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453 Results Found

  • Article
  • Open Access
34 Citations
4,518 Views
13 Pages

NO Candida auris: Nitric Oxide in Nanotherapeutics to Combat Emerging Fungal Pathogen Candida auris

  • Levi G. Cleare,
  • Kevin L. Li,
  • Waleed M. Abuzeid,
  • Parimala Nacharaju and ,
  • Joel M. Friedman and
  • Joshua D. Nosanchuk
  • + 1 author+ 0 author

12 June 2020

Candida auris (C. auris) is an emerging pathogenic fungal species that is especially worrisome due to its high mortality rates and widespread antifungal resistance. Previous studies have demonstrated the efficacy of nitric oxide (NO) nanoparticles on...

  • Article
  • Open Access
37 Citations
13,259 Views
9 Pages

Candida auris in Dog Ears

  • Anamika Yadav,
  • Yue Wang,
  • Kusum Jain,
  • Vijay Amrit Raj Panwar and ,
  • Hardeep Kaur,
  • Vikas Kasana,
  • Jianping Xu and
  • Anuradha Chowdhary
  • + 3 authors+ 0 author

30 June 2023

Candida auris is an emerging global public health threat and is resistant to most antifungal agents. Though fungi are significant pathogens for animals, the role of C. auris in animal health remains unexplored. Here, we analysed the microbial culture...

(This article belongs to the Special Issue Multidrug-Resistant Fungi)
  • Article
  • Open Access
30 Citations
6,038 Views
7 Pages

Comparison of Two Commercially Available qPCR Kits for the Detection of Candida auris

  • Janko Sattler,
  • Janina Noster,
  • Anne Brunke,
  • Georg Plum and ,
  • Pia Wiegel,
  • Oliver Kurzai,
  • Jacques F. Meis and
  • Axel Hamprecht
  • + 3 authors+ 0 author

22 February 2021

Candida auris is an emerging pathogen with resistance to many commonly used antifungal agents. Infections with C. auris require rapid and reliable detection methods to initiate successful medical treatment and contain hospital outbreaks. Conventional...

(This article belongs to the Special Issue Candida auris 2.0)
  • Article
  • Open Access
587 Views
12 Pages

Fluconazole Disk Diffusion on CHROMagar Candida Plus for Differentiation Between Candidozyma auris and Candida parapsilosis

  • Sarah Israel,
  • Jonathan Lellouche,
  • Loujin Ardda,
  • Ariel Israel and ,
  • Sharon Amit,
  • Ronen Ben-Ami,
  • Itzhack Polacheck,
  • Jacob Moran-Gilad and
  • Maya Korem
  • + 4 authors+ 0 author

13 August 2026

Background: This study evaluated the utility of fluconazole disk diffusion on CHROMagar Candida Plus for differentiating Candidozyma auris from Candida parapsilosis. Methods: In this in vitro study, clinical isolates of both C. auris and C. parapsilo...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Review
  • Open Access
101 Citations
10,449 Views
14 Pages

An Overview on Candida auris in Healthcare Settings

  • Maria Luisa Cristina,
  • Anna Maria Spagnolo,
  • Marina Sartini,
  • Alessio Carbone and ,
  • Martino Oliva,
  • Elisa Schinca,
  • Silvia Boni and
  • Emanuele Pontali
  • + 3 authors+ 0 author

8 September 2023

Candida auris has become a major concern in critical care medicine due to the increasing number of immunocompromised patients and candidiasis is the most frequent cause of fungal infections. C. auris and other fungal pathogens are responsible for at...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Article
  • Open Access
18 Citations
2,687 Views
16 Pages

Candida auris vs. Non-Candida auris Candidemia in Critically Ill Patients: Clinical Outcomes, Risk Factors, and Mortality

  • Ezgi Gülten,
  • Güle Çınar,
  • Elif Mukime Sarıcaoğlu,
  • İrem Akdemir and ,
  • Afife Zeynep Yılmaz,
  • Elif Hilal Saldere and
  • Fügen Yörük
  • + 2 authors+ 0 author

24 July 2025

Background:Candida auris (now Candidozyma auris) is an emerging pathogen that causes nosocomial candidemia, particularly in intensive care unit (ICU) settings. Its high resistance rates, prolonged environmental persistence, and outbreak potential und...

  • Communication
  • Open Access
10 Citations
10,952 Views
9 Pages

Usefulness of Chromogenic Media with Fluconazole Supplementation for Presumptive Identification of Candida auris

  • Alba Ruiz-Gaitán,
  • Ignacio Sigona-Giangreco,
  • José Manuel Pérez-Royo,
  • Victor Garcia-Bustos and ,
  • Marta García-Hita,
  • Eulogio Valentín-Gómez,
  • Salvador Giner Almaraz,
  • Piet W. J. de Groot and
  • Javier Pemán
  • + 4 authors+ 0 author

Introduction:Candida auris is a major threat to public health. Rapid detection is essential for early treatment and transmission control. The use of chromogenic media allows the presumptive identification of this new species. The aim of this study is...

(This article belongs to the Special Issue Advances in Fungal Infections: Special Issue in Diagnostics Journal-Volume 2)
  • Article
  • Open Access
18 Citations
5,680 Views
14 Pages

Thermogenic Characterization and Antifungal Susceptibility of Candida auris by Microcalorimetry

  • Mariagrazia Di Luca,
  • Anna Koliszak,
  • Svetlana Karbysheva,
  • Anuradha Chowdhary and ,
  • Jacques F. Meis and
  • Andrej Trampuz
  • + 1 author+ 0 author

6 November 2019

Candida auris has emerged globally as a multidrug-resistant fungal pathogen. Isolates of C. auris are reported to be misidentified as Candida haemulonii. The aim of the study was to compare the heat production profiles of C. auris strains and other C...

(This article belongs to the Special Issue Candida auris)
  • Review
  • Open Access
54 Citations
12,330 Views
17 Pages

Candida auris: A Continuing Threat

  • Ashish Bhargava,
  • Katherine Klamer,
  • Mamta Sharma,
  • Daniel Ortiz and
  • Louis Saravolatz

Candida auris is a World Health Organization critical-priority fungal pathogen that has variable resistance to antifungal treatments. Multiple clades have been identified through genomic analysis and have appeared in different geographic locations si...

(This article belongs to the Special Issue Current Pattern in Epidemiology and Antifungal Resistance)
  • Article
  • Open Access
16 Citations
3,882 Views
15 Pages

In Vitro Antifungal Activity of Three Synthetic Peptides against Candida auris and Other Candida Species of Medical Importance

  • Richar Torres,
  • Adriana Barreto-Santamaría,
  • Gabriela Arévalo-Pinzón,
  • Carolina Firacative and ,
  • Beatriz L. Gómez,
  • Patricia Escandón,
  • Manuel Alfonso Patarroyo and
  • Julián E. Muñoz
  • + 3 authors+ 0 author

Candidiasis is an opportunistic infection affecting immunosuppressed and hospitalized patients, with mortality rates approaching 40% in Colombia. The growing pharmacological resistance of Candida species and the emergence of multidrug-resistant Candi...

(This article belongs to the Special Issue The Century-Long Journey of Peptide-Based Drugs)
  • Review
  • Open Access
32 Citations
9,582 Views
11 Pages

7 November 2024

Candida auris (C. auris) has emerged as a fungal pathogen with great propensity to spread rapidly on a global scale. C. auris infections have also caused significant morbidity and mortality. Strategies to prevent spread and outbreaks are critical. In...

(This article belongs to the Section Epidemiology & Public Health)
  • Case Report
  • Open Access
30 Citations
6,596 Views
7 Pages

The First Two Cases of Candida auris in The Netherlands

  • Erik H. Vogelzang,
  • Annemarie J.L. Weersink,
  • Rosa van Mansfeld,
  • Nancy A. Chow and ,
  • Jacques F. Meis and
  • Karin van Dijk
  • + 1 author+ 0 author

30 September 2019

Candida auris is a rapidly emerging multidrug-resistant pathogenic yeast. In recent years, an increasing number of C. auris invasive infections and colonized patients have been reported, and C. auris has been associated with hospital outbreaks worldw...

(This article belongs to the Special Issue Candida auris)
  • Article
  • Open Access
48 Citations
10,953 Views
10 Pages

Antifungal Activity of a Medical-Grade Honey Formulation against Candida auris

  • Theun de Groot,
  • Tom Janssen,
  • Dirk Faro,
  • Niels A. J. Cremers and ,
  • Anuradha Chowdhary and
  • Jacques F. Meis
  • + 1 author+ 0 author

13 January 2021

Candida auris is a pathogenic yeast causing outbreaks in intensive care units with high mortality rates. The treatment of C. auris colonization is challenging due to high resistance rates. A potential alternative antifungal treatment is medical-grade...

(This article belongs to the Special Issue Candida auris 2.0)
  • Article
  • Open Access
43 Citations
6,362 Views
10 Pages

Mortality Caused by Candida auris Bloodstream Infections in Comparison with Other Candida Species, a Multicentre Retrospective Cohort

  • Cynthia Ortiz-Roa,
  • Martha Carolina Valderrama-Rios,
  • Sebastián Felipe Sierra-Umaña,
  • José Yesid Rodríguez and ,
  • Gerardo Antonio Muñetón-López,
  • Carlos Augusto Solórzano-Ramos,
  • Patricia Escandón,
  • Carlos Arturo Alvarez-Moreno and
  • Jorge Alberto Cortés
  • + 4 authors+ 0 author

29 June 2023

Candida auris is an emerging pathogen considered to be critical in the World Health Organization fungal organisms list. The study aims to determine the mortality and hospital stays attributed to Candida auris (C. auris) compared to other Candida spec...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Perspective
  • Open Access
154 Citations
30,808 Views
17 Pages

On the Origins of a Species: What Might Explain the Rise of Candida auris?

  • Brendan R. Jackson,
  • Nancy Chow,
  • Kaitlin Forsberg,
  • Anastasia P. Litvintseva and ,
  • Shawn R. Lockhart,
  • Rory Welsh,
  • Snigdha Vallabhaneni and
  • Tom Chiller
  • + 3 authors+ 0 author

6 July 2019

Candida auris is an emerging multidrug-resistant yeast first described in 2009 that has since caused healthcare-associated outbreaks of severe human infections around the world. In some hospitals, it has become a leading cause of invasive candidiasis...

(This article belongs to the Special Issue Candida auris)
  • Article
  • Open Access
18 Citations
5,567 Views
8 Pages

Hospital Laboratory Survey for Identification of Candida auris in Belgium

  • Klaas Dewaele,
  • Katrien Lagrou,
  • Johan Frans,
  • Marie-Pierre Hayette and
  • Kris Vernelen

5 September 2019

Candida auris is a difficult-to-identify, emerging yeast and a cause of sustained nosocomial outbreaks. Presently, not much data exist on laboratory preparedness in Europe. To assess the ability of laboratories in Belgium and Luxembourg to detect thi...

(This article belongs to the Special Issue Candida auris)
  • Article
  • Open Access
1 Citations
1,161 Views
18 Pages

Evaluation of the Ca37 Monoclonal Antibody Targeting Alcohol Dehydrogenase Against Candidozyma auris (Candida auris) In Vitro and In Vivo

  • Oier Rodriguez-Erenaga,
  • Maialen Areitio,
  • Lucia Abio-Dorronsoro,
  • Nahia Cazalis-Bereicua and ,
  • Leire Aparicio-Fernandez,
  • Leire Martin-Souto,
  • Idoia Buldain,
  • Beñat Zaldibar,
  • Aitor Rementeria and
  • Andoni Ramirez-Garcia
  • + 6 authors+ 1 author

5 December 2025

Candidozyma auris (Candida auris) is an emerging pathogenic yeast of global concern due to its persistence on abiotic and biotic surfaces and the difficulty of treating the severe infections it causes, which are frequently associated with high mortal...

(This article belongs to the Special Issue Mycological Research in Spain)
  • Review
  • Open Access
28 Citations
9,418 Views
18 Pages

Pathogenesis, Prophylaxis, and Treatment of Candida auris

  • Madalina Preda,
  • Razvan Daniel Chivu,
  • Lia Mara Ditu,
  • Oana Popescu and
  • Loredana Sabina Cornelia Manolescu

Candida auris poses a serious threat to infection control and patient care since it can produce invasive infections that have a high fatality rate, has been linked to outbreaks in hospital environments, and is typically resistant to several antifunga...

(This article belongs to the Section Immunology and Immunotherapy)
  • Article
  • Open Access
18 Citations
5,839 Views
12 Pages

Candida auris in Austria—What Is New and What Is Different

  • Kathrin Spettel,
  • Richard Kriz,
  • Christine Wu,
  • Lukas Achter and ,
  • Stefan Schmid,
  • Sonia Galazka,
  • Brigitte Selitsch,
  • Iris Camp,
  • Athanasios Makristathis and
  • Birgit Willinger
  • + 6 authors+ 1 author

17 January 2023

Candida auris is a novel and emerging pathogenic yeast which represents a serious global health threat. Since its first description in Japan 2009, it has been associated with large hospital outbreaks all over the world and is often resistant to more...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Article
  • Open Access
4 Citations
2,365 Views
13 Pages

Characterization and Differentiation of Candida auris on Dixon’s Agar Using Raman Spectroscopy

  • Chrysoula Petrokilidou,
  • Eleftherios Pavlou,
  • Aristea Velegraki,
  • Anna Simou and ,
  • Ioanna Marsellou,
  • Grigorios Filis,
  • Ioannis D. Bassukas,
  • Georgios Gaitanis and
  • Nikolaos Kourkoumelis
  • + 4 authors+ 0 author

8 November 2024

Candida auris, an emerging multidrug-resistant fungal pathogen, poses significant challenges in healthcare settings due to its high misidentification rate and resilience to treatments. Despite advancements in diagnostic tools, a gap remains in rapid,...

(This article belongs to the Section Fungal Pathogens)
  • Article
  • Open Access
11 Citations
4,588 Views
20 Pages

Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

  • Stephanie Toepfer,
  • Michaela Lackner,
  • Mikhail V. Keniya,
  • Lisa-Maria Zenz and ,
  • Marianne Friemert,
  • Franz Bracher and
  • Brian C. Monk
  • + 2 authors+ 0 author

13 June 2023

Concern about the global emergence of multidrug-resistant fungal pathogens led us to explore the use of combination therapy to combat azole resistance in Candida auris. Clorgyline had previously been shown to be a multi-target inhibitor of Cdr1 and M...

(This article belongs to the Special Issue Antifungal Drug Discovery: Novel Therapies and Approaches)
  • Review
  • Open Access
61 Citations
12,088 Views
14 Pages

Candida auris: An Overview of How to Screen, Detect, Test and Control This Emerging Pathogen

  • Teresa Fasciana,
  • Andrea Cortegiani,
  • Mariachiara Ippolito,
  • Antonino Giarratano and ,
  • Orazia Di Quattro,
  • Dario Lipari,
  • Domenico Graceffa and
  • Anna Giammanco
  • + 3 authors+ 0 author

The multidrug-resistant yeast Candida auris is associated with invasive infections in critically ill patients and has been isolated in different countries worldwide. Ease of spread, prolonged persistence in the environment and antifungal drug resista...

(This article belongs to the Special Issue Diagnosis,Resistance and Treatment of Infections by Candida auris)
  • Article
  • Open Access
30 Citations
7,663 Views
10 Pages

Novel Chromogenic Medium CHROMagarTM Candida Plus for Detection of Candida auris and Other Candida Species from Surveillance and Environmental Samples: A Multicenter Study

  • Juan Vicente Mulet Bayona,
  • Carme Salvador García,
  • Nuria Tormo Palop,
  • Amparo Valentín Martín and ,
  • Carmelo González Padrón,
  • Javier Colomina Rodríguez,
  • Javier Pemán and
  • Concepción Gimeno Cardona
  • + 3 authors+ 0 author

9 March 2022

Epidemiological trends show a dramatic increase in the prevalence of fungal infections, and in the isolation of multidrug-resistant species, such as Candida auris. CHROMagarTM Candida (CC; CHROMagar, Paris, France) and other chromogenic media, which...

  • Brief Report
  • Open Access
14 Citations
6,732 Views
10 Pages

SCA Medium: A New Culture Medium for the Isolation of All Candida auris Clades

  • Ahmad Ibrahim,
  • Lucie Peyclit,
  • Rim Abdallah,
  • Saber Khelaifia and ,
  • Amanda Chamieh,
  • Jean-Marc Rolain and
  • Fadi Bittar
  • + 2 authors+ 0 author

29 May 2021

Candida auris is an emerging multidrug-resistant yeast causing nosocomial infections and associated with high mortality in immunocompromised patients. Rapid identification and characterisation are necessary for diagnosis and containing its spread. In...

(This article belongs to the Special Issue Candida auris 2.0)
  • Article
  • Open Access
27 Citations
6,800 Views
9 Pages

Essential Oils as a Good Weapon against Drug-Resistant Candida auris

  • Liliana Fernandes,
  • Rita Ribeiro,
  • Raquel Costa,
  • Mariana Henriques and
  • M. Elisa Rodrigues

Candida auris is a recently found Candida species, mainly associated with nosocomial outbreaks in intensive care hospital settings, and unlike other Candida species, it can be transmitted through person-to-person or by contact with surfaces. C. auris...

(This article belongs to the Section Antibiofilm Strategies)
  • Review
  • Open Access
31 Citations
5,472 Views
9 Pages

20 August 2019

Recently, global health professionals have been significantly challenged by the emergence of Candida auris and its propensity to colonize human skin, persist in the healthcare environment, and cause healthcare-associated outbreaks. Additionally, C. a...

(This article belongs to the Special Issue Candida auris)
  • Article
  • Open Access
46 Citations
7,388 Views
12 Pages

Metabolic Profiling of Candida auris, a Newly-Emerging Multi-Drug Resistant Candida Species, by GC-MS

  • Mohammad H. Semreen,
  • Sameh S. M. Soliman,
  • Balsam Q. Saeed,
  • Abdullah Alqarihi and ,
  • Priya Uppuluri and
  • Ashraf S. Ibrahim
  • + 1 author+ 0 author

22 January 2019

Candida auris, a newly-emerging Candida species, is a serious global health threat due to its multi-drug resistant pattern, difficulty to diagnose, and the high mortality associated with its invasive and bloodstream infections. Unlike C. albicans, an...

(This article belongs to the Section Analytical Chemistry)
  • Article
  • Open Access
6 Citations
3,179 Views
7 Pages

Initial Results of the International Efforts in Screening New Agents against Candida auris

  • Vanice Rodrigues Poester,
  • Lívia Silveira Munhoz,
  • Jéssica Louise Benelli,
  • Aryse Martins Melo and ,
  • Abdullah M. S. Al-Hatmi,
  • David J. Larwood,
  • Marife Martinez,
  • David A. Stevens and
  • Melissa Orzechowski Xavier
  • + 4 authors+ 0 author

25 July 2022

Background: Candida auris is an emergent fungal pathogen and a global concern, mostly due to its resistance to many currently available antifungal drugs. Objective: Thus, in response to this challenge, we evaluated the in vitro activity of potential...

(This article belongs to the Special Issue Biology, Immunology, Epidemiology, and Therapy of Fungal Infections: A Themed Issue Dedicated to Professor David A. Stevens)
  • Review
  • Open Access
19 Citations
10,038 Views
11 Pages

Echinocandins as Biotechnological Tools for Treating Candida auris Infections

  • Elizabete de Souza Cândido,
  • Flávia Affonseca,
  • Marlon Henrique Cardoso and
  • Octavio Luiz Franco

22 September 2020

Candida auris has been reported in the past few years as an invasive fungal pathogen of high interest. Its recent emergence in healthcare-associated infections triggered the efforts of researchers worldwide, seeking additional alternatives to the use...

(This article belongs to the Special Issue Antifungal Peptides 2020)
  • Article
  • Open Access
1 Citations
1,430 Views
19 Pages

Flavonoids as a Potential Antifungal Alternative Against Candida auris (Candidozyma auris) from Clades III and IV

  • Jonathan García-Hernández,
  • Omar Gómez-García,
  • Lourdes Villa-Tanaca and
  • Dulce Andrade-Pavón

2 March 2026

Candida auris is a critical emerging pathogen of high priority due to its ability to develop multidrug resistance to various antifungals. Given the increase in cases associated with C. auris, it is essential to evaluate new candidates with antifungal...

(This article belongs to the Special Issue Candidiasis: Changes and Challenges in Its Epidemiology, Pathogenesis, Diagnosis, Treatment and Prevention)
  • Review
  • Open Access
89 Citations
11,904 Views
16 Pages

Antifungal Resistance in Candida auris: Molecular Determinants

  • María Guadalupe Frías-De-León,
  • Rigoberto Hernández-Castro,
  • Tania Vite-Garín,
  • Roberto Arenas and ,
  • Alexandro Bonifaz,
  • Laura Castañón-Olivares,
  • Gustavo Acosta-Altamirano and
  • Erick Martínez-Herrera
  • + 3 authors+ 0 author

Since Candida auris integrates strains resistant to multiple antifungals, research has been conducted focused on knowing which molecular mechanisms are involved. This review aims to summarize the results obtained in some of these studies. A search wa...

(This article belongs to the Special Issue Diagnosis,Resistance and Treatment of Infections by Candida auris)
  • Article
  • Open Access
55 Citations
6,921 Views
11 Pages

International Multicentre Study of Candida auris Infections

  • Nirav Pandya,
  • Yasemin Cag,
  • Nenad Pandak,
  • Abdullah Umut Pekok and ,
  • Aruna Poojary,
  • Folusakin Ayoade,
  • Teresa Fasciana,
  • Anna Giammanco,
  • Hulya Caskurlu and
  • Hakan Erdem
  • + 9 authors+ 4 authors

19 October 2021

Background:Candida auris has emerged globally as a multi-drug resistant yeast and is commonly associated with nosocomial outbreaks in ICUs. Methods: We conducted a retrospective observational multicentre study to determine the epidemiology of C. auri...

(This article belongs to the Special Issue Invasive Candidiasis)
  • Review
  • Open Access
81 Citations
11,714 Views
13 Pages

Ibrexafungerp: A Novel Oral Triterpenoid Antifungal in Development for the Treatment of Candida auris Infections

  • Mahmoud Ghannoum,
  • Maiken Cavling Arendrup,
  • Vishnu P. Chaturvedi,
  • Shawn R. Lockhart and ,
  • Thomas S. McCormick,
  • Sudha Chaturvedi,
  • Elizabeth L. Berkow,
  • Deven Juneja,
  • Bansidhar Tarai and
  • Thomas J. Walsh
  • + 7 authors+ 2 authors

Candida auris is an emerging multidrug-resistant fungal pathogen reported worldwide. Infections due to C. auris are usually nosocomial and associated with high rates of fluconazole resistance and mortality. Echinocandins are utilized as the first-lin...

(This article belongs to the Special Issue Diagnosis,Resistance and Treatment of Infections by Candida auris)
  • Review
  • Open Access
96 Citations
14,253 Views
11 Pages

Candida auris: A Review of Recommendations for Detection and Control in Healthcare Settings

  • Diego H. Caceres,
  • Kaitlin Forsberg,
  • Rory M. Welsh,
  • David Joseph Sexton and ,
  • Shawn R. Lockhart,
  • Brendan R. Jackson and
  • Tom Chiller
  • + 2 authors+ 0 author

28 November 2019

Candida auris is an emerging multidrug-resistant fungal pathogen. Since first reported in 2009, C. auris has caused healthcare outbreaks around the world, often involving high mortality. Identification of C. auris has been a major challenge as many c...

(This article belongs to the Special Issue Candida auris)
  • Review
  • Open Access
35 Citations
9,858 Views
15 Pages

12 December 2020

Candida auris is a globally emerging pathogen that has been identified in urinary tract infections (UTIs) worldwide. The novel pathogen is characterized by common misidentification, difficult eradication, and multidrug resistance. To date, there is a...

(This article belongs to the Special Issue Diagnosis,Resistance and Treatment of Infections by Candida auris)
  • Review
  • Open Access
10 Citations
3,506 Views
12 Pages

Cerebrospinal Drain Infection by Candida auris: A Case Report and Review of the Literature

  • Asimenia Halioti,
  • Charikleia S. Vrettou,
  • Eleftherios Neromyliotis,
  • Evdokia Gavrielatou and ,
  • Aikaterini Sarri,
  • Zoi Psaroudaki and
  • Eleni E. Magira
  • + 2 authors+ 0 author

11 December 2024

Candida auris is notorious for its ability to spread within healthcare environments, particularly in intensive care units (ICUs), posing significant challenges for clinicians as treatment options become limited. This is especially concerning in the c...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Article
  • Open Access
14 Citations
5,744 Views
19 Pages

5 July 2023

The two fungal human pathogens, Candida auris and Candida albicans, possess a variety of virulence mechanisms. Among them are the formation of biofilms to protect yeast against harsh conditions through the development of (pseudo)hyphae whilst also fa...

(This article belongs to the Section Fungal Cell Biology, Metabolism and Physiology)
  • Case Report
  • Open Access
4 Citations
4,506 Views
9 Pages

Report of the First Case of Candida auris Identified in Jordan

  • Jamal Wadi Al-Ramahi,
  • Rola Ali Ghanem,
  • Omar Helmy Sayyouh,
  • Dima Al-Jammal and ,
  • Mayar M. Said,
  • Salwa Nasrat,
  • Mona El-Shokry,
  • Mahmoud Gazo and
  • Tamer Saied Osman
  • + 4 authors+ 0 author

3 October 2023

Candida auris (C. auris) is an opportunistic budding yeast that has been identified across 41 countries, including several countries in the Middle East. The increasing global concern stems from the pathogen’s acquired resistance to antifun...

  • Article
  • Open Access
10 Citations
4,096 Views
14 Pages

Cell Surface Expression of Nrg1 Protein in Candida auris

  • Anuja Paudyal and
  • Govindsamy Vediyappan

31 March 2021

Candida auris is an emerging antifungal resistant human fungal pathogen increasingly reported in healthcare facilities. It persists in hospital environments, and on skin surfaces, and can form biofilms readily. Here, we investigated the cell surface...

(This article belongs to the Special Issue Candida auris 2.0)
  • Article
  • Open Access
52 Citations
5,018 Views
10 Pages

Characteristics and Management of Candidaemia Episodes in an Established Candida auris Outbreak

  • Juan V. Mulet Bayona,
  • Nuria Tormo Palop,
  • Carme Salvador García,
  • Paz Herrero Rodríguez and ,
  • Vicente Abril López de Medrano,
  • Carolina Ferrer Gómez and
  • Concepción Gimeno Cardona
  • + 2 authors+ 0 author

The multi-resistant yeast Candida auris has become a global public health threat because of its ease to persist and spread in clinical environments, especially in intensive care units. One of the most severe manifestations of invasive candidiasis is...

(This article belongs to the Special Issue Diagnosis,Resistance and Treatment of Infections by Candida auris)
  • Review
  • Open Access
46 Citations
8,660 Views
40 Pages

Invasive fungal infections represent an expanding threat to public health. During the past decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida species has fundamentally increased with the advent of Candida auris. C. ...

(This article belongs to the Special Issue Human Pathogenic Fungi: Host-Pathogen Interactions and Virulence)
  • Review
  • Open Access
66 Citations
13,189 Views
16 Pages

Candida auris: A Quick Review on Identification, Current Treatments, and Challenges

  • Lucia Černáková,
  • Maryam Roudbary,
  • Susana Brás,
  • Silva Tafaj and
  • Célia F. Rodrigues

Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misle...

(This article belongs to the Special Issue Tackling New and Reemerging Infectious Diseases through the Development of Novel Anti-infectives)
  • Review
  • Open Access
47 Citations
7,621 Views
18 Pages

Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia

  • Nishanthinie Thatchanamoorthy,
  • Velayuthan Rukumani Devi,
  • Samudi Chandramathi and
  • Sun Tee Tay

26 October 2022

Candida auris, a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has bee...

(This article belongs to the Topic Fungal Diversity)
  • Article
  • Open Access
27 Citations
8,007 Views
31 Pages

Melanization of Candida auris Is Associated with Alteration of Extracellular pH

  • Daniel F. Q. Smith,
  • Nathan J. Mudrak,
  • Daniel Zamith-Miranda,
  • Leandro Honorato and ,
  • Leonardo Nimrichter,
  • Christine Chrissian,
  • Barbara Smith,
  • Gary Gerfen,
  • Ruth E. Stark and
  • Arturo Casadevall
  • + 6 authors+ 1 author

11 October 2022

Candida auris is a recently emerged global fungal pathogen, which causes life-threatening infections, often in healthcare settings. C. auris infections are worrisome because the fungus is often resistant to multiple antifungal drug classes. Furthermo...

(This article belongs to the Special Issue Fifty Years of Fungi: A Special Issue Honoring the Contributions of Dr. June Kwon-Chung to the Field of Medical Mycology)
  • Communication
  • Open Access
29 Citations
6,495 Views
14 Pages

Diagnostic Allele-Specific PCR for the Identification of Candida auris Clades

  • Hans Carolus,
  • Stef Jacobs,
  • Celia Lobo Romero,
  • Quinten Deparis and ,
  • Christina A. Cuomo,
  • Jacques F. Meis and
  • Patrick Van Dijck
  • + 2 authors+ 0 author

13 September 2021

Candida auris is an opportunistic pathogenic yeast that emerged worldwide during the past decade. This fungal pathogen poses a significant public health threat due to common multidrug resistance (MDR), alarming hospital outbreaks, and frequent miside...

(This article belongs to the Special Issue Candida auris 2.0)
  • Article
  • Open Access
3 Citations
3,804 Views
16 Pages

The Potential of Dutasteride for Treating Multidrug-Resistant Candida auris Infection

  • J. Francis Borgio,
  • Noor B. Almandil,
  • Prathas Selvaraj,
  • J. Sherlin John and ,
  • Rahaf Alquwaie,
  • Eman AlHasani,
  • Norah F. Alhur,
  • Razan Aldahhan,
  • Reem AlJindan and
  • Sayed AbdulAzeez
  • + 8 authors+ 3 authors

Novel antifungal drugs are urgently needed to treat candidiasis caused by the emerging fungal multidrug-resistant pathogen Candida auris. In this study, the most cost-effective drug repurposing technology was adopted to identify an appropriate option...

(This article belongs to the Special Issue Novel Drugs, Targets and Therapies Against Infectious Diseases)
  • Article
  • Open Access
14 Citations
4,280 Views
11 Pages

Description of Candida auris Occurrence in a Tertiary Health Institution in Riyadh, Saudi Arabia

  • Fatimah S. Alshahrani,
  • Abba Amsami Elgujja,
  • Sara Alsubaie,
  • Salah Ahmed Ezreqat and ,
  • Ahmed M. Albarraq,
  • Mazin Barry,
  • Khalifa Binkhamis and
  • Lulwa Alabdan
  • + 3 authors+ 0 author

12 December 2023

Background: Candida auris is an emerging multidrug-resistant fungal pathogen that represents a current serious threat to healthcare settings. Objective: The objective was to determine the prevalence of C. auris in a Riyadh hospital since its initial...

  • Systematic Review
  • Open Access
33 Citations
9,851 Views
22 Pages

Potential Environmental Reservoirs of Candida auris: A Systematic Review

  • Isabel Silva,
  • Isabel M. Miranda and
  • Sofia Costa-de-Oliveira

8 May 2024

Candida auris, a multidrug-resistant yeast, poses significant challenges in healthcare settings worldwide. Understanding its environmental reservoirs is crucial for effective control strategies. This systematic review aimed to review the literat...

(This article belongs to the Collection Invasive Candidiasis)
  • Systematic Review
  • Open Access
39 Citations
6,383 Views
19 Pages

Candida auris Infection, a Rapidly Emerging Threat in the Neonatal Intensive Care Units: A Systematic Review

  • Rozeta Sokou,
  • Alexia Eleftheria Palioura,
  • Paschalia Kopanou Taliaka,
  • Aikaterini Konstantinidi and ,
  • Andreas G. Tsantes,
  • Daniele Piovani,
  • Konstantina A. Tsante,
  • Eleni A. Gounari,
  • Zoi Iliodromiti and
  • Nicoletta Iacovidou
  • + 8 authors+ 3 authors

10 March 2024

(1) Background: In recent years, a global epidemiological shift in candidemia has been observed, marked by the emergence of resistant non-albicans Candida species. Candida auris, in particular, has become a significant global concern, causing infecti...

(This article belongs to the Section Clinical Pediatrics)
  • Review
  • Open Access
16 Citations
8,920 Views
23 Pages

Current Perspectives of Antifungal Therapy: A Special Focus on Candida auris

  • Arumugam Ganeshkumar,
  • Manickam Muthuselvam,
  • Patricia Michelle Nagai de Lima,
  • Rajendren Rajaram and
  • Juliana Campos Junqueira

6 June 2024

Candida auris is an emerging Candida sp. that has rapidly spread all over the world. The evidence regarding its origin and emerging resistance is still unclear. The severe infection caused by this species results in significant mortality and morbidit...

(This article belongs to the Special Issue Alternative Therapeutic Approaches of Candida Infections, 3rd Edition)

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