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Molecules, Volume 30, Issue 20

October-2 2025 - 116 articles

Cover Story: Silver(I) coordination compounds are promising antibacterial agents, but their efficacy is often limited by poor solubility and bioavailability, both of which are strongly influenced by ligand choice. In this work, a group of six new Ag(I) complexes featuring a quinazolinone thioamide and different phosphine co-ligands were synthesized and evaluated for their antibacterial properties, revealing selective growth inhibition of S. aureus. To enhance their effectiveness, Ag(I) complexes were encapsulated into alginate-based hydrogels, which enabled antibacterial activity at significantly lower concentrations. Mechanistic studies suggest a redox-mediated bioactivity via reductase inhibition and subsequent disruption of bacterial redox homeostasis. View this paper
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Articles (116)

  • Article
  • Open Access
819 Views
15 Pages

21 October 2025

An efficient method for the simultaneous extraction of cannabinoids and terpenes from the leaves and flowers of Cannabis sativa L. (var. Felina 32) was developed. Extraction parameters, including solvent type, temperature, and pressure, were optimize...

  • Article
  • Open Access
1,192 Views
22 Pages

Bioactivity and Compound Identification in Extracts from Three Australian Populations of Portulaca oleracea: Full NMR Structural Characterisation of Oleracein Australis 1

  • Colette Geier,
  • Rachael Micklewright,
  • Russell Barrow,
  • Joanne F. Jamie,
  • Paul D. Prenzler,
  • Danielle Ryan and
  • Lachlan Schwarz

21 October 2025

Three Australian populations of Portulaca oleracea—Common Purslane, Omega Gold and Omega Red—were grown under identical conditions, separated into portions—leaf, bud, stem and root—and their extracts tested for total phenolic...

  • Article
  • Open Access
1 Citations
776 Views
15 Pages

21 October 2025

In the search for new materials to open up creative pathways for industry and research, modification is one of the best methods to implement. Developing materials with high sensitivity and selectivity for specific applications, such as ion sensing, r...

  • Article
  • Open Access
498 Views
17 Pages

21 October 2025

Considering the relevance of hydrogen bonds and other intermolecular interactions in regulating the activity of the tyrosine kinase class of enzymes, an in-depth electronic structure study of these forces in the context of the BCR-ABL protein was per...

  • Article
  • Open Access
604 Views
29 Pages

Uranyl(VI) Interaction with 2-Phosphonobutane-1,2,4-Tricarboxylic Acid (PBTC): A Spectroscopic and Computational Study over a Wide pH Range

  • Jerome Kretzschmar,
  • Anne Wollenberg,
  • Ion Chiorescu,
  • Sven Krüger,
  • Ronja Kraft,
  • Michael U. Kumke,
  • Satoru Tsushima,
  • Katja Schmeide and
  • Margret Acker

21 October 2025

Organophosphonates have manifold applications in the chemical industry, of which one of the most commonly used is 2-phosphonobutane-1,2,4-tricarboxylic acid (PBTC). It is widely used as a cement additive and may pose a potential risk of complexing ra...

  • Review
  • Open Access
1,585 Views
32 Pages

21 October 2025

Owing to the inherent safety, environmental friendliness, and high theoretical capacity (820 mAh g−1) of zinc metal, aqueous zinc-ion batteries (AZIBs) have emerged as up-and-coming alternatives to organic lithium-ion batteries. However, the in...

  • Article
  • Open Access
423 Views
13 Pages

21 October 2025

This study investigates, for the first time, the relationship between carbon (δ13C) and nitrogen stable isotopic composition of Aspergillus niger mycelium, used as chitin and chitosan sources, and the fungus diet under controlled cultivation co...

  • Article
  • Open Access
406 Views
20 Pages

21 October 2025

The rapid development of the silicon industry has led to the massive production of silica fume (SF), while its improper disposal poses environmental risks and represents a waste of resources. Unlike conventional methods that require dissolution and h...

  • Article
  • Open Access
1,173 Views
38 Pages

Characterization of Essential Oils and Ethanolic Extracts from Nine Pepper Species: Antioxidant and Antimicrobial Activity and Spectroscopic Analysis

  • Aleksandra Sander,
  • Maja Bival Štefan,
  • Tea Sander,
  • Dajana Kučić Grgić,
  • Jelena Parlov Vuković,
  • Iva Blažević and
  • Jasna Jablan

20 October 2025

This study examined the characteristics of essential oils and ethanolic extracts from nine pepper species’ fruits to determine their chemical compositions and assess their biological activity. Ethanolic extracts and essential oils were analyzed...

  • Article
  • Open Access
534 Views
28 Pages

TiO2 and CaCO3 Microparticles Produced in Aqueous Extracts from Satureja montana: Synthesis, Characterization, and Preliminary Antimicrobial Test

  • Federica Valentini,
  • Irene Angela Colasanti,
  • Camilla Zaratti,
  • Dumitrita Filimon,
  • Andrea Macchia,
  • Anna Neri,
  • Michela Relucenti,
  • Massimo Reverberi,
  • Ivo Allegrini and
  • Ettore Guerriero
  • + 9 authors

20 October 2025

The possibility of modifying the surface chemistry of materials and synthetizing inorganic particles in natural aqueous extracts of plants (avoiding calcination), opens the doors to undoubtedly interesting scenarios for innovative functionalization s...

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Molecules - ISSN 1420-3049