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19 Results Found

  • Article
  • Open Access
1,187 Views
16 Pages

26 December 2024

Chlormequat chloride (CCC) has been demonstrated to inhibit plant growth and strengthen seedlings. The present study demonstrated that the root growth of Thompson seedless grapevine seedlings was significantly enhanced by the application of CCC treat...

  • Article
  • Open Access
5 Citations
2,838 Views
14 Pages

Phenotypic and Phylogenetic Characterization of Cu Homeostasis among Xylella fastidiosa Strains

  • Qing Ge,
  • Ranlin Liu,
  • Paul A. Cobine,
  • Neha Potnis and
  • Leonardo De La Fuente

Xylella fastidiosa is a bacterial pathogen causing severe diseases and asymptomatic colonization in more than 600 plants worldwide. Copper (Cu) is a widely used antimicrobial treatment for various plant diseases, including those affecting X. fastidio...

  • Article
  • Open Access
14 Citations
3,549 Views
16 Pages

21 December 2022

As an essential element in plant nutrition, copper (Cu) can promote or inhibit plant growth depending on its concentration. However, the dose-dependent effects of copper, particularly on DNA damage associated with reactive oxygen species (ROS) homeos...

  • Article
  • Open Access
4 Citations
2,505 Views
16 Pages

22 May 2023

Fruit nutritional value, plant growth, and yield can be compromised by deficient copper (Cu) bioavailability, which often appears in arable lands. This condition causes low Cu content and modifications in the ripening-associated processes in tomato f...

  • Article
  • Open Access
957 Views
20 Pages

Meta-Transcriptomic Response to Copper Corrosion in Drinking Water Biofilms

  • Jingrang Lu,
  • Ian Struewing and
  • Nicholas J. Ashbolt

Drinking water biofilm ecosystems harbor complex and dynamic prokaryotic and eukaryotic microbial communities. However, little is known about the impact of copper corrosion on microbial community functions in metabolisms and resistance. This study wa...

  • Article
  • Open Access
20 Citations
3,932 Views
15 Pages

Molecular Characterization, Protein–Protein Interaction Network, and Evolution of Four Glutathione Peroxidases from Tetrahymena thermophila

  • Diana Ferro,
  • Rigers Bakiu,
  • Sandra Pucciarelli,
  • Cristina Miceli,
  • Adriana Vallesi,
  • Paola Irato and
  • Gianfranco Santovito

2 October 2020

Glutathione peroxidases (GPxs) form a broad family of antioxidant proteins essential for maintaining redox homeostasis in eukaryotic cells. In this study, we used an integrative approach that combines bioinformatics, molecular biology, and biochemist...

  • Article
  • Open Access
7 Citations
2,961 Views
20 Pages

5 April 2024

The contamination of aquatic ecosystems by the heavy metal copper (Cu) is an important environmental issue and poses significant risks to the physiological functions of aquatic organisms. Macrobrachium rosenbergii is one of the most important freshwa...

  • Article
  • Open Access
5 Citations
5,557 Views
24 Pages

This study was aimed at evaluating the changes in metallothionein (MT) concentration in the blood of patients with acute pancreatitis (AP) and healthy subjects, taking into account the extracellular (plasma) and intracellular (erythrocyte lysate) com...

  • Article
  • Open Access
1 Citations
3,204 Views
21 Pages

20 December 2024

Combining anti-cancer agents in cancer therapies is becoming increasingly common because of their improved efficacy, reduced toxicity, and decreased risk of resistance development. Melanoma, a highly aggressive form of skin cancer characterized by li...

  • Article
  • Open Access
7 Citations
2,835 Views
23 Pages

5 September 2023

Background: The liver plays an important role in maintaining copper homeostasis. Copper ion accumulation was elevated in HCC tissue samples. Copper homeostasis is implicated in cancer cell proliferation and angiogenesis. The potential of copper homeo...

  • Article
  • Open Access
5 Citations
2,377 Views
20 Pages

18 February 2025

Prenatal exposure to metals can influence fetal programming via DNA methylation and has been linked to adverse birth outcomes and long-term consequences. Epigenetic clocks estimate the biological age of a given tissue based on DNA methylation and are...

  • Article
  • Open Access
10 Citations
2,605 Views
15 Pages

The Drug H+ Antiporter FgQdr2 Is Essential for Multiple Drug Resistance, Ion Homeostasis, and Pathogenicity in Fusarium graminearum

  • Tianling Ma,
  • Yiqing Li,
  • Yang Lou,
  • Junrui Shi,
  • Kewei Sun,
  • Zhonghua Ma,
  • Leiyan Yan and
  • Yanni Yin

26 September 2022

Increased emergence of drug resistance and DON pollution pose a severe problem in Fusarium head blight (FHB) control. While the H+ antiporter (DHA) family plays crucial roles in drug resistance, the characterization of DHA transporters has not been s...

  • Article
  • Open Access
724 Views
20 Pages

18 July 2025

Copper pyrithione (CuPT), an emerging biocide used in ship antifouling coatings, may accumulate in marine sediments and pose risks to non-target organisms. However, current research on CuPT toxicity remains limited. Litopenaeus vannamei, one of the w...

  • Article
  • Open Access
5 Citations
1,849 Views
23 Pages

Regulatory Mechanism through Which Old Soybean Leaves Respond to Mn Toxicity Stress

  • Yuhu Pan,
  • Jianning Shi,
  • Jianyu Li,
  • Rui Zhang,
  • Yingbin Xue and
  • Ying Liu

Manganese (Mn) is a heavy metal that can cause excessive Mn poisoning in plants, disrupting microstructural homeostasis and impairing growth and development. However, the specific response mechanisms of leaves to Mn poisoning have not been fully eluc...

  • Review
  • Open Access
99 Citations
12,746 Views
55 Pages

Consequences of Disturbing Manganese Homeostasis

  • Jacek Baj,
  • Wojciech Flieger,
  • Aleksandra Barbachowska,
  • Beata Kowalska,
  • Michał Flieger,
  • Alicja Forma,
  • Grzegorz Teresiński,
  • Piero Portincasa,
  • Grzegorz Buszewicz and
  • Elżbieta Radzikowska-Büchner
  • + 1 author

6 October 2023

Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant enzyme systems, neurotransmitter production, and the regulation of reprod...

  • Article
  • Open Access
38 Citations
6,938 Views
30 Pages

18 October 2020

Liquid-liquid phase separation (LLPS) is a rapidly growing research focus due to numerous demonstrations that many cellular proteins phase-separate to form biomolecular condensates (BMCs) that nucleate membraneless organelles (MLOs). A growing repert...

  • Article
  • Open Access
3 Citations
2,288 Views
19 Pages

Functional Association between Storage Protein Mobilization and Redox Signaling in Narrow-Leafed Lupin (Lupinus angustifolius L.) Seed Germination and Seedling Development

  • Julia Escudero-Feliu,
  • Elena Lima-Cabello,
  • Esther Rodríguez de Haro,
  • Sonia Morales-Santana and
  • Jose C. Jimenez-Lopez

28 September 2023

(1) Background: Seed storage mobilization, together with oxidative metabolism, with the ascorbate–glutathione (AsA-GSH) cycle as a crucial signaling and metabolic functional crossroad, is one of the main regulators of the control of cell morpho...

  • Article
  • Open Access
822 Views
23 Pages

4 September 2025

The tall wheatgrass Thinopyrum ponticum has excellent saline–alkali tolerance and great potential for restoring saline–alkali land to enhance productivity. This study used the Thinopyrum ponticum cv. “Orbit” variety, which is...

  • Article
  • Open Access
3 Citations
1,879 Views
20 Pages

Rhizofungus Aspergillus terreus Mitigates Heavy Metal Stress-Associated Damage in Triticum aestivum L.

  • Naveen Dilawar,
  • Muhammad Hamayun,
  • Amjad Iqbal,
  • Bokyung Lee,
  • Sajid Ali,
  • Ayaz Ahmad,
  • Abdulwahed Fahad Alrefaei,
  • Turki Kh. Faraj,
  • Ho-Youn Kim and
  • Anwar Hussain

21 September 2024

Industrial waste and sewage deposit heavy metals into the soil, where they can remain for long periods. Although there are several methods to manage heavy metals in agricultural soil, microorganisms present a promising and effective solution for thei...