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27 Results Found

  • Review
  • Open Access
17 Citations
10,311 Views
24 Pages

Uncovering Challenges and Pitfalls in Identifying Threshold Concepts: A Comprehensive Review

  • Paulo R. M. Correia,
  • Ivan A. I. Soida,
  • Izabela de Souza and
  • Manolita C. Lima

30 January 2024

The exploration of threshold concepts, which represent a transformed way of understanding, interpreting, or viewing something necessary for a learner’s progress, has significantly influenced teaching and learning in higher education, gaining br...

  • Review
  • Open Access
34 Citations
5,822 Views
25 Pages

Plants as the Extended Phenotype of Endophytes—The Actual Source of Bioactive Compounds

  • Natalia Rutkowska,
  • Piotr Drożdżyński,
  • Małgorzata Ryngajłło and
  • Olga Marchut-Mikołajczyk

For thousands of years, plants have been used for their medicinal properties. The industrial production of plant-beneficial compounds is facing many drawbacks, such as seasonal dependence and troublesome extraction and purification processes, which h...

(This article belongs to the Special Issue Molecular Plant-Microbe Interactions 2.0)
  • Review
  • Open Access
91 Citations
36,875 Views
17 Pages

Current Overview on Clinical Management of Chronic Constipation

  • Jakub Włodarczyk,
  • Anna Waśniewska,
  • Jakub Fichna,
  • Adam Dziki and ,
  • Łukasz Dziki and
  • Marcin Włodarczyk
  • + 1 author+ 0 author

16 April 2021

Constipation is one of the major gastrointestinal disorders diagnosed in clinical practice in Western countries. Almost 20% of population suffer from this disorder, which means constipation is a substantial utilization of healthcare. Pathophysiology...

(This article belongs to the Special Issue Enteric Nervous System: Neuropathic Gastrointestinal Motility)
  • Feature Paper
  • Article
  • Open Access
770 Views
13 Pages

27 October 2025

In the study of linear dispersive media, it is of primary interest to gain knowledge of the impulse response of the material. The standard approach to compute the response involves a Laplace transform inversion, i.e., the solution of a Bromwich integ...

(This article belongs to the Section C1: Difference and Differential Equations)
  • Review
  • Open Access
8 Citations
6,770 Views
17 Pages

Novel Treatments in Refractory Recurrent Pericarditis

  • Emilia Lazarou,
  • Christos Koutsianas,
  • Panayotis K. Vlachakis,
  • Panagiotis Theofilis and ,
  • Dimitrios Vassilopoulos,
  • Costas Tsioufis,
  • George Lazaros and
  • Dimitris Tousoulis
  • + 3 authors+ 0 author

15 August 2024

Refractory recurrent pericarditis is a troublesome condition that severely impairs the quality of life of affected patients and significantly increases healthcare spending. Until recently, therapeutic options included only a few medications and most...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
16 Citations
5,679 Views
13 Pages

13 November 2019

The concept of site-specific weed management is based on the assumption that weeds are aggregated in patches. In this study, we surveyed four plots in four commercial almond orchards for three years and mapped the locations of Ecballium elaterium, a...

(This article belongs to the Special Issue Weed Management & New Approaches)
  • Review
  • Open Access
205 Citations
23,530 Views
20 Pages

Focus on the Primary Prevention of Intrauterine Adhesions: Current Concept and Vision

  • Wen-Ling Lee,
  • Chia-Hao Liu,
  • Min Cheng,
  • Wen-Hsun Chang and ,
  • Wei-Min Liu and
  • Peng-Hui Wang
  • + 1 author+ 0 author

Intrauterine adhesion (IUA), and its severe form Asherman syndrome (Asherman’s syndrome), is a mysterious disease, often accompanied with severe clinical problems contributing to a significant impairment of reproductive function, such as menstrual di...

(This article belongs to the Section Materials Science)
  • Review
  • Open Access
46 Citations
20,624 Views
13 Pages

Rethinking the Dental Amalgam Dilemma: An Integrated Toxicological Approach

  • Hector Jirau-Colón,
  • Leonardo González-Parrilla,
  • Jorge Martinez-Jiménez,
  • Waldemar Adam and
  • Braulio Jiménez-Velez

Mercury (Hg) has been identified as one of the most toxic nonradioactive materials known to man. Although mercury is a naturally occurring element, anthropogenic mercury is now a major worldwide concern and is an international priority toxic pollutan...

(This article belongs to the Special Issue Heavy Metal Pollution and Health Risk Assessment)
  • Review
  • Open Access
54 Citations
6,585 Views
10 Pages

20 May 2020

Siloxanes are among the most technologically troublesome trace compounds present in biogas. As a result of their combustion, hard-to-remove sediments are formed, blocking biogas energy processing devices and reducing the efficiency of biogas plants....

(This article belongs to the Special Issue Energy Processes, Systems and Equipment)
  • Article
  • Open Access
37 Citations
6,016 Views
19 Pages

15 May 2019

Device-assisted therapies (DAT) benefit people with Parkinsons Disease (PwP) but many referrals for DAT are unsuitable or too late, and a screening tool to aid in identifying candidates would be helpful. This study aimed to produce such a screening t...

(This article belongs to the Special Issue Wearable, Smart, Pervasive, and Unconventional Sensing for Health Monitoring: Solutions from Today and for Tomorrow)
  • Article
  • Open Access
9 Citations
9,388 Views
21 Pages

Implementation of Deep-Learning-Based CSI Feedback Reporting on 5G NR-Compliant Link-Level Simulator

  • Daniel Gaetano Riviello,
  • Riccardo Tuninato,
  • Elisa Zimaglia,
  • Roberto Fantini and
  • Roberto Garello

12 January 2023

Advances in machine learning have widened the range of its applications in many fields. In particular, deep learning has attracted much interest for its ability to provide solutions where the derivation of a rigorous mathematical model of the problem...

(This article belongs to the Special Issue Experimentation in 5G and beyond Networks: State of the Art and the Way Forward)
  • Article
  • Open Access
4 Citations
1,630 Views
17 Pages

8 March 2025

Water resources in the European Union are diverse. For example, Croatia has almost 18 times the water resources that Poland has. Although the key factor causing water shortages is population growth, in Poland this crisis is primarily determined by dy...

  • Article
  • Open Access
6 Citations
3,540 Views
17 Pages

1 February 2019

The success of medication adjustment in Parkinson’s disease (PD) patients with motor fluctuation relies on the knowledge about their fluctuation severity. However, because of the temporal and spatial variability in motor fluctuations, a single...

(This article belongs to the Section Information Theory, Probability and Statistics)
  • Article
  • Open Access
5 Citations
2,462 Views
11 Pages

A Child with Crohn’s Disease: Problems and Stress Level of Parents–Caregivers—A Cross-Sectional Study

  • Małgorzata Pasek,
  • Monika Stoietskyi,
  • Anna Goździalska and
  • Małgorzata Jochymek

16 February 2024

Crohn’s disease (CD) is a chronic inflammatory bowel disease. The perception of the disease, its troublesome symptoms and the highly involved treatment mean that living with CD requires not only the affected child having to learn to cope with i...

  • Article
  • Open Access
16 Citations
3,377 Views
12 Pages

30 August 2020

It has been widely underlined that both gynaecological malignancies and urogynaecological disorders are often associated with high stress and have a negative impact on the quality of life and psychological well-being of women affected. Knowledge of t...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
  • Best Paper Award
74 Citations
13,147 Views
25 Pages

16 April 2020

The aim of this paper is to examine the role of thermodynamics, and in particular, entropy, for the development of economics within the last 150 years. The use of entropy has not only led to a significant increase in economic knowledge, but also to t...

(This article belongs to the Special Issue Complexity in Economic and Social Systems)
  • Article
  • Open Access
10 Citations
3,826 Views
39 Pages

Geoheritage and Geoconservation, from Theory to Practice: The Ghost Town of Craco (Matera District, Basilicata Region, Southern Italy)

  • Mario Bentivenga,
  • Eva Pescatore,
  • Marco Piccarreta,
  • Fabrizio Terenzio Gizzi and ,
  • Nicola Masini and
  • Salvatore Ivo Giano
  • + 1 author+ 0 author

27 March 2024

Several theoretical and applied studies are concerned with the topics of geological heritage management and geoconservation. The diversity of natural and anthropic scenarios into which geological heritage is inserted, as well as its troublesome manag...

(This article belongs to the Section Tourism, Culture, and Heritage)
  • Case Report
  • Open Access
4 Citations
4,247 Views
10 Pages

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

  • Agnese Grinevica,
  • Agnese Udre,
  • Arturs Balodis and
  • Ilze Strumfa

13 January 2024

Chronic cough in children and adolescents can be troublesome both to the patient and the whole family. The most common causes of chronic cough in children are protracted bacterial bronchitis and bronchial asthma. However, differential diagnostic work...

(This article belongs to the Special Issue Anxious Brain: Stress Influence on the Nervous System)
  • Technical Note
  • Open Access
9 Citations
3,320 Views
16 Pages

30 May 2023

The accurate estimation of ocean tide loading displacements is essential and necessary for geodesy, oceanic and geophysical studies. It is common knowledge that K1 and K2 tidal constituents estimated from Global Positioning System (GPS) observations...

(This article belongs to the Special Issue Remote Sensing and Numerical Simulation for Tidal Dynamics)
  • Article
  • Open Access
19 Citations
3,532 Views
11 Pages

Rapid Identification of Different Grades of Huangshan Maofeng Tea Using Ultraviolet Spectrum and Color Difference

  • Danyi Huang,
  • Qinli Qiu,
  • Yinmao Wang,
  • Yu Wang and ,
  • Yating Lu,
  • Dongmei Fan and
  • Xiaochang Wang
  • + 2 authors+ 0 author

13 October 2020

Tea is an important beverage in humans’ daily lives. For a long time, tea grade identification relied on sensory evaluation, which requires professional knowledge, so is difficult and troublesome for laypersons. Tea chemical component detection...

  • Review
  • Open Access
143 Citations
29,414 Views
12 Pages

1 November 2018

Milk is a fundamental component of the diet of every mammal; nevertheless, not every individual can tolerate this kind of food, especially in adulthood. However, lactose intolerance has only been recognized in the last 50 years, and currently, lactos...

  • Article
  • Open Access
10 Citations
4,586 Views
13 Pages

Background: Rat infestation is a major public health issue globally, and particularly in poor urban communities in South Africa. Rats pose significant threats to residents in the form of disease spread and sustained physical injuries. The dearth of k...

(This article belongs to the Section Environmental Health)
  • Article
  • Open Access
1 Citations
610 Views
33 Pages

Biogas in The Netherlands: Hesitant Adoption on Many Levels

  • Gideon A. H. Laugs and
  • Henny J. van der Windt

23 April 2026

Energy transition includes the substitution of centralized energy systems with decentralized variable renewable energy sources (vRES), the growth of which brings drawbacks such as grid congestion and intermittency. These issues are increasingly troub...

(This article belongs to the Special Issue Renewable Fuels: A Key Step Towards Global Sustainability)
  • Article
  • Open Access
25 Citations
12,764 Views
16 Pages

Interactions between people and large carnivores on shared landscapes can have harmful social and ecological consequences. Human–carnivore coexistence depends on an assemblage of sociological factors including effective management institutions...

  • Opinion
  • Open Access
8 Citations
8,952 Views
11 Pages

Improving Diagnosis and Management of Opioid-Induced Constipation (OIC) in Clinical Practice: An Italian Expert Opinion

  • Giustino Varrassi,
  • Giuseppe Casale,
  • Maria Grazia De Marinis,
  • Francesco Dentali and ,
  • Paolo Evangelista,
  • Gino Gobber,
  • Gaetano Lanzetta,
  • Pierangelo Lora Aprile,
  • Maria Caterina Pace and
  • Andrea Ungar
  • + 7 authors+ 2 authors

7 November 2024

Opioid-induced constipation (OIC) is a very common and troublesome gastrointestinal side effect following the use of opioids. Despite existing international guidelines, OIC is largely underdiagnosed and undertreated. ECHO OIC is a European project de...

(This article belongs to the Section Pharmacology)
  • Review
  • Open Access
23 Citations
11,803 Views
24 Pages

19 August 2025

Invasive fungal infections (IFIs) are one of the most significant public health challenges worldwide. Yet, research and communication thereof were left behind for a long time, until the WHO published a priority pathogens list to guide research, devel...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
16 Citations
6,191 Views
15 Pages

The Spaces of Peer-Led Support Groups for Suicide Bereaved in Denmark and the Republic of Ireland: A Focus Group Study

  • Lisbeth Hybholt,
  • Agnes Higgins,
  • Niels Buus,
  • Lene Lauge Berring and ,
  • Terry Connolly,
  • Annette Erlangsen and
  • Jean Morrissey
  • + 2 authors+ 0 author

Research has shown that people bereaved by suicide have an increased risk of mental health problems, suicidality and associated stigma, as well as higher rates of sick leave and increased rates of receiving disability pensions. Peer-led suicide berea...

(This article belongs to the Special Issue Suicide Bereavement and Postvention: Advances in Research, Practice and Policy)