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Mycological Research in Spain
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Mycological Research in Spain

A special issue of Journal of Fungi (ISSN 2309-608X).

Deadline for manuscript submissions: 31 October 2025 | Viewed by 1262

Special Issue Editor

Dr. Ana Alastruey-Izquierdo

E-Mail Website
Guest Editor
National Centre for Microbiology, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
Interests: antifungal susceptibility testing; antifungal resistance; medical mycology; taxonomy; diagnosis of fungal infections; epidemiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of the Journal of Fungi is dedicated to showcasing fungal research conducted in Spain or by Spanish researchers. This Special Issue aims to spotlight the rich contributions of Spanish researchers to the global understanding of fungi and their multifaceted roles in ecosystems, health, and industry.

We invite submissions across a broad spectrum of mycological topics, including, but not limited to, the following:

  1. Fungal pathogenesis and disease control;
  2. Surveillance and antifungal susceptibility testing;
  3. Diagnostic and management of fungal infections;
  4. Fungal outbreaks;
  5. Pathogenic fungi and their impacts on human and animal health;
  6. Fungal biodiversity and systematics in Spanish ecosystems;
  7. Fungal ecology and its interactions with the environment;
  8. Molecular and genetic studies of fungi;
  9. The use of fungi in biotechnology and industrial applications.

This Special Issue offers a platform to highlight the exceptional work carried out by Spanish researchers and to showcase the unique fungal diversity found in Spain. We believe that this collection will not only contribute significantly to the field of mycology but also foster new collaborations and spark future research initiatives.

Dr. Ana Alastruey-Izquierdo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fungal pathogenesis fungal disease control
  • antifungal susceptibility testing
  • fungal biodiversity and systematics
  • fungal ecology molecular and genetic studies of fungi
  • fungal biotechnology and industrial applications

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  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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12 pages, 534 KiB  
Article
Clinical Significance and Therapeutic Challenges of Scedosporium spp. and Lomentospora prolificans Isolates in a Single-Center Cohort of Lung Transplant Recipients
by Sarela García-Masedo Fernández, Rosalía Laporta, Myriam Aguilar, Christian García Fadul, María Cabrera Pineda, Ana Alastruey-Izquierdo, Ana Royuela, Isabel Sánchez Romero and Piedad Ussetti Gil
J. Fungi 2025, 11(4), 291; https://doi.org/10.3390/jof11040291 - 8 Apr 2025
Viewed by 231
Abstract
(1) Background: Emerging fungal infections associated with Scedosporium spp. and Lomentospora prolificans (S/L) are becoming more frequent and are very difficult to treat. Our objective was to analyze the frequency and management of S/L isolates in lung transplant (LTx) recipients, the patient outcomes and [...] Read more.
(1) Background: Emerging fungal infections associated with Scedosporium spp. and Lomentospora prolificans (S/L) are becoming more frequent and are very difficult to treat. Our objective was to analyze the frequency and management of S/L isolates in lung transplant (LTx) recipients, the patient outcomes and in vitro antifungal sensitivity. (2) Methods: We included all patients with S/L isolation during post-transplant follow-up. Data were collected from electronic medical records. All samples were cultivated on Sabouraud Chloramphenicol agar. Isolations of S/L were submitted to in vitro susceptibility tests. (3) Results: A total of 11 (2%) of the 576 LTx recipients included had at least one isolation of S/L. Classification for the 11 cases were colonization (4; 36%) and infection (7; 65%). Five infections were pulmonary (71%) and two were disseminated (29%). S. apiospermum complex was the most frequently occurring isolation in patients with pulmonary disease while L. prolificans was the most frequent in patients with disseminated disease. Ten patients were treated. The most frequent antifungal drugs used were voriconazole (n = 8) and terbinafine (n = 6). Seven patients (70%) received more than one drug. The mortality rate associated with L. prolificans isolation was 50% for colonization and 100% for disseminated disease. (4) Conclusions: Scedosporium spp. and L. prolificans infections are associated with high morbidity and mortality rates. New diagnostic and therapeutic tools are required to reduce the impact of these infections. Full article
(This article belongs to the Special Issue Mycological Research in Spain)
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Review

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21 pages, 1421 KiB  
Review
Mycobiota and Antifungal Antibodies as Emerging Targets for the Diagnosis and Prognosis of Human Diseases
by Eguzkiñe Diez-Martin, Leidi Hernandez-Suarez, Egoitz Astigarraga, Andoni Ramirez-Garcia and Gabriel Barreda-Gómez
J. Fungi 2025, 11(4), 296; https://doi.org/10.3390/jof11040296 - 9 Apr 2025
Viewed by 436
Abstract
The human body is colonized by diverse microorganisms, with bacteria being the most extensively studied. However, fungi, collectively known as “the mycobiota,” are increasingly recognized as integral components of the microbiota, inhabiting nearly all mucosal surfaces. Commensal fungi influence host immunity similarly to [...] Read more.
The human body is colonized by diverse microorganisms, with bacteria being the most extensively studied. However, fungi, collectively known as “the mycobiota,” are increasingly recognized as integral components of the microbiota, inhabiting nearly all mucosal surfaces. Commensal fungi influence host immunity similarly to bacteria and contribute to other essential functions, including metabolism. This emerging understanding positions fungi as potential biomarkers for the diagnosis and prognosis of various diseases. In this review, we explore the dual roles of fungi as both commensals and pathogens, and the potential of antifungal antibodies to serve as diagnostic and prognostic tools, especially in chronic immune-inflammatory non-communicable diseases, including inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, and neurodegenerative disorders. Finally, we address current challenges and outline future perspectives for leveraging fungal biomarkers in clinical practice. Full article
(This article belongs to the Special Issue Mycological Research in Spain)
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