that Enterovirus A71 (EV-A71) infection could activate STING-related signaling pathways in vitro, but the role of STING in EV-A71 infection in vivo and the associated immune regulatory mechanisms remain unclear. Here, w...

  • Review
  • Open Access
501 Views
15 Pages

25 November 2025

Enterovirus A71 (EV-A71) is a critical global pathogen, primarily causing Hand-Foot-and-Mouth Disease (HFMD) but frequently leading to severe neurological complications, including fatal neurogenic pulmonary edema (PE). This review elucidates the comp...

  • Review
  • Open Access
168 Citations
17,962 Views
34 Pages

6 February 2020

Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped R...

  • Article
  • Open Access
20 Citations
4,142 Views
13 Pages

8 April 2020

Enterovirus A71 (EV-A71) is a major pathogen that causes severe and fatal cases of hand-foot-and-mouth disease (HFMD). HFMD caused by EV-A71 seriously endangers children’s health. Although autophagy is an important antiviral defense mechanism,...

  • Review
  • Open Access
15 Citations
6,226 Views
23 Pages

EV-A71 Mechanism of Entry: Receptors/Co-Receptors, Related Pathways and Inhibitors

  • Kanghong Hu,
  • Rominah Onintsoa Diarimalala,
  • Chenguang Yao,
  • Hanluo Li and
  • Yanhong Wei

18 March 2023

Enterovirus A71, a non-enveloped single-stranded (+) RNA virus, enters host cells through three stages: attachment, endocytosis and uncoating. In recent years, receptors/co-receptors anchored on the host cell membrane and involved in this process hav...

  • Article
  • Open Access
16 Citations
4,788 Views
14 Pages

15 August 2019

The compressive and flexural strengths of mortars modified with ethylene-vinyl acetate (EVA) were experimentally investigated for use in three-dimensional (3D) additive construction (3DAC). EVA powder, which is available in a premix type, was employe...

  • Article
  • Open Access
9 Citations
4,223 Views
16 Pages

31 October 2020

The contribution deals with the economic value added and its influence on credit absorption capacity. The aim was to determine the significance of the difference between the economic value added (EVA) entity and EVA equity indicators on credit absorp...

  • Article
  • Open Access
2,183 Views
17 Pages

Screening of Insertion Sites and Tags on EV-A71 VP1 Protein for Recombinant Virus Construction

  • Miaomiao Kang,
  • Xiangyi Li,
  • Xiaohong Li,
  • Rui Yu,
  • Shuo Zhang,
  • Jingjing Yan,
  • Xiaoyan Zhang,
  • Jianqing Xu,
  • Buyong Ma and
  • Shuye Zhang

17 January 2025

This study aimed to create a new recombinant virus by modifying the EV-A71 capsid protein, serving as a useful tool and model for studying human Enteroviruses. We developed a new screening method using EV-A71 pseudovirus particles to systematically i...

  • Article
  • Open Access
911 Views
13 Pages

Combined Antiviral and Cytoprotective Action of Rosmarinic Acid Against EV-A71 Infection: A Potential Therapeutic Strategy

  • Junping Lv,
  • Weishi Lin,
  • Siqi Chao,
  • Jing Xie,
  • Yue Cao,
  • Jinfeng Tie,
  • Yuehua Ke,
  • Binan Lu and
  • Zongran Pang

Enterovirus A71 (EV-A71), a major etiological agent of hand-foot-mouth disease, can cause severe neurological complications. However, the mechanisms underlying EV-A71-induced cell damage and potential therapeutic strategies remain inadequately unders...

  • Article
  • Open Access
10 Citations
3,715 Views
29 Pages

30 October 2021

Enterovirus 71 (EV-A71) is one of the predominant etiological agents of hand, foot and mouth disease (HMFD), which can cause severe central nervous system infections in young children. There is no clinically approved vaccine or antiviral agent agains...

  • Review
  • Open Access
7 Citations
3,264 Views
11 Pages

The Emerging Role of EVA1A in Different Types of Cancers

  • Huijie Zhao,
  • Huiyang Liu,
  • Yihan Yang and
  • Honggang Wang

Eva-1 homolog A (EVA1A), also known as transmembrane protein 166 (TMEM166) and regulator of programmed cell death, is an endoplasmic reticulum associated protein, which can play an important role in many diseases, including a variety of cancers, by r...

  • Article
  • Open Access
10 Citations
5,846 Views
14 Pages

Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery

  • Fatma Masmoudi,
  • Nanci Santos-Ferreira,
  • Dasja Pajkrt,
  • Katja C. Wolthers,
  • Jeroen DeGroot,
  • Maria L. H. Vlaming,
  • Joana Rocha-Pereira and
  • Ludovico Buti

12 April 2023

Enteroviruses are a leading cause of upper respiratory tract, gastrointestinal, and neurological infections. Management of enterovirus-related diseases has been hindered by the lack of specific antiviral treatment. The pre-clinical and clinical devel...

  • Review
  • Open Access
3 Citations
2,732 Views
22 Pages

Extravehicular activity (EVA) is a key point and a difficult point for manned spaceflight tasks, as well as an inevitable trend in the development of the manned spaceflight industry. Equipment maintenance, load installation, and extravehicular routin...

  • Article
  • Open Access
11 Citations
3,168 Views
13 Pages

The Genetic Background of Hearing Loss in Patients with EVA and Cochlear Malformation

  • Natalia Bałdyga,
  • Dominika Oziębło,
  • Nina Gan,
  • Mariusz Furmanek,
  • Marcin L. Leja,
  • Henryk Skarżyński and
  • Monika Ołdak

28 January 2023

The most frequently observed congenital inner ear malformation is enlarged vestibular aqueduct (EVA). It is often accompanied with incomplete partition type 2 (IP2) of the cochlea and a dilated vestibule, which together constitute Mondini malformatio...

  • Article
  • Open Access
5 Citations
3,910 Views
11 Pages

18 July 2019

In this study, the fresh properties of ethylene–vinyl acetate (EVA)-modified cementitious mixtures were experimentally investigated to evaluate the feasibility of this type of material being used in additive construction by extrusion (ACE). The...

  • Article
  • Open Access
6 Citations
3,270 Views
15 Pages

8 October 2019

This study experimentally examined the deformability of cementitious mortars modified with ethylene-vinyl acetate (EVA) for use in extrusion-based additive construction. The research was based on the author’s previous study of the properties of...

  • Review
  • Open Access
14 Citations
3,502 Views
12 Pages

Eva-1 homolog A (EVA1A) is regarded as TMEM166 (transmembrane protein 166) or FAM176A (family with sequence similarity 176) and a lysosome and endoplasmic reticulum-associated protein involved in regulating autophagy and apoptosis. EVA1A regulates em...

  • Article
  • Open Access
28 Citations
3,622 Views
24 Pages

Comparing Multi-Walled Carbon Nanotubes and Halloysite Nanotubes as Reinforcements in EVA Nanocomposites

  • Agata Zubkiewicz,
  • Anna Szymczyk,
  • Piotr Franciszczak,
  • Agnieszka Kochmanska,
  • Izabela Janowska and
  • Sandra Paszkiewicz

28 August 2020

The influence of carbon multi-walled nanotubes (MWCNTs) and halloysite nanotubes (HNTs) on the physical, thermal, mechanical, and electrical properties of EVA (ethylene vinyl acetate) copolymer was investigated. EVA-based nanocomposites containing MW...

  • Article
  • Open Access
13 Citations
5,167 Views
12 Pages

Fabrication of Dielectric Elastomer Composites by Locking a Pre-Stretched Fibrous TPU Network in EVA

  • Liang Jiang,
  • Yanfen Zhou,
  • Yuhao Wang,
  • Zhiqing Jiang,
  • Fang Zhou,
  • Shaojuan Chen and
  • Jianwei Ma

12 September 2018

Dielectric elastomer (DE) composites with high electrical breakdown strength and large voltage-induced deformation were developed by retaining pre-stretched thermoplastic polyurethane (TPU) fibers in ethylene vinyl acetate copolymer (EVA). The micros...

  • Article
  • Open Access
16 Citations
5,352 Views
16 Pages

Ethylene-Vinyl Acetate (EVA) Containing Waste Hemp-Derived Biochar Fibers: Mechanical, Electrical, Thermal and Tribological Behavior

  • Maria Giulia Faga,
  • Donatella Duraccio,
  • Mattia Di Maro,
  • Riccardo Pedraza,
  • Mattia Bartoli,
  • Giovanna Gomez d’Ayala,
  • Daniele Torsello,
  • Gianluca Ghigo and
  • Giulio Malucelli

4 October 2022

To reduce the use of carbon components sourced from fossil fuels, hemp fibers were pyrolyzed and utilized as filler to prepare EVA-based composites for automotive applications. The mechanical, tribological, electrical (DC and AC) and thermal properti...

  • Article
  • Open Access
17 Citations
5,850 Views
19 Pages

Influence of Lamination Conditions of EVA Encapsulation on Photovoltaic Module Durability

  • Dan Wu,
  • Patrick Wessel,
  • Jiang Zhu,
  • Daniel Montiel-Chicharro,
  • Thomas R. Betts,
  • Anton Mordvinkin and
  • Ralph Gottschalg

29 October 2023

Encapsulation is a well-known impact factor on the durability of Photovoltaics (PV) modules. Currently there is a lack of understanding on the relationship between lamination process and module durability. In this paper, the effects of different lami...

  • Article
  • Open Access
3 Citations
2,454 Views
13 Pages

14 October 2022

The hand-transmitted vibration generated by extravehicular activity (EVA) power tools has an important impact on the health of astronauts and the efficient completion of maintenance tasks when astronauts use EVA power tools for on-orbit maintenance....

  • Article
  • Open Access
22 Citations
5,952 Views
10 Pages

25 November 2021

In order to improve the bonding performance, EVA composite hot melt adhesives were prepared by introducing crosslinking agent and silane coupling agent in this paper. A binary EVA resin blend as the base resin with appropriate viscosity and tensile s...

  • Article
  • Open Access
19 Citations
2,612 Views
12 Pages

3D-Printed EVA Devices for Antiviral Delivery and Herpes Virus Control in Genital Infection

  • Victor de Carvalho Rodrigues,
  • Iara Zanella Guterres,
  • Beatriz Pereira Savi,
  • Izabella Thaís Silva,
  • Gislaine Fongaro and
  • Gean Vitor Salmoria

11 November 2022

Herpes viruses are widespread in the human population and can cause many different diseases. Genital herpes is common and can increase the risk of HIV infection and neonatal herpes. Acyclovir is the most used drug for herpes treatment; however, it pr...

  • Article
  • Open Access
21 Citations
7,669 Views
20 Pages

Preparation, Characterization and Thermo-Chromic Properties of EVA/VO2 Laminate Films for Smart Window Applications and Energy Efficiency in Building

  • Onruthai Srirodpai,
  • Jatuphorn Wootthikanokkhan,
  • Saiwan Nawalertpanya,
  • Kitti Yuwawech and
  • Vissanu Meeyoo

11 January 2017

Thermochromic films based on vanadium dioxide (VO2)/ethylene vinyl acetate copolymer (EVA) composite were developed. The monoclinic VO2 particles was firstly prepared via hydrothermal and calcination processes. The effects of hydrothermal time and tu...

  • Article
  • Open Access
2,916 Views
15 Pages

EVA Films Loaded with Layered Double Hydroxide (LDH) Modified with Methacrylic Anion: Effect of the Nanohybrid Filler on the Photodegradation Phenomena

  • Giuliana Gorrasi,
  • Gianluca Viscusi,
  • Giusy Curcuruto,
  • Maria Cantarella,
  • Alessandro Di Mauro,
  • Paola Bernardo,
  • Gabriele Clarizia,
  • Andrea A. Scamporrino and
  • Sabrina Carroccio

30 July 2021

The photo-oxidative studies of ethylene vinyl acetate copolymer (EVA) matrix, filled with Layered Double Hydroxide (LDH) modified with methacrylic anion (MA), were herein reported, together with gas permeation tests. The formulation of nano-hybrid LD...

  • Article
  • Open Access
11 Citations
9,880 Views
19 Pages

Performance Management for Growth: A Framework Based on EVA

  • Mihaela Brindusa Tudose,
  • Valentina Diana Rusu and
  • Silvia Avasilcai

Some of the constructs in the field of performance management are intuitive or not empirically validated. This study provides a data-driven framework for measuring and improving the performance through synchronized strategies. The ultimate goal was t...

  • Article
  • Open Access
9 Citations
3,169 Views
11 Pages

Fabrication of Color Glass by Pearlescent Pigments and Dissolved EVA Film

  • Seongmin Lim,
  • Hyeon-Sik Ahn,
  • Akpeko Gasonoo,
  • Jae-Hyun Lee and
  • Yoonseuk Choi

13 August 2022

In this paper, we propose a single-layer thin-film color glass manufacturing process for building-integrated photovoltaics (BIPV) with excellent aesthetics and high transmittance, through a solution process using pearlescent pigments. As a matrix for...

  • Article
  • Open Access
756 Views
17 Pages

Flame-Retardant Properties of a Styrene-Vinyl Tetrazole Copolymer Additive in an LDPE/EVA Blend

  • Karla Fabiola Rodríguez Ramírez,
  • Jesús Francisco Lara Sánchez,
  • Orlando Castro Reyna,
  • Pedro Espinoza Martínez,
  • Jesús Alejandro Espinosa Muñoz,
  • José David Zuluaga Parra,
  • Rachel Faverzani Magnago,
  • Saul Sanchez Valdés and
  • Luciano da Silva

31 October 2025

In this work, we report the effect of combining styrene-vinyl tetrazole copolymer (StVTz) and ammonium polyphosphate (APP) on the thermal degradation, mechanical properties, flame retardancy, and char formation of low-density polyethylene with ethyl...

  • Feature Paper
  • Article
  • Open Access
25 Citations
4,129 Views
16 Pages

Improving Mechanical Properties and Reaction to Fire of EVA/LLDPE Blends for Cable Applications with Melamine Triazine and Bentonite Clay

  • Guadalupe Sanchez-Olivares,
  • Antonio Sanchez-Solis,
  • Octavio Manero,
  • Ricardo Pérez-Chávez,
  • Mario Jaramillo,
  • Jenny Alongi and
  • Federico Carosio

26 July 2019

The high flame-retardant loading required for ethylene-vinyl acetate copolymer blends with polyethylene (EVA-PE) employed for insulation and sheathing of electric cables represents a significant limitation in processability and final mechanical prope...

  • Article
  • Open Access
23 Citations
4,739 Views
12 Pages

4 April 2022

The calcium hydroxide (Ca(OH)2) content is one of the main indices of cement hydration degree. In order to accurately determine the calcium hydroxide content of ethylene and vinyl acetate (EVA) copolymer-modified cement paste, a dual atmosphere therm...

  • Article
  • Open Access
14 Citations
3,118 Views
14 Pages

5 August 2023

The ladder phenyl/vinyl polysilsesquioxane (PhVPOSS) was used to improve the flame-retardancy performances of ethylene-vinyl acetate copolymer (EVA)/aluminum hydroxide (ATH) composites due to the reactivity of its vinyl groups. FTIR, XPS, 1H NMR, and...

  • Article
  • Open Access
12 Citations
4,711 Views
13 Pages

13 April 2021

The notable photophysical characteristics of perovskite quantum dots (PQDs) (CsPbBr3) are suitable for optoelectronic devices. However, the performance of PQDs is unstable because of their surface defects. One way to address the instability is to pas...

  • Article
  • Open Access
3 Citations
2,428 Views
29 Pages

The Financial Risk Measurement EVaR Based on DTARCH Models

  • Xiaoqian Liu,
  • Zhenni Tan,
  • Yuehua Wu and
  • Yong Zhou

13 August 2023

The value at risk based on expectile (EVaR) is a very useful method to measure financial risk, especially in measuring extreme financial risk. The double-threshold autoregressive conditional heteroscedastic (DTARCH) model is a valuable tool in assess...

  • Article
  • Open Access
3 Citations
2,139 Views
13 Pages

Preparation of Antimony-Doped Tin Oxide Fly Ash Antistatic Composite and Its Properties in Filling EVA

  • Ying Qiu,
  • Caili Wang,
  • Chunxue Zhao,
  • Guoxin Yao,
  • Zhixue Wang and
  • Runquan Yang

3 March 2024

As a common coal-based solid waste, fly ash is widely used in material filling. However, due to the high resistivity of fly ash itself, the antistatic performance of the filling material is poor. Therefore, antistatic composite powder was prepared by...

  • Article
  • Open Access
1 Citations
1,993 Views
15 Pages

Flexible Positive Temperature Coefficient Composites (PVAc/EVA/GP-CNF) with Room Temperature Curie Point

  • Chao Du,
  • Yangyang Zhang,
  • Jiangmin Lin,
  • Guotao Fan,
  • Can Zhou and
  • Yan Yu

16 July 2024

Polymeric positive temperature coefficient (PTC) materials with low switching temperature points are crucial for numerous electronic devices, which typically function within the room temperature range (0–40 °C). Ideal polymeric PTC material...

  • Article
  • Open Access
747 Views
24 Pages

Effect of Antimicrobial Filler on Ethylene-Vinyl Acetate (EVA) Composites Property

  • Kamil Kwieciński,
  • Marta Chrószcz-Porębska,
  • Izabela Barszczewska-Rybarek,
  • Jarosław Żmudzki,
  • Anna Mertas,
  • Sebastian Jurczyk,
  • Paweł Popielski and
  • Grzegorz Chladek

31 October 2025

Ethylene–vinyl acetate (EVA) is a versatile polymer for applications in dental devices; however, its vulnerability to microbial colonization increases with long-term use. This study evaluates EVA composites modified with silver–sodium&nda...

  • Article
  • Open Access
3 Citations
5,917 Views
11 Pages

Development of a Melting Curve-Based Triple Eva Green Real-Time PCR Assay for Simultaneous Detection of Three Shrimp Pathogens

  • Xuan Dong,
  • Yujin Chen,
  • Haoyu Lou,
  • Guohao Wang,
  • Chengyan Zhou,
  • Liying Wang,
  • Xuan Li,
  • Jingfei Luo and
  • Jie Huang

11 February 2024

Infections with Enterocytozoon hepatopenaei (EHP), infectious hypodermal and hematopoietic necrosis virus (IHHNV), and Decapod iridescent virus 1 (DIV1) pose significant challenges to the shrimp industry. Here, a melting curve-based triple real-time...

  • Article
  • Open Access
10 Citations
4,184 Views
19 Pages

4 November 2020

Evapotranspiration (ET) has a decisive effect on groundwater recharge and thus also affects the base flow of the receiving water. This applies above all to low-lying areas with a low depth to groundwater (GW), as is often the case in the north German...

  • Article
  • Open Access
3 Citations
2,241 Views
12 Pages

26 April 2022

The objective of this paper is to accurately measure the vibration response of tools and hands by simulating the hand-held power tools, which are operated by astronauts wearing extravehicular spacesuit gloves under microgravity conditions. The total...

  • Article
  • Open Access
1 Citations
479 Views
22 Pages

16 November 2025

The contamination of water by heavy metals is a global problem with distressing health consequences, and researchers have proposed various methods to remove these ions. This study explored poly (lactic acid) (PLA)/ethylene vinyl acetate (EVA)/graphen...

  • Article
  • Open Access
8 Citations
4,252 Views
17 Pages

Analysis of SLC26A4, FOXI1, and KCNJ10 Gene Variants in Patients with Incomplete Partition of the Cochlea and Enlarged Vestibular Aqueduct (EVA) Anomalies

  • Leonid A. Klarov,
  • Vera G. Pshennikova,
  • Georgii P. Romanov,
  • Aleksandra M. Cherdonova,
  • Aisen V. Solovyev,
  • Fedor M. Teryutin,
  • Nikolay V. Luginov,
  • Petr M. Kotlyarov and
  • Nikolay A. Barashkov

6 December 2022

Pathogenic variants in the SLC26A4, FOXI1, and KCNJ10 genes are associated with hearing loss (HL) and specific inner ear abnormalities (DFNB4). In the present study, phenotype analyses, including clinical data collection, computed tomography (CT), an...

  • Article
  • Open Access
16 Citations
5,441 Views
15 Pages

8 February 2024

Photovoltaic (PV) modules are highly efficient power generators associated with solar energy. The rapid growth of the PV industry will lead to a sharp increase in the waste generated from PV panels. However, electro-waste can be successfully used as...

  • Article
  • Open Access
6 Citations
2,780 Views
17 Pages

7 December 2020

This study analyzes the optimal seasonal ambient temperature during welding and welding speed conditions for securing high tensile strength of ethylene vinyl acetate (EVA) waterproofing sheets bonded for roofing, installed by hot air welded joints (o...

  • Article
  • Open Access
12 Citations
3,548 Views
23 Pages

19 January 2023

Because of their high filler loadings, commercial-grade clean flame-retardant materials have unstable mechanical properties. To address this issue, intumescent polymers can be used to develop clean flame retardants with very low levels of smoke and t...

  • Review
  • Open Access
1 Citations
2,555 Views
9 Pages

27 June 2024

Background: Enlarged vestibular aqueduct (EVA) syndrome can mimic otosclerosis in adults, presenting with an air–bone gap (ABG) and even absent stapedial reflexes. The ABG in inner-ear disorders is currently the object of several authors’...

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