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Nutrients, Volume 14, Issue 2

2022 January-2 - 168 articles

Cover Story: Several studies relate Mediterranean diet and virgin olive oils (VOO) intake with lower risk of several chronic diseases, including breast cancer. Many of them described antitumor properties of isolated minor compounds present in VOO, but beneficial properties of VOO arise from the effects of all its compounds acting together. The aim of the present study was to test the antitumor effects of two minor compounds from VOO (hydroxytyrosol (HT) and squalene (SQ)) on highly metastatic human breast tumor cells when acting in combination. Both molecules separately have no antitumour activity but when they act in combination, they inhibit cell proliferation, and promote apoptosis and DNA damage in metastatic breast cancer cells. Therefore, our results suggest that the health-promoting properties of VOO may be due, at least in part, to the combined action of these two minor compounds. View this paper
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Articles (168)

  • Review
  • Open Access
91 Citations
84,040 Views
31 Pages

17 January 2022

The objective of the present research was to review the state of the art on the consequences of drinking coffee at the different levels of the gastrointestinal tract. At some steps of the digestive process, the effects of coffee consumption seem rath...

  • Article
  • Open Access
18 Citations
5,746 Views
11 Pages

Adansonia digitata L. (Baobab Fruit) Effect on Postprandial Glycemia in Healthy Adults: A Randomized Controlled Trial

  • Keyla Rita,
  • Maria Alexandra Bernardo,
  • Maria Leonor Silva,
  • José Brito,
  • Maria Fernanda Mesquita,
  • Ana Maria Pintão and
  • Margarida Moncada

17 January 2022

Baobab fruits have been traditionally used in Africa due to their therapeutic properties attributed to their high polyphenol content. The aim of the study was to investigate the effect of baobab fruit on postprandial glycaemia in healthy adults and t...

  • Article
  • Open Access
30 Citations
9,778 Views
18 Pages

Predictors of Symptom-Specific Treatment Response to Dietary Interventions in Irritable Bowel Syndrome

  • Esther Colomier,
  • Lukas Van Oudenhove,
  • Jan Tack,
  • Lena Böhn,
  • Sean Bennet,
  • Sanna Nybacka,
  • Stine Störsrud,
  • Lena Öhman,
  • Hans Törnblom and
  • Magnus Simrén

17 January 2022

(1) Background: Predictors of dietary treatment response in irritable bowel syndrome (IBS) remain understudied. We aimed to investigate predictors of symptom improvement during the low FODMAP and the traditional IBS diet for four weeks. (2) Methods:...

  • Article
  • Open Access
14 Citations
5,726 Views
14 Pages

Marine Oil from C. finmarchicus Enhances Glucose Homeostasis and Liver Insulin Resistance in Obese Prediabetic Individuals

  • Milena Burhop,
  • Jan Philipp Schuchardt,
  • Josefine Nebl,
  • Mattea Müller,
  • Ralf Lichtinghagen and
  • Andreas Hahn

17 January 2022

The intermediate state between normal glucose tolerance and overt type 2 diabetes mellitus is associated with micro- and macrovascular diseases, requiring safe and cost-effective treatment measures interventions. A novel source of LC n-3 FAs is Calan...

  • Article
  • Open Access
4 Citations
4,364 Views
11 Pages

Genome-Wide Analysis of Disordered Eating Behavior in the Mexican Population

  • José Jaime Martínez-Magaña,
  • Sandra Hernandez,
  • Ana Rosa Garcia,
  • Valeria Cardoso-Barajas,
  • Emmanuel Sarmiento,
  • Beatriz Camarena,
  • Alejandro Caballero,
  • Laura Gonzalez,
  • Jorge Ameth Villatoro-Velazquez and
  • Alma Delia Genis-Mendoza
  • + 6 authors

17 January 2022

Alterations in eating behavior characterized eating disorders (ED). The genetic factors shared between ED diagnoses have been underexplored. The present study performed a genome-wide association study in individuals with disordered eating behaviors i...

  • Article
  • Open Access
7 Citations
3,457 Views
19 Pages

Plinia trunciflora Extract Administration Prevents HI-Induced Oxidative Stress, Inflammatory Response, Behavioral Impairments, and Tissue Damage in Rats

  • Andrey Vinicios S. Carvalho,
  • Rafael T. Ribeiro,
  • Luz Elena Durán-Carabali,
  • Ana Paula R. Martini,
  • Eduarda Hoeper,
  • Eduardo F. Sanches,
  • Eduardo Luis Konrath,
  • Carla Dalmaz,
  • Moacir Wajner and
  • Carlos Alexandre Netto

17 January 2022

The disruption of redox homeostasis and neuroinflammation are key mechanisms in the pathogenesis of brain hypoxia–ischemia (HI); medicinal plants have been studied as a therapeutic strategy, generally associated with the prevention of oxidative...

  • Review
  • Open Access
14 Citations
5,281 Views
10 Pages

17 January 2022

The population suffering from obesity is rapidly increasing all over the world. Bariatric surgery has shown to be the treatment of choice in patients with severe obesity. A Mediterranean diet has long been acknowledged to be one of the healthiest die...

  • Systematic Review
  • Open Access
2 Citations
4,245 Views
25 Pages

Sex-Specific Effects of Nutritional Supplements for Infants Born Early or Small: An Individual Participant Data Meta-Analysis (ESSENCE IPD-MA) II: Growth

  • Luling Lin,
  • Greg D. Gamble,
  • Caroline A. Crowther,
  • Frank H. Bloomfield,
  • Massimo Agosti,
  • Stephanie A. Atkinson,
  • Augusto Biasini,
  • Nicholas D. Embleton,
  • Fernando Lamy Filho and
  • Jane E. Harding
  • + 16 authors

17 January 2022

Neonatal nutritional supplements may improve early growth for infants born small, but effects on long-term growth are unclear and may differ by sex. We assessed the effects of early macronutrient supplements on later growth. We searched databases and...

  • Article
  • Open Access
25 Citations
4,467 Views
13 Pages

Antibacterial Activity and Epigenetic Remodeling of Essential Oils from Calabrian Aromatic Plants

  • Patrizia D’Aquila,
  • Ersilia Paparazzo,
  • Michele Crudo,
  • Sonia Bonacci,
  • Antonio Procopio,
  • Giuseppe Passarino and
  • Dina Bellizzi

17 January 2022

Natural compounds have historically had a wide application in nutrition. Recently, a fundamental role has been identified for essential oils extracted from aromatic plants for their nutritional, antimicrobial, and antioxidant properties, and as food...

  • Article
  • Open Access
17 Citations
5,052 Views
10 Pages

17 January 2022

Micro-inflammation in the gut, assessed by fecal calprotectin (FC), is considered a component of the pathogenesis of functional diarrhea (FD). Since probiotics may suppress micro-inflammation in the intestine by competing with harmful bacteria, we hy...

  • Article
  • Open Access
18 Citations
4,733 Views
17 Pages

A. muciniphila Supplementation in Mice during Pregnancy and Lactation Affects the Maternal Intestinal Microenvironment

  • Yuli Qi,
  • Leilei Yu,
  • Fengwei Tian,
  • Jianxin Zhao,
  • Hao Zhang,
  • Wei Chen and
  • Qixiao Zhai

17 January 2022

During pregnancy and lactation, considerable factors that affect the maternal microbiome are associated with the advancement of numerous diseases, which can potentially affect offspring health. Probiotics have shown potential for the maintenance of m...

  • Article
  • Open Access
13 Citations
3,846 Views
17 Pages

Effect of Type 2 Diabetes and Impaired Glucose Tolerance on Digestive Enzymes and Glucose Absorption in the Small Intestine of Young Rats

  • Lyudmila V. Gromova,
  • Alexandr S. Polozov,
  • Elizaveta V. Savochkina,
  • Anna S. Alekseeva,
  • Yulia V. Dmitrieva,
  • Oleg V. Kornyushin and
  • Andrey A. Gruzdkov

17 January 2022

The reactions of intestinal functional parameters to type 2 diabetes at a young age remain unclear. The study aimed to assess changes in the activity of intestinal enzymes, glucose absorption, transporter content (SGLT1, GLUT2) and intestinal structu...

  • Feature Paper
  • Article
  • Open Access
2 Citations
4,125 Views
15 Pages

17 January 2022

This study compared the effects of a real-world multidisciplinary intervention with additional exercise or nutritional elements and investigated the effectiveness of a booster intervention after weight regain. A total of 242 children and adolescents...

  • Article
  • Open Access
8 Citations
4,189 Views
9 Pages

Food Protein-Induced Enterocolitis Syndrome in Children with Down Syndrome: A Pilot Case-Control Study

  • Fumiko Okazaki,
  • Hiroyuki Wakiguchi,
  • Yuno Korenaga,
  • Kazumasa Takahashi,
  • Hiroki Yasudo,
  • Ken Fukuda,
  • Mototsugu Shimokawa and
  • Shunji Hasegawa

17 January 2022

Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobin E-mediated food hypersensitivity disorder. However, little is known about the clinical features of FPIES in patients with Down syndrome (DS). Medical records of children with D...

  • Article
  • Open Access
7 Citations
7,479 Views
13 Pages

A Specific High-Protein Weight Loss Program Does Not Impair Renal Function in Patients Who Are Overweight/Obese

  • Anne-Sophie Truche,
  • Sébastien Bailly,
  • Odile Fabre,
  • Rémy Legrand and
  • Philippe Zaoui

17 January 2022

Although high-protein diets appear to be the most efficient way to lose weight, concerns may arise about their innocuity on renal function. The objective of this study is to assess the impact of a weight loss program on renal function. A multicentric...

  • Article
  • Open Access
12 Citations
4,282 Views
11 Pages

Switching to Regular Diet Partially Resolves Liver Fibrosis Induced by High-Fat, High-Cholesterol Diet in Mice

  • Muhammad Farooq,
  • Huma Hameed,
  • Marie-Thérèse Dimanche-Boitrel,
  • Claire Piquet-Pellorce,
  • Michel Samson and
  • Jacques Le Seyec

17 January 2022

The globally prevalent disease, non-alcoholic steatohepatitis (NASH), is characterized by a steatotic and inflammatory liver. In NASH patients, tissue repair mechanisms, activated by the presence of chronic liver damage, lead to the progressive onset...

  • Article
  • Open Access
36 Citations
5,586 Views
13 Pages

Clinical Impact of Nutritional Status and Sarcopenia in Pediatric Patients with Bone and Soft Tissue Sarcomas: A Pilot Retrospective Study (SarcoPed)

  • Alberto Romano,
  • Silvia Triarico,
  • Emanuele Rinninella,
  • Luigi Natale,
  • Maria Gabriella Brizi,
  • Marco Cintoni,
  • Pauline Raoul,
  • Palma Maurizi,
  • Giorgio Attinà and
  • Antonio Ruggiero
  • + 3 authors

17 January 2022

Background: We evaluated nutritional and sarcopenia status and their clinical impact in pediatric patients affected by bone and soft tissue sarcomas. Methods: Body mass index (BMI), prognostic nutritional index (PNI), and total psoas muscle area (tPM...

  • Article
  • Open Access
9 Citations
4,477 Views
13 Pages

Interaction between Dietary Fat Intake and Metabolic Genetic Risk Score on 25-Hydroxyvitamin D Concentrations in a Turkish Adult Population

  • Kubra Isgin-Atici,
  • Buthaina E. Alathari,
  • Busra Turan-Demirci,
  • Suleyman Nahit Sendur,
  • Incilay Lay,
  • Basma Ellahi,
  • Mehmet Alikasifoglu,
  • Tomris Erbas,
  • Zehra Buyuktuncer and
  • Karani Santhanakrishnan Vimaleswaran

17 January 2022

Previous studies have pointed out a link between vitamin D status and metabolic traits, however, consistent evidence has not been provided yet. This cross-sectional study has used a nutrigenetic approach to investigate the interaction between metabol...

  • Article
  • Open Access
3 Citations
3,167 Views
12 Pages

Modeling the Predictive Value of Evidence-Based Referral Criteria to Support Healthy Gestational Weight Gain among an Australian Pregnancy Cohort

  • Shanna Fealy,
  • Jenna Hollis,
  • Julia Martin,
  • Lucy Leigh,
  • Christopher Oldmeadow,
  • Clare E. Collins,
  • Roger Smith,
  • Shelley Wilkinson and
  • Alexis Hure

17 January 2022

Globally, there has been a renewed focus on addressing gestational weight gain (GWG). In Australia, the Department of Health pregnancy care guidelines recommend women be offered routine weighing and receive brief nutritional and physical activity sup...

  • Feature Paper
  • Review
  • Open Access
47 Citations
17,315 Views
21 Pages

Are We What We Eat? Impact of Diet on the Gut–Brain Axis in Parkinson’s Disease

  • Margherita Alfonsetti,
  • Vanessa Castelli and
  • Michele d’Angelo

17 January 2022

Parkinson’s disease is characterized by motor and non-motor symptoms, such as defects in the gut function, which may occur before the motor symptoms. To date, there are therapies that can improve these symptoms, but there is no cure to avoid th...

  • Article
  • Open Access
8 Citations
4,512 Views
16 Pages

Dietary Intakes of Traditional Foods for Dene/Métis in the Dehcho and Sahtú Regions of the Northwest Territories

  • Maria Ramirez Prieto,
  • Mylène Ratelle,
  • Brian Douglas Laird and
  • Kelly Skinner

16 January 2022

A dietary transition away from traditional foods and toward a diet of the predominantly unhealthy market is a public health and sociocultural concern throughout Indigenous communities in Canada, including those in the sub-Arctic and remote regions of...

  • Article
  • Open Access
40 Citations
5,058 Views
20 Pages

A Potential Synbiotic Strategy for the Prevention of Type 2 Diabetes: Lactobacillus paracasei JY062 and Exopolysaccharide Isolated from Lactobacillus plantarum JY039

  • Jiayuan Zhao,
  • Lihan Wang,
  • Shasha Cheng,
  • Yu Zhang,
  • Mo Yang,
  • Ruxue Fang,
  • Hongxuan Li,
  • Chaoxin Man and
  • Yujun Jiang

16 January 2022

The disturbance of intestinal microorganisms and the exacerbation of type 2 diabetes (T2D) are mutually influenced. In this study, the effect of exopolysaccharides (EPS) from Lactobacillus plantarum JY039 on the adhesion of Lactobacillus paracasei JY...

  • Article
  • Open Access
7 Citations
4,566 Views
17 Pages

Temporal Patterns of Glucagon and Its Relationships with Glucose and Insulin following Ingestion of Different Classes of Macronutrients

  • Christian Göbl,
  • Micaela Morettini,
  • Benedetta Salvatori,
  • Wathik Alsalim,
  • Hana Kahleova,
  • Bo Ahrén and
  • Andrea Tura

16 January 2022

Background: glucagon secretion and inhibition should be mainly determined by glucose and insulin levels, but the relative relevance of each factor is not clarified, especially following ingestion of different macronutrients. We aimed to investigate t...

  • Article
  • Open Access
4 Citations
10,778 Views
13 Pages

16 January 2022

Sufficient dietary protein intake is vital to maintaining muscle health with aging. Yet protein intake among adults is often inadequate. This study’s main objective was to examine the impact of nutrition education (NE) and a per-meal protein pr...

  • Review
  • Open Access
40 Citations
18,495 Views
17 Pages

16 January 2022

Whole grain foods are rich in nutrients, dietary fibre, a range of antioxidants, and phytochemicals, and may have potential to act in an anti-inflammatory manner, which could help impact chronic disease risk. This systematic literature review aimed t...

  • Article
  • Open Access
14 Citations
4,555 Views
14 Pages

Application of a Machine Learning Technology in the Definition of Metabolically Healthy and Unhealthy Status: A Retrospective Study of 2567 Subjects Suffering from Obesity with or without Metabolic Syndrome

  • Davide Masi,
  • Renata Risi,
  • Filippo Biagi,
  • Daniel Vasquez Barahona,
  • Mikiko Watanabe,
  • Rita Zilich,
  • Gabriele Gabrielli,
  • Pierluigi Santin,
  • Stefania Mariani and
  • Lucio Gnessi
  • + 1 author

15 January 2022

The key factors playing a role in the pathogenesis of metabolic alterations observed in many patients with obesity have not been fully characterized. Their identification is crucial, and it would represent a fundamental step towards better management...

  • Review
  • Open Access
41 Citations
6,744 Views
19 Pages

Receptor Mediated Effects of Advanced Glycation End Products (AGEs) on Innate and Adaptative Immunity: Relevance for Food Allergy

  • Daniela Briceno Noriega,
  • Hannah E. Zenker,
  • Cresci-Anne Croes,
  • Arifa Ewaz,
  • Janneke Ruinemans-Koerts,
  • Huub F. J. Savelkoul,
  • R. J. Joost van Neerven and
  • Malgorzata Teodorowicz

15 January 2022

As of late, evidence has been emerging that the Maillard reaction (MR, also referred to as glycation) affects the structure and function of food proteins. MR induces the conformational and chemical modification of food proteins, not only on the level...

  • Review
  • Open Access
29 Citations
10,219 Views
17 Pages

15 January 2022

Dietary habits, that are formed during childhood and consolidated in adulthood, are known to influence the development of future chronic diseases such as metabolic syndrome or type 2 diabetes. The aim of this review was to evaluate the effectiveness...

  • Article
  • Open Access
12 Citations
4,277 Views
18 Pages

Characterizing Individual Differences in Sweet Taste Hedonics: Test Methods, Locations, and Stimuli

  • May M. Cheung,
  • Matthew Kramer,
  • Gary K. Beauchamp,
  • Sari Puputti and
  • Paul M. Wise

15 January 2022

Sweetness drives the consumption of added sugars, so understanding how to best measure sweet hedonics is important for developing strategies to lower sugar intake. However, methods to assess hedonic response to sweetness vary, making results across s...

  • Article
  • Open Access
11 Citations
2,712 Views
14 Pages

15 January 2022

Bladder cancer patients whose tumors develop resistance to cisplatin-based chemotherapy often turn to natural, plant-derived products. Beneficial effects have been particularly ascribed to polyphenols, although their therapeutic relevance when resist...

  • Article
  • Open Access
32 Citations
5,515 Views
15 Pages

15 January 2022

Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus (DM), resulting in high mortality. Myocardial fibrosis, cardiomyocyte apoptosis and inflammatory cell infiltration are hallmarks of DCM, leading to cardiac dysfunction. To da...

  • Review
  • Open Access
7 Citations
6,637 Views
31 Pages

15 January 2022

Maternal dietary micronutrients and omega-3 fatty acids support development of the fetal and neonatal immune system. Whether supplementation is similarly beneficial for the mother during gestation has received limited attention. A scoping review of h...

  • Article
  • Open Access
14 Citations
5,540 Views
14 Pages

Diet and Physical Activity as Determinants of Continuously Measured Glucose Levels in Persons at High Risk of Type 2 Diabetes

  • Su Hyun Park,
  • Jiali Yao,
  • Xin Hui Chua,
  • Suresh Rama Chandran,
  • Daphne S. L. Gardner,
  • Chin Meng Khoo,
  • Falk Müller-Riemenschneider,
  • Clare Whitton and
  • Rob M. van Dam

15 January 2022

We examined how dietary and physical activity behaviors influence fluctuations in blood glucose levels over a seven-day period in people at high risk for diabetes. Twenty-eight participants underwent a mixed meal tolerance test to assess glucose home...

  • Article
  • Open Access
2,190 Views
6 Pages

Presence of Increased Mast Cells in Infants and Children with Volume and Variety Limited Intake

  • Amy Issa,
  • Jensen Edwards,
  • Meenal Singh,
  • Craig Friesen and
  • Sarah Edwards

15 January 2022

Background: Reports indicate patients with feeding difficulties demonstrate signs of inflammation on biopsies, notably eosinophilia, but it is unknown whether mast cell density contributes to variety or volume limitation symptoms. The aim of our stud...

  • Review
  • Open Access
55 Citations
35,584 Views
22 Pages

Prenatal Folate and Choline Levels and Brain and Cognitive Development in Children: A Critical Narrative Review

  • Nathalie Irvine,
  • Gillian England-Mason,
  • Catherine J. Field,
  • Deborah Dewey and
  • Fariba Aghajafari

15 January 2022

Women’s nutritional status during pregnancy can have long-term effects on children’s brains and cognitive development. Folate and choline are methyl-donor nutrients and are important for closure of the neural tube during fetal development...

  • Review
  • Open Access
27 Citations
7,829 Views
36 Pages

In Vitro Methodologies to Study the Role of Advanced Glycation End Products (AGEs) in Neurodegeneration

  • Marialena Chrysanthou,
  • Ignacio Miro Estruch,
  • Ivonne M. C. M. Rietjens,
  • Harry J. Wichers and
  • Tamara Hoppenbrouwers

15 January 2022

Advanced glycation end products (AGEs) can be present in food or be endogenously produced in biological systems. Their formation has been associated with chronic neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease,...

  • Feature Paper
  • Article
  • Open Access
17 Citations
3,288 Views
13 Pages

Associations between Serum Betaine, Methyl-Metabolizing Genetic Polymorphisms and Risk of Incident Type 2 Diabetes: A Prospective Cohort Study in Community-Dwelling Chinese Adults

  • Xiaoting Lu,
  • Rongzhu Huang,
  • Shuyi Li,
  • Aiping Fang,
  • Yuming Chen,
  • Si Chen,
  • Fan Wang,
  • Xinlei Lin,
  • Zhaoyan Liu and
  • Huilian Zhu

15 January 2022

Previous studies have explored associations between betaine and diabetes, but few have considered the effects of genes on them. We aimed to examine associations between serum betaine, methyl-metabolizing genetic polymorphisms and the risk of type 2 d...

  • Article
  • Open Access
4 Citations
2,987 Views
19 Pages

15 January 2022

Undernutrition is highly prevalent in young children in Madagascar and insufficient intake per meal could be one of the main causes. A cross-sectional survey of infant feeding practices including video-recorded meal observations was carried out with...

  • Article
  • Open Access
146 Citations
11,559 Views
9 Pages

Vitamin D Receptor (VDR) Gene Polymorphisms Modify the Response to Vitamin D Supplementation: A Systematic Review and Meta-Analysis

  • Ricardo Usategui-Martín,
  • Daniel-Antonio De Luis-Román,
  • José María Fernández-Gómez,
  • Marta Ruiz-Mambrilla and
  • José-Luis Pérez-Castrillón

15 January 2022

The vitamin D receptor (VDR), a member of the nuclear receptor superfamily of transcriptional regulators, is crucial to calcitriol signalling. VDR is regulated by genetic and environmental factors and it is hypothesised that the response to vitamin D...

  • Article
  • Open Access
10 Citations
3,853 Views
11 Pages

14 January 2022

Carbohydrates play an important role in blood glucose control in pregnant women with GDM. Carbohydrate-restricted dietary (CRD) pattern for gestational diabetes mellitus (GDM) has been widely used in clinics, but the change in insulin utilization rat...

  • Feature Paper
  • Article
  • Open Access
14 Citations
6,382 Views
11 Pages

Food Insecurity and Associated Factors in Brazilian Undergraduates during the COVID-19 Pandemic

  • Bruna Leal Lima Maciel,
  • Clélia de Oliveira Lyra,
  • Jéssica Raissa Carlos Gomes,
  • Priscilla Moura Rolim,
  • Bartira Mendes Gorgulho,
  • Patrícia Simone Nogueira,
  • Paulo Rogério Melo Rodrigues,
  • Tiago Feitosa da Silva,
  • Fernanda Andrade Martins and
  • Dirce Maria Marchioni
  • + 6 authors

14 January 2022

Undergraduates may face challenges to assure food security, related to economic and mental distress, especially during the COVID-19 pandemic. This study aimed to assess food insecurity and its associated factors in undergraduates during the COVID-19...

  • Feature Paper
  • Article
  • Open Access
43 Citations
8,993 Views
20 Pages

When Eating Becomes Torturous: Understanding Nutrition-Related Cancer Treatment Side Effects among Individuals with Cancer and Their Caregivers

  • Brandy-Joe Milliron,
  • Lora Packel,
  • Dan Dychtwald,
  • Cynthia Klobodu,
  • Laura Pontiggia,
  • Ochi Ogbogu,
  • Byron Barksdale and
  • Jonathan Deutsch

14 January 2022

Individuals living with cancer often experience multiple nutrition-related side effects from cancer treatment, including changes in taste and smell, nausea, diarrhea, loss of appetite, and pain during eating. These side effects can profoundly impact...

  • Article
  • Open Access
6 Citations
6,226 Views
9 Pages

Knowledge and Practice of Childbearing Women in Saudi Arabia towards Folic Acid Supplement—Evidence from a Cross-Sectional Study

  • Mohamed N. Al Arifi,
  • Ali M. Alqahtani,
  • Abdulaziz Naif Alotaibi,
  • Salmeen D. Babelghaith,
  • Abdulrahman Alwhaibi,
  • Sary Alsanea,
  • Sultan M. Alghadeer and
  • Nasser M. Al-Arifi

14 January 2022

Background and objectives: Neural tube defects are congenital anomalies which canlead to infant death and serious disability. They are initiated during embryogenesis, between the 23rd and 27th day of fetal life, and can be prevented by the administra...

  • Article
  • Open Access
31 Citations
5,770 Views
17 Pages

The Role of the Western Diet and Oral Microbiota in Parkinson’s Disease

  • Barbara Zapała,
  • Tomasz Stefura,
  • Tomasz Milewicz,
  • Julia Wątor,
  • Monika Piwowar,
  • Magdalena Wójcik-Pędziwiatr,
  • Magdalena Doręgowska,
  • Alicja Dudek,
  • Zuzanna Jania and
  • Monika Rudzińska-Bar

14 January 2022

The type of diet not only affects the composition of the oral microflora but is also one of the more critical factors associated with an increased risk of Parkinson’s disease, PD. This study compared diet preferences and oral microbiota profile...

  • Review
  • Open Access
44 Citations
13,725 Views
19 Pages

Efficacy of Probiotics in Rheumatoid Arthritis and Spondyloarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Pauline Sanchez,
  • Jean-Guillaume Letarouilly,
  • Yann Nguyen,
  • Johanna Sigaux,
  • Thomas Barnetche,
  • Sébastien Czernichow,
  • René-Marc Flipo,
  • Jérémie Sellam and
  • Claire Daïen

14 January 2022

Background: We aimed to provide a systematic review and meta-analysis of randomized controlled trials assessing the effect of probiotics supplementation on symptoms and disease activity in patients with chronic inflammatory rheumatic diseases (rheuma...

  • Article
  • Open Access
22 Citations
14,678 Views
23 Pages

Associations of Nutritional Behavior and Gut Microbiota with the Risk of COVID-19 in Healthy Young Adults in Poland

  • Paweł Jagielski,
  • Edyta Łuszczki,
  • Dominika Wnęk,
  • Agnieszka Micek,
  • Izabela Bolesławska,
  • Beata Piórecka and
  • Paweł Kawalec

14 January 2022

The numerous consequences of the coronavirus disease 2019 (COVID-19) pandemic in healthy young people and the lack of clarity as to the long-term disease outcomes have spurred the search for risk factors for SARS-CoV-2 infection. We aimed to evaluate...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,860 Views
13 Pages

Dietary Exposure to Polychlorinated Biphenyls and Dioxins and Its Relationship to Telomere Length in Subjects Older Than 55 Years from the SUN Project

  • Lucia Alonso-Pedrero,
  • Carolina Donat-Vargas,
  • Maira Bes-Rastrollo,
  • Ana Ojeda-Rodríguez,
  • Guillermo Zalba,
  • Cristina Razquin,
  • Miguel A. Martínez-González and
  • Amelia Marti

14 January 2022

Exposure to persistent organic pollutants (POPs) may influence telomere length (TL), which is considered as a marker of biological age associated with the risk of chronic disease. We hypothesized that dietary exposure to polychlorinated biphenyls (PC...

  • Feature Paper
  • Article
  • Open Access
17 Citations
3,888 Views
16 Pages

Monocyte-to-HDL Ratio (MHR) Predicts Vitamin D Deficiency in Healthy and Metabolic Women: A Cross-Sectional Study in 1048 Subjects

  • Carlo De Matteis,
  • Lucilla Crudele,
  • Marica Cariello,
  • Stefano Battaglia,
  • Giuseppina Piazzolla,
  • Patrizia Suppressa,
  • Carlo Sabbà,
  • Elena Piccinin and
  • Antonio Moschetta

14 January 2022

Vitamin D deficiency is often linked with Metabolic Syndrome, both being more frequent with ageing and associated with an increase inflammatory state. Recently, monocytes-to-high density lipoprotein (HDL) ratio (MHR) has emerged as a powerful index t...

  • Review
  • Open Access
25 Citations
13,339 Views
16 Pages

Nutritional Approach to Cancer Cachexia: A Proposal for Dietitians

  • Kotone Tanaka,
  • Sho Nakamura and
  • Hiroto Narimatsu

14 January 2022

Cachexia is one of the most common, related factors of malnutrition in cancer patients. Cancer cachexia is a multifactorial syndrome characterized by persistent loss of skeletal muscle mass and fat mass, resulting in irreversible and progressive func...

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Nutrients - ISSN 2072-6643