247 Results Found

At present, the details of lamina alterations after baculovirus infection remain elusive. In this study, a lamin gene in the Sf9 cell line of Spodoptera frugiperda was cloned. The open reading frame (orf) of the Sf9 lamin was 1860 bp and encoded a pr...

The Muji spring travertines, located in the Muji Basin in the eastern Pamirs Plateau, represent a typical spring deposit found on plateaus that is characterized by arid and semi-arid climatic conditions. However, its formation mechanisms remain poorl...

The mechanical properties and structure alteration (e.g., layer morphology and thickness) of the oesophagus wall can reflect its pathological conditions. Hence, quantitative measurement of the above-mentioned properties can play a significant role in...

Mechanotransduction translates forces into biological responses and regulates cell functionalities. It is implicated in several diseases, including laminopathies which are pathologies associated with mutations in lamins and lamin-associated proteins....

This paper presents a comprehensive study of the influence of various composite structure characteristics, such as stacking sequences and fiber orientations, on the dynamic behavior of glass fiber reinforced composite (GFRC) plates for modeling isola...

An analytical approach with the help of numerical simulations based on the equivalent constraint model (ECM) was proposed to investigate the progressive failure behavior of symmetric fiber-reinforced composite laminates damaged by transverse ply crac...

In order to study the nonlinear behaviors and interactions among the constituents for the composite material structure under the tensile load, multiscale damage model using generalized method of cells (GMC) and a lamina-level progressive damage model...

Extracellular mechanical stimuli are translated into biochemical signals inside the cell via mechanotransduction. The nucleus plays a critical role in mechanoregulation, which encompasses mechanosensing and mechanotransduction. The nuclear lamina und...

Hutchinson–Gilford Progeria Syndrome (HGPS) is an extremely rare genetic disorder that causes accelerated aging, due to a pathogenic variant in the LMNA gene. This pathogenic results in the production of progerin, a defective protein that disru...

Barrier-to-autointegration factor (BAF) is an essential component of the nuclear lamina. Encoded by BANF1, this DNA binding protein contributes to the regulation of gene expression, cell cycle progression, and nuclear integrity. A rare recessive BAF...

A- and B-type lamins are type V intermediate filament proteins. Mutations in the genes encoding these lamins cause rare diseases, collectively called laminopathies. A fraction of the cells obtained from laminopathy patients show aberrations in the lo...

It is well known that the effect of shale hydration causes wellbore instability due to water phase invasion of drilling fluid to lamellar shale rich formations. This is because of that the mechanical properties (compressive strength, elastic modulus,...

Quadriaxial non-crimp fabric (QNCF) composites are increasingly being used as primary structural materials in aircraft and automotive applications. Predicting the mechanical properties of QNCF lamina is more complicated compared with that of unidirec...

Hydraulic fracturing in shale reservoirs is affected by microscale structural and material heterogeneity. However, studies on fracture responses to the injection rate across different microstructural types remain limited. To examine the coupled effec...

Testicular stiffness is a potential indicator of spermatogenic activity. Herein, we investigated the relationship between testicular stiffness and intratesticular morphology in Syrian hamsters by using a robotic system with a micro-force sensor. Anim...

The electrical conductivity of glass fiber-reinforced plastic (GFRP) with epoxy matrix modified by multiwall carbon nanotubes (MWCNT) was studied. The electrical conductivity of nanomodified lamina and multi-layered GFRP was investigated on several l...

Humans and rodents exhibit a divergent obesity phenotype where not all individuals exposed to a high calorie diet become obese. We hypothesized that in C57BL/6NTac mice, despite a shared genetic background and diet, variations in individual gut micro...

The identification of sedimentary structures in lithofacies is of great significance to the exploration and development of Paleogene shale in the Boxing Sag. However, due to the scale mismatch between the thickness of laminae and the vertical resolut...

Equine Caudal Cervical Morphologic Variation (ECCMV) is a congenital malformation of the caudal cervical spine distinct from the more commonly recognized Cervical Vertebral Stenotic Myelopathy (CVSM). The most common presentation of ECCMV is recogniz...

Plants are exposed to various external stresses influencing physiology, anatomy, and morphology. Shape, geometry, and size of shoots and leaves are particularly affected. Among the latter, peltate leaves are not very common and so far, only few studi...

Heterotis niloticus is a basal teleost, belonging to the Osteoglossidae family, which is widespread in many parts of Africa. The digestive tract of H. niloticus presents similar characteristics to those of higher vertebrates, exhibiting a gizzard-lik...

The additive manufacturing represents a new production method of composites reinforced with a continuous fibre. In recent times, the material produced by this new manufacturing method constituted a replacement for conventional materials—e.g., s...

The arboviral disease cycle requires that key tissues in the arthropod vector become persistently infected with the virus. The midgut is the first organ in the mosquito that needs to be productively infected with an orally acquired virus. Following m...

In this study, we propose a new intelligent system to automatically quantify the morphological parameters of the lamina cribrosa (LC) of the optical coherence tomography (OCT), including depth, curve depth, and curve index from OCT images. The propos...

A novel passive vibration-damping device is proposed and investigated for a large deployable solar array. One strategy for achieving high damping in a solar panel is using a yoke structure comprising a hyperelastic shape memory alloy and multiple vis...

The extensive development of lamination structures in shale significantly influences its mechanical properties. However, a systematic analysis of how laminae affect the macroscopic mechanical behavior of rocks remains absent. In this study, field emi...

Eukaryotic genomes are packaged into high-order chromatin structures organized in discrete territories inside the cell nucleus, which is surrounded by the nuclear envelope acting as a barrier. This chromatin organization is complex and dynamic and, t...

Laminate plate and shell structures with symmetric cross-ply configurations are widely used due to their high stiffness-to-weight ratio. However, conventional lamination theories rely on simplifying assumptions that may introduce inaccuracies. This s...

The linker of nucleoskeleton and cytoskeleton (LINC) complex is composed of the outer and inner nuclear membrane protein families Klarsicht, Anc-1, and Syne homology (KASH), and Sad1 and UNC-84 (SUN) homology domain proteins. Increasing evidence has...

Background: Instrument-assisted manual therapy (IAMT) is indicated to improve flexibility, reduce pain, and induce hyperaemia locally and along myofascial chains. The underlying effects are largely unclear. This randomised, placebo-controlled pilot s...

Fine-grained sedimentary rocks exhibit significant textural heterogeneity, often obscured by conventional grain size analysis techniques that require sample disaggregation. We propose a non-destructive, image-based grain size characterization workflo...

Background and Objectives: There are only a few studies regarding gut subepithelial telocytes (TCs). The telopodes, namely peculiar TCs’ prolongations described on two-dimensional cuts, are not enough to differentiate this specific cell type. S...

The choroid plexus (CP) is a structure in the brain ventricles that produces the main part of the cerebrospinal fluid (CSF). It is covered with specialized cells which show epithelial characteristics and are the site of the blood–CSF barrier. T...

A high strength recycled newspaper (NP)/high density polyethylene (HDPE) laminated composite was developed using NP laminas as reinforcement and HDPE film as matrix. Herein, NP fiber was modified with stearic acid (SA) to enhance the water resistance...

OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, has specific connective tissue types for skin, bones, reticulate, basal lamina, bones, cell surfaces, while type II co...

During embryonic development, stem cells undergo the differentiation process so that they can specialize for different functions within the organism. Complex programs of gene transcription are crucial for this process to happen. Epigenetic modificati...

In eukaryotic cells, the nucleus houses the genomic material of the cell. The physical properties of the nucleus and its ability to sense external mechanical cues are tightly linked to the regulation of cellular events, such as gene expression. Nucle...

The nucleus serves as a pivotal regulatory and control hub in the cell, governing numerous aspects of cellular functions, including DNA replication, transcription, and RNA processing. Therefore, any deviations in nuclear morphology, structure, or org...

Natural fractures within the lacustrine mixed shale oil reservoirs of the upper member of the Lower Ganchaigou Formation (E32) in the Ganchaigou area of the Qaidam Basin are pivotal to the exploration and development of shale oil and gas. This resear...

Composite materials are widely used for their peculiar combination of excellent structural, mechanical, and damping properties. This work presents an experimental study on the dissipation properties of disk-shaped composite specimens exploiting vibra...

Secretory IgA (SIgA) is the dominant antibody class in mucosal secretions. The majority of plasma cells producing IgA are located within mucosal membranes lining the intestines. SIgA protects against the adhesion of pathogens and their penetration in...

Brassinosteroids (BRs) are an important group of polyhydroxylated naturally occurring steroidal phytohormones found in the plant kingdom in extremely low amounts. Due to the low concentrations in which these compounds are found, much effort has been...

The structural integrity of the gastrointestinal tract is important because it dictates the functionality of this system. Regarding this, gut-associated lymphoid tissue (GALT) has a significant role in immunity. Most cancer research focuses on organi...

Introduction: Etiopathogenesis and the symptomatology of ureteropelvic junction obstruction (UPJO) in the pediatric population has not yet been definitely clarified, suggesting a multifactorial nature of the condition. The aim was to analyze the asso...

Background and Clinical Significance: Among the odontogenic tumors, ameloblastoma is one of the most notorious, although it remains relatively rare, accounting for approximately one percent of all oral tumors. This neoplasm, derived from odontogenic...

The cell nucleus contains a number of membrane-less organelles or intra-nuclear compartments. These compartments are dynamic structures representing liquid-droplet phases which are only slightly denser than the bulk intra-nuclear fluid. They possess...

The nuclear envelope (NE) of eukaryotic cells has a highly structural architecture, comprising double lipid-bilayer membranes, nuclear pore complexes, and an underlying nuclear lamina network. The NE structure is held in place through the membrane-bo...

The nucleolus is the largest substructure in the nucleus, where ribosome biogenesis takes place, and forms around the nucleolar organizer regions (NORs) that comprise ribosomal RNA (rRNA) genes. Each cell contains hundreds of rRNA genes, which are or...

Oxidative stress is a physiological condition that arises when there is an imbalance between the production of reactive oxygen species (ROS) and the ability of cells to neutralize them. ROS can damage cellular macromolecules, including lipids, protei...

This paper describes the transition towards a composite structure, with the same overall aerodynamic characteristics, for a tail rotor blade of an IAR330 helicopter. The newly proposed structure of the composite blade is made of a carbon-roving spar...