2025 October-2 - 116 articles
In the context of the study of G-quadruplex (G4), the main field of focus is usually referred to binding molecules able to interact with these non-canonical conformations and stabilizing them leading to diverse biological effects. Although the cellul...
Lavandin essential oil (LEO) (Lavandula × intermedia) is a high-yielding aromatic product with broad bioactive potential, but its direct application is hindered by its volatility, rapid oxidation, and environmental sensitivity. In this study, t...
The dehydration of fructose and glucose to 5-hydroxymethylfurfural (HMF) in water solution was carried out in the presence of functionalized heteropolyanion-based heterogeneous catalysts. Two catalysts were prepared by immobilizing the Keggin polyoxo...
6-Nitrodopamine is an endogenous catecholamine responsible for numerous biological activities. Here, an improved method for the synthesis of both 6-nitrohomovanillic acid (6-NHVA) and its regioisomer 5-nitrohomovanillic acid (5-NHVA) is reported. The...
Advanced glycation end products (AGEs) derived from food are compounds readily formed during heating and processing through non-enzymatic glycation reactions such as the Maillard reaction. Since a variety and quantity of AGEs are formed within shorte...
Background: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia driven by the PML/RARα fusion protein. Standard treatment with all-trans retinoic acid (ATRA) combined with chemotherapy is effective, but resistance and adve...
In continuation of our recent report on the in vitro activity of sandalwood essential oils and their major components, the sesquiterpenes (Z)-α- and -β-santalols, against the pathogenic fungus Madurella mycetomatis, causative agent of the...
This study investigated the contamination, composition, and functional properties of Wolffia globosa from northern Thailand. The results showed that the heavy metal content of dried W. globosa complied with Thai regulations, ensuring its safety. Its...
N6-methyladenosine (m6A) modifications are among the most prevalent epigenetic marks in eukaryotic RNAs, regulating both coding and non-coding RNAs and playing a pivotal role in RNA metabolism. Given their widespread influence, m6A modifications are...
Fungal-derived bioactive compounds are emerging as key components in functional food development, offering new opportunities for health-promoting formulations. The Polyporaceae family, particularly Cerrena unicolor, has demonstrated significant poten...
Polybutylene succinate (PBS), as one of the most promising multi-application polymer, still suffers from low toughness, poor miscibility, and high crystallinity. Blending with starch is an effective strategy to improve the properties of PBS, but the...
Cereal grains make up a significant part of both human and animal diets; therefore, they should meet pesticide residue standards and be characterized by the lowest possible concentrations of these residues. Known for its strong oxidizing properties,...
Quinolizidine alkaloids, found particularly in leguminous plants (Fabaceae), are known for their role in plant protection, acting as toxic secondary metabolites against pests and pathogens. However, their toxicity also makes them anti-nutritional fac...
Organophosphorus chemical warfare agents such as sarin (GB), soman (GD), and cyclosarin (GF) rank among the most toxic substances known, making trace-level detection critical for public and military safety. In this study, we compared the sensitivity...
The thermal and optical properties of aqueous dispersions of magnetite nanoparticles were studied by dual-beam thermal-lens spectrometry. Surface-modified magnetite nanoparticles with an average crystal size of 7.5 nm were synthesized by a simple, on...
This study examined the cosmetic potential of extracts from the peel and pulp of fermented pumpkin (Cucurbita pepo L.). Fermentation was carried out using Lactobacillus strains (L. plantarum, L. rhamnosus, L. fermentum, and L. paracasei) and kombucha...
Nectar composition varies across plant species and environments, influencing pollinator interactions and honey quality. Reliable methods for nectar discrimination, however, remain limited. Here, we demonstrate the use of Fourier-transform infrared (F...
Tyrosinase is a key enzyme in melanogenesis, playing an important role in skin, hair, and eye pigmentation, as well as in the enzymatic browning of fruits and vegetables. Excessive tyrosinase activity leads to hyperpigmentation and other dermatologic...
In this study, first-principles calculations were employed to systematically investigate the interaction mechanisms between (18-crown-6) potassium (18C6-K+) and six typical defect sites on the SnO2 (110) surface, including Sni + SnO, Oi + OSn, VO + S...
The chemical profile of coffee depends on numerous factors, the complexity of which makes it difficult to clearly assess their influence. The aim of this study was to comprehensively evaluate the impact of selected coffee brewing methods (Espresso, S...
This article reviews recent advances in heterogeneous hydroformylation, with a particular focus on rhodium-based catalysts supported on oxide surfaces. The hydroformylation reaction is a vital industrial process for producing aldehydes from petrochem...
Traditional sample preparation for terpene analysis includes distillation, solvent extraction, and solid phase extraction and is followed by using gas chromatography with a mass spectrometer (GC-MS) to complete identification and quantification. The...
Serpentinite rocks and their processing waste represent a valuable source of magnesium and silicon; however, their complex composition complicates the efficient recovery of individual components. This study investigates the combined acid–alkali...
Specific expression of genes is fundamental for defining the identity and the functional state of cells. Sequence-specific transcription factors interpret the information contained in DNA sequence motifs and recruit cofactors to modify chromatin and...
As a traditional Chinese medicinal herb, Centipeda minima (L.) A. Braun & Asch is known for its effects in dispersing wind-cold, clearing nasal passages, and relieving coughs. Current research has identified various chemical constituents isolated...
With environmental pollution and energy shortages becoming increasingly severe, developing efficient energy conversion and storage technologies is crucial. Cu2Se has garnered significant attention as a thermoelectric material due to its abundant raw...
Jin’er (Naematelia aurantialba), commonly known as golden ear, is a traditional edible fungus that has long been recognized for its medicinal and culinary properties in China. Recently, it has been registered as a new cosmetic ingredient, drawi...
The antibacterial properties of Ag(I) coordination compounds are well documented; however, their effectiveness is highly dependent on the choice of appropriate ligands, and it is frequently hindered by their low water solubility and limited bioavaila...
The ultrasound-assisted antisolvent precipitation method was used to prepare lignin nanoparticles from Thlaspi arvense L. rhizomes. The influence of each experimental variable on the average particle size (APS) of the lignin nanoparticles was determi...
Astragalus aitosensis, also known as Astracantha arnacantha (M. Bieb.) Podlech subsp. aitosensis (Ivanisch.) Réer & Podlech, a Bulgarian endemic species, was investigated for its phenolic profile and neuroprotective potential. A targeted e...
Antimony (Sb), as a toxic heavy metal, has drawn worldwide attention, and its efficient removal from water has become increasingly urgent. In this study, an iron-modified alkaline lignin chitosan (Fe-ALCS) gel bead is prepared by the freeze-drying me...
Six previously undescribed sesquiterpenoids, aurantiophilanes A–F (1–6), along with six identified analogues (7–12), were isolated from the fungus Aspergillus aurantiobrunneus. Among these, compounds 1 and 3 were identified as highl...
Human remains detection (HRD) dogs are vital tools in forensic science and disaster response, but their training is limited by the restricted availability of human material. Synthetic odorants such as Sigma Pseudo™ formulations provide safer, s...
Terpenes, representing one of the most extensive classes of natural products, hold significant value in the fields of pharmaceuticals, fragrances, and biofuels. Extracting these compounds from natural sources is often environmentally unsustainable, a...
In this study, core–shell Ln2O3@carbon nanoparticles (core = Ln2O3 and shell = carbon; Ln = Tb and Ho) were synthesized for the first time by preparing Ln2O3 nanoparticles through a polyol method, followed by carbon coating using D-glucose as a...
This study reports the synthesis and comprehensive spectroscopic characterization of 4-indolylcyanamide (4ICA), a novel indole-derived infrared (IR) probe designed for assessing local microenvironments in biological systems. 4ICA was synthesized via...
Developing bifunctional electrocatalysts that simultaneously enable green hydrogen production and water purification is essential for advancing sustainable energy and environmental technologies. In this study, we present Cu@Pd core–shell nanost...
Cross-linked polymers are indispensable in advanced applications, but suffer from poor recyclability due to permanent covalent networks. Herein, we report recyclable supramolecular polyurea elastomers that integrate ureidopyrimidinone-based quadruple...
Hypocrellin A (HA), a photodynamic perylenequinone pigment from Shiraia fruiting bodies, functions as an efficient photosensitizer for clinical photodynamic therapy. Glucose-6-phosphate dehydrogenase (G6PDH), the rate-limiting enzyme of the pentose p...
Oenothera biennis L. is a biennial species native to North America and introduced to Europe in the 17th–18th centuries, used in traditional medicine or as a dietary supplement in various products, as well as in cosmetics and the pharmaceutical...
Electric arc furnace (EAF) waste, a mixture of dust and slag, was investigated as a potential secondary source of zinc. The waste primarily consisted of zinc and iron oxides, with the presence of refractory zinc ferrite, which hinders the complete re...
Ammonia borane is a promising hydrogen storage material due to its high hydrogen content, but its use as hydrogen carrier under thermal stimuli involves the production of several byproducts, such as borazine, reducing hydrogen purity and the overall...
Hydrogen atom transfer (HAT) is a fundamental class of radical transformations that enables the direct generation of open-shell radical intermediates from R–H bonds (R = C, N, etc.), offering unique opportunities for green and sustainable synth...
Virus-like particles (VLPs) formed as a result of self-assembly of viral capsid proteins are widely used as a platform for antigen presentation in vaccine development. However, since the inclusion of a foreign peptide into the capsid protein can alte...
The unimolecular alkene elimination reaction class of fatty acid alkyl esters (FAAEs) is a crucial component in the low-temperature combustion mechanism for biodiesel fuels. However, thermo-kinetic parameters for this reaction class are scarce, parti...
The Jurubatiba Sandbank National Park (PARNA Jurubatiba) is an ecological reserve characterized by harsh environmental conditions, including low rainfall, high sun exposure, and sandy soil. Among its native vegetation, Eremanthus crotonoides stands o...
Marine protected areas (MPAs) near the coast are a global concern due to potential impact of anthropogenic activities highly relevant when it comes to trace elements pollution in sediment. This study aims to assess the levels of trace elements in sed...
In this work, we synthesized a small library of tricyclic compounds to assess whether they might have both anticancer and antiviral activity against three viruses that have recently caused epidemics. Concerning their anti-tumour activity, derivative...
Nowadays deodorants and antiperspirants play an important role in maintaining daily hygiene, exerting a substantial influence on both physical comfort and social functioning. Consequently, they can be regarded as a pivotal component of contemporary p...
Tunicamycins trigger endoplasmic reticulum (ER) stress by inhibiting DPAGT1 (dolichyl-phosphate N-acetylglucosamine-phosphotransferase 1): the rate-limiting enzyme that initiates N-glycan biosynthesis. Aberrant N-glycan branching is a hallmark of man...
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